Publikationen

Publikationen

Eine vollständige Publikationsliste unserer Wissenschaftler

    2024

    • Krueger J, Preusse M, Oswaldo Gomez N, Frommeyer YN, Doberenz S, Lorenz A, Kordes A, Grobe S, Musken M, Depledge DP, Svensson SL, Weiss S, Kaever V, Pich A, Sharma CM, Ignatova Z, Haussler S (2024) tRNA epitranscriptome determines pathogenicity of the opportunistic pathogen Pseudomonas aeruginosa. Proc Natl Acad Sci U S A 121(11): e2312874121.

    • Gömer A, Dinkelborg K, Klöhn M, Jagst M, Wißing MH, Frericks N, Nörenberg P, Behrendt P, Cornberg M, Wedemeyer H, Steinmann E, Maasoumy B, Todt D (2024) Dynamic evolution of the sofosbuvir-associated variant A1343V in HEV-infected patients under concomitant sofosbuvir-ribavirin treatment. JHEP Rep 6(3): 100989.

    • Costa B, Becker J, Krammer T, Mulenge F, Duran V, Pavlou A, Gern OL, Chu X, Li Y, Cicin-Sain L, Eiz-Vesper B, Messerle M, Dölken L, Saliba AE, Erhard F, Kalinke U (2024) Human cytomegalovirus exploits STING signaling and counteracts IFN/ISG induction to facilitate infection of dendritic cells. Nat Commun 15(1): 1745.

    • Haid S, Matthaei A, Winkler M, Sake SM, Gunesch AP, Milke V, Köhler NM, Rückert J, Vieyres G, Kühl D, Nguyen TT, Göhl M, Lasswitz L, Zapatero-Belinchón FJ, Brogden G, Gerold G, Wiegmann B, Bilitewski U, Brown RJP, Brönstrup M, Schulz TF, Pietschmann T (2024) Repurposing screen identifies novel candidates for broad-spectrum coronavirus antivirals and druggable host targets. Antimicrob Agents Chemother 68(3): e0121023.

    • Sake SM, Zhang X, Rajak MK, Urbanek-Quaing M, Carpentier A, Gunesch AP, Grethe C, Matthaei A, Rückert J, Galloux M, Larcher T, Le Goffic R, Hontonnou F, Chatterjee AK, Johnson K, Morwood K, Rox K, Elgaher WAM, Huang J, Wetzke M, Hansen G, Fischer N, F EleouetJ, Rameix-Welti MA, Hirsch AKH, Herold E, Empting M, Lauber C, Schulz TF, Krey T, Haid S, Pietschmann T (2024) Drug repurposing screen identifies lonafarnib as respiratory syncytial virus fusion protein inhibitor. Nat Commun 15(1): 1173.

    • Passos V, Henkel LM, Wang J, Zapatero‐Belinchón FJ, Möller R, Sun G, Waltl I, Schneider T, Wachs A, Ritter B, Kropp KA, Zhu S, Deleidi M, Kalinke U, Schulz TF, Höglinger G, Gerold G, Wegner F, Viejo‐Borbolla A (2024) Innate immune response to SARS‐CoV‐2 infection contributes to neuronal damage in human iPSC‐derived peripheral neurons. J Med Virol 96(2).

    • D'Amato R, Taxiarchi C, Galardini M, Trusso A, Minuz RL, Grilli S, Somerville AGT, Shittu D, Khalil AS, Galizi R, Crisanti A, Simoni A, Müller R (2024) Anti-CRISPR Anopheles mosquitoes inhibit gene drive spread under challenging behavioural conditions in large cages. Nat Commun 15(1): 952.

    • Matthaei A, Joecks S, Frauenstein A, Bruening J, Bankwitz D, Friesland M, Gerold G, Vieyres G, Kaderali L, Meissner F, Pietschmann T (2024) Landscape of protein-protein interactions during hepatitis C virus assembly and release. Microbiol Spectr 12(2): e0256222.

    • Chiyyeadu A, Asgedom G, Bruhn M, Rocha C, Schlegel TU, Neumann T, Galla M, Barbosa PV, Hoffmann M, Ehrhardt K, Ha TC, Morgan M, Schoeder CT, Pöhlmann S, Kalinke U, Schambach A (2024) A tetravalent bispecific antibody outperforms the combination of its parental antibodies and neutralizes diverse SARS-CoV-2 variants. Clin Immunol 260(n/a): 109902.

    • Manoharan J, Rana R, Kuenze G, Gupta D, Elwakiel A, Ambreen S, Wang H, Banerjee K, Zimmermann S, Singh K, Gupta A, Fatima S, Kretschmer S, Schaefer L, Zeng-Brouwers J, Schwab C, Al-Dabet MM, Gadi I, Altmann H, Koch T, Poitz DM, Baber R, Kohli S, Shahzad K, Geffers R, Lee-Kirsch MA, Kalinke U, Meiler J, Mackman N, Isermann B (2024) Tissue factor binds to and inhibits interferon-α receptor 1 signaling. Immunity 57(1): 68-85 e11.

    • Stankov MV, Hoffmann M, Gutierrez Jauregui R, Cossmann A, Morillas Ramos G, Graalmann T, Winter EJ, Friedrichsen M, Ravens I, Ilievska T, Ristenpart J, Schimrock A, Willenzon S, Ahrenstorf G, Witte T, Forster R, Kempf A, Pohlmann S, Hammerschmidt SI, Dopfer-Jablonka A, Behrens GMN (2024) Humoral and cellular immune responses following BNT162b2 XBB.1.5 vaccination. Lancet Infect Dis 24(1): e1-e3.

    • Bruhn M, Obara M, Chiyyeadu A, Costa B, Salam A, Ziegler A, Waltl I, Pavlou A, Bonifacius A, Hoffmann M, Graalmann T, Pöhlmann S, Eiz-Vesper B, Schambach A, Kalinke U (2024) Memory B cells anticipate SARS-CoV-2 variants through somatic hypermutation. J Infect 88(1): 171-187 e14.

    in press

    • Dirr L, Cleeves S, Ramón Roth I, Li L, Fiebig T, Ve T, Häussler S, Braun A, von Itzstein M, Führing JI (in press) Tetramerization is essential for the enzymatic function of the Pseudomonas aeruginosa virulence factor UDP-glucose pyrophosphorylase. mBio n/a(n/a): e0211423.

    • Andreasen MR, Rick T, Alexandersen NR, Hansen KH, Pedersen MS, Warweitzky JK, Botelho CM, Häussler S, Jelsbak L, Schønning K (in press) Identification of a CTX-M-255 β-lactamase containing a G239S substitution selectively conferring resistance to penicillin/β-lactamase inhibitor combinations. J Antimicrob Chemother n/a(n/a): n/a.

    • Frericks N, Brown RJP, Reinecke BM, Herrmann M, Brüggemann Y, Todt D, Miskey C, Vondran FWR, Steinmann E, Pietschmann T, Sheldon J (in press) Unraveling the dynamics of hepatitis C virus adaptive mutations and their impact on antiviral responses in primary human hepatocytes. J Virol n/a(n/a): e0192123.

    • Pink I, Hennigs JK, Ruhl L, Sauer A, Boblitz L, Huwe M, Fuge J, Falk CS, Pietschmann T, de Zwaan M, Prasse A, Kluge S, Klose H, Hoeper MM, Welte T (in press) Blood T cell phenotypes correlate with fatigue severity in post-acute sequelae of COVID-19. Infection n/a(n/a): n/a.

    • Weber A, Neffe L, Diaz LAP, Thoma N, Aghdassi SJS, Denkel LA, Maechler F, Behnke M, Häussler S, Gastmeier P, Kola A (in press) Analysis of transmission-related third-generation cephalosporin-resistant Enterobacterales by electronic data mining and core genome multi-locus sequence typing. J Hosp Infect 140(n/a): 96-101.

    • Vieyres G, Pietschmann T (in press) The role of human lipoproteins for hepatitis C virus persistence. Curr Opin Virol 60(n/a): 101327.

    2023

    • Aghebatrafat AA, Lauber C, Merkel K, Fruth B, Langergraber K, Robbins MM, Wittig RM, Leendertz FH, Calvignac-Spencer S (2023) Evolutionary Insight into the Association between New Jersey Polyomavirus and Humans. Viruses 15(11): 2248.

    • Akmatov MK, Beisheeva NJ, Nurmatov AZ, Gulsunai SJ, Saikal KN, Derkenbaeva AA, Abdrahmanova ZO, Prokein J, Klopp N, Illig T, Kasymov OT, Nurmatov ZS, Pessler F (2023) The Changing Epidemiology of Viral Hepatitis in a Post-Soviet Country-The Case of Kyrgyzstan. Pathogens 12(8): 989.

    • Al-Mekhlafi A, Waqas FH, Krueger M, Klawonn F, Akmatov MK, Muller-Vahl K, Trebst C, Skripuletz T, Stangel M, Suhs KW, Pessler F (2023) Elevated phospholipids and acylcarnitines C4 and C5 in cerebrospinal fluid distinguish viral CNS infections from autoimmune neuroinflammation. J Transl Med 21(1): 776.

    • Alpers K, Vatareck E, Gröbe L, Müsken M, Scharfe M, Häussler S, Tomasch J (2023) Transcriptome Dynamics of Pseudomonas aeruginosa during Transition from Overlapping To Non-Overlapping Cell Cycles. mSystems 8(2): e0113022.

    • Atschekzei F, Fedchenko M, Elsayed A, Dubrowinskaja N, Graalmann T, Ringshausen FC, Witte T, Sogkas G (2023) Rituximab to treat prolidase deficiency due to a novel pathogenic copy number variation in PEPD. RMD Open 9(4).

    • Barends M, Koller N, Scholz C, Duran V, Bosnjak B, Becker J, Doring M, Blees H, Forster R, Kalinke U, Tampe R (2023) Dynamic interactome of the MHC I peptide loading complex in human dendritic cells. Proc Natl Acad Sci U S A 120(25): e2219790120.

    • Behrendt P, Gouttenoire J (2023) Editorial in Hepatology Urine: A place where HEV cannot hide!. Hepatology 77(5): 1475-1477.

    • Buhler M, Li D, Li L, Runft S, Waltl I, Pavlou A, Kalinke U, Ciurkiewicz M, Huehn J, Floess S, Beineke A, Baumgartner W, Gerhauser I (2023) IFNAR signaling of neuroectodermal cells is essential for the survival of C57BL/6 mice infected with Theiler's murine encephalomyelitis virus. J Neuroinflammation 20(1): 58.

    • Burgaya J, Marin J, Royer G, Condamine B, Gachet B, Clermont O, Jaureguy F, Burdet C, Lefort A, de Lastours V, Denamur E, Galardini M, Blanquart F, groups Colibafi/Septicoli&Coliville (2023) The bacterial genetic determinants of Escherichia coli capacity to cause bloodstream infections in humans. PLOS Genet 19(8): 1-28.

    • Camarao AAR, Gern OL, Stegmann F, Mulenge F, Costa B, Saremi B, Jung K, Lepenies B, Kalinke U, Steffen I (2023) Secreted NS1 proteins of tick-borne encephalitis virus and West Nile virus block dendritic cell activation and effector functions. Microbiol Spectr 11(5): e0219223.

    • Carriqui-Madronal B, Lasswitz L, von Hahn T, Gerold G (2023) Genetic and pharmacological perturbation of hepatitis-C virus entry. Curr Opin Virol 62(n/a): 101362.

    • Carriquí-Madroñal B, Sheldon J, Duven M, Stegmann C, Cirksena K, Wyler E, Zapatero-Belinchón FJ, Vondran FlorianWR, Gerold G (2023) The matrix metalloproteinase ADAM10 supports hepatitis C virus entry and cell-to-cell spread via its sheddase activity. PLoS Pathog 19(11): 1-24.

    • Chen F, Yalcin I, Zhao M, Chen C, Blankenfeldt W, Pessler F, Büssow K (2023) Amino acid positions near the active site determine the reduced activity of human ACOD1 compared to murine ACOD1. Sci Rep 13(1): 10360.

    • Chong LC, Lauber C (2023) Viroid-like RNA-dependent RNA polymerase-encoding ambiviruses are abundant in complex fungi. Front Micobiol 14(n/a): 1144003.

    • Dinkelborg K, Kahlhöfer J, Dörge P, Yurdaydin C, Hardtke S, Caruntu FA, Curescu MG, Yalcin K, Akarca US, Gürel S, Zeuzem S, Erhardt A, Lüth S, Papatheodoridis GV, Keskin O, Port K, Radu M, Celen MK, Idilman R, Weber K, Stift J, Wittkop U, Heidrich B, Mederacke I, von der Leyen H, Dienes HP, Cornberg M, Koch A, Manns MP, Wedemeyer H, Deterding K (2023) Quality-of-life scores improve after 96 weeks of PEG-IFNa-2a treatment of hepatitis D: An analysis of the HIDIT-II trial. Liver Int 43(8): 1663-1676.

    • Doherty HM, Kritikos G, Galardini M, Banzhaf M, Moradigaravand D (2023) ChemGAPP: a tool for chemical genomics analysis and phenotypic profiling. Bioinformatics 39(4).

    • Fernandez Villalobos NV, Kessel B, Torres Paez JC, Strömpl J, Kerrinnes T, de la Hoz Restrepo FP, Strengert M, Krause G (2023) Seroprevalence of Hepatitis E virus in children and adolescents living in urban Bogota: An explorative cross-sectional study. Front Public Health 11(n/a): 981172.

    • Fernandez Villalobos NV, Marsall P, Torres Paez JC, Strompl J, Gruber J, Lotto Batista M, Pohl D, Concha G, Frickmann H, de la Hoz Restrepo FP, Schneiderhan-Marra N, Krause G, Dulovic A, Strengert M, Kann S (2023) Humoral immune response to SARS-CoV-2 and endemic coronaviruses in urban and indigenous children in Colombia. Commun Med (Lond) 3(1): 151.

    • Fneish Z, Becker J, Mulenge F, Costa B, Krajewski L, Duran V, Ziegler A, Sommer V, Traidl-Hoffmann C, Gilles S, Kalinke U (2023) Birch pollen extract enhances human cytomegalovirus replication in monocyte-derived dendritic cells. Allergy 78(2): 543-546.

    • Gömer A, Klöhn M, Jagst Michelle, Nocke Maximilian, Pischke Sven, Horvatits T, zur Wiesch JS, Müller T, Hardtke S, Cornberg M, Wedemeyer H, Behrendt P, Steinmann E, Todt D (2023) Emergence of resistance-associated variants during sofosbuvir treatment in chronically infected hepatitis E patients. Hepatology 78(6): 1882-1895.

    • Göttig L, Weiss C, Stubbe M, Hanrieder L, Hofmann S, Grodziecki A, Stadler D, Carpentier A, Protzer U, Schreiner S (2023) Apobec3A Deamination Functions Are Involved in Antagonizing Efficient Human Adenovirus Replication and Gene Expression. mBio 14(3): e0347822.

    • Gür M, Erdmann J, Will A, Liang Z, Andersen JB, Tolker-Nielsen T, Häussler S (2023) Challenges in using transcriptome data to study the c-di-GMP signaling network in Pseudomonas aeruginosa clinical isolates. FEMS Microbes 4(n/a): xtad012.

    • Harit K, Bhattacharjee R, Matuschewski K, Becker J, Kalinke U, Schlüter D, Nishanth G (2023) The deubiquitinating enzyme OTUD7b protects dendritic cells from TNF-induced apoptosis by stabilizing the E3 ligase TRAF2. Cell Death Dis 14(7).

    • Hassenstein MJ, Pischon T, Karch A, Peters A, Kerrinnes T, Teismann H, Schneider A, Thierry S, Moreno Velasquez I, Janke J, Kemmling Y, Castell S (2023) Seropositivity of Borrelia burgdorferi s.l. in Germany---an analysis across four German National Cohort (NAKO) study sites. Sci Rep 13(1): 21087.

    • Hofmann S, Plank V, Groitl P, Skvorc N, Hofmann K, Luther J, Ko C, Zimmerman P, Bruss V, Stadler D, Carpentier A, Rezk S, Nassal M, Protzer U, Schreiner S (2023) SUMO Modification of Hepatitis B Virus Core Mediates Nuclear Entry, Promyelocytic Leukemia Nuclear Body Association, and Efficient Formation of Covalently Closed Circular DNA. Microbiol Spectr 11(3): e0044623.

    • Junker D, Becker M, Wagner TR, Kaiser PD, Maier S, Grimm TM, Griesbaum J, Marsall P, Gruber J, Traenkle B, Heinzel C, Pinilla YT, Held J, Fendel R, Kreidenweiss A, Nelde A, Maringer Y, Schroeder S, Walz JS, Althaus K, Uzun G, Mikus M, Bakchoul T, Schenke-Layland K, Bunk S, Haeberle H, Gopel S, Bitzer M, Renk H, Remppis J, Engel C, Franz AR, Harries M, Kessel B, Lange B, Strengert M, Krause G, Zeck A, Rothbauer U, Dulovic A, Schneiderhan-Marra N (2023) Antibody binding and ACE2 binding inhibition is significantly reduced for both the BA1 and BA2 omicron variants. Clin Infect Dis 76(3): e240-e249.

    • Keller L, Oueis E, Kaur A, Safaei N, Kirsch SH, Gunesch AP, Haid S, Rand U, Cicin-Sain L, Fu C, Wink J, Pietschmann T, Müller R (2023) Persicamidines- Unprecedented Sesquarterpenoids with Potent Antiviral Bioactivity against Coronaviruses. Angew Chem Int Ed Engl 62(6): e202214595.

    • Kettlitz R, Harries M, Ortmann J, Krause G, Mu SpadTeam, Aigner A, Lange B (2023) Association of known SARS-CoV-2 serostatus and adherence to personal protection measures and the impact of personal protective measures on seropositivity in a population-based cross-sectional study (MuSPAD) in Germany. BMC Public Health 23(1): 2281.

    • Kinast V, Andreica I, Ahrenstorf G, Gömer A, Elsner C, Schlienkamp S, Schrader JA, Klöhn M, Ulrich RG, Broering R, Vondran FWR, Todt D, Behrendt P, Dittmer U, Hamprecht A, Witte T, Baraliakos X, Steinmann E (2023) Janus kinase-inhibition modulates hepatitis E virus infection. Antiviral Res 217(n/a): 105690.

    • Lange F, Garn J, Anagho HA, Vondran FWR, von Hahn T, Pietschmann T, Carpentier A (2023) Hepatitis D virus infection, innate immune response and antiviral treatments in stem cell-derived hepatocytes. Liver Int 43(10): 2116-2129.

    • Liang TJ, Law JLM, Pietschmann T, Ray SC, Bukh J, Bull R, Chung RT, Tyrrell DL, Houghton M, Rice CM (2023) Challenge Inoculum for Hepatitis C Virus Controlled Human Infection Model. Clinical Infectious Diseases 77(Supplement 3): S257-S261.

    • Meister TL, Friesland M, Frericks N, Wetzke M, Haid S, Steinmann J, Todt D, Pietschmann T, Steinmann E (2023) Virucidal activity of oral, hand and surface disinfectants against respiratory syncytial virus. J Hosp Infect 141(n/a): 25-32.

    • Merkert S, Haase A, Dahlmann J, Göhring G, Waqas FH, Pessler F, Martin U, Olmer R (2023) Generation of two human NRF2 knockout iPSC clones using CRISPR/Cas9 editing. Stem Cell Res 69(n/a): 103090.

    • Meumann N, Cabanes-Creus M, Ertelt M, Navarro RG, Lucifora J, Yuan Q, Nien-Huber K, Abdelrahman A, Vu XK, Zhang L, Franke AC, Schmithals C, Piiper A, Vogt A, Gonzalez-Carmona M, Frueh JT, Ullrich E, Meuleman P, Talbot SR, Odenthal M, Ott M, Seifried E, Schoeder CT, Schwable J, Lisowski L, Buning H (2023) Novel Adeno-Associated Virus (AAV) Serotype 2 Capsid Variants for Improved Liver-Directed Gene Therapy. Hepatology 77(3): 802-815.

    • Mhlekude B, Postmus D, Stenzel S, Weiner, J 3rd, Jansen J, Zapatero-Belinchon FJ, Olmer R, Richter A, Heinze J, Heinemann N, Muhlemann B, Schroeder S, Jones TC, Muller MA, Drosten C, Pich A, Thiel V, Martin U, Niemeyer D, Gerold G, Beule D, Goffinet C (2023) Pharmacological inhibition of bromodomain and extra-terminal proteins induces an NRF-2-mediated antiviral state that is subverted by SARS-CoV-2 infection. PLoS Pathog 19(9): e1011657.

    • Misiakou MA, Hertz FB, Schonning K, Häussler S, Nielsen KL (2023) Emergence of linezolid-resistant Enterococcus faecium in a tertiary hospital in Copenhagen. Microb Genom 9(7).

    • Nielsen KarenL, Sorensen M, Hertz FB, Misiakou MA, Hasman H, Häussler S, Helleberg M, Schonning K (2023) Within-patient horizontal transfer of pOXA-48 from a hypervirulent Klebsiella pneumoniae SL218 to Serratia marcescens following spread of the K. pneumoniae isolate among hospitalised patients, Denmark, 2021. Euro Surveill 28(17).

    • Pankratz D, Gomez NO, Nielsen A, Mustafayeva A, Gur M, Arce-Rodriguez F, Nielsen PI, Haussler S, Arce-Rodriguez A (2023) An expanded CRISPR-Cas9-assisted recombineering toolkit for engineering genetically intractable Pseudomonas aeruginosa isolates. Nat Protoc 18(11): 3253-3288.

    • Pisciotta A, Sampino AM, Presentato A, Galardini M, Manteca A, Alduina R (2023) The DNA cytosine methylome revealed two methylation motifs in the upstream regions of genes related to morphological and physiological differentiation in Streptomyces coelicolor A(3)2 M145. Sci Rep 13(1): 7038.

    • Rahim MI, Waqas SF, Lienenklaus S, Willbold E, Eisenburger M, Stiesch M (2023) Effect of titanium implants along with silver ions and tetracycline on type I interferon-beta expression during implant-related infections in co-culture and mouse model. Front Bioeng Biotechnol 11(n/a): 1227148.

    • Royer G, Clermont O, Marin J, Condamine B, Dion S, Blanquart F, Galardini M, Denamur E (2023) Epistatic interactions between the high pathogenicity island and other iron uptake systems shape Escherichia coli extra-intestinal virulence. Nat Commun 14(1): 3667.

    • Schrader JA, Burkard TL, Brüggemann Y, Gömer A, Meister TL, Fu RM, Mehnert AK, Thi VLD, Behrendt P, Durantel D, Broering R, Vondran FWR, Todt D, Kinast V, Steinmann E (2023) Epidermal growth factor receptor modulates hepatitis e virus entry in human hepatocytes -HEP-22-1113. Hepatology 77(6): 2104-2117.

    • Schröder LJ, Mulenge F, Pavlou A, Skripuletz T, Stangel M, Gudi V, Kalinke U (2023) Dynamics of reactive astrocytes fosters tissue regeneration after cuprizone-induced demyelination. Glia 71(11): 2573-2590.

    • Sommer H, Djamalova D, Galardini M (2023) Reduced ambiguity and improved interpretability of bacterial genome-wide associations using gene-cluster-centric k-mers. Microb Genom 9(11).

    • Stahl Y, Kabar I, Heinzow H, Maasoumy B, Bremer B, Wedemeyer H, Schmidt HHJ, Pietschmann T, Schlevogt B, Behrendt P (2023) Enhanced Monitoring and Detection of Recent Genotype 3 Hepatitis E Virus Infection through Urine Antigen Testing. Emerg Microbes Infect 12(2): 2251598.

    • Tang X, Xue D, Zhang T, Nilsson-Payant BE, Carrau L, Duan X, Gordillo M, Tan AY, Qiu Y, Xiang J, Schwartz RE, tenOever BR, Evans T, Chen S (2023) A multi-organoid platform identifies CIART as a key factor for SARS-CoV-2 infection. Nat Cell Biol 25(3): 381-389.

    • Tergast TL, Schulte B, Griemsmann M, Kahlhöfer J, Dörge P, Hinrichs JB, Kraft ARM, Schmidt JJ, Behrendt P, Wedemeyer H, Cornberg M, Maasoumy B (2023) Application of CT contrast medium is not associated with an increased risk for acute kidney injury in patients with decompensated cirrhosis. Aliment Pharmacol Ther 57(1): 136-145.

    • Tischer-Zimmermann S, Bonifacius A, Santamorena MM, Mausberg P, Stoll S, Döring M, Kalinke U, Blasczyk R, Maecker-Kolhoff B, Eiz-Vesper B (2023) Reinforcement of cell-mediated immunity driven by tumor-associated Epstein-Barr virus (EBV)-specific T cells during targeted B-cell therapy with rituximab. Front Immunol 14(n/a): 878953.

    • Waqas FH, Shehata M, Elgaher WAM, Lacour A, Kurmasheva N, Begnini F, Kiib AE, Dahlmann J, Chen C, Pavlou A, Poulsen TB, Merkert S, Martin U, Olmer R, Olagnier D, Hirsch AKH, Pleschka S, Pessler F (2023) NRF2 activators inhibit influenza A virus replication by interfering with nucleo-cytoplasmic export of viral RNPs in an NRF2-independent manner. PLOS Pathogens 19(7): 1-24.

    • Yang Q, Elz AE, Panis M, Liu T, Nilsson-Payant BE, Blanco-Melo D (2023) Modulation of Influenza A virus NS1 expression reveals prioritization of host response antagonism at single-cell resolution. Front Microbiol 14(n/a): 1267078.

    • Zhang Y, Kinast V, Sheldon J, Frericks N, Todt D, Zimmer M, Caliskan N, Brown RJP, Steinmann E, Pietschmann T (2023) Mouse Liver-Expressed Shiftless Is an Evolutionarily Conserved Antiviral Effector Restricting Human and Murine Hepaciviruses. Microbiol Spectr 11(4): e0128423.

    2022

    • Alejo-Valle O, Weigert K, Bhayadia R, Ng M, Issa H, Beyer C, Emmrich S, Schuschel K, Ihling C, Sinz A, Zimmermann M, Wickenhauser C, Flasinski M, Regenyi E, Labuhn M, Reinhardt D, Yaspo ML, Heckl D, Klusmann JH (2022) The megakaryocytic transcription factor ARID3A suppresses leukemia pathogenesis. Blood 139(5): 651-665.

    • Arce-Rodriguez A, Pankratz D, Preusse M, Nikel PI, Häussler S (2022) Dual Effect: High NADH Levels Contribute to Efflux-Mediated Antibiotic Resistance but Drive Lethality Mediated by Reactive Oxygen Species. mBio 13(1): e0243421.

    • Arshad H, Siokis A, Franke R, Habib A, Alfonso JCL, Poliakova Y, Lücke E, Michaelis K, Brönstrup M, Meyer-Hermann M, Bilitewski U, Vila J, Abel L, Illig T, Schreiber J, Pessler F (2022) Reprogramming of Amino Acid Metabolism Differs between Community-Acquired Pneumonia and Infection-Associated Exacerbation of Chronic Obstructive Pulmonary Disease. Cells 11(15): 2283.

    • Badenhorst M, de Heus P, Auer A, Tegtmeyer B, Stang A, Dimmel K, Tichy A, Kubacki J, Bachofen C, Steinmann E, Cavalleri JMV (2022) Active equine parvovirus-hepatitis infection is most frequently detected in Austrian horses of advanced age. Equine Vet J 54(2): 379-389.

    • Bader CD, Panter F, Garcia R, Tchesnokov EP, Haid S, Walt C, Spröer C, Kiefer AF, Götte M, Overmann J, Pietschmann T, Müller R (2022) Sandacrabins - Structurally Unique Antiviral RNA Polymerase Inhibitors from a Rare Myxobacterium. Chemistry 28(10): e202104484.

    • Baier C, Huang J, Reumann K, Indenbirken D, Thol F, Koenecke C, Ebadi E, Heim A, Bange FC, Haid S, Pietschmann T, Fischer N (2022) Target capture sequencing reveals a monoclonal outbreak of respiratory syncytial virus B infections among adult hematologic patients. Antimicrob Resist Infect Control 11(1): 88.

