Publikationen
Publikationen
Alberione MP, Moeller R, Kirui J, Ginkel C, Doepke M, Stroh LJ, Machtens JP, Pietschmann T, Gerold G (2020) Single-nucleotide variants in human CD81 influence hepatitis C virus infection of hepatoma cells. Med Microbiol Immunol (in press). PMID 32322956
Gerold G, Moeller R, Pietschmann T (2020) Hepatitis C Virus Entry: Protein Interactions and Fusion Determinants Governing Productive Hepatocyte Invasion. Cold Spring Harb Perspect Med 10(2). PMID 31427285
Uckeley ZM, Moeller R, Kuhn LI, Nilsson E, Robens C, Lasswitz L, Lindqvist R, Lenman A, Passos V, Voss Y, Sommerauer C, Kampmann M, Goffinet C, Meissner F, Overby AK, Lozach PY, Gerold G (2019) Quantitative proteomics of Uukuniemi virus - host cell interactions reveals GBF1 as proviral host factor for phleboviruses. Mol Cell Proteomics 18(12): 2401-2417. PMID 31570497
Moreno H, Moeller R, Fedeli C, Gerold G, Kunz S (2019) Comparison of the innate immune response to pathogenic and non-pathogenic Clade B New World arenaviruses. J Virol. 93(19). PMID 31270228
Herrador A, Fedeli C, Radulovic E, Moreno H, Campbell K, Gerold G*, and Kunz S* (2019) Dynamic dystroglycan complexes mediate cell entry of Lassa virus. mBio 26;10(2)*co-corresponding. PMID:30914516
Zapatero-Belinchón FJ , Dietzel E , Dolnik O, Döhner K, Costa R, Hertel B, Veselkova B, Kirui J, Klintworth A, Manns MP, Pöhlmann SH, Pietschmann T, Krey T, Ciesek S, Gerold G, Sodeik B, Becker S, von Hahn T. Characterization of the filovirus resistant cell line SH-SY5Y reveals redundant role of cell surface entry factors. Viruses. 2019 Mar 19;11(3). PMID:30893855
Abere B, Samarina N, Gramolelli S, Rückert J, Gerold G, Pich A, Schulz TF. (2018) The Kaposi Sarcoma Herpesvirus non-structural membrane protein pK15 recruits the class II PI3K Phosphatidylinositol 4-phosphate 3-kinase C2 alpha to activate productive viral replication. J Virol. 92(17). PMID: 29950425
Bruening J, Lasswitz L, Banse P, Kahl S, Vondran FW, Kaderali L, Marinach C, Silvie O, Pietschmann T, Meissner F*, Gerold G*. (2018) Hepatitis C virus enters liver cells using the CD81 receptor complex proteins calpain-5 and CBLB. PLOS Pathog. 14(7): e1007111.* these authors contributed equally
Banse P, Moeller R, Bruening J, Lasswitz L, Kahl S, Khan AG, Marcotrigiano J, Pietschmann T, Gerold G (2018) CD81 Receptor Regions outside the Large Extracellular Loop Determine Hepatitis C Virus Entry into Hepatoma Cells. Viruses 10(4). PMID: 29677132
Fedeli C, Torriani G, Galan-Navarro C, Moraz ML, Moreno H, Gerold G, Kunz S (2018) Axl Can Serve as Entry Factor for Lassa Virus Depending on the Functional Glycosylation of Dystroglycan. J Virol 92(5). PMID: 29237830
Gerold G, Bruening J, Weigel B, Pietschmann T. (2017) Protein interactions during the flavivirus and hepacivirus life cycle. Mol Cell Proteomics. 16(4 suppl 1): S75-S91. PMID: 28077444
Bruening J, Weigel B, and Gerold G. (2017) The role of type III interferons in hepatitis C virus infection and therapy. J Immunol Res 2017: 7232361. PMID: 28255563
Gerold G, Bruening J, Pietschmann T. (2015) Decoding protein networks during virus entry by quantitative proteomics. Virus Research. 218: 25-39. PMID: 26365680
von Schaewen M, Dorner M, Hueging K, Foquet L, Gerges S, Hrebikova G, Heller B, Bitzegeio J, Doerrbecker J, Horwitz J, Gerold G, Suerbaum S, Rice CM, Meuleman P, and Pietschmann T, Ploss A (2016) Expanding the host range of hepatitis C virus through viral adaptation. MBio. 2016 Nov 8;7(6). PMID: 27834208
Vieyres G, Welsch K, Gerold G, Gentzsch J, Kahl S, Vondran FW, Kaderali L, Pietschmann T. (2016) ABHD5/CGI-58, the Chanarin-Dorfman Syndrome Protein, Mobilises Lipid Stores for Hepatitis C Virus Production. PLoS Pathogens. 28;12(4):e1005568. PMID:27124600
Lump E, Castellano LM, Meier C, Seeliger J, Erwin N, Sperlich B, Stürzel CM, Usmani S, Hammond RM, von Einem J, Gerold G, Kreppel F, Bravo-Rodriguez K, Pietschmann T, Holmes VM, Palesch D, Zirafi O, Weissman D, Sowislok A, Wettig B, Heid C, Kirchhoff F, Weil T, Klärner FG, Schrader T, Bitan G, Sanchez-Garcia E, Winter R, Shorter J*, and Münch J*. (2015) A molecular tweezer antagonizes seminal amyloids and HIV infection. eLife. 4:e05397. PMID: 26284498
Gerold G, Meissner F, Bruening J, Welsch K, Perin PM, Thomas F. Baumert, Vondran FW, Kaderali L, Marcotrigiano J, Khan AG, Mann M, Rice CM, Pietschmann T. (2015) Quantitative Proteomics Identifies Serum Response Factor Binding Protein 1 as a Host Factor for Hepatitis C Virus Entry. Cell Reports. 4;12(5):864-78.