    • Bankwitz D, Krey T, Pietschmann T (2022) Entwicklungsansätze für Impfstoffe gegen Hepatitis-C-Virus-Infektionen. Bundesgesundheitsblatt - Gesundheitsforschung - Gesundheitsschutz 65(2): 183-191.

    • Becker J, Kalinke U (2022) Toll-like receptors matter: plasmacytoid dendritic cells in COVID-19. EMBO J 41(10): e111208.

    • Becker M, Cossmann Anne, Lurken K, Junker D, Gruber J, Juengling J, Ramos GM, Beigel A, Wrenger E, Lonnemann G, Stankov MV, Dopfer-Jablonka A, Kaiser PD, Traenkle B, Rothbauer U, Krause Gerard, Schneiderhan-Marra N, Strengert M, Dulovic A, Behrens GMN (2022) Longitudinal cellular and humoral immune responses after triple BNT162b2 and fourth full-dose mRNA-1273 vaccination in haemodialysis patients. Front Immunol 13(n/a): 1004045.

    • Behrendt P, Friesland M, Wißmann JE, Kinast V, Stahl Y, Praditya D, Hueffner L, Nörenberg PM, Bremer B, Maasoumy B, Steinmann J, Becker B, Paulmann D, Brill FHH, Steinmann J, Ulrich RG, Brüggemann Y, Wedemeyer H, Todt D, Steinmann E (2022) Hepatitis E virus is highly resistant to alcohol-based disinfectants. J Hepatol 76(5): 1062-1069.

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    • Haack PA, Harmrolfs K, Bader CD, Garcia R, Gunesch AP, Haid S, Popoff A, Voltz A, Kim H, Bartenschlager R, Pietschmann T, Müller R (2022) Thiamyxins: Structure and Biosynthesis of Myxobacterial RNA-Virus Inhibitors. Angew Chem Int Ed Engl 61(52): e202212946.

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    • Knop L, Spanier J, Larsen PK, Witte A, Bank U, Dunay IR, Kalinke U, Schüler T (2022) IFNAR signaling in fibroblastic reticular cells can modulate CD8(+) memory fate decision. Eur J Immunol 52(6): 895-906.

    • Koller N, Hollthaler P, Barends M, Doring M, Spahn C, Duran V, Costa B, Becker J, Heilemann M, Kalinke U, Tampe R (2022) Nanoscale organization of the MHC I peptide-loading complex in human dendritic cells. Cell Mol Life Sci 79(9): 477.

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    • Lauber C, Gerl MJ, Klose C, Ottosson F, Melander O, Simons K (2022) Lipidomic risk scores are independent of polygenic risk scores and can predict incidence of diabetes and cardiovascular disease in a large population cohort. PLoS Biol 20(3): 1-23.

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    • Meister TL, Arroyo LG, Shanahan R, Papapetrou MA, Reinecke B, Brüggemann Y, Todt D, Stang A, Hazlett M, Baird JD, Steinmann E (2022) Infection of young foals with Equine Parvovirus-Hepatitis following a fatal non-biologic case of Theiler's disease. Vet Microbiol 274(n/a): 109557.

    • Messaoudi O, Steinmann E, Praditya D, Bendahou M, Wink J (2022) Taxonomic Characterization, Antiviral Activity and Induction of Three New Kenalactams in Nocardiopsis sp. CG3. Curr Microbiol 79(9): 284.

    • Meumann N, Schmithals C, Elenschneider L, Hansen T, Balakrishnan A, Hu Q, Hook S, Schmitz J, Bräsen JH, Franke AC, Olarewaju O, Brandenberger C, Talbot SR, Fangmann J, Hacker UT, Odenthal M, Ott M, Piiper A, Büning H (2022) Hepatocellular Carcinoma Is a Natural Target for Adeno-Associated Virus (AAV) 2 Vectors. Cancers 14(2): 427.

    • Michaely LM, Schuwerk L, Allnoch L, Schön K, Waltl I, Larsen PK, Pavlou A, Prajeeth CK, Rimmelzwaan GF, Becker SC, Kalinke U, Baumgärtner W, Gerhauser I (2022) Intact Type I Interferon Receptor Signaling Prevents Hepatocellular Necrosis but Not Encephalitis in a Dose-Dependent Manner in Rift Valley Fever Virus Infected Mice. Int J Mol Sci 23(20): 12492.

    • Mulkern AJ, Oyama LB, Cookson AR, Creevey CJ, Wilkinson TJ, Olleik H, Maresca M, da Silva GC, Fontes PP, Bazzolli DMS, Mantovani HC, Damaris BF, Mur LAJ, Huws SA (2022) Microbiome-derived antimicrobial peptides offer therapeutic solutions for the treatment of Pseudomonas aeruginosa infections. NPJ Biofilms Microbiomes 8(1): 70.

    • Neffe L, Abendroth L, Bautsch W, Häussler S, Tomasch J (2022) High plasmidome diversity of extended-spectrum beta-lactam-resistant Escherichia coli isolates collected during one year in one community hospital. Genomics 114(3): 110368.

    • Pais TF, Ali H, Moreira da Silva J, Duarte N, Neres R, Chhatbar C, Acurcio RC, Guedes RC, Strano Moraes MC, Costa-Silva B, Kalinke U, Penha-Goncalves C (2022) Brain endothelial STING1 activation by Plasmodium-sequestered heme promotes cerebral malaria via type I IFN response. Proc Natl Acad Sci U S A 119(36): e2206327119.

    • Paulsen M, Scharff AZ, de Cassan K, Sugianto RI, Blume C, Blume H, Christmann M, Hauss C, Illig T, Jonczyk R, Klopp N, Kopfnagel V, Lichtinghagen R, Lucas H, Luhr A, Mutschler F, Pietschmann T, Pott PC, Prokein J, Schaefer P, Stahl F, Stanislawski N, von der Born J, Schmidt BMW, Heiden S, Stiesch M, Memaran N, Melk A (2022) Children and Adolescents' Behavioral Patterns in Response to Escalating COVID-19 Restriction Reveal Sex and Age Differences. Journal of Adolescent Health 70(3): 378-386.

    • Reinecke B, Frericks N, Lauber C, Dinkelborg K, Matthaei A, Vondran FWR, Behrendt P, Haid S, Brown RJP, Pietschmann T (2022) The Human Liver-Expressed Lectin CD302 Restricts Hepatitis C Virus Infection. J Virol 96(7): e0199521.

    • Riccardi C, Innocenti G, Fondi M, Bacci G (2022) Fast, Ungapped Reads Mapping Using Squid. Int J Environ Res Public Health 19(9): 5442.

    • Riese P, Trittel S, Akmatov MK, May M, Prokein J, Illig T, Schindler C, Sawitzki B, Elfaki Y, Floess S, Huehn J, Blazejewski AJ, Strowig T, Hernandez-Vargas EA, Geffers R, Zhang B, Li Y, Pessler F, Guzmàn CA (2022) Distinct immunological and molecular signatures underpinning influenza vaccine responsiveness in the elderly. Nat Commun 13(1): 6894.

    • Rosendal E, Mihai IS, Becker M, Das D, Frangsmyr L, Persson BD, Rankin GD, Groning R, Trygg J, Forsell M, Ankarklev J, Blomberg A, Henriksson J, Overby AK, Lenman A (2022) Serine Protease Inhibitors Restrict Host Susceptibility to SARS-CoV-2 Infections. mBio 13(3): e0089222.

    • Rovai A, Chung B, Hu Q, Hook S, Yuan Q, Kempf T, Schmidt F, Grimm D, Talbot SR, Steinbruck L, Gotting J, Bohne J, Krooss SA, Ott M (2022) In vivo adenine base editing reverts C282Y and improves iron metabolism in hemochromatosis mice. Nat Commun 13(1): 5215.

    • Sake SM, Kosch C, Blockus S, Haid S, Gunesch AP, Zhang X, Friesland M, Trummer SB, Grethe C, Kühnel A, Rückert J, Duprex WP, Huang J, Rameix-Welti MA, Empting M, Fischer N, Hirsch AKH, Schulz TF, Pietschmann T (2022) Respiratory Syncytial Virus Two-Step Infection Screen Reveals Inhibitors of Early and Late Life Cycle Stages. Antimicrob Agents Chemother 66(12): e0103222.

    • Schuhenn J, Meister TL, Todt D, Bracht T, Schork K, Billaud JN, Elsner C, Heinen N, Karakoese Z, Haid S, Kumar S, Brunotte L, Eisenacher M, Di Y, Lew J, Falzarano D, Chen J, Yuan Z, Pietschmann T, Wiegmann B, Uebner H, Taube C, Le-Trilling VTK, Trilling M, Krawczyk A, Ludwig S, Sitek B, Steinmann E, Dittmer U, Lavender KJ, Sutter K, Pfaender S (2022) Differential interferon-alpha subtype induced immune signatures are associated with suppression of SARS-CoV-2 infection. Proc Natl Acad Sci U S A 119(8).

    • Schwerk J, Kemper L, Bussey KA, Lienenklaus S, Weiss S, Cicin-Sain L, Kröger A, Kalinke U, Collins CM, Speck SH, Messerle M, Wirth D, Brinkmann MM, Hauser H, Köster M (2022) Type I Interferon Signaling Controls Gammaherpesvirus Latency In Vivo. Pathogens 11(12): 1554.

    • Sohail A, Iqbal AA, Sahini N, Chen F, Tantawy M, Waqas F, Winterhoff M, Ebensen T, Schultz K, Geffers R, Schughart K, Preusse M, Shehata M, Bähre H, Pils MC, Guzman CA, Mostafa A, Pleschka S, Falk C, Michelucci A, Pessler F (2022) Itaconate and derivatives reduce interferon responses and inflammation in influenza A virus infection. PLOS Pathog 18(1): 1-40.

    • Taubert R, Engel B, Diestelhorst J, Hupa-Breier KL, Behrendt P, Baerlecken NT, Sühs KW, Janik MK, Zachou K, Sebode M, Schramm C, Londono MC, Habes S, Oo YH, Lalanne C, Pape S, Schubert M, Hust M, Dübel S, Thevis M, Jonigk D, Beimdiek J, Buettner FFR, Drenth JPH, Muratori L, Adams DH, Dyson JK, Renand A, Graupera I, Lohse AW, Dalekos GN, Milkiewicz P, Stangel M, Maasoumy B, Witte T, Wedemeyer H, Manns MP, Jaeckel E (2022) Quantification of polyreactive immunoglobulin G facilitates the diagnosis of autoimmune hepatitis. Hepatology 75(1): 13-27.

    • Thoming JG, Haussler S (2022) Transcriptional Profiling of Pseudomonas aeruginosa Infections. Adv Exp Med Biol 1386(n/a): 303-323.

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    • Umutesi J, Nsanzimana S, Yingkai Liu C, Vanella P, Ott JJ, Krause G (2022) Long-term effect of chronic hepatitis B on mortality in HIV-infected persons in a differential HBV transmission setting. BMC Infect Dis 22(1): 500.

    • Waltl Inken, Kalinke Ulrich (2022) Beneficial and detrimental functions of microglia during viral encephalitis. Trends Neurosci 45(2): 158-170.

    • Wang G, Brunel JM, Preusse M, Mozaheb N, Willger SD, Larrouy-Maumus G, Baatsen P, Häussler S, Bolla JM, van Bambeke F (2022) The membrane-active polyaminoisoprenyl compound NV716 re-sensitizes Pseudomonas aeruginosa to antibiotics and reduces bacterial virulence. Commun Biol 5(1): 871.

    • Waqas SF, Sohail A, Nguyen AHH, Usman A, Ludwig T, Wegner A, Malik MNH, Schuchardt S, Geffers R, Winterhoff M, Merkert S, Martin U, Olmer R, Lachmann N, Pessler F (2022) ISG15 deficiency features a complex cellular phenotype that responds to treatment with itaconate and derivatives. Clin Transl Med 12(7): e931.

    • Weber T, Potthoff J, Bizu S, Labuhn M, Dold L, Schoofs T, Horning M, Ercanoglu MS, Kreer C, Gieselmann L, Vanshylla K, Langhans B, Janicki H, Ströh LJ, Knops E, Nierhoff D, Spengler U, Kaiser R, Bjorkman PJ, Krey T, Bankwitz D, Pfeifer N, Pietschmann T, Flyak AI, Klein F (2022) Analysis of antibodies from HCV elite neutralizers identifies genetic determinants of broad neutralization. Immunity 55(2): 341-354.e7.

    • Wetzke M, Funken D, Lange M, Bejo L, Haid S, Monteiro JGT, Schutz K, Happle C, Schulz TF, Seidenberg J, Pietschmann T, Hansen G (2022) IRIS: Infection with RespIratory Syncytial Virus in infants-a prospective observational cohort study. BMC Pulm Med 22(1): 88.

    • Yang X, Ali S, Zhao M, Richter L, Schäfer V, Schliehe-Diecks J, Frank M, Qi J, Larsen PK, Skerra J, Islam H, Wachtmeister T, Alter C, Huang A, Bhatia S, Köhrer K, Kirschning C, Weighardt H, Kalinke U, Kalscheuer R, Uhrberg M, Scheu S (2022) The Mycotoxin Beauvericin Exhibits Immunostimulatory Effects on Dendritic Cells via Activating the TLR4 Signaling Pathway. Front Immunol 13(n/a): 856230.

    2021

    • Adamek M, Davies J, Beck A, Jordan L, Becker AM, Mojzesz M, Rakus K, Rumiac T, Collet B, Brogden G, Way K, Bergmann SM, Zou J, Steinhagen D (2021) Antiviral Actions of 25-Hydroxycholesterol in Fish Vary With the Virus-Host Combination. Front Immunol 12(n/a): 581786.

    • Al-Mekhlafi A, Sühs KW, Schuchardt S, Kuhn M, Müller-Vahl K, Trebst C, Skripuletz T, Klawonn F, Stangel M, Pessler F (2021) Elevated Free Phosphatidylcholine Levels in Cerebrospinal Fluid Distinguish Bacterial from Viral CNS Infections. Cells 10(5): 1115.

    • Arnberg N, Lenman A (2021) Special Issue “Adenovirus Pathogenesis”. Viruses 13(6): 1112.

    • Bankwitz D, Bahai A, Labuhn M, Doepke M, Ginkel C, Khera T, Todt D, Stroh LJ, Dold L, Klein F, Klawonn F, Krey T, Behrendt P, Cornberg M, McHardy AC, Pietschmann T (2021) Hepatitis C reference viruses highlight potent antibody responses and diverse viral functional interactions with neutralising antibodies. Gut 70(9): 1734-1745.

    • Beck J, Seitz S, Lauber C, Nassal M (2021) Conservation of the HBV RNA element epsilon in nackednaviruses reveals ancient origin of protein-primed reverse transcription. Proc Natl Acad Sci U S A 118(13).

    • Becker M, Dulovic A, Junker D, Ruetalo N, Kaiser PD, Pinilla YT, Heinzel C, Haering J, Traenkle B, Wagner TR, Layer M, Mehrlaender M, Mirakaj V, Held J, Planatscher H, Schenke-Layland K, Krause G, Strengert M, Bakchoul T, Althaus K, Fendel R, Kreidenweiss A, Koeppen M, Rothbauer U, Schindler M, Schneiderhan-Marra N (2021) Immune response to SARS-CoV-2 variants of concern in vaccinated individuals. Nat Commun 12(1): 3109.

    • Becker M, Strengert M, Junker D, Kaiser PD, Kerrinnes T, Traenkle B, Dinter H, Haring J, Ghozzi S, Zeck A, Weise F, Peter A, Horber S, Fink S, Ruoff F, Dulovic A, Bakchoul T, Baillot A, Lohse S, Cornberg M, Illig T, Gottlieb J, Smola S, Karch A, Berger K, Rammensee HG, Schenke-Layland K, Nelde A, Marklin M, Heitmann JS, Walz JS, Templin M, Joos TO, Rothbauer U, Krause G, Schneiderhan-Marra N (2021) Exploring beyond clinical routine SARS-CoV-2 serology using MultiCoV-Ab to evaluate endemic coronavirus cross-reactivity. Nat Commun 12(1): 1152.

    • Behrendt P, Bremer B, Todt D, Steinmann E, Manns MP, Cornberg M, Wedemeyer H, Maasoumy B (2021) Significant compartment-specific impact of different RNA extraction methods and PCR assays on the sensitivity of hepatitis E virus detection. Liver Int 41(8): 1815-1823.

    • Bosnjak B, Odak I, Ritter C, Stahl K, Graalmann T, Steinbrück L, Blasczyk R, Falk CS, Schulz TF, Wedemeyer HH, Cornberg M, Ganser A, Förster R, Koenecke C (2021) Case Report: Convalescent Plasma Therapy Induced Anti-SARS-CoV-2 T Cell Expansion, NK Cell Maturation and Virus Clearance in a B Cell Deficient Patient After CD19 CAR T Cell Therapy. Front Immunol 12(n/a): 721738.

    • Concha G, Frickmann H, Oey A, Strengert M, Kreienbrock L, Kann S (2021) Direct and Indirect Proof of SARS-CoV-2 Infections in Indigenous Wiwa Communities in North-Eastern Colombia-A Cross-Sectional Assessment Providing Preliminary Surveillance Data. Vaccines 9(10): 1120.

    • Dong TN, Brogden G, Gerold G, Khosla M (2021) A multitask transfer learning framework for the prediction of virus-human protein-protein interactions. BMC Bioinformatics 22(1): 572.

    • Duran V, Grabski E, Hozsa C, Becker J, Yasar H, Monteiro JT, Costa B, Koller N, Lueder Y, Wiegmann B, Brandes G, Kaever V, Lehr CM, Lepenies B, Tampe R, Förster R, Bosnjak B, Furch M, Graalmann T, Kalinke U (2021) Fucosylated lipid nanocarriers loaded with antibiotics efficiently inhibit mycobacterial propagation in human myeloid cells. J Control Release 334(n/a): 201-212.

    • Faisal MR, Kellermann MY, Rohde S, Putra MY, Murniasih T, Risdian C, Mohr KI, Wink J, Praditya DF, Steinmann E, Köck M, Schupp PJ (2021) Ecological and Pharmacological Activities of Polybrominated Diphenyl Ethers (PBDEs) from the Indonesian Marine Sponge Lamellodysidea herbacea. Mar Drugs 19(11): 611.

    • Fernandez Villalobos NV, Ott JJ, Klett-Tammen CJ, Bockey A, Vanella P, Krause G, Lange B (2021) Effect modification of the association between comorbidities and severe course of COVID-19 disease by age of study participants: a systematic review and meta-analysis. Syst Rev 10(1): 194.

    • Fink S, Ruoff F, Stahl A, Becker M, Kaiser P, Traenkle B, Junker D, Weise F, Ruetalo N, Hörber S, Peter A, Nelde A, Walz J, Krause G, Baillot A, Schenke-Layland K, Joos TO, Rothbauer U, Schneiderhan-Marra N, Schindler M, Templin MF (2021) Multiplexed Serum Antibody Screening Platform Using Virus Extracts from Endemic Coronaviridae and SARS-CoV-2. ACS Infect Dis 7(6): 1596-1606.

    • Fraguas-Eggenschwiler M, Eggenschwiler R, Sollner JH, Cortnumme L, Vondran FWR, Cantz T, Ott M, Niemann H (2021) Direct conversion of porcine primary fibroblasts into hepatocyte-like cells. Sci Rep 11(1): 9334.

    • Franke R, Overwin H, Häussler S, Brönstrup M (2021) Targeting Bacterial Gyrase with Cystobactamid, Fluoroquinolone, and Aminocoumarin Antibiotics Induces Distinct Molecular Signatures in Pseudomonas aeruginosa. mSystems 6(4): e0061021.

    • Franz S, Pott F, Zillinger T, Schuler C, Dapa S, Fischer C, Passos V, Stenzel S, Chen F, Dohner K, Hartmann G, Sodeik B, Pessler F, Simmons G, Drexler JF, Goffinet C (2021) Human IFITM3 restricts chikungunya virus and Mayaro virus infection and is susceptible to virus-mediated counteraction. Life Sci Alliance 4(7).

    • Gern OL, Mulenge F, Pavlou A, Ghita L, Steffen I, Stangel M, Kalinke U (2021) Toll-like Receptors in Viral Encephalitis. Viruses 13(10): 2065.

    • Ghita L, Breitkopf V, Mulenge F, Pavlou A, Gern OL, Durán V, Prajeeth CK, Kohls M, Jung K, Stangel M, Steffen I, Kalinke U (2021) Sequential MAVS and MyD88/TRIF signaling triggers anti-viral responses of tick-borne encephalitis virus-infected murine astrocytes. J Neurosci Res 99(10): 2478-2492.

    • Ghita L, Spanier J, Chhatbar C, Mulenge F, Pavlou A, Larsen PK, Waltl I, Lueder Y, Kohls M, Jung K, Best SM, Forster R, Stangel M, Schreiner D, Kalinke U (2021) MyD88 signaling by neurons induces chemokines that recruit protective leukocytes to the virus-infected CNS. Sci Immunol 6(60).

    • Glebe D, Goldmann N, Lauber C, Seitz S (2021) HBV evolution and genetic variability: Impact on prevention, treatment and development of antivirals. Antiviral Res 186(n/a): 104973.

    • Graalmann T, Borst K, Manchanda H, Vaas L, Bruhn M, Graalmann L, Koster M, Verboom M, Hallensleben M, Guzman CA, Sutter G, Schmidt RE, Witte T, Kalinke U (2021) B cell depletion impairs vaccination-induced CD8(+) T cell responses in a type I interferon-dependent manner. Ann Rheum Dis 80(12): 1537-1544.

    • Grekov I, Thöming JG, Kordes A, Häussler S (2021) Evolution of Pseudomonas aeruginosa toward higher fitness under standard laboratory conditions. ISME J 15(4): 1165-1177.

    • Grischke J, Szafranski SP, Muthukumarasamy U, Haeussler S, Stiesch M (2021) Removable denture is a risk indicator for peri-implantitis and facilitates expansion of specific periodontopathogens: a cross-sectional study. BMC Oral Health 21(1): 173.

    • Gussarow D, Bonifacius A, Cossmann A, Stankov MV, Mausberg P, Tischer-Zimmermann S, Gödecke N, Kalinke U, Behrens GMN, Blasczyk R, Eiz-Vesper B (2021) Long-Lasting Immunity Against SARS-CoV-2: Dream or Reality?. Front Med 8(n/a).

    • Haag S, Häussler S (2021) Quo vadis clinical diagnostic microbiology?. Clin Microbiol Infect 27(11): 1562-1564.

    • Hartmann R, Jeckel H, Jelli E, Singh PK, Vaidya S, Bayer M, Rode DKH, Vidakovic L, Diaz-Pascual F, Fong JCN, Dragos A, Lamprecht O, Thöming JG, Netter N, Häussler S, Nadell CD, Sourjik V, Kovacs AT, Yildiz FH, Drescher K (2021) Quantitative image analysis of microbial communities with BiofilmQ. Nat Microbiol 6(2): 151-156.

    • Iampietro M, Dumont C, Mathieu C, Spanier J, Robert J, Charpenay A, Dupichaud S, Dhondt KP, Aurine N, Pelissier R, Ferren M, Mely S, Gerlier D, Kalinke U, Horvat B (2021) Activation of cGAS/STING pathway upon paramyxovirus infection. iScience 24(6): 102519.

    • Jo WK, Schadenhofer A, Habierski A, Kaiser FK, Saletti G, Ganzenmueller T, Hage E, Haid S, Pietschmann T, Hansen G, Schulz TF, Rimmelzwaan GF, Osterhaus Adme, Ludlow M. (2021) Reverse genetics systems for contemporary isolates of respiratory syncytial virus enable rapid evaluation of antibody escape mutants. Proc Natl Acad Sci U S A 118(14).

    • Kaszab E, Rado J, Kriszt B, Paszti J, Lesinszki V, Szabo A, Toth G, Khaledi A, Szoboszlay S (2021) Groundwater, soil and compost, as possible sources of virulent and antibiotic-resistant Pseudomonas aeruginosa. Int J Environ Health Res 31(7): 848-860.

    • Kirui J, Abidine Y, Lenman A, Islam K, Gwon YD, Lasswitz L, Evander M, Bally M, Gerold G (2021) The Phosphatidylserine Receptor TIM-1 Enhances Authentic Chikungunya Virus Cell Entry. Cells 10(7): 1828.

    • Komoll RM, Hu Q, Olarewaju O, von Döhlen L, Yuan Q, Xie Y, Tsay HC, Daon J, Qin R, Manns MP, Sharma AD, Goga A, Ott M, Balakrishnan A (2021) MicroRNA-342-3p is a potent tumour suppressor in hepatocellular carcinoma. J Hepatol 74(1): 122-134.

    • Kreissl S, Hendler S, Akmatov MK, von Meien M, Range U, Pessler F, Vogelberg C (2021) Reduced exhaled breath condensate pH and severity of allergic sensitization predict school age asthma. J Allergy Clin Immunol Pract 9(4): 1570-1577.

    • Krenn V, Bosone C, Burkard TR, Spanier J, Kalinke U, Calistri A, Salata C, Christoff RR, Garcez PP, Mirazimi A, Knoblich JA (2021) Organoid modeling of Zika and herpes simplex virus 1 infections reveals virus-specific responses leading to microcephaly. Cell Stem Cell 28(8): 1362-1379 e1367.

    • Krüger N, Rocha C, Runft S, Krüger J, Färber I, Armando F, Leitzen E, Brogden G, Gerold G, Pöhlmann S, Hoffmann M, Baumgärtner W (2021) The Upper Respiratory Tract of Felids Is Highly Susceptible to SARS-CoV-2 Infection. Int J Mol Sci 22(19): 10636.

    • Lohrmann F, Berg A, Wicker E, Imm A, Krause G, Zürn K, Berner R, Hufnagel M, Lander F (2021) Prevalence of Capsular Serotype, Pilus Island Distribution, and Antibiotic Resistance in Pediatric and Adult Invasive Group B Streptococcus Isolates. Pediatr Infect Dis J 40(1): 76-82.

    • Luo Y, Möhn N, Skripuletz T, Senel M, Tumani H, Pessler F, Sühs KW, Stangel M (2021) Differentiation of viral and autoimmune central nervous system inflammation by kynurenine pathway. Ann Clin Transl Neurol 8(12): 2228-2234.

    • Malik MNH, Waqas SFH, Zeitvogel J, Cheng J, Geffers R, Gouda ZAE, Elsaman AM, Radwan AR, Schefzyk M, Braubach P, Auber B, Olmer R, Müsken M, Roesner LM, Gerold G, Schuchardt S, Merkert S, Martin U, Meissner F, Werfel T, Pessler F (2021) Congenital deficiency reveals critical role of ISG15 in skin homeostasis. J Clin Invest 39(3): 276-280.

    • Mhlekude B, Lenman A, Sidoyi P, Joseph J, Kruppa J, Businge CB, Mdaka ML, Konietschke F, Pich A, Gerold G, Goffinet C, Mall AS (2021) The barrier functions of crude cervical mucus plugs against HIV-1 infection in the context of cell-free and cell-to-cell transmission. AIDS 35(13): 2105-2117.

    • Mulas F, Wang X, Song S, Nishanth G, Yi W, Brunn A, Larsen PK, Isermann B, Kalinke U, Barragan A, Naumann M, Deckert M, Schluter D (2021) The deubiquitinase OTUB1 augments NF-kappaB-dependent immune responses in dendritic cells in infection and inflammation by stabilizing UBC13. Cell Mol Immunol 18(6): 1512-1527.

    • Nelde A, Bilich T, Heitmann JS, Maringer Y, Salih HR, Roerden M, Lübke M, Bauer J, Rieth J, Wacker M, Peter A, Hörber S, Traenkle B, Kaiser PD, Rothbauer U, Becker M, Junker D, Krause G, Strengert M, Schneiderhan-Marra N, Templin MF, Joos TO, Kowalewski DJ, Stos-Zweifel V, Fehr M, Rabsteyn A, Mirakaj V, Karbach J, Jäger E, Graf M, Gruber LC, Rachfalski D, Preuß B, Hagelstein I, Märklin M, Bakchoul T, Gouttefangeas C, Kohlbacher O, Klein R, Stevanovi S, Rammensee HG, Walz JS (2021) SARS-CoV-2-derived peptides define heterologous and COVID-19-induced T cell recognition. Nat Immunol 22(1): 74-85.

    • Nicolay W, Moeller R, Kahl S, Vondran F, Pietschmann T, Kunz S, Gerold G (2021) Characterization of RNA Sensing Pathways in Hepatoma Cell Lines and Primary Human Hepatocytes. Cells 10(11): 3019.

    • Pezoldt J, Wiechers C, Erhard F, Rand U, Bulat T, Beckstette M, Brendolan A, Huehn J, Kalinke U, Mueller M, Strobl B, Deplancke B, Cicin-Sain L, Sitnik KM (2021) Single-cell transcriptional profiling of splenic fibroblasts reveals subset-specific innate immune signatures in homeostasis and during viral infection. Commun Biol 4(12): 1355.

    • Prior S, Metcalfe C, Hufton SE, Wadhwa M, Schneider CK, Burns C (2021) Maintaining `standards' for biosimilar monoclonal antibodies. Nat Biotechnol 39(3): 276-280.

    • Rafie K, Lenman A, Fuchs J, Rajan A, Arnberg N, Carlson LA (2021) The structure of enteric human adenovirus 41-A leading cause of diarrhea in children. Sci Adv 7(2).

    • Rajan A, Palm E, Trulsson F, Mundigl S, Becker M, Persson BD, Frängsmyr L, Lenman A (2021) Heparan Sulfate Is a Cellular Receptor for Enteric Human Adenoviruses. Viruses 13(2): 298.

    • Ramli SR, Bunk B, Spröer C, Geffers R, Jarek M, Bhuju S, Goris M, Mustakim S, Pessler F (2021) Complete Genome Sequencing of Leptospira interrogans Isolates from Malaysia Reveals Massive Genome Rearrangement but High Conservation of Virulence-Associated Genes. Pathogens 10(9): 1198.

    • Reinecke B, Klöhn M, Brüggemann Y, Kinast V, Todt D, Stang A, Badenhorst M, Koeppel K, Guthrie A, Groner U, Puff C, de le Roi M, Baumgärtner W, Cavalleri JMV, Steinmann E (2021) Clinical Course of Infection and Cross-Species Detection of Equine Parvovirus-Hepatitis. Viruses 13(8): 1454.

    • Ricke-Hoch M, Stelling E, Lasswitz L, Gunesch AP, Kasten M, Zapatero-Belinchón FJ, Brogden G, Gerold G, Pietschmann T, Montiel V, Balligand JL, Facciotti F, Hirsch E, Gausepohl T, Elbahesh H, Rimmelzwaan GF, Höfer A, Kühnel MP, Jonigk D, Eigendorf J, Tegtbur U, Mink L, Scherr M, Illig T, Schambach A, Pfeffer TJ, Hilfiker A, Haverich A, Hilfiker-Kleiner D (2021) Impaired immune response mediated by prostaglandin E2 promotes severe COVID-19 disease. PLOS ONE 16(8): 1-24.

    • Risso-Ballester J, Galloux M, Cao J, Goffic RL, Hontonnou F, Jobart-Malfait A, Desquesnes A, Sake SM, Haid S, Du M, Zhang X, Zhang H, Wang Z, Rincheval V, Zhang Y, Pietschmann T, Eleouët JF, Rameix-Welti MA, Altmeyer R (2021) A condensate-hardening drug blocks RSV replication in vivo. Nature 595(7868): 596-599.

    • Schinner S, Preusse M, Kesthely C, Häussler S (2021) Analysis of the organization and expression patterns of the convergent Pseudomonas aeruginosa lasR/rsaL gene pair uncovers mutual influence. Mol Microbiol 115(4): 643-657.

    • Strengert M, Becker M, Ramos GM, Dulovic A, Gruber J, Juengling J, Lürken K, Beigel A, Wrenger E, Lonnemann G, Cossmann A, Stankov MV, Dopfer-Jablonka A, Kaiser PD, Traenkle B, Rothbauer U, Krause G, Schneiderhan-Marra N, Behrens GMN (2021) Cellular and humoral immunogenicity of a SARS-CoV-2 mRNA vaccine in patients on haemodialysis. EBioMedicine 70(n/a): 103524.

    • Tegtmeyer B, Vieyres G, Todt D, Lauber C, Ginkel C, Engelmann M, Herrmann M, Pfaller CK, Vondran FWR, Broering R, Vafadarnejad E, Saliba AE, Puff C, Baumgartner W, Miskey C, Ivics Z, Steinmann E, Pietschmann T, Brown RJP (2021) Initial HCV infection of adult hepatocytes triggers a temporally structured transcriptional program containing diverse pro- and anti-viral elements. J Virol 95(10): e00245-21.

    • Wagner TR, Ostertag E, Kaiser PD, Gramlich M, Ruetalo N, Junker D, Haering J, Traenkle B, Becker M, Dulovic A, Schweizer H, Nueske S, Scholz A, Zeck A, Schenke-Layland K, Nelde A, Strengert M, Walz JS, Zocher G, Stehle T, Schindler M, Schneiderhan-Marra N, Rothbauer U (2021) NeutrobodyPlex-monitoring SARS-CoV-2 neutralizing immune responses using nanobodies. EMBO Rep 22(5): e52325.

    • Wibowo JT, Kellermann MY, Köck M, Putra MY, Murniasih T, Mohr KI, Wink J, Praditya DF, Steinmann E, Schupp PJ (2021) Anti-Infective and Antiviral Activity of Valinomycin and Its Analogues from a Sea Cucumber-Associated Bacterium, Streptomyces sp. SV 21. Mar Drugs 19(2): 81.

    • Winterhoff M, Chen F, Sahini N, Ebensen T, Kuhn M, Kaever V, Bähre H, Pessler F (2021) Establishment, Validation, and Initial Application of a Sensitive LC-MS/MS Assay for Quantification of the Naturally Occurring Isomers Itaconate, Mesaconate, and Citraconate. Metabolites 11(5): 270.

    • Yang T, Poenisch M, Khanal R, Hu Q, Dai Z, Li R, Song G, Yuan Q, Yao Q, Shen X, Taubert R, Engel B, Jaeckel E, Vogel A, Falk CS, Schambach A, Gerovska D, Arauzo-Bravo MJ, Vondran FWR, Cantz T, Horscroft N, Balakrishnan A, Chevessier F, Ott M, Sharma AD (2021) Therapeutic HNF4A mRNA attenuates liver fibrosis in a preclinical model. J Hepatol 75(6): 1420-1433.

    • Zapatero-Belinchchon FJ, Ötjengerdes R, Sheldon J, Schulte B, Carriqui-Madronal B, Brogden G, Arroyo-Fernandez LM, Vondran FWR, Maasoumy B, von Hahn T, Gerold G (2021) Interdependent Impact of Lipoprotein Receptors and Lipid-Lowering Drugs on HCV Infectivity. Cells 10(7): 1626.

    • Zapatero-Belinchon FJ, Moeller R, Lasswitz L, van Ham M, Becker M, Brogden G, Rosendal E, Bi W, Carriqui-Madronal B, Islam K, Lenman A, Gunesch AP, Kirui J, Pietschmann T, Överby AK, Jänsch L, Gerold G (2021) Fluvastatin mitigates SARS-CoV-2 infection in human lung cells. iScience 24(12): 103469.

    • Zapatero-Belinchón FranciscoJosé, Carriqu\'ı-Madroñal Belén, Gerold Gisa (2021) Proximity labeling approaches to study protein complexes during virus infection. 109(n/a): 63-104.

    • de Araujo LS, Ribeiro-Alves M, Wipperman MF, Vorkas CK, Pessler F, Saad MHF (2021) Transcriptomic Biomarkers for Tuberculosis: Validation of NPC2 as a Single mRNA Biomarker to Diagnose TB, Predict Disease Progression, and Monitor Treatment Response. Cells 10(10): 2704.

    2020

    • Alberione MP, Moeller R, Kirui J, Ginkel C, Doepke M, Stroh LJ, Machtens JP, Pietschmann T, Gerold G (2020) Single-nucleotide variants in human CD81 influence hepatitis C virus infection of hepatoma cells. Med Microbiol Immunol 209(4): 499-514.

    • Armando F, Gambini M, Corradi A, Becker K, Marek K, Pfankuche VM, Mergani AE, Brogden G, Buhr N, Köckritz-Blickwede M, Naim HY, Baumgärtner W, Puff C (2020) Mesenchymal to epithelial transition driven by canine distemper virus infection of canine histiocytic sarcoma cells contributes to a reduced cell motility in vitro. J Cell Mol Med 24(16): 9332-9348.

    • Baird J, Tegtmeyer B, Arroyo L, Stang A, Brüggemann Y, Hazlett M, Steinmann E (2020) The association of Equine Parvovirus-Hepatitis (EqPV-H) with cases of non-biologic-associated Theiler's disease on a farm in Ontario, Canada. Vet Microbiol 242(n/a): 108575.

    • Behrens GMN, Cossmann A, Stankov MV, Schulte B, Streeck H, Förster R, Bosnjak B, Willenzon S, Boeck AL, Thu Tran A, Thiele T, Graalmann T, Kayser MZ, Zychlinsky Scharff A, Dopfer C, Horke A, Pink I, Witte T, Wetzke M, Ernst D, Jablonka A, Happle C (2020) Strategic Anti-SARS-CoV-2 Serology Testing in a Low Prevalence Setting: The COVID-19 Contact (CoCo) Study in Healthcare Professionals. Infect Dis Ther 9(4): 837-849.

    • Blockus S, Sake SM, Wetzke M, Grethe C, Graalmann T, Pils M, Goffic RL, Galloux M, Prochnow H, Rox K, Hüttel S, Rupcic Z, Wiegmann B, Dijkman R, Rameix-Welti MA, Eleouet JF, Duprex WP, Thiel V, Hansen G, Brönstrup M, Haid S, Pietschmann T (2020) Labyrinthopeptins as virolytic inhibitors of respiratory syncytial virus cell entry. Antiviral Res 177(n/a): 104774.

    • Bohm K, Strompl J, Krumbholz A, Zell R, Krause G, Sievers C (2020) Establishment of a highly sensitive assay for detection of Hepatitis E virus-specific immunoglobulins. J Clin Microbiol 58(2).

    • Borst K, Flindt S, Blank P, Larsen PK, Chhatbar C, Skerra J, Spanier J, Hirche C, König M, Alanentalo T, Hafner M, Waibler Z, Pfeffer K, Sexl V, Sutter G, Müller W, Graalmann T, Kalinke U (2020) Selective reconstitution of IFN‑γ gene function in Ncr1+ NK cells is sufficient to control systemic vaccinia virus infection. PLOS Pathog 16(2): 1-19.

    • Brown RJP, Tegtmeyer B, Sheldon J, Khera T, Anggakusuma, Todt D, Vieyres G, Weller R, Joecks S, Zhang Y, Sake S, Bankwitz D, Welsch K, Ginkel C, Engelmann M, Gerold G, Steinmann E, Yuan Q, Ott M, Vondran FWR, Krey T, Stroh LJ, Miskey C, Ivics Z, Herder V, Baumgartner W, Lauber C, Seifert M, Tarr AW, McClure CP, Randall G, Baktash Y, Ploss A, Thi VLD, Michailidis E, Saeed M, Verhoye L, Meuleman P, Goedecke N, Wirth D, Rice CM, Pietschmann T (2020) Liver-expressed Cd302 and Cr1l limit hepatitis C virus cross-species transmission to mice. Sci Adv 6(45).

    • Brown RJP, Tegtmeyer B, Sheldon J, Khera T, Anggakusuma, Todt D, Vieyres G, Weller R, Joecks S, Zhang Y, Sake S, Bankwitz D, Welsch K, Ginkel C, Engelmann M, Gerold G, Steinmann E, Yuan Q, Ott M, Vondran FWR, Krey T, Stroh LJ, Miskey C, Ivics Z, Herder V, Baumgartner W, Lauber C, Seifert M, Tarr AW, McClure CP, Randall G, Baktash Y, Ploss A, Thi VLD, Michailidis E, Saeed M, Verhoye L, Meuleman P, Goedecke N, Wirth D, Rice CM, Pietschmann T (2020) Liver-expressed Cd302 and Cr1l limit hepatitis C virus cross-species transmission to mice. Sci Adv 6(45).

    • Carpentier A, Sheldon J, Vondran FWR, Brown RJ, Pietschmann T (2020) Efficient acute and chronic infection of stem cell-derived hepatocytes by hepatitis C virus. Gut 69(9): 1659-1666.

    • Dai Z, Ott M, Sharma AD (2020) Equal opportunity offer for all hepatocytes. J Hepatol 73(1): 6-8.

    • Dai Z, Song G, Balakrishnan A, Yang T, Yuan Q, Moebus S, Weiss AC, Bentler M, Zhu J, Shen X, Bantel H, Jaeckel E, Kispert A, Vogel A, Saborowski A, Buening H, Manns MP, Cantz T, Ott M, Sharma AD (2020) Growth differentiation factor 11 attenuates liver fibrosis via expansion of liver progenitor cells. Gut 69(6): 1004-1115.

    • Depke T, Haussler S, Bronstrup M (2020) The Peptide Chain Release Factor Methyltransferase PrmC Influences the Pseudomonas aeruginosa PA14 Endo- and Exometabolome. Metabolites 10(10).

    • Depke T, Thöming JG, Kordes A, Häussler S, Brönstrup M (2020) Untargeted LC-MS Metabolomics Differentiates Between Virulent and Avirulent Clinical Strains of Pseudomonas aeruginosa. Biomolecules 10(7): 1041.

    • Donnert M, Elsheikh S, Arce-Rodriguez A, Pawar V, Braubach P, Jonigk D, Haverich A, Weiss S, Müsken M, Häussler S (2020) Targeting bioenergetics is key to counteracting the drug-tolerant state of biofilm-grown bacteria. PLoS Pathog 16(12): 1-22.

    • Eismann H, Sieg L, Ahmed H, Teske J, Behrendt P, Friedrich L, Schumacher C, Johanning K (2020) Influence of alcohol consumption on blood coagulation in ROTEM: an in-vivo study. Korean J Anesthesiol 73(4): 334-341.

    • Elsner C, Ponnurangam A, Kazmierski J, Zillinger T, Jansen J, Todt D, Dohner K, Xu S, Ducroux A, Kriedemann N, Malassa A, Larsen PK, Hartmann G, Barchet W, Steinmann E, Kalinke U, Sodeik B, Goffinet C (2020) Absence of cGAS-mediated type I IFN responses in HIV-1-infected T cells. Proc Natl Acad Sci U S A 117(32): 19475-19486.

    • Elsner C, Ponnurangam A, Kazmierski J, Zillinger T, Jansen J, Todt D, Dohner K, Xu S, Ducroux A, Kriedemann N, Malassa A, Larsen PK, Hartmann G, Barchet W, Steinmann E, Kalinke U, Sodeik B, Goffinet C (2020) Absence of cGAS-mediated type I IFN responses in HIV-1-infected T cells. Proc Natl Acad Sci U S A 117(32): 19475-19486.

    • Engelhardt F, Tomasch J, Häussler S (2020) Organism-specific depletion of highly abundant RNA species from bacterial total RNA. Access Microbiol 2(10): acmi000159.

    • Felgner S, Preusse M, Beutling U, Stahnke S, Pawar V, Rohde M, Brönstrup M, Stradal T, Häussler S (2020) Host-induced spermidine production in motile Pseudomonas aeruginosa triggers phagocytic uptake. Elife 9(n/a).

    • Forster D, Schwarz JH, Brosinski K, Kalinke U, Sutter G, Volz A (2020) Obstetric Ultrasonography to Detect Fetal Abnormalities in a Mouse Model for Zika Virus Infection. Viruses 12(1): 72.

    • Freuer D, Linseisen J, Waterboer T, Pessler F, Guzmán CA, Wawro N, Peters A, Meisinger C (2020) Seropositivity of selected chronic infections and different measures of obesity. PLoS One 15(4): 1-16.

    • Gamrekelashvili J, Kapanadze T, Sablotny S, Ratiu C, Dastagir K, Lochner M, Karbach S, Wenzel P, Sitnow A, Fleig S, Sparwasser T, Kalinke U, Holzmann B, Haller H, Limbourg FP (2020) Notch and TLR signaling coordinate monocyte cell fate and inflammation. eLife 9(n/a).

    • Gerold G, Moeller R, Pietschmann T (2020) Hepatitis C Virus Entry: Protein Interactions and Fusion Determinants Governing Productive Hepatocyte Invasion. Cold Spring Harb Perspect Med 10(2): a036830.

    • Glebe D, Goldmann N, Lauber C, Seitz S (2020) HBV evolution and genetic variability: Impact on prevention, treatment and development of antivirals. Antiviral Res 186(n/a): 104973.

    • Gunesch AP, Zapatero-Belinchon FJ, Pinkert L, Steinmann E, Manns MP, Schneider G, Pietschmann T, Bronstrup M, von Hahn T (2020) Filovirus antiviral activity of cationic amphiphilic drugs is associated with lipophilicity and ability to induce phospholipidosis. Antimicrob Agents Chemother 64(8).

    • Haake K, Neehus AL, Buchegger T, Kühnel MP, Blank P, Philipp F, Oleaga-Quintas C, Schulz A, Grimley M, Goethe R, Jonigk D, Kalinke U, Boisson-Dupuis S, Casanova JL, Bustamante J, Lachmann N (2020) Patient iPSC-Derived Macrophages to Study Inborn Errors of the IFN-gamma Responsive Pathway. Cells 9(2): 483.

    • Hahn K, Pollmann L, Nowak J, Nguyen AHH, Haake K, Neehus AL, Waqas SFH, Pessler F, Baumann U, Hetzel M, Casanova JL, Schulz A, Bustamante J, Ackermann M, Lachmann N (2020) Human Lentiviral Gene Therapy Restores the Cellular Phenotype of Autosomal Recessive Complete IFN-gammaR1 Deficiency. Mol Ther Methods Clin Dev 17(n/a): 785-795.

    • Hosseini S, Michaelsen-Preusse K, Grigoryan G, Chhatbar C, Kalinke U, Korte M (2020) Type I Interferon Receptor Signaling in Astrocytes Regulates Hippocampal Synaptic Plasticity and Cognitive Function of the Healthy CNS. Cell Rep 31(7): 107666.

    • Iampietro M, Aurine N, Dhondt KP, Dumont C, Pelissier R, Spanier J, Vallve A, Raoul H, Kalinke U, Horvat B (2020) Control of Nipah Virus infection in mice by the host adaptors mitochondrial antiviral signaling protein (MAVS) and Myeloid differentiation primary response 88 (MyD88). J Infect Dis 221((Supplement_4)): S401-S406.

    • Kamar N, Abravanel F, Behrendt P, Hofmann J, Pageaux GP, Barbet C, Moal V, Couzi L, Horvatits T, Man RADe, Cassuto E, Elsharkawy AM, Riezebos-Brilman A, Scemla A, Hillaire S, Donnelly MC, Radenne S, Sayegh J, Garrouste C, Dumortier J, Glowaki F, Matignon M, Coilly A, Figueres L, Mousson C, Minello A, Dharancy S, Rerolle JP, Lebray P, Etienne I, Perrin P, Choi M, Marion O, Izopet J, Belliere J, Cointault O, Bello ADel, Espostio L, Hebral AL, Lavayssiere L, Lhomme S, Mansuy JM, Wedemeyer H, Nickel P, Bismuth M, Stefic K, Büchler M, D'Alteroche L, Colson P, Bufton S, Ramiere C, Trimoulet P, Pischke S, Todesco E, Soussan RS, Legendre C, Mallet V, Johannessen I, Simpson K (2020) Ribavirin for Hepatitis E virus infection after organ transplantation: A large European retrospective multicenter study. Clin Infect Dis 71(5): 1204-1211.

    • Khaledi A, Weimann A, Schniederjans M, Asgari E, Kuo TH, Oliver A, Cabot G, Kola A, Gastmeier P, Hogardt M, Jonas D, Mofrad MRK, Bremges A, McHardy AC, Häussler S (2020) Predicting antimicrobial resistance in Pseudomonas aeruginosa with machine learning-enabled molecular diagnostics. EMBO Mol Med 12(3): e10264.

    • Kinast V, Plociennikowska A, Anggakusuma, Bracht T, Todt D, Brown RJP, Boldanova T, Zhang Y, Brueggemann Y, Friesland M, Engelmann M, Vieyres G, Broering R, Vondran FWR, Heim MH, Sitek B, Bartenschlager R, Pietschmann T, Steinmann E (2020) C19orf66 is an interferon-induced inhibitor of HCV replication that restricts formation of the viral replication organelle. J Hepatol 73(3): 549-558.

    • Knop L, Deiser K, Bank U, Witte A, Mohr J, Philipsen L, Fehling HJ, Müller AJ, Kalinke U, Schüler T (2020) IL-7 derived from lymph node fibroblastic reticular cells is dispensable for naive T cell homeostasis but crucial for central memory T cell survival. Euro J Immunol 50(6): 846-857.

    • Krooss S, Werwitzke S, Kopp J, Rovai A, Varnholt D, Wachs AS, Goyenvalle A, Aarstma-Rus A, Ott M, Tiede A, Langemeier J, Bohne J (2020) Pathological mechanism and antisense oligonucleotide-mediated rescue of a non-coding variant suppressing factor 9 RNA biogenesis leading to hemophilia B. PLOS Genet 16(4): 1-20.

    • Krooss SA, Dai Z, Schmidt F, Rovai A, Fakhiri J, Dhingra A, Yuan Q, Yang T, Balakrishnan A, Steinbruck L, Srivaratharajan S, Manns MP, Schambach A, Grimm D, Bohne J, Sharma AD, Buning H, Ott M (2020) Ex Vivo/In vivo Gene Editing in Hepatocytes Using Äll-in-One" CRISPR-Adeno-Associated Virus Vectors with a Self-Linearizing Repair Template. iScience 23(1): 100764.

    • Köllmann C, Sake SM, Jones PG, Pietschmann T, Werz DB (2020) Protecting-Group-Mediated Diastereoselective Synthesis of C4'-Methylated Uridine Analogs and Their Activity against the Human Respiratory Syncytial Virus. J Org Chem 85(6): 4267-4278.

    • Lindqvist R, Rosendal E, Weber E, Asghar N, Schreier S, Lenman A, Johansson M, Dobler G, Bestehorn M, Kroger A, Overby AK (2020) The envelope protein of tick-borne encephalitis virus influences neuron entry, pathogenicity, and vaccine protection. J Neuroinflammation 17(1): 284.

    • Luo Y, Möhn N, Al-Mekhlafi A, Schuchardt S, Skripuletz T, Sühs W, Pessler F, Stangel M (2020) Targeted metabolomic profiling of cerebrospinal fluid from patients with progressive multifocal leukoencephalopathy. PLoS One 15(11): 1-10.

    • Markovic J, Sharma AD, Balakrishnan A (2020) MicroRNA-221: A Fine Tuner and Potential Biomarker of Chronic Liver Injury. Cells 9(8): 1767.

    • Martin-Fernandez M, Garcia-Morato MariaBravo, Gruber Conor, Loza SaraMurias, Malik MuhammadNasirHayat, Alsohime Fahad, Alakeel Abdullah, Valdez Rita, Buta Sofija, Buda Guadalupe, Marti MarceloA., Larralde Margarita, Boisson Bertrand, Rodriguez MartaFeito, Qiu Xueer, Chrabieh Maya, Ayed MohammedAl, Muhsen SalehAl, Desai JigarV., Ferre EliseM.N., Rosenzweig SergioD., Amador-Borrero Blanca, Bravo-Gallego LuzYadira, Olmer Ruth, Merkert Sylvia, Bret Montserrat, Sood AmikaK., Al rabiaah Abdulkarim, Temsah MohamadHani, Halwani Rabih, Hernandez Michelle, Pessler Frank, Casanova Jean-Laurent, Bustamante Jacinta, Lionakis MichailS., Bogunovic Dusan (2020) Systemic Type I IFN Inflammation in Human ISG15 Deficiency Leads to Necrotizing Skin Lesions. Cell Rep 31(6): 107633.

    • Merkert S, Jaboreck MC, Engels L, Malik MNH, Göhring G, Pessler F, Martin U, Olmer R (2020) Generation of two human ISG15 knockout iPSC clones using CRISPR/Cas9 editing. Stem Cell Res 50(n/a): 102135.

    • Moreira-Soto A, Arroyo-Murillo F, Sander AL, Rasche A, Corman V, Tegtmeyer B, Steinmann E, Corrales-Aguilar E, Wieseke N, Avey-Arroyo J, Drexler JF (2020) Cross-order host switches of hepatitis C-related viruses illustrated by a novel hepacivirus from sloths. Virus Evol 6(2): veaa033.

    • Moreno H, Rastrojo A, Pryce R, Fedeli C, Zimmer G, Bowden TA, Gerold G, Kunz S (2020) A novel circulating tamiami mammarenavirus shows potential for zoonotic spillover. PLoS Negl Trop Dis 14(12): 1-33.

    • Muthukumarasamy U, Preusse M, Kordes A, Koska M, Schniederjans M, Khaledi A, Häussler S (2020) Single-nucleotide polymorphism-based genetic diversity analysis of clinical Pseudomonas aeruginosa isolates. Genome Biol Evol 12(4): 396-406.

    • Namineni S, O`Connor T, Faure-Dupuy S, Johansen P, Riedl T, Liu K, Xu H, Singh I, Shinde P, Li F, Pandyra A, Sharma P, Ringelhan M, Muschaweckh A, Borst K, Blank P, Lampl S, Durantel D, Farhat R, Weber A, Lenggenhager D, Kündig TM, Staeheli P, Protzer U, Wohlleber D, Holzmann B, Binder M, Breuhahn K, Assmus LM, Nattermann J, Abdullah Z, Rolland M, Dejardin E, Lang PA, Lang KS, Karin M, Lucifora J, Kalinke U, Knolle PA, Heikenwalder M (2020) A dual role for hepatocyte-intrinsic canonical NF-$\upkappa$B signaling in virus control. J Hepatol 72(5): 960-975.

    • Page M, Almond N, Rose NJ, Schneider CK (2020) Diagnostics and the coronavirus: don't let the standards slip. Nat Biotechnol 38(6): 673-674.

    • Palor M, Stejskal L, Mandal P, Lenman A, Alberione MP, Kirui J, Moeller R, Ebner S, Meissner F, Gerold G, Shepherd AJ, Grove J (2020) Cholesterol sensing by CD81 is important for hepatitis C virus entry. J Biol Chem 295(50): 16931-16948.

    • Persson BD, Lenman A, Frangsmyr L, Schmid M, Ahlm C, Pluckthun A, Jenssen H, Arnberg N (2020) Lactoferrin-Hexon Interactions Mediate CAR-Independent Adenovirus Infection of Human Respiratory Cells. J Virol 94(14).

    • Praditya D, Friesland M, Gravemann U, Handke W, Todt D, Behrendt P, Müller TH, Steinmann E, Seltsam A (2020) Hepatitis E virus is effectively inactivated in platelet concentrates by ultraviolet C light. Vox Sang 115(7): 555-561.

    • Prochnow H, Rox K, Birudukota NVS, Weichert L, Hotop SK, Klahn P, Mohr K, Franz S, Banda DH, Blockus S, Schreiber J, Haid S, Oeyen M, Martinez JP, Sussmuth RD, Wink J, Meyerhans A, Goffinet C, Messerle M, Schulz TF, Kroger A, Schols D, Pietschmann T, Bronstrup M (2020) Labyrinthopeptins exert broad-spectrum antiviral activity through lipid-binding-mediated virolysis. J Virol 94(2).

    • Reinke S, Linge M, Diebner HH, Luksch H, Glage S, Gocht A, Robertson AAB, Cooper MA, Hofmann SR, Naumann R, Sarov M, Behrendt R, Roers A, Pessler F, Roesler J, Rösen-Wolff A, Winkler S (2020) Non-canonical Caspase-1 Signaling Drives RIP2-Dependent and TNF-alpha-Mediated Inflammation In Vivo. Cell Rep 30(8): 2501-2511.e5.

    • Samir M, Vidal RO, Abdallah F, Capece V, Seehusen F, Geffers R, Hussein A, Ali AAH, Bonn S, Pessler F (2020) Organ-specific small non-coding RNA responses in domestic (Sudani) ducks experimentally infected with highly pathogenic avian influenza virus (H5N1). RNA Biol 17(1): 112-124.