PMID: 26212323
Scull MA, Shi C, de Jong YP, Gerold G, Ries M, von Schaewen M, Donovan BM, Labitt RN, Horwitz JA, Gaska JM, Hrebikova G, Xiao JW, Flatley B, Fung C, Chiriboga L, Walker CM, Evans DT, Rice CM, Ploss A. (2015) Hepatitis C virus infects rhesus macaque hepatocytes and simianized mice. Hepatology. 62(1):57-67. PMID: 25820364
Gerold G, Pietschmann T. (2014) The HCV life cycle: In vitro tissue culture systems and therapeutic targets. Digestive Diseases. 32(5):525-37. PMID:25034285
Gerold G, Pietschmann T. (2014) A circuit of paracrine signals between liver sinusoid endothelial cells and hepatocytes regulates hepatitis C virus replication. Hepatology. 59(2):363-5. PMID: 2385746
Gerold G, Pietschmann T. (2013) Opportunities and risks of host-targeting antiviral strategies for hepatitis C. Current Hepatitis Reports. 12(4): 200-213.
Gerold G, Pietschmann T. (2013) Hepatitis C virus NS5B polymerase primes innate immune signaling. Hepatology. 57(3):1275-7. PMID: 23426794
Vogt A, Scull MA, Friling T, Horwitz JA, Donovan BM, Dorner M, Gerold G, Labitt RN, Rice CM, Ploss A. (2013) Recapitulation of the hepatitis C virus life-cycle in engineered murine cell lines. Virology. 444(1-2):1-11. PMID: 23777661
Kapoor A, Simmonds P, Gerold G, Qaisar N, Jain K, Henriquez JA, Firth C, Hirschberg DL, Rice CM, Shields S, Lipkin WI. (2011) Characterization of a canine homolog of hepatitis C virus. PNAS. 108(28):11608-13. PMCID: PMC3136326
Gerold G, Rice CM. (2011) Locking out hepatitis C. Nature Medicine.17(5):542-4. PMID: 21546968
Gerold G, Rice CM, Ploss A. (2010) Teaching new tricks to an old foe: murinizing hepatitis C virus. Hepatology. 52(6):2233-6. PMC4509484
Gerold G, Abu Ajaj K, Bienert M, Laws HJ, Zychlinsky A, de Diego JL. (2008) A Toll-like receptor 2–integrin beta3 complex senses bacterial lipopeptides via vitronectin. Nature Immunology. 9(7):761-8. PMID: 18516040
Gerold G, Zychlinsky A, de Diego JL. (2007) What is the role of Toll-like receptors in bacterial infections? Semin Immunol. 19(1):41-7. PMID: 17280841
de Diego JL, Gerold G, Zychlinsky A. (2007) Sensing, presenting, and regulating PAMPs. Ernst Schering Found Symp Proc. 3:83-95. PMID: 18510100
Loll B*, Gerold G*, Slowik D, Voelter W, Jung C, Saenger W, Irrgang KD. (2005) Thermostability and Ca2+ binding properties of wild type and heterologously expressed PsbO protein from cyanobacterial photosystem II. Biochemistry. 44(12):4691-8. * these authors contributed equally. PMID: 15779895