    • Schaupp L, Muth S, Rogell L, Kofoed-Branzk M, Melchior F, Lienenklaus S, Ganal-Vonarburg SC, Klein M, Guendel F, Hain T, Schütze K, Grundmann U, Schmitt V, Dorsch M, Spanier J, Larsen PK, Schwanz T, Jäckel S, Reinhardt C, Bopp T, Danckwardt S, Mahnke K, Heinz GA, Mashreghi MF, Durek P, Kalinke U, Kretz O, Huber TB, Weiss S, Wilhelm C, Macpherson AJ, Schild H, Diefenbach A, Probst HC (2020) Microbiota-Induced Type I Interferons Instruct a Poised Basal State of Dendritic Cells. Cell 181(5): 1080-1096 e19.

    • Schinner S, Engelhardt F, Preusse M, Thoming JG, Tomasch J, Haussler S (2020) Genetic determinants of Pseudomonas aeruginosa fitness during biofilm growth. Biofilm 2(n/a): 100023.

    • Seelbinder B, Wallstabe J, Marischen L, Weiss E, Wurster S, Page L, Löffler C, Bussemer L, Schmitt AL, Wolf T, Linde J, Cicin-Sain L, Becker J, Kalinke U, Vogel J, Panagiotou G, Einsele H, Westermann AJ, Schäuble S, Loeffler J (2020) Triple RNA-Seq Reveals Synergy in a Human Virus-Fungus Co-infection Model. Cell Rep 33(7): 108389.

    • Seupt A, Schniederjans M, Tomasch J, Haussler S (2020) Expression of the MexXY aminoglycoside efflux pump and presence of an aminoglycoside modifying enzyme in clinical Pseudomonas aeruginosa isolates are highly correlated. Antimicrob Agents Chemother 65(1).

    • Shi X, Liu TT, Yu XN, Balakrishnan A, Zhu HR, Guo HY, Zhang GC, Bilegsaikhan E, Sun JL, Song GQ, Weng SQ, Dong L, Ott M, Zhu JM, Shen XZ (2020) microRNA-93-5p promotes hepatocellular carcinoma progression via a microRNA-93-5p/MAP3K2/c-Jun positive feedback circuit. Oncogene 39(35): 5768-5781.

    • Thöming JG, Tomasch J, Preusse M, Koska M, Grahl N, Pohl S, Willger SD, Kaever V, Müsken M, Häussler S (2020) Parallel evolutionary paths to produce more than one Pseudomonas aeruginosa biofilm phenotype. npj Biofilms and Microbiomes 6(1).

    • Todt D, Friesland M, Moeller N, Praditya D, Kinast V, Bruggemann Y, Knegendorf L, Burkard T, Steinmann J, Burm R, Verhoye L, Wahid A, Meister TL, Engelmann M, Pfankuche VM, Puff C, Vondran FWR, Baumgartner W, Meuleman P, Behrendt P, Steinmann E (2020) Robust hepatitis E virus infection and transcriptional response in human hepatocytes. Proc Natl Acad Sci U S A 117(3): 1731-1741.

    • Tran HTL, Morikawa K, Anggakusuma, Zibi R, Thi VLD, Penin F, Heim MH, Quadroni M, Pietschmann T, Gouttenoire J, Moradpour D (2020) OCIAD1 is a host mitochondrial substrate of the hepatitis C virus NS3-4A protease. PLOS ONE 15(7): 1-18.

    • Vardi A, Ben-Dor S, Cho SM, Kalinke U, Spanier J, Futerman AH (2020) Mice defective in interferon signaling help distinguish between primary and secondary pathological pathways in a mouse model of neuronal forms of Gaucher disease. J Neuroinflammation 17(1): 265.

    • Vermeulen CJ, Xu CJ, Vonk JM, Ten Hacken NHT, Timens W, Heijink IH, Nawijn MC, Boekhoudt J, van Oosterhout AJ, Affleck K, Weckmann M, Koppelman GH, van den Berge M (2020) Differential DNA methylation in bronchial biopsies between persistent asthma and asthma in remission. Eur Respir J 555(2).

    • Vieyres G, Reichert I, Carpentier A, Vondran FWR, Pietschmann T (2020) The ATGL lipase cooperates with ABHD5 to mobilize lipids for hepatitis C virus assembly. PLOS Pathog 16(6): 1-41.

    • Wahlicht T, Vieyres G, Bruns SA, Meumann N, Buning H, Hauser H, Schmitz I, Pietschmann T, Wirth D (2020) Controlled Functional Zonation of Hepatocytes In Vitro by Engineering of Wnt Signaling. ACS Chem Biol 9(7): 1638-1649.

    • Yang D, Dai Z, Yang T, Balakrishnan A, Yuan Q, Vondran FWR, Manns MP, Ott M, Cantz T, Sharma AD (2020) MicroRNA-125b-5p Regulates Hepatocyte Proliferation During the Termination Phase of Liver Regeneration. Hepatol Commun 4(12): 1851-1863.

    • de Araujo LS, Pessler K, Suhs KW, Novoselova N, Klawonn F, Kuhn M, Kaever V, Muller-Vahl K, Trebst C, Skripuletz T, Stangel M, Pessler F (2020) Phosphatidylcholine PC ae C44:6 in cerebrospinal fluid is a sensitive biomarker for bacterial meningitis. J Transl Med 18(1): 9.

    2019

    • Ahmetlic F, Riedel T, Homberg N, Bauer V, Trautwein N, Geishauser A, Sparwasser T, Stevanovic S, Rocken M, Mocikat R (2019) Regulatory T Cells in an Endogenous Mouse Lymphoma Recognize Specific Antigen Peptides and Contribute to Immune Escape. Cancer Immunol Res(7): 4.

    • Akmatov MK, Riese P, Trittel S, May M, Prokein J, Illig T, Schindler C, Guzman CA, Pessler F (2019) Self-reported diabetes and herpes zoster are associated with a weak humoral response to the seasonal influenza A H1N1 vaccine antigen among the elderly. BMC Infect Dis 19(1): 656.

    • Arshad H, Alfonso JCL, Franke R, Michaelis K, Araujo L, Habib A, Zboromyrska Y, Lucke E, Strungaru E, Akmatov MK, Hatzikirou H, Meyer-Hermann M, Petersmann A, Nauck M, Bronstrup M, Bilitewski U, Abel L, Sievers J, Vila J, Illig T, Schreiber J, Pessler F (2019) Decreased plasma phospholipid concentrations and increased acid sphingomyelinase activity are accurate biomarkers for community-acquired pneumonia. J Transl Med 17(1): 365.

    • Badenhorst M, de Heus P, Auer A, Rümenapf T, Tegtmeyer B, Kolodziejek J, Nowotny N, Steinmann E, Cavalleri JMV (2019) No evidence of mosquito involvement in the transmission of equine hepacivirus (Flaviviridae) in an epidemiological survey of Austrian horses. Viruses 11(11): 1014.

    • Banda DH, Perin PM, Brown RJP, Todt D, Solodenko W, Hoffmeyer P, Sahu KK, Houghton M, Meuleman P, Müller R, Kirschning A, Pietschmann T (2019) A central hydrophobic E1 region controls the pH range of hepatitis C virus membrane fusion and susceptibility to fusion inhibitors. J Hepatol 70(6): 1082-1092.

    • Behrendt P, Bruning J, Todt D, Steinmann E (2019) Influence of Tattoo Ink on Hepatitis C Virus Infectiousness. Open Forum Infect Dis 6(3): ofz047.

    • Bolard A, Schniederjans M, Haussler S, Triponney P, Valot B, Plesiat P, Jeannot K (2019) Production of norspermidine contributes to aminoglycoside resistance in pmrAB mutants of Pseudomonas aeruginosa. Antimicrob Agents Chemother 63(10).

    • Borst K, Graalmann T, Kalinke U (2019) Reply to: "Lack of Kupffer cell depletion in diethylnitrosamine-induced hepatic Inflammation". J Hepatol 70(4): 815-816.

    • Borst K, Graalmann T, Kalinke U (2019) Reply to: Unveiling the depletion of Kupffer cells in experimental hepatocarcinogenesis through liver macrophage subtype-specific markers. J Hepatol 71(3): 633-635.

    • Caputo M, Horn J, Karch A, Akmatov MK, Becher H, Braun B, Brenner H, Castell S, Fischer B, Giani G, Gunther K, Hoffmann B, Jockel KH, Keil T, Kluppelholz B, Krist L, Leitzmann MF, Lieb W, Linseisen J, Meisinger C, Moebus S, Obi N, Pischon T, Schipf S, Schmidt B, Sievers C, Steinbrecher A, Volzke H, Mikolajczyk R (2019) Herpes zoster incidence in Germany - an indirect validation study for self-reported disease data from pretest studies of the population-based German National Cohort. BMC Infect Dis 19(1): 19.

    • Chen F, Lukat P, Iqbal AA, Saile K, Kaever V, van den Heuvel J, Blankenfeldt W, Bussow K, Pessler F (2019) Crystal structure of cis-aconitate decarboxylase reveals the impact of naturally occurring human mutations on itaconate synthesis. Proc Natl Acad Sci U S A 116(41): 20644-20654.

    • Chepkirui C, Cheng T, Sum WC, Matasyoh JC, Decock C, Praditya DF, Wittstein K, Steinmann E, Stadler M (2019) Skeletocutins A-L: Antibacterial Agents from the Kenyan Wood-Inhabiting Basidiomycete, Skeletocutis sp.. J Agric Food Chem 67(31): 8468-8475.

    • Costa R, Todt D, Zapatero-Belinchon F, Schenk C, Anastasiou OE, Walker A, Hertel B, Timmer L, Bojkova D, Ruckert M, Sarrazin C, Timm J, Lohmann V, Manns MP, Steinmann E, von Hahn T, Ciesek S (2019) SEC14L2, a lipid-binding protein, regulates HCV replication in culture with inter- and intra-genotype variations. J Hepatol 70(4): 603-614.

    • Domingo E, de Avila AI, Gallego I, Sheldon J, Perales C (2019) Viral fitness: history and relevance for viral pathogenesis and antiviral interventions. Pathog Dis 77(2).

    • Doring M, Blees H, Koller N, Tischer-Zimmermann S, Musken M, Henrich F, Becker J, Grabski E, Wang J, Janssen H, Zuschratter W, Neefjes J, Klawonn F, Eiz-Vesper B, Tampe R, Kalinke U (2019) Modulation of TAP-dependent antigen compartmentalization during human monocyte-to-DC differentiation. Blood Adv 3(6): 839-850.

    • Durán V, Yasar H, Becker J, Thiyagarajan D, Loretz B, Kalinke U, Lehr CM (2019) Preferential uptake of chitosan-coated PLGA nanoparticles by primary human antigen presenting cells. Nanomedicine 21:(n/a): 102073.

    • Eggenschwiler R, Patronov A, Hegermann J, Fraguas-Eggenschwiler M, Wu G, Cortnumme L, Ochs M, Antes I, Cantz T (2019) A combined in silico and in vitro study on mouse Serpina1a antitrypsin-deficiency mutants. Sci Rep 9(1).

    • Erdmann J, Thöming JG, Pohl S, Pich A, Lenz C, Häussler S (2019) The Core Proteome of Biofilm-Grown Clinical Pseudomonas aeruginosa Isolates. Cells 8(10): 1129.

    • Gao X, Nowak-Imialek M, Chen X, Chen D, Herrmann D, Ruan D, Chen ACH, Eckersley-Maslin MA, Ahmad S, Lee YL, Kobayashi T, Ryan D, Zhong J, Zhu J, Wu J, Lan G, Petkov S, Yang J, Antunes L, Campos LS, Fu B, Wang S, Yong Y, Wang X, Xue SG, Ge L, Liu Z, Huang Y, Nie T, Li P, Wu D, Pei D, Zhang Y, Lu L, Yang F, Kimber SJ, Reik W, Zou X, Shang Z, Lai L, Surani A, Tam PPL, Ahmed A, Yeung WSB, Teichmann SA, Niemann H, Liu P (2019) Establishment of porcine and human expanded potential stem cells. Nat Cell Biol 21(6): 687-699.

    • Gawish R, Bulat T, Biaggio M, Lassnig C, Bago-Horvath Z, Macho-Maschler S, Poelzl A, Simonovic N, Prchal-Murphy M, Rom R, Amenitsch L, Ferrarese L, Kornhoff J, Lederer T, Svinka J, Eferl R, Bosmann M, Kalinke U, Stoiber D, Sexl V, Krmpotic A, Jonjic S, Muller M, Strobl B (2019) Myeloid Cells Restrict MCMV and Drive Stress-Induced Extramedullary Hematopoiesis through STAT1. Cell Rep 26(9): 2394-2406 e5.

    • Gottschick C, Raupach-Rosin H, Langer S, Hassan L, Horn J, Dorendorf E, Caputo M, Bittner M, Beier L, Rubsamen N, Schlinkmann K, Zoch B, Guzman CA, Hansen G, Heselich V, Holzapfel E, Hubner J, Pietschmann T, Pieper DH, Pletz M, Riese P, Schmidt-Pokrzywniak A, Hartwig S, von Kaisenberg C, Aydogdu M, Buhles M, Dressler F, Eberl W, Haase R, Edler von Koch F, Feidicker S, Frambach T, Franz HGB, Guthmann F, Koch HG, Seeger S, Oberhoff C, Pauker W, Petry KU, Schild RL, Tchirikov M, Rohrig E, Mikolajczyk R (2019) Cohort profile: The LoewenKIDS Study - life-course perspective on infections, the microbiome and the development of the immune system in early childhood. Int J Epidemiol 48(4): 1382-1383.

    • Grobe S, Doberenz S, Ferreira K, Krueger J, Bronstrup M, Kaever V, Haussler S (2019) Identification and quantification of (t)RNA modifications in Pseudomonas aeruginosa by liquid chromatography-tandem mass spectrometry. Chembiochem 20(11): 1430-1437.

    • Grylka-Baeschlin S, Clarke M, Begley C, Daly D, Healy P, Nicoletti J, Devane D, Morano S, Krause G, Karch A, Savage G, Gross MM (2019) Labour characteristics of women achieving successful vaginal birth after caesarean section in three European countries. Midwifery 74:(n/a): 36-43.

    • Heidegger S, Kreppel D, Bscheider M, Stritzke F, Nedelko T, Wintges A, Bek S, Fischer JC, Graalmann T, Kalinke U, Bassermann F, Haas T, Poeck H (2019) RIG-I activating immunostimulatory RNA boosts the efficacy of anticancer vaccines and synergizes with immune checkpoint blockade. EBioMedicine 41:(n/a): 146-155.

    • Helfritz FA, Wanders V, Bojkova D, Kuklinski N, Westhaus S, Swoboda S, Minor T, Meuleman P, Paul A, Steinmann E, Ciesek S (2019) Infectivity and stability of hepatitis C virus in different perfusion solutions. Transpl Infect Dis n/a(n/a): e13135.

    • Hengge R, Häussler S, Pruteanu M, Stülke J, Tschowri N, Turgay K (2019) Recent Advances and Current Trends in Nucleotide Second Messenger Signaling in Bacteria. J Mol Biol 431(5): 908-927.

    • Hensel N, Raker V, Forthmann B, Detering NT, Kubinski S, Buch A, Katzilieris-Petras G, Spanier J, Gudi V, Wagenknecht S, Kopfnagel V, Werfel TA, Stangel M, Beineke A, Kalinke U, Paludan SR, Sodeik B, Claus P (2019) HSV-1 triggers paracrine fibroblast growth factor response from cortical brain cells via immediate-early protein ICP0. J Neuroinflammation 16(1): 248.

    • Herrador A, Fedeli C, Radulovic E, Campbell KP, Moreno H, Gerold G, Kunz S (2019) Dynamic Dystroglycan Complexes Mediate Cell Entry of Lassa Virus. MBio 10(2).

    • Hong Z, Bolard A, Giraud C, Prevost S, Genta-Jouve G, Deregnaucourt C, Haussler S, Jeannot K, Li Y (2019) Azetidine-Containing Alkaloids Produced by a Quorum-Sensing Regulated Nonribosomal Peptide Synthetase Pathway in Pseudomonas aeruginosa. Angew Chem Int Ed Engl 58(10): 3178-3182.

    • Hornischer K, Khaledi A, Pohl S, Schniederjans M, Pezoldt L, Casilag F, Muthukumarasamy U, Bruchmann S, Thoming J, Kordes A, Haussler S (2019) BACTOME-a reference database to explore the sequence- and gene expression-variation landscape of Pseudomonas aeruginosa clinical isolates. Nucleic Acids Res 47(D1): D716-D720.

    • Kalodimou G, Veit S, Jany S, Kalinke U, Broder CC, Sutter G, Volz A (2019) A soluble version of Nipah Virus glycoprotein G delivered by vaccinia virus MVA activates specific CD8 and CD4 T cells in mice. Viruses 12(1): 26.

    • Kaszab E, Rado J, Kriszt B, Paszti J, Lesinszki V, Szabo S, Toth G, Khaledi A, Szoboszlay S (2019) Groundwater, soil and compost, as possible sources of virulent and antibiotic-resistant Pseudomonas aeruginosa. Int J Environ Health Res n/a(n/a): 1-13.

    • Khera T, Behrendt P, Bankwitz D, Brown RJP, Todt D, Doepke M, Khan AG, Schulze K, Law J, Logan M, Hockman D, Wong JAJ-X, Dold L, Gonzalez-Motos V, Spengler U, Viejo-Borbolla A, Ströh L, Krey T, Tarr AW, Steinmann E, Manns MP, Klein F, Guzman CA, Marcotrigiano J, Houghton M, Pietschmann T (2019) Functional and immunogenic characterization of diverse HCV glycoprotein E2 variants. J Hepatol 70(4): 593-602.

    • Kinast V, Leber SL, Brown RJP, Vieyres G, Behrendt P, Essbach C, Strnad P, Vondran FWR, Cornberg M, Wex C, Pietschmann T, Haybaeck J, Todt D, Steinmann E (2019) Identification of Keratin 23 as a Hepatitis C Virus-Induced Host Factor in the Human Liver. Cells 8(6).

    • Kleinert RDV, Montoya-Diaz E, Khera T, Welsch K, Tegtmeyer B, Hoehl S, Ciesek S, Brown RJP (2019) Yellow Fever: Integrating Current Knowledge with Technological Innovations to Identify Strategies for Controlling a Re-Emerging Virus. Viruses 11(10): 960.

    • Knop L, Frommer C, Stoycheva D, Deiser K, Kalinke U, Blankenstein T, Kammertoens T, Dunay IR, Schüler T (2019) Interferon-gamma Receptor Signaling in Dendritic Cells Restrains Spontaneous Proliferation of CD4(+) T Cells in Chronic Lymphopenic Mice. Front Immunol 10:(n/a): 140.

    • Kordes A, Grahl N, Koska M, Preusse M, Arce-Rodriguez A, Abraham WR, Kaever V, Häussler S (2019) Establishment of an induced memory response in Pseudomonas aeruginosa during infection of a eukaryotic host. ISME J 13(8): 2018-2030.

    • Kordes A, Preusse M, Willger SD, Braubach P, Jonigk D, Haverich A, Warnecke G, Häussler S (2019) Genetically diverse Pseudomonas aeruginosa populations display similar transcriptomic profiles in a cystic fibrosis explanted lung. Nat Commun 10(1): 3397.

    • Köllmann C, Wiechert SM, Jones PG, Pietschmann T, Werz DB (2019) Synthesis of 4'/5'-Spirocyclopropanated Uridine and d-Xylouridine Derivatives and Their Activity against the Human Respiratory Syncytial Virus. Org Lett 21(17): 6966-6971.

    • Lercher A, Bhattacharya A, Popa AM, Caldera M, Schlapansky MF, Baazim H, Agerer B, Gürtl B, Kosack L, Majek P, Brunner JS, Vitko D, Pinter T, Genger JW, Orlova A, Pikor N, Reil D, Ozsvar-Kozma Maria, Kalinke U, Ludewig B, Moriggl R, Bennett KL, Menche J, Cheng PN, Schabbauer G, Trauner M, Klavins K, Bergthaler A (2019) Type I Interferon Signaling Disrupts the Hepatic Urea Cycle and Alters Systemic Metabolism to Suppress T Cell Function. Immunity 51(6): 1074-1087.e9.

    • Lorenz A, Preusse M, Bruchmann S, Pawar V, Grahl N, Pils MC, Nolan LM, Filloux A, Weiss S, Haussler S (2019) Importance of flagella in acute and chronic Pseudomonas aeruginosa infections. Environ Microbiol 21(3): 883-897.

    • Mamareli P, Kruse F, Friedrich C, Smit N, Strowig T, Sparwasser T, Lochner M (2019) Epithelium-specific MyD88 signaling, but not DCs or macrophages, control acute intestinal infection with Clostridium difficile. Eur J Immunol 49(5): 747-757.

    • Martin-Benlloch X, Haid S, Novodomska A, Rominger F, Pietschmann T, Davioud-Charvet E, Elhabiri M (2019) Physicochemical Properties Govern the Activity of Potent Antiviral Flavones. ACS Omega 4(3): 4871-4887.

    • Meister T.L., Tegtmeyer B., Postel A., Cavalleri J.V., Todt D., Stang A., Steinmann E. (2019) Equine Parvovirus-Hepatitis Frequently Detectable in Commercial Equine Serum Pools. Viruses 11(5).

    • Meister TL, Tegtmeyer B, Brüggemann Y, Sieme H, Feige K, Todt D, Stang A, Cavalleri JV, Steinmann E (2019) Characterization of Equine Parvovirus in Thoroughbred Breeding Horses from Germany. Viruses 11(10): 965.

    • Mogilenko DA, Haas JT, L'homme L, Fleury S, Quemener S, Levavasseur M, Becquart C, Wartelle J, Bogomolova A, Pineau L, Molendi-Coste O, Lancel S, Dehondt H, Gheeraert C, Melchior A, Dewas C, Nikitin A, Pic S, Rabhi N, Annicotte JS, Oyadomari S, Velasco-Hernandez T, Cammenga J, Foretz M, Viollet B, Vukovic M, Villacreces A, Kranc K, Carmeliet P, Marot G, Boulter A, Tavernier S, Berod L, Longhi MP, Paget C, Janssens S, Staumont-Salle D, Aksoy E, Staels B, Dombrowicz D (2019) Metabolic and Innate Immune Cues Merge into a Specific Inflammatory Response via the UPR. Cell 177(5): 1201-1216.

    • Moreno H, Moller R, Fedeli C, Gerold G, Kunz S (2019) Comparison of the innate immune response to pathogenic and non-pathogenic Clade B New World arenaviruses. J Virol 93(19).

    • Ott M, Castell JV (2019) Hepatocyte transplantation, a step forward?. J Hepatol 70(6): 1049-1050.

    • Passos V, Zillinger T, Casartelli N, Wachs AS, Xu S, Malassa A, Steppich K, Schilling H, Franz S, Todt D, Steinmann E, Sutter K, Dittmer U, Bohne J, Schwartz O, Barchet W, Goffinet C (2019) Characterization of Endogenous SERINC5 Protein as anti-HIV-1 Factor. J Virol 93(24).

    • Pietschmann T, Brown RJP (2019) Hepatitis C Virus. Trends Microbiol 27(4): 379-380.

    • Praditya D, Kirchhoff L, Brüning J, Rachmawati H, Steinmann J, Steinmann E (2019) Anti-infective Properties of the Golden Spice Curcumin. Front Microbiol 10:(n/a): 912.

    • Ramli SR, Moreira GMSG, Zantow J, Goris MGA, Nguyen VK, Novoselova N, Pessler F, Hust M (2019) Discovery of Leptospira spp. seroreactive peptides using ORFeome phage display. PLoS Negl Trop Dis 13(1): 1-18.

    • Ratuszny D, Suhs KW, Novoselova N, Kuhn M, Kaever V, Skripuletz T, Pessler F, Stangel M (2019) Identification of Cerebrospinal Fluid Metabolites as Biomarkers for Enterovirus Meningitis. Int J Mol Sci 20(2).

    • Ruangkiattikul N, Rys D, Abdissa K, Rohde M, Semmler T, Tegtmeyer PK, Kalinke U, Schwarz C, Lewin A, Goethe R (2019) Type I interferon induced by TLR2-TLR4-MyD88-TRIF-IRF3 controls Mycobacterium abscessus subsp. abscessus persistence in murine macrophages via nitric oxide. Int J Med Microbiol 309(5): 307-318.

    • Sandargo B, Michehl M, Praditya D, Steinmann E, Stadler M, Surup F (2019) Antiviral Meroterpenoid Rhodatin and Sesquiterpenoids Rhodocoranes A–E from the Wrinkled Peach Mushroom, Rhodotus palmatus. Org Lett 21(9): 3286-3289.

    • Schlevogt B, Kinast V, Reusch J, Kerkhoff A, Praditya D, Todt D, Schmidt HH, Steinmann E, Behrendt P (2019) Chronic Hepatitis E Virus Infection during Lymphoplasmacytic Lymphoma and Ibrutinib Treatment. Pathogens 8(3).

    • Serradell MC, Rupil LL, Martino RA, Prucca CG, Carranza PG, Saura A, Fernández EA, Gargantini PR, Tenaglia AH, Petiti JP, Tonelli RR, Reinoso-Vizcaino N, Echenique J, Berod L, Piaggio E, Bellier B, Sparwasser T, Klatzmann D, Luján HD (2019) Efficient oral vaccination by bioengineering virus-like particles with protozoan surface proteins. Nat Commun 10(1): 361.

    • Sohail MU, Yassine HM, Sohail A, Al Thani AA (2019) Impact of Physical Exercise on Gut Microbiome, Inflammation, and the Pathobiology of Metabolic Disorders. Rev Diabet Stud 15(1): 35-48.

    • Solmaz G, Puttur F, Francozo M, Lindenberg M, Guderian M, Swallow M, Duhan V, Khairnar V, Kalinke U, Ludewig B, Clausen BE, Wagner H, Lang KS, Sparwasser TD (2019) TLR7 Controls VSV Replication in CD169 (+) SCS Macrophages and Associated Viral Neuroinvasion. Front Immunol 10:(n/a): 466.

    • Solmaz G, Puttur F, Francozo M, Lindenberg M, Guderian M, Swallow M, Duhan V, Khairnar V, Kalinke U, Ludewig B, Clausen BE, Wagner H, Lang KS, Sparwasser TD (2019) TLR7 Controls VSV Replication in CD169(+) SCS Macrophages and Associated Viral Neuroinvasion. Front Immunol 10:(n/a): 466.

    • Soon CF, Behrendt P, Todt D, Manns MP, Wedemeyer H, Chen MS, Cornberg M (2019) Defining virus-specific CD8+ TCR repertoires for therapeutic regeneration of T cells against chronic hepatitis E. J Hepatol 71(4): 673-684.

    • Springer A, Heuer L, Janecek-Erfurth E, Beineke A, Strube C (2019) Histopathological characterization of Toxocara canis- and T. cati-induced neurotoxocarosis in the mouse model. Parasitol Res 118(9): 2591-2600.

    • Steel N, Faniyi AA, Rahman S, Swietlik S, Czajkowska BI, Chan BT, Hardgrave A, Steel A, Sparwasser TD, Assas MB, Grencis RK, Travis MA, Worthington JJ (2019) TGFβ-activation by dendritic cells drives Th17 induction and intestinal contractility and augments the expulsion of the parasite Trichinella spiralis in mice. PLOS Pathog 15(4): 1-25.

    • Suhs KW, Novoselova N, Kuhn M, Seegers L, Kaever V, Muller-Vahl K, Trebst C, Skripuletz T, Stangel M, Pessler F (2019) Kynurenine is a cerebrospinal fluid biomarker for bacterial and viral CNS infections. J Infect Dis 220(1): 127-138.

    • Tegtmeyer B, Echelmeyer J, Pfankuche VM, Puff C, Todt D, Fischer N, Durham A, Feige K, Baumgartner W, Steinmann E, Cavalleri JV (2019) Chronic equine hepacivirus infection in an adult gelding with severe hepatopathy. Vet Med Sci 5(3): 372-378.

    • Tegtmeyer PK, Spanier J, Borst K, Becker J, Riedl A, Hirche C, Ghita L, Skerra J, Baumann K, Lienenklaus S, Doering M, Ruzsics Z, Kalinke U (2019) STING induces early IFN-β in the liver and constrains myeloid cell-mediated dissemination of murine cytomegalovirus. Nat Commun 10(1): 2830.

    • Tsay HC, Yuan Q, Balakrishnan A, Kaiser M, Möbus S, Kozdrowska E, Farid M, Tegtmeyer PK, Borst K, Vondran FWR, Kalinke U, Kispert A, Manns MP, Ott M, Sharma AD (2019) Hepatocyte-specific suppression of microRNA-221-3p mitigates liver fibrosis. J Hepatol 70(4): 722-734.

    • Tsay HC, Yuan Q, Balakrishnan A, Kaiser M, Möbus S, Kozdrowska E, Farid M, Tegtmeyer PK, Borst K, Vondran FWR, Kalinke U, Kispert A, Manns MP, Ott M, Sharma AD (2019) Hepatocyte-specific suppression of microRNA-221-3p mitigates liver fibrosis. J Hepatol 70(4): 722-734.

    • Uckeley ZM, Moeller R, Kühn LI, Nilsson E, Robens C, Lasswitz L, Lindqvist R, Lenman A, Passos V, Voss Y, Sommerauer C, Kampmann M, Goffinet C, Meissner F, Överby AK, Lozach PY, Gerold G (2019) Quantitative proteomics of Uukuniemi virus - host cell interactions reveals GBF1 as proviral host factor for phleboviruses. Mol Cell Proteomics 18(12): 2401-2417.

    • Vieyres G, Pietschmann T (2019) HCV Pit Stop at the Lipid Droplet: Refuel Lipids and Put on a Lipoprotein Coat before Exit. Cells 8(3).

    • Waindok P, Özbakis-Beceriklisoy G, Janecek-Erfurth E, Springer A, Pfeffer M, Leschnik M, Strube C (2019) Parasites in brains of wild rodents (Arvicolinae and Murinae) in the city of Leipzig, Germany. Int J Parasitol Parasites Wildl 10(n/a): 211-217.

    • Wang Y, Dembowsky K, Chevalier E, Stüve P, Korf-Klingebiel M, Lochner M, Napp LC, Frank H, Brinkmann E, Kanwischer A, Bauersachs J, Gyongyosi M, Sparwasser T, Wollert KC (2019) C-X-C Motif Chemokine Receptor 4 Blockade Promotes Tissue Repair After Myocardial Infarction by Enhancing Regulatory T Cell Mobilization and Immune-Regulatory Function. Circulation 139(15): 1798-1812.

    • Wawro N, Amann U, Butt J, Meisinger C, Akmatov MK, Pessler F, Peters A, Rathmann W, Kääb S, Waterboer T, Linseisen J (2019) Helicobacter pylori Seropositivity: Prevalence, Associations, and the Impact on Incident Metabolic Diseases/Risk Factors in the Population-Based KORA Study. Front Public Health 7:(n/a): 96.

    • Wibowo JT, Kellermann MY, Versluis D, Putra MY, Murniasih T, Mohr KI, Wink J, Engelmann M, Praditya DF, Steinmann E, Schupp PJ (2019) Biotechnological potential of bacteria isolated from the sea cucumber holothuria leucospilota and stichopus vastus from Lampung, Indonesia. Mar Drugs 17(11): 635.

    • Wicker E, Lander F, Weidemann F, Hufnagel M, Berner R, Krause G (2019) Group B Streptococci: Declining Incidence in Infants in Germany. Pediatr Infect Dis J 38(5): 516-519.

    • Zapatero-Belinchon FJ, Dietzel E, Dolnik O, Dohner K, Costa R, Hertel B, Veselkova B, Kirui J, Klintworth A, Manns MP, Pohlmann S, Pietschmann T, Krey T, Ciesek S, Gerold G, Sodeik B, Becker S, von Hahn T (2019) Characterization of the Filovirus-Resistant Cell Line SH-SY5Y Reveals Redundant Role of Cell Surface Entry Factors. Viruses 11(3).

    • Ziegler A, Hinz T, Kalinke U (2019) RNA-Based Adjuvants: Immunoenhancing Effect on Antiviral Vaccines and Regulatory Considerations. Crit Rev Immunol 39(1): 1-14.

    • de Araujo LS, Ribeiro-Alves M, Leal-Calvo T, Leung J, Duran V, Samir M, Talbot S, Tallam A, Mello FCQ, Geffers R, Saad MHF, Pessler F (2019) Reprogramming of Small Noncoding RNA Populations in Peripheral Blood Reveals Host Biomarkers for Latent and Active Mycobacterium tuberculosis Infection. mBio(10): 6.

    2018

    • Abere B, Samarina N, Gramolelli S, Ruckert J, Gerold G, Pich A, Schulz TF (2018) Kaposi's Sarcoma-Associated Herpesvirus Nonstructural Membrane Protein pK15 Recruits the Class II Phosphatidylinositol 3-Kinase PI3K-C2alpha To Activate Productive Viral Replication. J Virol 92(17).

    • Akeus P, Szeponik L, Ahlmanner F, Sundström P, Alsen S, Gustavsson B, Sparwasser T, Raghavan S, Quiding-Jarbrink M (2018) Regulatory T cells control endothelial chemokine production and migration of T cells into intestinal tumors of APCmin/+ mice. Cancer Immunol Immunother 67(7): 1067-1077.

    • Akmatov MK, Rübsamen N, Deyneko IV, Karch A, Mikolajczyk RT (2018) Poor knowledge of vaccination recommendations and negative attitudes towards vaccinations are independently associated with poor vaccination uptake among adults – Findings of a population-based panel study in Lower Saxony, Germany. Vaccine 36(18): 2417-2426.

    • Alissafi T, Kourepini E, Simoes DCM, Paschalidis N, Aggelakopoulou M, Sparwasser T, Boon L, Hammad H, Lambrecht BN, Panoutsakopoulou V (2018) Osteopontin Promotes Protective Antigenic Tolerance against Experimental Allergic Airway Disease. j Immunol 200(4): 1270-1282.

    • Andreas N, Riemann M, Castro CN, Groth M, Koliesnik I, Engelmann C, Sparwasser T, Kamradt T, Haenold R, Weih F (2018) A new RelB-dependent CD117+ CD172a+ murine dendritic cell subset preferentially induces Th2 differentiation and supports airway hyperresponses in vivo. Eur J Immunol 48(6): 923-936.

    • Badenhorst M, Tegtmeyer B, Todt D, Guthrie A, Feige K, Campe A, Steinmann E, Cavalleri JMV (2018) First detection and frequent occurrence of Equine Hepacivirus in horses on the African continent. Vet Microbiol 223:(n/a): 51-58.

    • Baier C, Haid S, Beilken A, Behnert A, Wetzke M, Brown RJP, Schmitt C, Ebadi E, Hansen G, Schulz TF, Pietschmann T, Bange FC (2018) Molecular characteristics and successful management of a respiratory syncytial virus outbreak among pediatric patients with hemato-oncological disease. Antimicrob Resist Infect Control 7:(n/a): 21.

    • Banse P, Moeller R, Bruening J, Lasswitz L, Kahl S, Khan AG, Marcotrigiano J, Pietschmann T, Gerold G (2018) CD81 Receptor Regions outside the Large Extracellular Loop Determine Hepatitis C Virus Entry into Hepatoma Cells. Viruses 10(4): 207.

    • Bartenschlager R, Baumert TF, Bukh J, Houghton M, Lemon SM, Lindenbach BD, Lohmann V, Moradpour D, Pietschmann T, Rice CM, Thimme R, Wakita T (2018) Critical challenges and emerging opportunities in hepatitis C virus research in an era of potent antiviral therapy: considerations for scientists and funding agencies. Virus Res 248:(n/a): 53-62.

    • Becker J, Kinast V, Doring M, Lipps C, Duran V, Spanier J, Tegtmeyer PK, Wirth D, Cicin-Sain L, Alcami A, Kalinke U (2018) Human monocyte-derived macrophages inhibit HCMV spread independent of classical antiviral cytokines. Virulence 9(1): 1669-1684.

    • Bieling M, Tischer S, Kalinke U, Blasczyk R, Buus S, Maecker-Kolhoff B, Eiz-Vesper B (2018) Personalized adoptive immunotherapy for patients with EBV-associated tumors and complications: Evaluation of novel naturally processed and presented EBV-derived T-cell epitopes. Oncotarget 9(4): 4737-4757.

    • Bohm K, Krause G, Sievers C (2018) Response to comment on: Validation of HAV biomarker 2A for differential diagnostic of hepatitis A infected and vaccinated individuals using multiplex serology. Vaccine 36(27): 3885.

    • Borst K, Frenz T, Spanier J, Tegtmeyer PK, Chhatbar C, Skerra J, Ghita L, Namineni S, Lienenklaus S, Köster M, Heikenwaelder M, Sutter G, Kalinke U (2018) Type I interferon receptor-signaling delays Kupffer cell replenishment during acute fulminant viral hepatitis. J Hepatol 68(4): 682-690.

    • Bruening J, Lasswitz L, Banse P, Kahl S, Marinach C, Vondran FW, Kaderali L, Silvie O, Pietschmann T, Meissner F, Gerold G (2018) Hepatitis C virus enters liver cells using the CD81 receptor complex proteins calpain-5 and CBLB. PLOS Pathog 14(7): 1-35.

    • Chen YL, Jing J, Mo YQ, Ma JD, Yang LJ, Chen LF, Zhang X, Yan T, Zheng DH, Pessler F, Dai L (2018) Presence of hepatitis B virus in synovium and its clinical significance in rheumatoid arthritis. Arthritis Res Ther 20(1): 130.

    • Chhatbar C, Detje CN, Grabski E, Borst K, Spanier J, Ghita L, Elliott DA, Jordao MJC, Mueller N, Sutton J, Prajeeth CK, Gudi V, Klein MA, Prinz M, Bradke F, Stangel M, Kalinke U (2018) Type I Interferon Receptor Signaling of Neurons and Astrocytes Regulates Microglia Activation during Viral Encephalitis. Cell Rep 25(1): 118-129.e4.

    • Ciccocioppo R, Dos Santos CC, Baumgart DC, Cangemi GC, Cardinale V, Ciacci C, De Coppi P, Haldar D, Klersy C, Nostro MC, Ott M, Piemonti L, Tomei AA, Uygun B, Vetrano S, Orlando G (2018) Proceedings of the signature series event of the international society for cellular therapy: Ädvancements in cellular therapies and regenerative medicine in digestive diseases," London, United Kingdom, May 3, 2017. Cytotherapy 20(3): 461-476.

    • Divakaruni AS, Hsieh WY, Minarrieta L, Duong TN, Kim KKO, Desousa BR, Andreyev A.Y, Bowman CE, Caradonna K, Dranka BP, Ferrick DA, Liesa M, Stiles L, Rogers GW, Braas D, Ciaraldi TP, Wolfgang MJ, Sparwasser T, Berod L, Bensinger SJ, Murphy AN (2018) Etomoxir Inhibits Macrophage Polarization by Disrupting CoA Homeostasis. Cell Metab 28(3): 490-503.e7.

    • Dreyer H, Grischke J, Tiede C, Eberhard J, Schweitzer A, Toikkanen SE, Glockner S, Krause G, Stiesch M (2018) Epidemiology and risk factors of peri-implantitis: A systematic review. J Periodontal Res 53(5): 657-681.

    • Eckweiler D, Häussler S (2018) Antisense transcription in Pseudomonas aeruginosa. Microbiology 164(6): 889--895.

    • Erdmann J, Preusse M, Khaledi A, Pich A, Haussler S (2018) Environment-driven changes of mRNA and protein levels in Pseudomonas aeruginosa. Environ Microbiol 20(11): 3952-3963.

    • Fedeli C, Torriani G, Galan-Navarro C, Moraz ML, Moreno H, Gerold G, Kunz S (2018) Axl Can Serve as Entry Factor for Lassa Virus Depending on the Functional Glycosylation of Dystroglycan. J Virol 92(5).

    • Franz S, Friesland M, Passos V, Todt D, Simmons G, Goffinet C, Steinmann E (2018) Susceptibility of Chikungunya Virus to Inactivation by Heat and Commercially and WHO-Recommended Biocides. J Infect Dis 218(9): 1507-1510.

    • Garcia-Nicolas O, V'Kovski P, Vielle NJ, Ebert N, Zust R, Portmann J, Stalder H, Gaschen V, Vieyres G, Stoffel M, Schweizer M, Summerfield A, Engler O, Pietschmann T, Todt D, Alves MP, Thiel V, Pfaender S (2018) The small compound inhibitor K22 displays broad antiviral activity against different members of the family Flaviviridae and offers potential as pan-viral inhibitor. Antimicrob Agents Chemother 62(11).

    • Happle C, Meyer-Decking L, Dreier A, Wetzke M, Gläsener S, Grychtol R, Braubach P, Jablonka A, Haid S, Jirmo AC, Habener A, Skuljec J, Hansen G (2018) Improved protocol for simultaneous analysis of leukocyte subsets and epithelial cells from murine and human lung. Exp Lung Res 44(3): 127-136.

    • Helfritz FA, Bojkova D, Wanders V, Kuklinski N, Westhaus S, von Horn C, Rauen U, Gallinat A, Baba HA, Skyschally A, Swoboda S, Kinast V, Steinmann E, Heusch G, Minor T, Meuleman P, Paul A, Ciesek S (2018) Methylene Blue Treatment of Grafts during Cold Ischemia time Reduces the Risk of HCV Transmission. J Infect Dis 218(11): 1711-1721.

    • Herzmann C, Dallenga T, Kalinke U (2018) Pulmonale Immunitat bei Tuberkulose. Pneumologie 72(7): 493-502.

    • Hetzel M, Mucci A, Blank P, Nguyen AHH, Schiller J, Halle O, Kuhnel MP, Billig S, Meineke R, Brand D, Herder V, Baumgartner W, Bange FC, Goethe R, Jonigk D, Forster R, Gentner B, Casanova JL, Bustamante J, Schambach A, Kalinke U, Lachmann N (2018) Hematopoietic stem cell gene therapy for IFNgammaR1 deficiency protects mice from mycobacterial infections. Blood 131(5): 533-545.

    • Junge N, Yuan Q, Vu TH, Krooss S, Bednarski C, Balakrishnan A, Cathomen T, Manns MP, Baumann U, Sharma AD, Ott M (2018) Homologous recombination mediates stable Fah gene integration and phenotypic correction in tyrosinaemia mouse-model. World J Hepatol 10(2): 277-286.

    • Kaufer C, Chhatbar C, Broer S, Waltl I, Ghita L, Gerhauser I, Kalinke U, Loscher W (2018) Chemokine receptors CCR2 and CX3CR1 regulate viral encephalitis-induced hippocampal damage but not seizures. Proc Natl Acad Sci U S A 115(38): E8929-E8938.

    • Knegendorf L, Drave SA, Dao Thi VL, Debing Y, Brown RJP, Vondran FWR, Resner K, Friesland M, Khera T, Engelmann M, Bremer B, Wedemeyer H., Behrendt P, Neyts J, Pietschmann T, Todt D, Steinmann E (2018) Hepatitis E virus replication and interferon responses in human placental cells. Hepatol Commun 2(2): 173-187.

    • Koestner W, Spanier J, Klause T, Tegtmeyer PK, Becker J, Herder V, Borst K, Todt D, Lienenklaus S, Gerhauser I, Detje CN, Geffers R, Langereis MA, Vondran FWR, Yuan Q, van Kuppeveld FJM, Ott M, Staeheli P, Steinmann E, Baumgartner W, Wacker F, Kalinke U (2018) Interferon-beta expression and type I interferon receptor signaling of hepatocytes prevent hepatic necrosis and virus dissemination in Coxsackievirus B3-infected mice. PLoS Pathog 14(8): e1007235.

    • Koestner W, Spanier J, Klause T, Tegtmeyer PK, Becker J, Herder V, Borst K, Todt D, Lienenklaus S, Gerhauser I, Detje CN, Geffers R, Langereis MA, Vondran FWR, Yuan Q, van Kuppeveld FJM, Ott M, Staeheli P, Steinmann E, Baumgartner W, Wacker F, Kalinke U (2018) Interferon-beta expression and type I interferon receptor signaling of hepatocytes prevent hepatic necrosis and virus dissemination in Coxsackievirus B3-infected mice. PLOS Pathog 14(8): 1-23.

    • Koestner W, Spanier J, Klause T, Tegtmeyer PK, Becker J, Herder V, Borst K, Todt D, Lienenklaus S, Gerhauser I, Detje CN, Geffers R, Langereis MA, Vondran FWR, Yuan Q, van Kuppeveld FJM, Ott M, Staeheli P, Steinmann E, Baumgartner W, Wacker F, Kalinke U, Klause Tanja, Tegtmeyer Pia-K., Becker Jennifer, Herder Vanessa, Borst Katharina, Todt Daniel, Lienenklaus Stefan, Gerhauser Ingo, Detje ClaudiaN., Geffers Robert, Langereis MartijnA., Vondran FlorianW.R., Yuan Qinggong, van Kuppeveld FrankJ.M., Ott Michael, Staeheli Peter, Steinmann Eike, Baumgärtner Wolfgang, Wacker Frank, Kalinke Ulrich (2018) Interferon-beta expression and type I interferon receptor signaling of hepatocytes prevent hepatic necrosis and virus dissemination in Coxsackievirus B3-infected mice. PLOS Pathog 14(8): 1-23.

    • Kuhn M, Suhs KW, Akmatov MK, Klawonn F, Wang J, Skripuletz T, Kaever V, Stangel M, Pessler F (2018) Mass-spectrometric profiling of cerebrospinal fluid reveals metabolite biomarkers for CNS involvement in varicella zoster virus reactivation. J Neuroinflammation 15(1): 20.

    • Lasswitz L, Chandra N, Arnberg N, Gerold G (2018) Glycomics and Proteomics Approaches to Investigate Early Adenovirus-Host Cell Interactions. J Mol Biol 430(13): 1863-1882.

    • Lipps C, Klein F, Wahlicht T, Seiffert V, Butueva M, Zauers J, Truschel T, Luckner M, Köster M, MacLeod R, Pezoldt J, Hühn J, Yuan Q, Müller PP, Kempf H, Zweigerdt R, Dittrich-Breiholz O, Pufe T, Beckmann R, Drescher W, Riancho J, Sañudo C, Korff T, Opalka B, Rebmann V, Göthert JR, Alves PM, Ott M, Schucht R, Hauser H, Wirth D, May T (2018) Expansion of functional personalized cells with specific transgene combinations. Nat Commun 9(1): 994.

    • Lodermeyer V, Ssebyatika G, Passos V, Ponnurangam A, Malassa A, Ewald E, Stürzel CM, Kirchhoff F, Rotger M, Falk CS, Telenti A, Krey T, Goffinet C (2018) The Antiviral Activity of the Cellular Glycoprotein LGALS3BP/90K is Species-Specific. J Virol 92(14).

    • Loof TG, Sohail A, Bahgat MM, Tallam A, Arshad H, Akmatov MK, Pils MC, Heise U, Beineke A, Pessler F (2018) Early Lymphocyte Loss and Increased Granulocyte/Lymphocyte Ratio Predict Systemic Spread of Streptococcus pyogenes in a Mouse Model of Acute Skin Infection. Front Cell Infect Microbiol 8:(n/a): 101.

    • Muller L, Murgia X, Siebenburger L, Borger C, Schwarzkopf K, Sewald K, Haussler S, Braun A, Lehr CM, Hittinger M, Wronski S (2018) Human airway mucus alters susceptibility of Pseudomonas aeruginosa biofilms to tobramycin, but not colistin. J Antimicrob Chemother 73(10): 2762-2769.

    • Mulwa LS, Jansen R, Praditya DF, Mohr KI, Okanya PW, Wink J, Steinmann E, Stadler M (2018) Lanyamycin, a macrolide antibiotic from Sorangium cellulosum, strain Soce 481 (Myxobacteria). Beilstein J Org Chem 14:(n/a): 1554-1562.

    • Mulwa LS, Jansen R, Praditya DF, Mohr KI, Wink J, Steinmann E, Stadler M (2018) Six Heterocyclic Metabolites from the Myxobacterium Labilithrix luteola. Molecules 23(3): 542.

    • Musken M, Pawar V, Schwebs T, Bahre H, Felgner S, Weiss S, Haussler S (2018) Breaking the vicious cycle of antibiotic killing and regrowth of biofilm-residing Pseudomonas aeruginosa. Antimicrob Agents Chemother 62(12).

    • Mzinza DT, Fleige H, Laarmann K, Willenzon S, Ristenpart J, Spanier J, Sutter G, Kalinke U, Valentin-Weigand P, Förster R (2018) Application of light sheet microscopy for qualitative and quantitative analysis of bronchus-associated lymphoid tissue in mice. Cellular & Molecular Immunology 15(10): 875-887.

    • Narendra SC, Chalise JP, Biggs S, Kalinke U, Magnusson M (2018) Regulatory T-Cells Mediate IFN-alpha-Induced Resistance against Antigen-Induced Arthritis. Front Immunol 9:(n/a): 285.

    • Neehus AL, Lam J, Haake K, Merkert S, Schmidt N, Mucci A, Ackermann M, Schubert M, Happle C, Kuhnel MP, Blank P, Philipp F, Goethe R, Jonigk D, Martin U, Kalinke U, Baumann U, Schambach A, Roesler J, Lachmann N (2018) Impaired IFNgamma-Signaling and Mycobacterial Clearance in IFNgammaR1-Deficient Human iPSC-Derived Macrophages. Stem Cell Reports 10(1): 7-16.

    • Olmer R, Engels L, Usman A, Menke S, Malik MNH, Pessler F, Göhring G, Bornhorst D, Bolten S, Abdelilah-Seyfried S, Scheper T, Kempf H, Zweigerdt R, Martin U (2018) Differentiation of Human Pluripotent Stem Cells into Functional Endothelial Cells in Scalable Suspension Culture. Stem Cell Reports 10(5): 1657-1672.

    • Olsowski M, Hoffmann F, Hain A, Kirchhoff L, Theegarten D, Todt D, Steinmann E, Buer J, Rath PM, Steinmann J (2018) Exophiala dermatitidis isolates from various sources: using alternative invertebrate host organisms (Caenorhabditis elegans and Galleria mellonella) to determine virulence. Sci Rep 8(1): 12747.

    • Paul-Heng M, Leong M, Cunningham E, Bunker DLJ, Bremner K, Wang Z, Wang C, Tay SS, McGuffog C, Logan GJ, Alexander IE, Hu M, Alexander SI, Sparwasser TD, Bertolino P, Bowen DG, Bishop GA, Sharland A (2018) Direct recognition of hepatocyte-expressed MHC class I alloantigens is required for tolerance induction. JCI Insight 3(15).

    • Petersen H, Mostafa A, Tantawy MA, Iqbal AA, Hoffmann D, Tallam A, Selvakumar B, Pessler F, Beer M, Rautenschlein S, Pleschka S (2018) NS Segment of a 1918 Influenza A Virus-Descendent Enhances Replication of H1N1pdm09 and Virus-Induced Cellular Immune Response in Mammalian and Avian Systems. Front Microbiol 9:(n/a): 526.

    • Pfaender S, Helfritz FA, Siddharta A, Todt D, Behrendt P, Heyden J, Riebesehl N, Willmann W, Steinmann J, Münch J, Ciesek S, Steinmann E (2018) Environmental Stability and Infectivity of Hepatitis C Virus (HCV) in Different Human Body Fluids. Frontiers in Microbiology 9:(n/a): 504.

    • Pfankuche VM, Hahn K, Bodewes R, Hansmann F, Habierski A, Haverkamp AK, Pfaender S, Walter S, Baechlein C, Postel A, Steinmann E, Becher P, Osterhaus A, Baumgartner W, Puff C (2018) Comparison of Different In Situ Hybridization Techniques for the Detection of Various RNA and DNA Viruses. Viruses 10(7): 384.

    • Pägelow D, Chhatbar C, Beineke A, Liu X, Nerlich A, van Vorst K, Rohde M, Kalinke U, Förster R, Halle S, Valentin-Weigand P, Hornef MW, Fulde M (2018) The olfactory epithelium as a port of entry in neonatal neurolisteriosis. Nat Commun 9(1): 4269.

    • Raud B, McGuire PJ, Jones RG, Sparwasser T, Berod L (2018) Fatty acid metabolism in CD8(+) T cell memory: Challenging current concepts. Immunol Rev 283(1): 213-231.

    • Raud B, Roy DG, Divakaruni AS, Tarasenko TN, Franke R, Ma EH, Samborska B, Hsieh WY, Wong AH, Stüve P, Arnold-Schrauf C, Guderian M, Lochner M, Rampertaap S, Romito K, Monsale J, Brönstrup M, Bensinger SJ, Murphy AN, McGuire PJ, Jones RG, Sparwasser T, Berod L (2018) Etomoxir Actions on Regulatory and Memory T Cells Are Independent of Cpt1a-Mediated Fatty Acid Oxidation. Cell Metab 28(3): 504-515.e7.

    • Samir M, Hamed M, Abdallah F, Kinh Nguyen V, Hernandez-Vargas EA, Seehusen F, Baumgartner W, Hussein A, Ali AAH, Pessler F (2018) An Egyptian HPAI H5N1 isolate from clade 2.2.1.2 is highly pathogenic in an experimentally infected domestic duck breed (Sudani duck). Transbound Emerg Dis 65(3): 859-873.

    • Sandargo B, Thongbai B, Praditya D, Steinmann E, Stadler M, Surup F (2018) Antiviral 4-Hydroxypleurogrisein and Antimicrobial Pleurotin Derivatives from Cultures of the Nematophagous Basidiomycete Hohenbuehelia grisea. Molecules 23(10).

    • Schleicher U, Liese J, Justies N, Mischke T, Haeberlein S, Sebald H, Kalinke U, Weiss S, Bogdan C (2018) Type I Interferon Signaling Is Required for CpG-Oligodesoxynucleotide-Induced Control of Leishmania major, but Not for Spontaneous Cure of Subcutaneous Primary or Secondary L. major Infection. Frontiers in Immunology 9:(n/a): 79.

    • Semitekolou M, Morianos I, Banos A, Konstantopoulos D, Adamou-Tzani M, Sparwasser T, Xanthou G (2018) Dendritic cells conditioned by activin-A-induced regulatory T cells exhibit enhanced tolerogenic properties and protect against experimental asthma. J Allergy Clin Immunol 141(2): 671-684e7.

    • Serradell MC, Gargantini PR, Saura A, Oms SR, Rupil LL, Berod L, Sparwasser T, Luján HD (2018) Cytokines, antibodies and histopathological profiles during Giardia infection and VSP-based vaccination. Infect Immuno 86(6).

    • Seufert R, Sedlacek L, Kahl B, Hogardt M, Hamprecht A, Haase G, Gunzer F, Haas A, Grauling-Halama S, MacKenzie CR, Essig A, Stehling F, Sutharsan S, Dittmer S, Killengray D, Schmidt D, Eskandarian N, Steinmann E, Buer J, Hagen F, Meis JF, Rath PM, Steinmann J (2018) Prevalence and characterization of azole-resistant Aspergillus fumigatus in patients with cystic fibrosis: a prospective multicentre study in Germany. J Antimicrob Chemother 73(8): 2047-2053.

    • Singpiel A, Kramer J, Maus R, Stolper J, Bittersohl LF, Gauldie J, Kolb M, Welte T, Sparwasser T, Maus UA (2018) Adenoviral vector-mediated GM-CSF gene transfer improves anti-mycobacterial immunity in mice - role of regulatory T cells. Immunobiology 223(3): 331-341.

    • Skripuletz T, Pars K, Schulte A, Schwenkenbecher P, Yildiz O, Ganzenmueller T, Kuhn M, Spreer A, Wurster U, Pul R, Stangel M, Suhs KW, Trebst C (2018) Varicella zoster virus infections in neurological patients: a clinical study. BMC Infect Dis 18(1): 238.

    • Strehlitz A, Goldmann O, Pils MC, Pessler F, Medina E (2018) An Interferon Signature Discriminates Pneumococcal From Staphylococcal Pneumonia. Frontiers in Immunology 9:(n/a): 1424.

    • Stüve P, Minarrieta L, Erdmann H, Arnold-Schrauf C, Swallow M, Guderian M, Krull F, Hölscher A, Ghorbani P, Behrends J, Abraham WR, Hölscher C, Sparwasser T, Berod L (2018) De novo fatty acid synthesis during mycobacterial infection is a prerequisite for the function of highly proliferative T cells, but not for dendritic cells or macrophages. Front Immunol 9:(n/a): 495.

    • Tappe KA, Budida R, Stankov MV, Frenz T, H R.Shah, Volz A, Sutter G, Kalinke U, Behrens GMN (2018) Immunogenic cell death of dendritic cells following modified vaccinia virus Ankara infection enhances CD8(+) T cell proliferation. Eur J Immunol 48(12): 2042-2054.

    • Todt D, Moeller N, Praditya D, Kinast V, Friesland M, Engelmann M, Verhoye L, Sayed IM, Behrendt P, Thi VLD, Meuleman Philip, Steinmann Eike (2018) The natural compound silvestrol inhibits hepatitis E virus (HEV) replication in vitro and in vivo. Antiviral Res 157:(n/a): 151--158.

    • Velasquez L, Stüve P, Gentilini M, Swallow M, Bartel J, Lycke N, Barkan N, Martina M, Lujan H, Kalay H, Van Kooyk Y, Sparwasser T, Berod L (2018) Targeting mycobacterium tuberculosis antigens to dendritic cells via the DC-SIGN receptor induces strong Th1 immune responses.. Front Immunol 9:(n/a): 471.

    • Vendelova E, Ashour D, Blank P, Erhard F, Saliba AE, Kalinke U, Lutz MB (2018) Tolerogenic Transcriptional Signatures of Steady-State and Pathogen-Induced Dendritic Cells. Front Immunol 9:(n/a): 333.

    • Villacorta L, Minarrieta L, Salvatore SR, Khoo NK, Rom O, Gao Z, Berman RC, Jobbagy S, Li L, Woodcock SR, Chen YE, Freeman BA, Ferreira AM, Schopfer FJ, Vitturi DA (2018) In situ generation, metabolism and immunomodulatory signaling actions of nitro-conjugated linoleic acid in a murine model of inflammation. Redox Biol 15(n/a): 522-531.

    • Waltl I, Käufer C, Bröer S, Chhatbar C, Ghita L, Gerhauser I, Anjum M, Kalinke U, Löscher W (2018) Macrophage depletion by liposome-encapsulated clodronate suppresses seizures but not hippocampal damage after acute viral encephalitis. Neurobiol Dis 110:(n/a): 192-205.

    • Waltl I, Käufer C, Gerhauser I, Chhatbar C, Ghita L, Kalinke U, Löscher W (2018) Microglia have a protective role in viral encephalitis-induced seizure development and hippocampal damage. Brain Behav Immun 74:(n/a): 186-204.

    • Wolling H, Konze SA, Hofer A, Erdmann J, Pich A, Zweigerdt R, Buettner FFR (2018) Quantitative Secretomics Reveals Extrinsic Signals Involved in Human Pluripotent Stem Cell Cardiomyogenesis. Proteomics 18(14): e1800102.

    • Xie Y, Zhang H, Guo XJ, Feng YC, He RZ, Li X, Yu S, Zhao Y, Shen M, Zhu F, Wang X, Wang M, Balakrishnan A, Ott M, Peng F, Qin RY (2018) Let-7c inhibits cholangiocarcinoma growth but promotes tumor cell invasion and growth at extrahepatic sites. Cell Death & Disease 9(2): 249.

    2017

    • Akmatov MK, Jentsch L, Riese P, May M, Ahmed MW, Werner D, Rosel A, Prokein J, Bernemann I, Klopp N, Prochnow B, Illig T, Schindler C, Guzman CA, Pessler F (2017) Motivations for (non)participation in population-based health studies among the elderly - comparison of participants and nonparticipants of a prospective study on influenza vaccination. BMC Med Res Methodol 17(1): 18.

    • Akmatov MK, Koch N, Vital M, Ahrens W, Flesch-Janys D, Fricke J, Gatzemeier A, Greiser H, Günther K, Illig T, Kaaks R, Krone B, Kühn A, Linseisen J, Meisinger C, Michels K, Moebus S, Nieters A, Obi N, Schultze A, Six-Merker J, Pieper DH, Pessler F (2017) Determination of nasal and oropharyngeal microbiomes in a multicenter population-based study – findings from Pretest 1 of the German National Cohort. Sci Rep 7(1): 1855.

    • Akmatov MK, Riese P, May M, Jentsch L, Ahmed MW, Werner D, Rösel A, Tyler M, Pessler K, Prokein J, Bernemann I, Klopp N, Prochnow B, Trittel S, Tallam A, Illig T, Schindler C, Guzmán CA, Pessler F (2017) Establishment of a cohort for deep phenotyping of the immune response to influenza vaccination among elderly individuals recruited from the general population. Hum Vaccin Immunother 0 1-10.

    • Akmatov MK, Rober N, Ahrens W, Flesch-Janys D, Fricke J, Greiser H, Gunther K, Kaaks R, Kemmling Y, Krone B, Linseisen J, Meisinger C, Moebus S, Obi N, Guzman CA, Conrad K, Pessler F (2017) Anti-nuclear autoantibodies in the general German population: prevalence and lack of association with selected cardiovascular and metabolic disorders-findings of a multicenter population-based study. Arthritis Res Ther 19(1): 127.

    • Alissafi T, Banos A, Boon L, Sparwasser T, Ghigo A, Wing K, Vassilopoulos D, Boumpas D, Chavakis T, Cadwell K, Verginis P (2017) Tregs restrain dendritic cell autophagy to ameliorate autoimmunity. J Clin Invest 127(7): 2789-2804.

    • Anderton B, Camarda R, Balakrishnan S, Balakrishnan A, Kohnz RA, Lim L, Evason KJ, Momcilovic O, Kruttwig K, Huang Q, Xu G, Nomura DK, Goga A (2017) MYC -driven inhibition of the glutamate-cysteine ligase promotes glutathione depletion in liver cancer. EMBO Rep 18(4): 569-585.

    • Bankwitz D, Doepke M, Hueging K, Weller R, Bruening J, Behrendt P, Lee JY, Vondran FWR, Manns MP, Bartenschlager R, Pietschmann T (2017) Maturation of secreted HCV particles by incorporation of secreted apoE protects from antibodies by enhancing infectivity. J Hepatol 67(3): 480-489.

    • Bartenschlager R, Cornberg M, Pietschmann T (2017) Maßgeschneiderte Therapie der Virushepatitis der Gegenwart und Zukunft. Der Internist 58(7): 666-674.

    • Becker B, Bischoff B, Brill FHH, Steinmann E, Steinmann J (2017) Virucidal efficacy of a sonicated hydrogen peroxide system (trophon® EPR) following European and German test methods. GMS Hyg Infect Control 12:(n/a): Doc02.

    • Becker B, Brill FHH, Todt D, Steinmann E, Lenz J, Paulmann D, Bischoff B, Steinmann J (2017) Virucidal efficacy of peracetic acid for instrument disinfection. Antimicrob Resist Infect Control 6:(n/a): 114.

    • Behrendt P, Lüth S, Dammermann W, Drave S, Brown RJP, Todt D, Schnoor U, Steinmann E, Wedemeyer H, Pischke S, Iking-Konert C (2017) Exacerbation of hepatitis E virus infection during anti-TNFα treatment. Joint Bone Spine 84(2): 217-219.

    • Behrendt P, Perin P, Menzel N, Banda D, Pfaender S, Alves MP, Thiel V, Meulemann P, Colpitts CC, Schang LM, Vondran FWR, Anggakusuma, Manns MP, Steinmann E, Pietschmann T (2017) Pentagalloylglucose, a highly bioavailable polyphenolic compound present in Cortex moutan, efficiently blocks hepatitis C virus entry. Antiviral Res 147:(n/a): 19-28.

    • Bieber K, Sun S, Witte M, Kasprick A, Beltsiou F, Behnen M, Laskay T, Schulze FS, Pipi E, Reichhelm N, Pagel R, Zillikens D, Schmidt E, Sparwasser T, Kalies K, Ludwig RJ (2017) Regulatory T Cells Suppress Inflammation and Blistering in Pemphigoid Diseases. Front Immunol 8:(n/a): 1628.

    • Bohm K, Filomena A, Schneiderhan-Marra N, Krause G, Sievers C (2017) Validation of HAV biomarker 2A for differential diagnostic of hepatitis A infected and vaccinated individuals using multiplex serology. Vaccine 35(43): 5883--5889.

    • Bongartz H, Rübsamen N, Raupach-Rosin H, Akmatov MK, Mikolajczyk RT (2017) Why do people participate in health-related studies?. Int J Public Health 62(9): 1059-1062.

    • Borchers S, Babaei R, Klimpel C, Duque Escobar J, Schröder S, Blume R, Malik MNH, Oetjen E (2017) TNFalpha-induced DLK activation contributes to apoptosis in the beta-cell line HIT. Naunyn Schmiedebergs Arch Pharmacol 390(8): 813-825.

    • Bruening J, Weigel B, Gerold G (2017) The Role of Type III Interferons in Hepatitis C Virus Infection and Therapy. J Immunol Res 2017(n/a): 12.

    • Cimini E, Viola D, Cabeza-Cabrerizo M, Romanelli A, Tumino N, Sacchi A, Bordoni V, Casetti R, Turchi F, Martini F, Bore JA, Koundouno FR, Duraffour S, Michel J, Holm T, Zekeng EG, Cowley L, Garcia Dorival I, Doerrbecker J, Hetzelt N, Baum JHJ, Portmann J, Wölfel R, Gabriel M, Miranda O, Díaz G, Díaz JE, Fleites YA, Piñeiro CA, Castro CM, Koivogui L, Magassouba N, Diallo B, Ruibal P, Oestereich L, Wozniak DM, Lüdtke A, Becker-Ziaja B, Capobianchi MR, Ippolito G, Carroll MW, Günther S, Di Caro A, Muñoz-Fontela C, Agrati C (2017) Different features of Vδ2 T and NK cells in fatal and non-fatal human Ebola infections. PLoS Negl Trop Dis 11(5): 1-11.

    • De Jaime-Soguero A, Aulicino F, Ertaylan G, Griego A, Cerrato A, Tallam A, del Sol A, Cosma MP, Lluis F (2017) Wnt/Tcf1 pathway restricts embryonic stem cell cycle through activation of the Ink4/Arf locus. PLoS Genet 13(3): 1-27.

    • Doberenz S, Eckweiler D, Reichert O, Jensen V, Bunk B, Spröer C, Kordes A, Frangipani E, Luong K, Korlach J, Heeb S, Overmann J, Kaever V, Häussler S (2017) Identification of a Pseudomonas aeruginosa PAO1 DNA Methyltransferase, Its Targets, and Physiological Roles. mBio 8(1).

    • Ducroux A, Goffinet C (2017) cGAS, an antiviral weapon: role in the recognition of HIV-1 transmitted from cell to cell. Med Sci (Paris) 33(8-9): 732-734.

    • Filomena A, Pessler F, Akmatov MK, Krause G, Duffy D, Gärtner B, Gerhard M, Albert ML, Joos TO, Schneiderhan-Marra N (2017) Development of a Bead-Based Multiplex Assay for the Analysis of the Serological Response against the Six Pathogens HAV, HBV, HCV, CMV, T. gondii, and H. pylori. High-Throughput 6(4): 14.

    • Fischer JC, Bscheider M, Eisenkolb G, Lin CC, Wintges A, Otten V, Lindemans CA, Heidegger S, Rudelius M, Monette S, Porosnicu Rodriguez KA, Calafiore M, Liebermann S, Liu C, Lienenklaus S, Weiss S, Kalinke U, Ruland J, Peschel C, Shono Y, Docampo M, Velardi E, Jenq RR, Hanash AM, Dudakov JA, Haas T, van den Brink MRM, Poeck H (2017) RIG-I/MAVS and STING signaling promote gut integrity during irradiation- and immune-mediated tissue injury. Sci Transl Med 9(386).

    • Friedrich C, Mamareli P, Thiemann S, Kruse F, Wang Z, Holzmann B, Strowig T, Sparwasser T, Lochner M (2017) MyD88 signaling in dendritic cells and the intestinal epithelium controls immunity against intestinal infection with C. rodentium. PLOS Pathogens 13(5): 1-26.

    • Geis FK, Galla M, Hoffmann D, Kuehle J, Zychlinski D, Maetzig T, Schott JW, Schwarzer A, Goffinet C, Goff SP, Schambach A (2017) Potent and reversible lentiviral vector restriction in murine induced pluripotent stem cells. Retrovirology 14(1): 34.

    • Gerold G, Bruening J, Weigel B, Pietschmann T (2017) Protein interactions during the flavivirus and hepacivirus life cycle. Mol Cell Proteomics 16(4 suppl 1): S75-S91.

    • González-Motos V, Jürgens C, Ritter B, Kropp KA, Durán V, Larsen O, Binz A, Ouwendijk WJD, Lenac Rovis T, Jonjic S, Verjans GMGM, Sodeik B, Krey T, Bauerfeind R, Schulz TF, Kaufer BB, Kalinke U, Proudfoot AEI, Rosenkilde MM, Viejo-Borbolla A (2017) Varicella zoster virus glycoprotein C increases chemokine-mediated leukocyte migration. PLoS Pathog 13(5): 1-28.

    • Hinz T, Kallen K, Britten CM, Flamion B, Granzer U, Hoos A, Huber C, Khleif S, Kreiter S, Rammensee HG, Sahin U, Singh-Jasuja H, Tureci O, Kalinke U (2017) The European Regulatory Environment of RNA-Based Vaccines. Methods Mol Biol 1499(n/a): 203--222.

    • Hirche C, Frenz T, Haas SF, Doring M, Borst K, Tegtmeyer PK, Brizic I, Jordan S, Keyser K, Chhatbar C, Pronk E, Lin S, Messerle M, Jonjic S, Falk CS, Trumpp A, Essers MAG, Kalinke U (2017) Systemic Virus Infections Differentially Modulate Cell Cycle State and Functionality of Long-Term Hematopoietic Stem Cells In~Vivo. Cell Rep 19(11): 2345--2356.

    • Hoffmann M, Crone L, Dietzel E, Paijo J, Gonzalez-Hernandez M, Nehlmeier I, Kalinke U, Becker S, Pohlmann S (2017) A polymorphism within the internal fusion loop of the Ebola virus glycoprotein modulates host cell entry. J Virol 91(9).

    • Ivin M, Dumigan A, de Vasconcelos FN, Ebner F, Borroni M, Kavirayani A, Przybyszewska KN, Ingram RJ, Lienenklaus S, Kalinke U, Stoiber D, Bengoechea JA, Kovarik P (2017) Natural killer cell-intrinsic type I IFN signaling controls Klebsiella pneumoniae growth during lung infection. PLOS Pathog 13(11): 1-29.

    • Joean O, Hueber A, Feller F, Jirmo AC, Lochner M, Dittrich AM, Albrecht Melanie (2017) Suppression of Th17-polarized airway inflammation by rapamycin. Sci Rep 7(1): 15336.

    • Karabaev BB, Beisheeva NJ, Satybaldieva AB, Ismailova AD, Pessler F, Akmatov MK (2017) Seroprevalence of hepatitis B, hepatitis C, human immunodeficiency virus, Treponema pallidum, and co-infections among blood donors in Kyrgyzstan: a retrospective analysis (2013-2015). Infect Dis Poverty 6(1): 45.

    • Khera T, Todt D, Vercauteren K, McClure CP, Verhoye L, Farhoudi A, Bhuju S, Geffers R, Baumert TF, Steinmann E, Meuleman P, Pietschmann T, Brown RJP (2017) Tracking HCV protease population diversity during transmission and susceptibility of founder populations to antiviral therapy. Antiviral Research 139(n/a): 129 - 137.

    • Kindler E, Gil-Cruz C, Spanier J, Li Y, Wilhelm J, Rabouw HH, Züst R, Hwang M, V’kovski P, Stalder H, Marti S, Habjan M, Cervantes-Barragan L, Elliot R, Karl N, Gaughan C, van Kuppeveld FJM, Silverman RH, Keller M, Ludewig B, Bergmann CC, Ziebuhr J, Weiss SR, Kalinke U, Thiel V (2017) Early endonuclease-mediated evasion of RNA sensing ensures efficient coronavirus replication. PLoS Pathog 13(2): 1-26.

    • Kirchhoff L, Olsowski M, Zilmans K, Dittmer S, Haase G, Sedlacek L, Steinmann E, Buer J, Rath PM, Steinmann J (2017) Biofilm formation of the black yeast-like fungus Exophiala dermatitidis and its susceptibility to antiinfective agents. Sci Rep 7(n/a): 42886.

    • Kommerein N, Stumpp SN, Müsken M, Ehlert N, Winkel A, Häussler S, Behrens P, Buettner FFR, Stiesch M (2017) An oral multispecies biofilm model for high content screening applications. PLoS One 12(3): 1-21.

    • Krenn V, Perino G, Rüther W, Krenn VT, Huber M, Hügle T, Najm A, Müller S, Boettner F, Pessler F, Waldstein W, Kriegsmann J, Casadonte R, Häupl T, Wienert S, Krukemeyer MG, Sesselmann S, Sunitsch S, Tikhilov R, Morawietz L (2017) 15 years of the histopathological synovitis score, further development and review: A diagnostic score for rheumatology and orthopaedics. Pathol Res Pract 213(8): 874-881.

    • Lirussi D, Ebensen T, Schulze K, Trittel S, Duran V, Liebich I, Kalinke U, Guzman CA (2017) Type I IFN and not TNF, is Essential for Cyclic Di-nucleotide-elicited CTL by a Cytosolic Cross-presentation. EBioMedicine n/a(22): 100-111.

    • Matschulla T, Berry R, Gerke C, Döring M, Busch J, Paijo J, Kalinke U, Momburg F, Hengel H, Halenius A (2017) A highly conserved sequence of the viral TAP inhibitor ICP47 is required for freezing of the peptide transport cycle. Sci Rep 7(1): 2933.

    • Minarrieta L, Ghorbani P, Sparwasser T, Berod L (2017) Metabolites: deciphering the molecular language between DCs and their environment. Semin Immunopathol 39(2): 177-198.

    • Müsken M, Klimmek K, Sauer-Heilborn A, Donnert M, Sedlacek L, Suerbaum S, Häussler S (2017) Towards individualized diagnostics of biofilm-associated infections: a case study. npj Biofilms and Microbiomes 3:(n/a): 22.

    • Paijo J, Kaever V, Kalinke U (2017) cGAMP Quantification in Virus-Infected Human Monocyte-Derived Cells by HPLC-Coupled Tandem Mass Spectrometry. Methods Mol Biol n/a(1656): 153-166.

    • Pfaender S, Vielle NJ, Ebert N, Steinmann E, Alves MP, Thiel V (2017) Inactivation of Zika virus in human breast milk by prolonged storage or pasteurization. Virus Res 228(n/a): 58 - 60.

    • Pfaender S, Walter S, Grabski E, Todt D, Bruening J, Romero-Brey I, Gather T, Brown RJP, Hahn K, Puff C, Pfankuche VM, Hansmann F, Postel A, Becher P, Thiel V, Kalinke U, Wagner B, Bartenschlager R, Baumgärtner W, Feige K, Pietschmann T, Cavalleri JMV, Steinmann E (2017) Immune protection against reinfection with nonprimate hepacivirus. Proceedings of the National Academy of Sciences 114(12): E2430-E2439.

    • Pfaender S, Walter S, Grabski E, Todt D, Bruening J, Romero-Brey I, Gather T, Brown RJP, Hahn K, Puff C, Pfankuche VM, Hansmann F, Postel A, Becher P, Thiel V, Kalinke U, Wagner B, Bartenschlager R, Baumgärtner W, Feige K, Pietschmann T, Cavalleri JMV, Steinmann E (2017) Immune protection against reinfection with nonprimate hepacivirus. Proc Natl Acad Sci U S A 114(12): E2430-E2439.

    • Pietschmann T (2017) Clinically approved ion channel inhibitors close gates for hepatitis C virus and open doors for drug repurposing in infectious viral diseases. J Virol 91(2).

    • Popovic B, Golemac M, Podlech J, Zeleznjak J, Bilic-Zulle L, Lukic ML, Cicin-Sain L, Reddehase MJ, Sparwasser T, Krmpotic A, Jonjic S (2017) IL-33/ST2 pathway drives regulatory T cell dependent suppression of liver damage upon cytomegalovirus infection. PLoS Pathog 13(4): 1-23.

    • Preusse M, Schughart K, Pessler F (2017) Host Genetic Background Strongly Affects Pulmonary microRNA Expression before and during Influenza A Virus Infection. Front Immunol 8(n/a): 246.

    • Reichert C, Campe A, Walter S, Pfaender S, Welsch K, Ruddat I, Sieme H, Feige K, Steinmann E, Cavalleri JMV (2017) Frequent occurrence of nonprimate hepacivirus infections in Thoroughbred breeding horses - A cross-sectional study for the occurrence of infections and potential risk factors. Vet Microbiol 203(n/a): 315--322.

    • Ruangkiattikul N, Nerlich A, Abdissa K, Lienenklaus S, Suwandi A, Janze N, Laarmann K, Spanier J, Kalinke U, Weiss S, Goethe R (2017) cGAS-STING-TBK1-IRF3/7 Induced Interferon-β Contributes to the Clearing of Non Tuberculous Mycobacterial Infection in Mice. Virulence n/a(n/a): 1-13.

    • Rubsamen N, Akmatov MK, Castell S, Karch A, Mikolajczyk RT (2017) Factors associated with attrition in a longitudinal online study: results from the HaBIDS panel. BMC Med Res Methodol 17(1): 132.

    • Rubsamen N, Akmatov MK, Castell S, Karch A, Mikolajczyk RT (2017) Comparison of response patterns in different survey designs: a longitudinal panel with mixed-mode and online-only design. Emerg Themes Epidemiol 14(n/a): 4.

    • Schniederjans M, Koska M, Häussler S (2017) Transcriptional and mutational profiling of an aminoglycoside resistant Pseudomonas aeruginosa small colony variant. Antimicrobial Agents and Chemotherapy 61(11).

    • Seidel K, Balakrishnan A, Alexiou C, Janko C, Komoll RM, Wang LL, Kirschning A, Ott M (2017) Synthesis of Magnetic-Nanoparticle/Ansamitocin Conjugates—Inductive Heating Leads to Decreased Cell Proliferation In Vitro and Attenuation Of Tumour Growth In Vivo. Chemistry 23(50): 12326-12337.

    • Selvakumar TA, Bhushal S, Kalinke U, Wirth D, Hauser H, Köster M, Hornef MW (2017) Identification of a Predominantly Interferon-$\uplambda$-Induced Transcriptional Profile in Murine Intestinal Epithelial Cells. Front Immunol 8(n/a): 1302.

    • Sesti-Costa R, Françozo MCS, Silva GK, Proenca-Modena JL, Silva JS (2017) TLR3 is required for survival following Coxsackievirus B3 infection by driving T lymphocyte activation and polarization: The role of dendritic cells. PLoS One 12(10): 1-20.

    • Sgodda M, Dai Z, Zweigerdt R, Sharma AD, Ott M, Cantz T (2017) A Scalable Approach for the Generation of Human Pluripotent Stem Cell-Derived Hepatic Organoids with Sensitive Hepatotoxicity Features. Stem Cells and Development 26(20): 1490-1504.

    • Siddharta A, Pfaender S, Vielle NJ, Dijkman R, Friesland M, Becker B, Yang J, Engelmann M, Todt D, Windisch MP, Brill FH, Steinmann J, Steinmann J, Becker S, Alves MP, Pietschmann T, Eickmann M, Thiel V, Steinmann E (2017) Virucidal activity of WHO-recommended formulations against enveloped viruses including Zika, Ebola and emerging Coronaviruses. J Infect Dis 215(6): 902-906.

    • Speth MT, Repnik U, Müller E, Spanier J, Kalinke U, Corthay A, Griffiths G (2017) Poly(I:C)-Encapsulating Nanoparticles Enhance Innate Immune Responses to the Tuberculosis Vaccine Bacille Calmette–Guérin (BCG) via Synergistic Activation of Innate Immune Receptors. Mol Pharm 14(11): 4098-4112.

    • Tantawy MA, Nafie MS, Elmegeed GA, Ali IAI (2017) Auspicious role of the steroidal heterocyclic derivatives as a platform for anti-cancer drugs. Bioorg Chem 73(n/a): 128-146.

    • Tata M, Amman F, Pawar V, Wolfinger MT, Weiss S, Häussler S, Bläsi U (2017) The Anaerobically Induced sRNA PaiI Affects Denitrification in Pseudomonas aeruginosa PA14. Front Microbiol 8:(n/a): 2312.

    • Thiemann S, Smit N, Roy U, Lesker TR, Galvez EJC, Helmecke J, Basic M, Bleich A, Goodman AL, Kalinke U, Flavell RA, Erhardt M, Strowig T (2017) Enhancement of IFNgamma Production by Distinct Commensals Ameliorates Salmonella-Induced Disease. Cell Host Microbe 21(6): 682--694.e5.

    • Todt D, Schlevogt B, Deterding K, Grundhoff A, Manns MP, Wedemeyer H, Fischer N, Cornberg M, Steinmann E (2017) Successful retreatment of a patient with chronic hepatitis C genotype 2k/1b virus with ombitasvir/paritaprevir/ritonavir plus dasabuvir. J Antimicrob Chemother 72(5): 1541-1543.

    • Vasiliauskaite I, Owsianka A, England P, Khan AG, Cole S, Bankwitz D, Foung SKH, Pietschmann T, Marcotrigiano J, Rey FA, Patel AH, Krey T (2017) Conformational Flexibility in the Immunoglobulin-Like Domain of the Hepatitis C Virus Glycoprotein E2. mBio 8(3).

    • Walter S, Rasche A, Moreira-Soto A, Pfaender S, Bletsa M, Corman VM, Aguilar-Setien A, García-Lacy F, Hans A, Todt D, Schuler G, Shnaiderman-Torban A, Steinman A, Roncoroni C, Veneziano V, Rusenova N, Sandev N, Rusenov A, Zapryanova D, García-Bocanegra I, Jores J, Carluccio A, Veronesi MC, Cavalleri JMV, Drosten C, Lemey P, Steinmann E, Drexler JF (2017) Differential infection patterns and recent evolutionary origins of equine hepaciviruses in donkeys. J Virol 91(1).

    • Wang LL, Balakrishnan A, Bigall NC, Candito D, Miethe JF, Seidel K, Xie Y, Ott M, Kirschning A (2017) A Bio-Chemosynthetic Approach to Superparamagnetic Iron Oxide-Ansamitocin Conjugates for Use in Magnetic Drug Targeting. Chemistry 23(10): 2265-2270.

    • Weller R, Hueging K, Brown RJP, Todt D, Joecks S, Vondran FWR, Pietschmann T (2017) Hepatitis C virus strain-dependent usage of apolipoprotein E modulates assembly efficiency and specific infectivity of secreted virions. J Virol 91(18).

    • Zhao Y, Stepto H, Schneider CK (2017) Development of the First WHO Lentiviral Vector Standard: Towards the Production Control and Standardisation of Lentivirus based Gene Therapy Products. Hum Gene Ther Methods 28(4): 205-214.

    • Ziegler A, Soldner C, Lienenklaus S, Spanier J, Trittel S, Riese P, Kramps T, Weiss S, Heidenreich R, Jasny E, Guzman CA, Kallen KJ, Fotin-Mleczek M, Kalinke U (2017) A New RNA-Based Adjuvant Enhances Virus-Specific Vaccine Responses by Locally Triggering TLR- and RLH-Dependent Effects. J Immunol 198(4): 1595-1605.

    • Zischke J, Mamareli P, Pokoyski C, Gabaev I, Buyny S, Jacobs R, Falk CS, Lochner M, Sparwasser T, Schulz TF, Kay-Fedorov PC (2017) The human cytomegalovirus glycoprotein pUL11 acts via CD45 to induce T cell IL-10 secretion. PLoS Pathog 13(6): 1-26.

    • van Duuren JBJH, Musken M, Karge B, Tomasch J, Wittmann C, Haussler S, Bronstrup M (2017) Use of Single-Frequency Impedance Spectroscopy to Characterize the Growth Dynamics of Biofilm Formation in Pseudomonas aeruginosa. Sci Rep 7(1): 5223.

    • van der Vlugt L, Obieglo K, Ozir-Fazalalikhan A, Sparwasser T, Haeberlein S, Smits HH (2017) Schistosome-induced pulmonary B cells inhibit allergic airway inflammation and display a reduced Th2-driving function. Int J Parasitol 47(9): 545-554.

    2016

    • Abou-El-Enein M, Schneider CK (2016) Deciphering the EU clinical trials regulation. Nat Biotechnol 34(3): 231-233.

    • Akmatov MK, Stumme M, Pessler F (2016) Real-life practice of methotrexate toxicity monitoring in juvenile idiopathic arthritis in Germany, Switzerland and Austria: results of a cross-sectional assessment conducted in 2012. Clin Exp Rheumatol 34(3): 548-553.

    • Almeida L, Lochner M, Berod L, Sparwasser T (2016) Metabolic pathways in T cell activation and lineage differentiation. Semin Immunol 28(5): 514 - 524.

    • Andzinski L, Spanier J, Kasnitz N, Kröger A, Jin L, Brinkmann MM, Kalinke U, Weiss S, Jablonska J, Lienenklaus S (2016) Growing tumors induce a local STING dependent type I IFN response in dendritic cells. International Journal of Cancer 139(6): 1350-1357.

    • Anggakusuma, Brown RJ, Banda D, Todt D, Vieyres G, Steinmann E, Pietschmann T (2016) Hepaciviral NS3/4A proteases interfere with MAVS signalling of their cognate animal hosts and also with human MAVS: implications for zoonotic transmission. J Virol 90(23): 10670-10681.

    • Bankwitz D, Pietschmann T (2016) Hepatitis C virus plays hide and seek with neutralizing antibodies. Hepatology 64(6): 1840-1842.

    • Behrendt P, Bremer B, Todt D, Brown RJP, Heim A, Manns MP, Steinmann E, Wedemeyer H (2016) Hepatitis E Virus (HEV) ORF2 Antigen Levels Differentiate Between Acute and Chronic HEV Infection. J Infect Dis 214(3): 361-368.

    • Berod L, Sparwasser T (2016) pDCs Take a Deep Breath to Fight Viruses. Immunity 44(6): 1246-1248.

    • Binder SC, Eckweiler D, Schulz S, Bielecka A, Nicolai T, Franke R, Haussler S, Meyer-Hermann M (2016) Functional modules of sigma factor regulons guarantee adaptability and evolvability. Sci Rep 6:(n/a): 22212.

    • Blank T, Detje CN, Spiess A, Hagemeyer N, Brendecke SM, Wolfart J, Staszewski O, Zoller T, Papageorgiou I, Schneider J, Paricio-Montesinos R, Eisel UL, Manahan-Vaughan D, Jansen S, Lienenklaus S, Lu B, Imai Y, Muller M, Goelz SE, Baker DP, Schwaninger M, Kann O, Heikenwalder M, Kalinke U, Prinz M (2016) Brain Endothelial- and Epithelial-Specific Interferon Receptor Chain 1 Drives Virus-Induced Sickness Behavior and Cognitive Impairment. Immunity 44(4): 901-912.

    • Buettner M, Lochner M (2016) Development and Function of Secondary and Tertiary Lymphoid Organs in the Small Intestine and the Colon. Front Immunol 7:(n/a): 342.

    • Castiglia V, Piersigilli A, Ebner F, Janos M, Goldmann O, Dambock U, Kroger A, Weiss S, Knapp S, Jamieson AM, Kirschning C, Kalinke U, Strobl B, Muller M, Stoiber D, Lienenklaus S, Kovarik P (2016) Type I Interferon Signaling Prevents IL-1beta-Driven Lethal Systemic Hyperinflammation during Invasive Bacterial Infection of Soft Tissue. Cell Host Microbe 19(3): 375-387.

    • De Beuckelaer A, Pollard C, van Lint S, Roose K, van Hoecke L, Naessens T, Udhayakumar VK, Smet M, Sanders N, Lienenklaus S, Saelens X, Weiss S, Vanham G, Grooten J, De Koker S (2016) Type I Interferons Interfere with the Capacity of mRNA Lipoplex Vaccines to Elicit Cytolytic T Cell Responses. Mol Ther 24(11): 2012--2020.

    • Drave SA, Debing Y, Walter S, Todt D, Engelmann M, Friesland M, Wedemeyer H, Neyts J, Behrendt P, Steinmann E (2016) Extra-hepatic replication and infection of hepatitis E virus in neuronal-derived cells. Journal of Viral Hepatitis 23(7): 512-521.

    • Dudek M, Puttur F, Arnold-Schrauf C, Kuhl AA, Holzmann B, Henriques-Normark B, Berod L, Sparwasser T (2016) Lung epithelium and myeloid cells cooperate to clear acute pneumococcal infection. Mucosal Immunol 9(5): 1288-1302.

    • Elsaman AM, Muhammad EM, Pessler F (2016) Sonographic Findings in Gouty Arthritis: Diagnostic Value and Association with Disease Duration. Ultrasound Med Biol 42(6): 1330-1336.

    • Freitag J, Berod L, Kamradt T, Sparwasser T (2016) Immunometabolism and autoimmunity. Immunol Cell Biol 94(10): 925-934.

    • Frenz T, Grabski E, Buschjäger D, Vaas LAI, Burgdorf N, Schmidt RE, Witte T, Kalinke U (2016) CD4+ T cells in patients with chronic inflammatory rheumatic disorders show distinct levels of exhaustion. J Allergy Clin Immunol 138(2): 586-589 e10.

    • Gather T, Walter S, Pfaender S, Todt D, Feige K, Steinmann E, Cavalleri JM (2016) Acute and chronic infections with nonprimate hepacivirus in young horses. Vet Res 47(1): 97.

    • Gather T, Walter S, Todt D, Pfaender S, Brown RJ, Postel A, Becher P, Moritz A, Hansmann F, Baumgaertner W, Feige K, Steinmann E, Cavalleri JV (2016) Vertical transmission of hepatitis C virus-like nonprimate hepacivirus in horses. J Gen Virol 97(10): 2540-2551.

    • Gerold G, Bruening J, Pietschmann T (2016) Decoding protein networks during virus entry by quantitative proteomics. Virus Res 218(n/a): 25-39.

    • Ghanbari A, Dehghany J, Schwebs T, Musken M, Haussler S, Meyer-Hermann M (2016) Inoculation density and nutrient level determine the formation of mushroom-shaped structures in Pseudomonas aeruginosa biofilms. Sci Rep 6(n/a).

    • Goffinet C (2016) Cellular Antiviral Factors that Target Particle Infectivity of HIV-1. Curr HIV Res 14(3): 211-216.

    • Grine L, Steeland S, Van Ryckeghem S, Ballegeer M, Lienenklaus S, Weiss S, Sanders NN, Vandenbroucke RE, Libert C (2016) Topical imiquimod yields systemic effects due to unintended oral uptake. Sci Rep 6(n/a): 20134.

    • Heidrich B, Steinmann E, Plumeier I, Kirschner J, Sollik L, Ziegert S, Engelmann M, Lehmann P, Manns MP, Pieper DH, Wedemeyer H (2016) Frequent detection of HCV RNA and HCVcoreAg in stool of patients with chronic hepatitis C. J Clin Virol 80(n/a): 1 - 7.

    • Hendel N, Akmatov MK, Hamel J, Vogelberg C, Pessler F (2016) Exhaled breath analysis in childhood rheumatic disorders-a longitudinal study. J Breath Res 10(2): 021001.

    • Ionidis G, Hübscher J, Jack T, Becker B, Bischoff B, Todt D, Hodasa V, Brill FHH, Steinmann E, Steinmann J (2016) Development and virucidal activity of a novel alcohol-based hand disinfectant supplemented with urea and citric acid. BMC Infect Dis 16(1).

    • Khaledi A, Schniederjans M, Pohl S, Rainer R, Bodenhofer U, Xia B, Klawonn F, Bruchmann S, Preusse M, Eckweiler D, Dötsch A, Häussler S (2016) Transcriptome profiling of antimicrobial resistance in Pseudomonas aeruginosa. Antimicrob Agents and Chemother 66(8): 4722-4733.

    • Klotz U, Schmidt D, Willinger B, Steinmann E, Buer J, Rath PM, Steinmann J (2016) Echinocandin resistance and population structure of invasive Candida glabrata isolates from two university hospitals in Germany and Austria. Mycoses 59(5): 312-318.

    • Knuschke T, Rotan O, Bayer W, Sokolova V, Hansen W, Sparwasser T, Dittmer U, Epple M, Buer J, Westendorf AM (2016) Combination of nanoparticle-based therapeutic vaccination and transient ablation of regulatory T cells enhances anti-viral immunity during chronic retroviral infection. Retrovirology 13(1).

    • Kochs G, Anzaghe M, Kronhart S, Wagner V, Gogesch P, Scheu S, Lienenklaus S, Waibler Z (2016) In Vivo Conditions Enable IFNAR-Independent Type I Interferon Production by Peritoneal CD11b+ Cells upon Thogoto Virus Infection. J Virol 90(20): 9330-9337.

    • Krueger J, Pohl S, Preusse M, Kordes A, Rugen N, Schniederjans M, Pich A, Häussler S (2016) Unravelling post-transcriptional PrmC-dependent regulatory mechanisms in Pseudomonas aeruginosa. Environ Microbiol 18(10): 3583-3592.

    • Krull M, Klare I, Ross B, Trenschel R, Beelen DW, Todt D, Steinmann E, Buer J, Rath PM, Steinmann J (2016) Emergence of linezolid- and vancomycin-resistant Enterococcus faecium in a department for hematologic stem cell transplantation. Antimicrob Resist Infect Control 5(n/a): 31.

    • Kurhade C, Zegenhagen L, Weber E, Nair S, Michaelsen-Preusse K, Spanier J, Gekara NO, Kroger A, Overby AK (2016) Type I Interferon response in olfactory bulb, the site of tick-borne flavivirus accumulation, is primarily regulated by IPS-1. J Neuroinflammation 13(n/a): 22.

    • Lambricht L, Vanvarenberg K, De Beuckelaer A, Van Hoecke L, Grooten J, Ucakar B, Lipnik P, Sanders NN, Lienenklaus S, Preat V, Vandermeulen G (2016) Coadministration of a Plasmid Encoding HIV-1 Gag Enhances the Efficacy of Cancer DNA Vaccines. Mol Ther 24(9): 1686-1696.

    • Lorenz A, Pawar V, Häussler S, Weiss S (2016) Insights into host–pathogen interactions from state-of-the-art animal models of respiratory Pseudomonas aeruginosa infections. FEBS Letters 590(21): 3941-3959.

    • Luckoff A, Caramoy A, Scholz R, Prinz M, Kalinke U, Langmann T (2016) Interferon-beta signaling in retinal mononuclear phagocytes attenuates pathological neovascularization. EMBO Mol Med 8(6): 670-678.

    • Ludtke A, Ruibal P, Becker-Ziaja B, Rottstegge M, Wozniak DM, Cabeza-Cabrerizo M, Thorenz A, Weller R, Kerber R, Idoyaga J, Magassouba N, Gabriel M, Gunther S, Oestereich L, Munoz-Fontela C (2016) Ebola Virus Disease Is Characterized by Poor Activation and Reduced Levels of Circulating CD16+ Monocytes. J Infect Dis 214(suppl 3): S275-S280.

    • Maier BB, Hladik A, Lakovits K, Korosec A, Martins R, Kral JB, Mesteri I, Strobl B, Müller M, Kalinke U, Merad M, Knapp S (2016) Type I interferon promotes alveolar epithelial type II cell survival during pulmonary Streptococcus pneumoniae infection and sterile lung injury in mice. Eur J Immunol 46(9): 2175-2186.

    • Mehraj J, Witte W, Akmatov MK, Layer F, Werner G, Krause G (2016) Epidemiology of Staphylococcus aureus Nasal Carriage Patterns in the Community. 398(n/a): 55-87.

    • Mykicki N, Herrmann AM, Schwab N, Deenen R, Sparwasser T, Limmer A, Wachsmuth L, Klotz L, Kohrer K, Faber C, Wiendl H, Luger TA, Meuth SG, Loser K (2016) Melanocortin-1 receptor activation is neuroprotective in mouse models of neuroinflammatory disease. Sci Transl Med 8(362): 362ra146.

    • Namasivayam AA, Morales AF, Lacave AMF, Tallam A, Simovic B, Alfaro DG, Bobbili DR, Martin F, Androsova G, Shvydchenko I, Park J, Calvo JV, Hoeng J, Peitsch MC, Racero MGV, Biryukov M, Talikka M, Pérez MB, Rohatgi N, Díaz-Díaz N, Mandarapu R, Ruiz RA, Davidyan S, Narayanasamy S, Boue S, Guryanova S, Arbas SM, Menon S, Xiang Y (2016) Community-Reviewed Biological Network Models for Toxicology and Drug Discovery Applications. Gene Regul Syst Bio 10(n/a): 51-66.

    • Navarro S, Pickering DA, Ferreira IB, Jones L, Ryan S, Troy S, Leech A, Hotez PJ, Zhan B, Laha T, Prentice R, Sparwasser T, Croese J, Engwerda CR, Upham JW, Julia V, Giacomin PR, Loukas A (2016) Hookworm recombinant protein promotes regulatory T cell responses that suppress experimental asthma. Sci Transl Med 8(362): 362ra143.

    • Nuhn L, Vanparijs N, De Beuckelaer A, Lybaert L, Verstraete G, Deswarte K, Lienenklaus S, Shukla NM, Salyer ACD, Lambrecht BN, Grooten J, David SA, De Koker S, De Geest BG (2016) pH-degradable imidazoquinoline-ligated nanogels for lymph node-focused immune activation. Proceedings of the National Academy of Sciences 113(29): 8098-8103.

    • Paijo J, Döring M, Spanier J, Grabski E, Nooruzzaman M, Schmidt T, Witte G, Messerle M, Hornung V, Kaever V, Kalinke U (2016) cGAS Senses Human Cytomegalovirus and Induces Type I Interferon Responses in Human Monocyte-Derived Cells. PLoS Pathog 12(4): e1005546.

    • Perdicchio M, Ilarregui JM, Verstege MI, Cornelissen LAM, Schetters STT, Engels S, Ambrosini M, Kalay H, Veninga H, den Haan JMM, van Berkel LA, Samsom JN, Crocker PR, Sparwasser T, Berod L, Garcia-Vallejo JJ, van Kooyk Y, Unger WWJ (2016) Sialic acid-modified antigens impose tolerance via inhibition of T-cell proliferation and de novo induction of regulatory T cells. Proc Natl Acad Sci U S A 113(12): 3329-3334.

    • Perin PM, Haid S, Brown RJP, Doerrbecker J, Schulze K, Zeilinger C, von Schaewen M, Heller B, Vercauteren K, Luxenburger E, Baktash YM, Vondran FWR, Speerstra S, Awadh A, Mukhtarov F, Schang LM, Kirschning A, Müller R, Guzman CA, Kaderali L, Randall G, Meuleman P, Ploss A, Pietschmann T (2016) Flunarizine prevents hepatitis C virus membrane fusion in a genotype-dependent manner by targeting the potential fusion peptide within E1. Hepatology 63(1): 49--62.

    • Peschke K, Achleitner M, Frenzel K, Gerbaulet A, Ada SR, Zeller N, Lienenklaus S, Lesche M, Poulet C, Naumann R, Dahl A, Ravens U, Gunther C, Muller W, Knobeloch KP, Prinz M, Roers A, Behrendt R (2016) Loss of Trex1 in Dendritic Cells Is Sufficient To Trigger Systemic Autoimmunity. J Immunol 197(6): 2157-2166.

    • Pfaender S, Grabski E, Detje CN, Riebesehl N, Lienenklaus S, Steinmann E, Kalinke U, Pietschmann T (2016) Hepatitis C Virus Stimulates Murine CD8alpha-Like Dendritic Cells to Produce Type I Interferon in a TRIF-Dependent Manner. PLoS Pathog 12(7): e1005736.

    • Pfaender S, Grabski E, Detje CN, Riebesehl N, Lienenklaus S, Steinmann E, Kalinke U, Pietschmann T (2016) Hepatitis C Virus Stimulates Murine CD8alpha-Like Dendritic Cells to Produce Type I Interferon in a TRIF-Dependent Manner. PLoS Pathog 12(7): e1005736.

    • Pfaender S, von Hahn T, Steinmann J, Ciesek S, Steinmann E (2016) Prevention strategies for blood-borne viruses—in the Era of vaccines, direct acting antivirals and antiretroviral therapy. Rev Med Virol 26(5): 330-339.

    • Postel A, Cavalleri JM, Pfaender S, Walter S, Steinmann E, Fischer N, Feige K, Haas L, Becher P (2016) Frequent presence of hepaci and pegiviruses in commercial equine serum pools. Vet Microbiol 182(n/a): 8 - 14.

    • Puttur F, Francozo M, Solmaz G, Bueno C, Lindenberg M, Gohmert M, Swallow M, Tufa D, Jacobs R, Lienenklaus S, Kühl A A, Borkner L, Cicin-Sain L, Holzmann B, Wagner H, Berod L, Sparwasser T (2016) Conventional Dendritic Cells Confer Protection against Mouse Cytomegalovirus Infection via \TLR9\ and MyD88 Signaling. Cell Reports 17(4): 1113 - 1127.

    • Puttur F, Francozo M, Solmaz G, Bueno C, Lindenberg M, Gohmert M, Swallow M, Tufa D, Jacobs R, Lienenklaus S, Kühl A A, Borkner L, Cicin-Sain L, Holzmann B, Wagner H, Berod L, Sparwasser T (2016) Conventional Dendritic Cells Confer Protection against Mouse Cytomegalovirus Infection via TLR9 and MyD88 Signaling. Cell Rep 17(4): 1113 - 1127.

    • Raha S, Raud B, Oberdörfer L, Castro CN, Schreder A, Freitag J, Longerich T, Lochner M, Sparwasser T, Berod L, Koenecke C, Prinz I (2016) Disruption of de novo fatty acid synthesis via acetyl-CoA carboxylase 1 inhibition prevents acute graft-versus-host disease. Eur J Immunol 46(9): 2233-2238.

    • Ruibal P, Oestereich L, Lüdtke A, Becker-Ziaja B, Wozniak DM, Kerber R, Korva M, Cabeza-Cabrerizo M, Bore JA, Koundouno FR, Duraffour S, Weller R, Thorenz A, Cimini E, Viola D, Agrati C, Repits J, Afrough B, Cowley LA, Ngabo D, Hinzmann J, Mertens M, Vitoriano I, Logue CH, Boettcher JP, Pallasch E, Sachse A, Bah A, Nitzsche K, Kuisma E, Michel J, Holm T, Zekeng EG, Garcia-Dorival I, Wolfel R, Stoecker K, Fleischmann E, Strecker T, Di Caro A, Avsic-Zupanc T, Kurth A, Meschi S, Mely S, Newman E, Bocquin A, Kis Z, Kelterbaum A, Molkenthin P, Carletti F, Portmann J, Wolff S, Castilletti C, Schudt G, Fizet A, Ottowell LJ, Herker E, Jacobs T, Kretschmer B, Severi E, Ouedraogo N, Lago M, Negredo A, Franco L, Anda P, Schmiedel S, Kreuels B, Wichmann D, Addo MM, Lohse AW, De Clerck H, Nanclares C, Jonckheere S, Van Herp M, Sprecher A, Xiaojiang G, Carrington M, Miranda O, Castro CM, Gabriel M, Drury P, Formenty P, Diallo B, Koivogui L, Magassouba N, Carroll MW, Gunther S, Munoz-Fontela C (2016) Unique human immune signature of Ebola virus disease in Guinea. Nature 533(7601): 100-104.

    • Samir M, Pessler F (2016) Small Non-coding RNAs Associated with Viral Infectious Diseases of Veterinary Importance: Potential Clinical Applications. Front. Vet. Sci. 3(n/a): 22.

    • Samir M, Vaas LAI, Pessler F (2016) MicroRNAs in the Host Response to Viral Infections of Veterinary Importance. Front Vet Sci 3(n/a): 86.

    • Schlett CL, Hendel T, Hirsch J, Weckbach S, Caspers S, Schulz-Menger J, Ittermann T, von Knobelsdorff-Brenkenhoff F, Ladd SC, Moebus S, Stroszczynski C, Fischer B, Leitzmann M, Kuhl C, Pessler F, Hartung D, Kemmling Y, Hetterich H, Amunts K, Günther M, Wacker F, Rummeny E, Kauczor HU, Forsting M, Völzke H, Hosten N, Reiser MF, Bamberg F (2016) Quantitative, Organ-Specific Interscanner and Intrascanner Variability for 3 T Whole-Body Magnetic Resonance Imaging in a Multicenter, Multivendor Study. Invest Radiol 51(4): 255-265.

    • Schweitzer A, Pessler F, Akmatov MK (2016) Impact of rotavirus vaccination on coverage and timing of pentavalent vaccination – Experience from 2 Latin American countries. Human Vaccines & Immunotherapeutics 0 1-7.

    • Siddharta A, Pfaender S, Malassa A, Doerrbecker J, Anggakusuma, Engelmann M, Nugraha B, Steinmann J, Todt D, Vondran FW, Mateu-Gelabert P, Goffinet C, Steinmann E (2016) Inactivation of HCV and HIV by microwave: a novel approach for prevention of virus transmission among people who inject drugs. Sci Rep 6(n/a): 36619.

    • Smith KA, Filbey KJ, Reynolds LA, Hewitson JP, Harcus Y, Boon L, Sparwasser T, Hammerling G, Maizels RM (2016) Low-level regulatory T-cell activity is essential for functional type-2 effector immunity to expel gastrointestinal helminths. Mucosal Immunol 9(2): 428-443.

    • Song G, Pacher M, Balakrishnan A, Yuan Q, Tsay HC, Yang D, Reetz J, Brandes S, Dai Z, Pützer B M, Araúzo-Bravo M J, Steinemann D, Luedde T, Schwabe R F, Manns M P, Schöler H R, Schambach A, Cantz T, Ott M, Sharma A D (2016) Direct Reprogramming of Hepatic Myofibroblasts into Hepatocytes In Vivo Attenuates Liver Fibrosis. Cell Stem Cell 18(6): 797-808.

    • Stohr S, Costa R, Sandmann L, Westhaus S, Pfaender S, Anggakusuma, Dazert E, Meuleman P, Vondran FW, Manns MP, Steinmann E, von Hahn T, Ciesek S (2016) Host cell mTORC1 is required for HCV RNA replication. Gut 65(12): 2017-2028.

    • Tata M, Wolfinger MT, Amman F, Roschanski N, Dötsch A, Sonnleitner E, Häussler S, Bläsi U (2016) RNASeq Based Transcriptional Profiling of Pseudomonas aeruginosa PA14 after Short- and Long-Term Anoxic Cultivation in Synthetic Cystic Fibrosis Sputum Medium. PLoS One 11(1): e0147811.

    • Todt D, Gisa A, Radonic A, Nitsche A, Behrendt P, Suneetha PV, Pischke S, Bremer B, Brown RJP, Manns MP, Cornberg M, Bock CT, Steinmann E, Wedemeyer H (2016) In vivo evidence for ribavirin-induced mutagenesis of the hepatitis E virus genome. Gut 65(10): 1733-1743.

    • Todt D, Walter S, Brown RJP, Steinmann E (2016) Mutagenic Effects of Ribavirin on Hepatitis E Virus—Viral Extinction versus Selection of Fitness-Enhancing Mutations. Viruses 8(10): 283.

    • Todt D., Francois C., Kusuma A, Behrendt P, Engelmann M, Knegendorf L, Vieyres G, Wedemeyer H, Hartmann R, Pietschmann T, Duverlie G, Steinmann E (2016) Antiviral activity of different interferon (sub-) types against hepatitis E virus replication. Antimicrobial Agents and Chemotherapy 60(4): 2132-2139.

    • Vercauteren K, Brown RJ, Mesalam AA, Doerrbecker J, Bhuju S, Geffers R, Van Den Eede N, McClure CP, Troise F, Verhoye L, Baumert T, Farhoudi A, Cortese R, Ball JK, Leroux-Roels G, Pietschmann T, Nicosia A, Meuleman P (2016) Targeting a host-cell entry factor barricades antiviral-resistant HCV variants from on-therapy breakthrough in human-liver mice. Gut 65(12): 2029-2034.

    • Vieyres G, Welsch K, Gerold G, Gentzsch J, Kahl S, Vondran FWR, Kaderali L, Pietschmann T (2016) ABHD5/CGI-58, the Chanarin-Dorfman Syndrome Protein, Mobilises Lipid Stores for Hepatitis C Virus Production. PLoS Pathog 12(4): e1005568.

    • Walter S, Bollenbach A, Doerrbecker J, Pfaender S, Brown RJP, Vieyres G, Scott C, Foster R, Kumar A, Zitzmann N, Griffin S, Penin F, Pietschmann T, Steinmann E (2016) Ion-channel function and cross-species determinants in viral assembly of nonprimate hepacivirus p7. J Virol 90(10): 5075-5089.

    • Weissmuller S, Kronhart S, Kreuz D, Schnierle B, Kalinke U, Kirberg J, Hanschmann KM, Waibler Z (2016) TGN1412 Induces Lymphopenia and Human Cytokine Release in a Humanized Mouse Model. PLoS One 11(3): e0149093.

    • Weller R, Todt D, Engelmann M, Friesland M, Wedemeyer H, Pietschmann T, Steinmann E (2016) Apolipoprotein E polymorphisms and their protective effect on Hepatitis E virus replication. Hepatology 64(6): 2274-2276.

    • Win SJ, Kühl AA, Sparwasser T, Hünig T, Kamradt T (2016) In vivo activation of Treg cells with a CD28 superagonist prevents and ameliorates chronic destructive arthritis in mice. Eur J Immunol 46(5): 1193-1202.

    • Xu S, Ducroux A, Ponnurangam A, Vieyres G, Franz S, Müsken M, Zillinger T, Malassa A, Ewald E, Hornung V, Barchet W, Häussler S, Pietschmann T, Goffinet C (2016) cGAS-Mediated Innate Immunity Spreads Intercellularly through HIV-1 Env-Induced Membrane Fusion Sites. Cell Host & Microbe 20(4): 443-457.

    • Xu S, Ducroux A, Ponnurangam A, Vieyres G, Franz S, Müsken M, Zillinger T, Malassa A, Ewald E, Hornung V, Barchet W, Häussler S, Pietschmann T, Goffinet C (2016) cGAS-Mediated Innate Immunity Spreads Intercellularly through HIV-1 Env-Induced Membrane Fusion Sites. Cell Host & Microbe 20(4): 443 - 457.

    • Yang BH, Hagemann S, Mamareli P, Lauer U, Hoffmann U, Beckstette M, Föhse L, Prinz I, Pezoldt J, Suerbaum S, Sparwasser T, Hamann A, Floess S, Huehn J, Lochner M (2016) Foxp3 T cells expressing RORgammat represent a stable regulatory T-cell effector lineage with enhanced suppressive capacity during intestinal inflammation. Mucosal Immunol 9(2): 444-457.

    • Yang D, Yuan Q, Balakrishnan A, Bantel H, Klusmann JH, Manns MP, Ott M, Cantz T, Sharma AD (2016) MicroRNA-125b-5p mimic inhibits acute liver failure. Nat Commun 7(n/a): 11916.

    • de Araujo LS, Vaas LA, Ribeiro-Alves M, Geffers R, Mello FC, de Almeida AS, Moreira AD, Kritski AL, Lapa E.SilvaJR, Moraes MO, Pessler F, Saad MH (2016) Transcriptomic Biomarkers for Tuberculosis: Evaluation of DOCK9. EPHA4, and NPC2 mRNA Expression in Peripheral Blood. Front Microbiol 7(n/a): 1586.

    • von Schaewen M, Dorner M, Hueging K, Foquet L, Gerges S, Hrebikova G, Heller B, Bitzegeio J, Doerrbecker J, Horwitz JA, Gerold G, Suerbaum S, Rice CM, Meuleman P, Pietschmann T, Ploss A (2016) Expanding the Host Range of Hepatitis C Virus through Viral Adaptation. MBio 7(6).

    2015

    • Abd-Elshafy DN, Muller-Ladner U, Neumann E, Anggakusuma., Bahgat MM, Pessler F, Behrendt P (2015) Cell culture-derived HCV cannot infect synovial fibroblasts. Sci Rep 5(n/a): 18043.

    • Abd-Elshafy DN, Muller-Ladner U, Neumann E, Anggakusuma., Bahgat MM, Pessler F, Behrendt P (2015) Erratum: Cell culture-derived HCV cannot infect synovial fibroblasts. Sci Rep 6(n/a): 21441.

    • Abd-Elshafy DN, Pietschmann T, Muller-Ladner U, Neumann E, Anggakusuma, M BahgatM, Pessler F, Behrendt P (2015) Cell culture-derived HCV cannot infect synovial fibroblasts. Sci Rep 5(n/a): 18043.

    • Akeus P, Langenes V, Kristensen J, von Mentzer A, Sparwasser T, Raghavan S, Quiding-Jarbrink M (2015) Treg-cell depletion promotes chemokine production and accumulation of CXCR3 conventional T cells in intestinal tumors. Eur J Immunol 45(6): 1654-1666.

    • Akmatov MK, Kimani-Murage E, Pessler F, Guzman CA, Krause G, Kreienbrock L, Mikolajczyk RT (2015) Evaluation of invalid vaccine doses in 31 countries of the WHO African Region. Vaccine 33(7): 892-901.

    • Akmatov MK, Rubsamen N, Schultze A, Kemmling Y, Obi N, Gunther K, Ahrens W, Pessler F, Krause G, Mikolajczyk RT (2015) Diverse recruitment strategies result in different participation percentages in a web-based study, but in similar compliance. Int J Public Health 60(8): 937-943.

    • Alissafi T, Hatzioannou A, Ioannou M, Sparwasser T, Grun JR, Grutzkau A, Verginis P (2015) De Novo-Induced Self-Antigen-Specific Foxp3+ Regulatory T Cells Impair the Accumulation of Inflammatory Dendritic Cells in Draining Lymph Nodes. J Immunol 194(12): 5812-5824.

    • Anggakusuma, Frentzen A, Gurlevik E, Yuan Q, Steinmann E, Ott M, Staeheli P, Hornung V, Kuehnel F, Pietschmann T (2015) Control of HCV replication in mouse liver derived cells by MAVS-dependent production of type-I and -III interferons. J Virol 89(7): 3833-3845.

    • Anggakusuma, Frentzen A, Gurlevik E, Yuan Q, Steinmann E, Ott M, Staeheli P, Hornung V, Kuehnel F, Pietschmann T (2015) Control of HCV replication in mouse liver derived cells by MAVS-dependent production of type-I and -III interferons. J Virol 98(7): 3833-3845.

    • Annemann M, Wang Z, Plaza-Sirvent C, Glauben R, Schuster M, Ewald Sander F, Mamareli P, Kuhl AA, Siegmund B, Lochner M, Schmitz I (2015) IkappaBNS Regulates Murine Th17 Differentiation during Gut Inflammation and Infection. J Immunol 194(6): 2888-2898.

    • Arnold-Schrauf C, Berod L, Sparwasser T (2015) Dendritic cell-specific targeting of MyD88 signalling pathways in vivo. Eur J Immunol 45(1): 32-39.

    • Bielecki P, Jensen V, Schulze W, Godeke J, Strehmel J, Eckweiler D, Nicolai T, Bielecka A, Wille T, Gerlach RG, Haussler S (2015) Cross talk between the response regulators PhoB and TctD allows for the integration of diverse environmental signals in Pseudomonas aeruginosa. Nucleic Acids Res 43(13): 6413-6425.

    • Blanka A, Duvel J, Dotsch A, Klinkert B, Abraham WR, Kaever V, Ritter C, Narberhaus F, Haussler S (2015) Constitutive production of c-di-GMP is associated with mutations in a variant of Pseudomonas aeruginosa with altered membrane composition. Sci Signal 8(372): ra36.

    • Bolton HA, Zhu E, Terry AM, Guy TV, Koh WP, Tan SY, Power CA, Bertolino P, Lahl K, Sparwasser T, Shklovskaya E, de St. Groth BF (2015) Selective Treg reconstitution during lymphopenia normalizes DC costimulation and prevents graft-versus-host disease. J Clin Invest 125(9): 3627-3641.

    • Brinkmann MM, Dag F, Hengel H, Messerle M, Kalinke U, Cicin-Sain L (2015) Cytomegalovirus immune evasion of myeloid lineage cells. Med Microbiol Immunol 204(3): 367-382.

    • Bruchmann S, Muthukumarasamy U, Pohl S, Preusse M, Bielecka A, Nicolai T, Hamann I, Hillert R, Kola A, Gastmeier P, Eckweiler D, Haussler S (2015) Deep transcriptome profiling of clinical Klebsiella pneumoniae isolates reveals strain- and sequence type-specific adaptation. Environ Microbiol 17(11): 4690-4710.

    • Buettner M, Dittrich-Breiholz O, Falk CS, Lochner M, Smoczek A, Menzel F, Bornemann M, Bode U (2015) Stromal cells as trend-setters for cells migrating into the lymph node. Mucosal Immunol 8(3): 640-649.

    • Casilag F, Lorenz A, Krüger J, Klawonn F, Weiss S, Häussler S (2015) The LasB elastase of Pseudomonas aeruginosa acts in concert with alkaline protease AprA to prevent flagellin-mediated immune recognition. Infect Immun 84(1): 162-171.

    • Castro CN, Freitag J, Berod L, Lochner M, Sparwasser T (2015) Microbe-associated immunomodulatory metabolites: Influence on T cell fate and function. Mol Immunol 68(2 Pt C): 575-584.

    • Crouse J, Kalinke U, Oxenius A (2015) Regulation of antiviral T cell responses by type I interferons. Nat Rev Immunol 15(4): 231-242.

    • Detje CN, Lienenklaus S, Chhatbar C, Spanier J, Prajeeth CK, Soldner C, Tovey MG, Schluter D, Weiss S, Stangel M, Kalinke U (2015) Upon intranasal VSV infection astrocytes in the olfactory bulb are important IFN-beta producers that protect from lethal encephalitis. J Virol 89(5): 2731-2738.

    • Dhainaut M, Coquerelle C, Uzureau S, Denoeud J, Acolty V, Oldenhove G, Galuppo A, Sparwasser T, Thielemans K, Pays E, Yagita H, Borst J, Moser M (2015) Thymus-derived regulatory T cells restrain pro-inflammatory Th1 responses by downregulating CD70 on dendritic cells. EMBO J 34(10): 1336-1348.

    • Dotsch A, Schniederjans M, Khaledi A, Hornischer K, Schulz S, Bielecka A, Eckweiler D, Pohl S, Haussler S (2015) The Pseudomonas aeruginosa Transcriptional Landscape Is Shaped by Environmental Heterogeneity and Genetic Variation. MBio 6(4): e00749.

    • Düvel J, Bense S, Möller S, Bertinetti D, Schwede F, Morr M, Eckweiler D, Genieser HG, Jänsch Lothar, Herberg FriedrichW., Frank Ronald, Häussler Susanne (2015) Application of synthetic peptide arrays to uncover c-di-GMP binding motifs. Journal of Bacteriology 198(1): 138-146.

    • Fischbach H, Doring M, Nikles D, Lehnert E, Baldauf C, Kalinke U, Tampe R (2015) Ultrasensitive quantification of TAP-dependent antigen compartmentalization in scarce primary immune cell subsets. Nat Commun 6(n/a): 6199.

    • Frenz T, Grabski E, Duran V, Hozsa C, Stepczynska A, Furch M, Gieseler RK, Kalinke U (2015) Antigen presenting cell-selective drug delivery by glycan-decorated nanocarriers. Eur J Pharm Biopharm 97(Pt A): 13-17.

    • Garcia-Risco MR, Vazquez E, Sheldon J, Steinmann E, Riebesehl N, Fornari T, Reglero G (2015) Supercritical fluid extraction of heather (Calluna vulgaris) and evaluation of anti-hepatitis C virus activity of the extracts. Virus Res 198(n/a): 9-14.

    • Gerold G, Meissner F, Bruening J, Welsch K, Perin PM, Baumert TF, Vondran FW, Kaderali L, Marcotrigiano J, Khan AG, Mann M, Rice CM, Pietschmann T (2015) Quantitative Proteomics Identifies Serum Response Factor Binding Protein 1 as a Host Factor for Hepatitis C Virus Entry. Cell Rep 12(5): 864-878.

    • Ghorbani P, Santhakumar P, Hu Q, Djiadeu P, Wolever TM, Palaniyar N, Grasemann H (2015) Short-chain fatty acids affect cystic fibrosis airway inflammation and bacterial growth. Eur Respir J 46(4): 1033-45.

    • Grabski E, Wappler I, Pfaender S, Steinmann E, Haid S, Dzionek A, Pietschmann T, Kalinke U (2015) Efficient virus assembly, but not infectivity, determines the magnitude of hepatitis C virus induced interferon-alpha responses of plasmacytoid dendritic cells. J Virol 89(6): 3200-3208.

    • Grabski E, Wappler I, Pfaender S, Steinmann E, Haid S, Dzionek A, Pietschmann T, Kalinke U (2015) Efficient virus assembly, but not infectivity, determines the magnitude of hepatitis C virus induced interferon-alpha responses of plasmacytoid dendritic cells. J Virol 89(6): 3200-3208.

    • Haid S, Grethe C, Bankwitz D, Grunwald T, Pietschmann T (2015) Identification of a human respiratory syncytial virus (hRSV) cell entry inhibitor by using a novel lentiviral pseudotype (hRSVpp) system. J Virol 90(6): 3065-3073.

    • Hedenstierna M, Weiland O, Brass A, Bankwitz D, Behrendt P, Uhnoo I, Aleman S, Cardell K, Fryden A, Norkrans G, Eilard A, Glaumann H, Pietschmann T, Sallberg M, Brenndorfer ED (2015) Long-term follow-up of successful hepatitis C virus therapy: waning immune responses and disappearance of liver disease are consistent with cure. Aliment Pharmacol Ther 41(6): 532-543.

    • Hueging K, Weller R, Doepke M, Vieyres G, Todt D, Wolk B, Vondran FW, Geffers R, Lauber C, Kaderali L, Penin F, Pietschmann T (2015) Several Human Liver Cell Expressed Apolipoproteins Complement HCV Virus Production with Varying Efficacy Conferring Differential Specific Infectivity to Released Viruses. PLoS One 10(7): e0134529.

    • Junge N, Mingozzi F, Ott M, Baumann U (2015) Adeno-associated Virus Vector Based Gene Therapy for Monogenetic Metabolic Diseases of the Liver. J Pediatr Gastroenterol Nutr 60(4): 433-440.

    • Khan AR, Amu S, Saunders SP, Hams E, Blackshields G, Leonard MO, Weaver CT, Sparwasser T, Sheils O, Fallon PG (2015) Ligation of TLR7 on CD19 CD1d B cells suppresses allergic lung inflammation via regulatory T cells. Eur J Immunol 45(6): 1842-1854.

    • Khan AR, Hams E, Floudas A, Sparwasser T, Weaver CT, Fallon PG (2015) PD-L1(hi) B cells are critical regulators of humoral immunity. Nat Commun 6:(n/a): 5997.

    • Koutsoudakis G, Romero-Brey I, Berger C, Perez-Vilaro G, Perin PM, Vondran FW, Kalesse M, Harmrolfs K, Muller R, Martinez JP, Pietschmann T, Bartenschlager R, Bronstrup M, Meyerhans A, Diez J (2015) Soraphen A: a broad-spectrum antiviral natural product with potent anti-hepatitis C virus activity. J Hepatol 63(4): 813-821.

    • Kusuma A, Romero-Brey I, Berger C, Colpitts CC, Boldanova T, Engelmann M, Todt D, Perin PM, Behrendt P, Vondran FW, Xu S, Goffinet C, Schang LM, Heim MH, Bartenschlager R, Pietschmann T, Steinmann E (2015) Interferon-inducible cholesterol-25-hydroxylase restricts hepatitis C virus replication via blockage of membranous web formation. Hepatology 62(3): 702-714.

    • Lassak J, Keilhauer E, Furst M, Wuichet K, Godeke J, Starosta AL, Chen JM, Sogaard-Andersen L, Rohr J, Wilson DN, Haussler S, Mann M, Jung K (2015) Arginine-rhamnosylation as new strategy to activate translation elongation factor P. Nat Chem Biol 11(4): 266-270.

    • Lauber C, Vieyres G, Terczynska-Dyla E, Anggakusuma, Dijkman R, Gad HH, Akhtar H, Geffers R, Vondran FW, Thiel V, Kaderali L, Pietschmann T, Hartmann R (2015) Transcriptome analysis reveals a classical interferon signature induced by IFNlambda4 in human primary cells. Genes Immun 16(6): 414-421.

    • Legoux FP, Lim JB, Cauley A W, Dikiy S, Ertelt J, Mariani TJ, Sparwasser T, Way S S, Moon JJ (2015) CD4+ T Cell Tolerance to Tissue-Restricted Self Antigens Is Mediated by Antigen-Specific Regulatory T Cells Rather Than Deletion. Immunity 43(5): 896 - 908.

    • Lochner M, Berod L, Sparwasser T (2015) Fatty acid metabolism in the regulation of T cell function. Trends Immunol 36(2): 81-91.

    • Lochner M, Wang Z, Sparwasser T (2015) Chapter Five - The Special Relationship in the Development and Function of T Helper 17 and Regulatory T Cells. 136:(n/a): 99 - 129.

    • Luciani F, Galluzzo S, Gaggioli A, Kruse NA, Venneugues P, Schneider CK, Pini C, Melchiorri D (2015) Implementing quality by design for biotech products: are regulators on track?. MAbs 7(3): 451-455.

    • Lump E, Castellano LM, Meier C, Seeliger J, Erwin N, Sperlich B, Sturzel CM, Usmani S, Hammond RM, von Einem J, Gerold G, Kreppel F, Bravo-Rodriguez K, Pietschmann T, Holmes VM, Palesch D, Zirafi O, Weissman D, Sowislok A, Wettig B, Heid C, Kirchhoff F, Weil T, Klarner FG, Schrader T, Bitan G, Sanchez-Garcia E, Winter R, Shorter J, Munch J (2015) A molecular tweezer antagonizes seminal amyloids and HIV infection. Elife 4(n/a).

    • Mahapatra S, Albrecht M, Baru AM, Sparwasser T, Herrick C, Dittrich AM (2015) Superior Suppressive Capacity of Skin Tregs Compared to Lung Tregs in a Model of Epicutaneous Priming. J Invest Dermatol 135(10): 2418-2426.

    • Malczyk AH, Kupke A, Prufer S, Scheuplein VA, Hutzler S, Kreuz D, Beissert T, Bauer S, Hubich-Rau S, Tondera C, Shams Eldin H, Schmidt J, Vergara-Alert J, Suzer Y, Seifried J, Hanschmann KM, Kalinke U, Herold S, Sahin U, Cichutek K, Waibler Z, Eickmann M, Becker S, Muhlebach MD (2015) A highly immunogenic and protective MERS-Coronavirus vaccine based on recombinant MV vaccine platform. J Virol 89(22): 11654-11667.

    • Mobus S, Yang D, Yuan Q, Ludtke TH, Balakrishnan A, Sgodda M, Rani B, Kispert A, Arauzo-Bravo MJ, Vogel A, Manns MP, Ott M, Cantz T, Sharma AD (2015) MicroRNA-199a-5p inhibition enhances the liver repopulation ability of human embryonic stem cell-derived hepatic cells. J Hepatol 62(1): 101-110.

    • Molina MA, Diaz AM, Hesse C, Ginter W, Gentilini MV, Nunez GG, Canellada AM, Sparwasser T, Berod L, Castro MS, Manghi MA (2015) Immunostimulatory Effects Triggered by Enterococcus faecalis CECT7121 Probiotic Strain Involve Activation of Dendritic Cells and Interferon-Gamma Production. PLoS One 10(5): e0127262.

    • Niedzielska M, Raffi FA, Tel J, Muench S, Jozefowski K, Alati N, Lahl K, Mages J, Billmeier U, Schiemann M, Appelt UK, Wirtz S, Sparwasser T, Hochrein H, Figdor CG, Keyse SM, Lang R (2015) Selective Expression of the MAPK Phosphatase Dusp9/MKP-4 in Mouse Plasmacytoid Dendritic Cells and Regulation of IFN-beta Production. J Immunol 195(4): 1753-1762.

    • Oumeraci T, Jensen V, Talbot SR, Hofmann W, Kostrzewa M, Schlegelberger B, von Neuhoff N, Haussler S (2015) Comprehensive MALDI-TOF Biotyping of the Non-Redundant Harvard Pseudomonas aeruginosa PA14 Transposon Insertion Mutant Library. PLoS One 10(2): e0117144.

    • Pawar V, Komor U, Kasnitz N, Bielecki P, Pils MC, Gocht B, Moter A, Rohde M, Weiss S, Haussler S (2015) In vivo efficacy of antimicrobials against biofilm producing Pseudomonas aeruginosa. Antimicrob Agents Chemother 59(8): 4974-4981.

    • Pfaender S, Brinkmann J, Todt D, Riebesehl N, Steinmann J, Steinmann J, Pietschmann T, Steinmann E (2015) Mechanisms of viral inactivation methods against hepatitis C virus. Appl Environ Microbiol 81(5): 1616-1621.

    • Pfaender S, Cavalleri JM, Walter S, Doerrbecker J, Campana B, Brown RJ, Burbelo PD, Postel A, Hahn K, Kusuma A, Riebesehl N, Baumgartner W, Becher P, Heim MH, Pietschmann T, Feige K, Steinmann E (2015) Clinical course of infection and viral tissue tropism of hepatitis C virus-like non-primate hepaciviruses in horses. Hepatology 61(2): 448-459.

    • Pfaender S, Walter S, Todt D, Behrendt P, Doerrbecker J, Woelk B, Engelmann M, Gravemann U, Seltsam A, Steinmann J, Burbelo PD, Klawonn F, Feige K, Pietschmann T, Cavalleri JM, Steinmann E (2015) Assessment of cross-species transmission of hepatitis C-related non-primate hepacivirus in a population of humans at high risk of exposure. J Gen Virol 96(9): 2636-2642.

    • Pfefferkorn C, Kallfass C, Lienenklaus S, Spanier J, Kalinke U, Rieder M, Conzelmann KK, Michiels T, Staeheli P (2015) Abortively infected astrocytes appear to represent the main source of interferon-β in the virus-infected brain. J Virol 90(4): 2031-2038.

    • Preusse M, Schughart K, Wilk E, Klawonn F, Pessler F (2015) Hematological parameters in the early phase of influenza A virus infection in differentially susceptible inbred mouse strains. BMC Res Notes 8(n/a): 225.

    • Pustelny C, Komor U, Pawar V, Lorenz A, Bielecka A, Moter A, Gocht B, Eckweiler D, Grothe C, Lunsdorf H, Weiss S, Haussler S (2015) Contribution of Veillonella parvula to Pseudomonas aeruginosa mediated pathogenicity in a murine tumor model system. Infect Immun 83(1): 417-429.

    • Rabenau HF, Schwebke I, Blumel J, Eggers M, Glebe D, Rapp I, Sauerbrei A, Steinmann E, Steinmann J, Willkommen H, Wutzler P (2015) In Process Citation. Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz 58(4-5): 493-504.

    • Rath PM, Schoch B, Adamzik M, Steinmann E, Buer J, Steinmann J (2015) Reply: PCR assay for pathogen detection in ventriculostomy-related meningitis in neurosurgery patients: unanswered questions?. Infection 43(2): 251-252.

    • Salmikangas P, Menezes-Ferreira M, Reischl I, Tsiftsoglou A, Kyselovic J, Borg JJ, Ruiz S, Flory E, Trouvin J, Celis P, Ancans J, Timon M, Pante G, Sladowski D, Lipnik-Stangelj M, Schneider CK (2015) Manufacturing, characterization and control of cell-based medicinal products: challenging paradigms toward commercial use. Regen Med 10(1): 65-78.

    • Schneider CK, Weise M (2015) Regulatorische Aspekte zu Biosimilars: Mythen und Fakten. Z Rheumatol 74(8): 695-700.

    • Schuhmann MK, Kraft P, Stoll G, Lorenz K, Meuth SG, Wiendl H, Nieswandt B, Sparwasser T, Beyersdorf N, Kerkau T, Kleinschnitz C (2015) CD28 superagonist-mediated boost of regulatory T cells increases thrombo-inflammation and ischemic neurodegeneration during the acute phase of experimental stroke. J Cereb Blood Flow Metab 35(1): 6-10.

    • Schulz S, Eckweiler D, Bielecka A, Nicolai T, Franke R, Dotsch A, Hornischer K, Bruchmann S, Duvel J, Haussler S (2015) Elucidation of Sigma Factor-Associated Networks in Pseudomonas aeruginosa Reveals a Modular Architecture with Limited and Function-Specific Crosstalk. PLoS Pathog 11(3): e1004744.

    • Schwebke I, Blumel J, Eggers M, Glebe D, Rapp I, von Rheinbaben F, Sauerbrei A, Steinmann E, Steinmann J, Willkommen H, Wutzler P, Rabenau HF (2015) In Process Citation. Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz 58(4-5): 491-491.

    • Schweitzer A, Akmatov MK, Kindler F, Kemmling Y, Kreienbrock L, Krause G, Pessler F (2015) The impact of distance and duration of travel on participation rates and participants' satisfaction: results from a pilot study at one study centre in Pretest 2 of the German National Cohort. BMJ Open 5(8): e007461.

    • Schweitzer A, Della Beffa C, Akmatov MK, Narchi H, Abaev YK, Sherry DD, Pessler F (2015) Primary Osteomyelitis of the Sternum in the Pediatric Age Group: Report of a New Case and Comprehensive Analysis of Seventy-four Cases. Pediatr Infect Dis J 34(4): e92-e101.

    • Schweitzer A, Krause G, Pessler F, Akmatov MK (2015) Improved coverage and timing of childhood vaccinations in two post-Soviet countries, Armenia and Kyrgyzstan. BMC Public Health 155(1): 798.

    • Skripuletz T, Salinas Tejedor L, Prajeeth CK, Hansmann F, Chhatbar C, Kucman V, Zhang N, Raddatz BB, Detje CN, Suhs KW, Pul R, Gudi V, Kalinke U, Baumgartner W, Stangel M (2015) The antiviral drug ganciclovir does not inhibit microglial proliferation and activation. Sci Rep 5(n/a): 14935.

    • Steinmann J, Becker B, Bischoff B, Steinmann E (2015) Alcohol hand rub or soap and water for removal of norovirus from hands – the debate continues. Journal of Hospital Infection 91(4): 371 - 372.

    • Tarr AW, Khera T, Hueging K, Sheldon J, Steinmann E, Pietschmann T, Brown RJ (2015) Genetic Diversity Underlying the Envelope Glycoproteins of Hepatitis C Virus: Structural and Functional Consequences and the Implications for Vaccine Design. Viruses 7(7): 3995-4046.

    • Tebartz C, Horst SA, Sparwasser T, Huehn J, Beineke A, Peters G, Medina E (2015) A Major Role for Myeloid-Derived Suppressor Cells and a Minor Role for Regulatory T Cells in Immunosuppression during Staphylococcus aureus Infection. J Immunol 194(3): 1100-1111.

    • Torow N, Yu K, Hassani K, Freitag J, Schulz O, Basic M, Brennecke A, Sparwasser T, Wagner N, Bleich A, Lochner M, Weiss S, Forster R, Pabst O, Hornef MW (2015) Active suppression of intestinal CD4TCRalphabeta T-lymphocyte maturation during the postnatal period. Nat Commun 6(n/a): 7725.

    • Unger WW, Mayer CT, Engels S, Hesse C, Perdicchio M, Puttur F, Streng-Ouwehand I, Litjens M, Kalay H, Berod L, Sparwasser T, van Kooyk Y (2015) Antigen targeting to dendritic cells combined with transient regulatory T cell inhibition results in long-term tumor regression. Oncoimmunology 4(8): e970462.

    • Vercammen K, Wei Q, Charlier D, Dotsch A, Haussler S, Schulz S, Salvi F, Gadda G, Spain J, Levin Rybtke M, Tolker-Nielsen T, Dingemans J, Ye L, Cornelis P (2015) Pseudomonas aeruginosa LysR PA4203 regulator NmoR acts as a repressor of the PA4202 nmoA gene encoding a nitronate monooxygenase. J Bacteriol 197(6): 1026-1039.

    • Vogel S, Grabski E, Buschjager D, Klawonn F, Doring M, Wang J, Fletcher E, Bechmann I, Witte T, Durisin M, Schraven B, Mangsbo SM, Schonfeld K, Czeloth N, Kalinke U (2015) Antibody induced CD4 down-modulation of T cells is site-specifically mediated by CD64(+) cells. Sci Rep 5(n/a): 18308.

    • Waffarn EE, Hastey CJ, Dixit N, Choi YS, Cherry S, Kalinke U, Simon SI, Baumgarth N (2015) Infection-induced type I interferons activate CD11b on B-1 cells for subsequent lymph node accumulation. Nature Communications 6(n/a): 8991.

    • Walker A, Skibbe K, Steinmann E, Pfaender S, Kuntzen T, Megger D.A., Groten S, Sitek B, Lauer G.M., Kim A.Y., Pietschmann T, Allen T.M., Timm J. (2015) Distinct escape pathway by HCV genotype 1a from a dominant CD8+ T cell response by selection of altered epitope processing. J Virol doi: 10.1128/JVI.01993-15(n/a).

    • Wang H, El Maadidi S, Fischer J, Grabski E, Dickhofer S, Klimosch S, Flannery SM, Filomena A, Wolz OO, Schneiderhan-Marra N, Loffler MW, Wiese M, Pichulik T, Mullhaupt B, Semela D, Dufour JF, East German, Swiss Hepatitis C.VirusStudyGroups, Bochud PY, Bowie AG, Kalinke U, Berg T, Weber AN (2015) A frequent hypofunctional IRAK2 variant is associated with reduced spontaneous hepatitis C virus clearance. Hepatol 62(5): 1375-1387.

    • Wenzel UA, Fernandez-Santoscoy M, Tam MA, Tegtmeyer P, Wick MJ (2015) Synergy between CD40 and MyD88 Does Not Influence Host Survival to Salmonella Infection. Front Immunol 6(n/a): 460.

    • Yang BH, Floess S, Hagemann S, Deyneko IV, Groebe L, Pezoldt J, Sparwasser T, Lochner M, Huehn J (2015) Development of a unique epigenetic signature during in vivo Th17 differentiation. Nucleic Acids Res 43(3): 1537-1548.

    • Yodoi K, Yamashita T, Sasaki N, Kasahara K, Emoto T, Matsumoto T, Kita T, Sasaki Y, Mizoguchi T, Sparwasser T, Hirata KI (2015) Foxp3+ Regulatory T Cells Play a Protective Role in Angiotensin II-Induced Aortic Aneurysm Formation in Mice. Hypertension 65(4): 889-895.

    2014

    • Abou-El-Enein M, Bauer G, Reinke P, Renner M, Schneider CK (2014) A roadmap toward clinical translation of genetically-modified stem cells for treatment of HIV. Trends Mol Med d20(11): 632-642.

    • Akmatov MK, Mehraj J, Gatzemeier A, Strompl J, Witte W, Krause G, Pessler F (2014) Serial home-based self-collection of anterior nasal swabs to detect Staphylococcus aureus carriage in a randomized population-based study in Germany. Int J Infect Dis 25(n/a): 4-10.

    • Anggakusuma A, Colpitts CC, Schang LM, Rachmawati H, Frentzen A, Pfaender S, Behrendt P, Brown RJ, Bankwitz D, Steinmann J, Ott M, Meuleman P, Rice CM, Ploss A, Pietschmann T, Steinmann E (2014) Turmeric curcumin inhibits entry of all hepatitis C virus genotypes into human liver cells. Gut 63(7): 1137-1149.

    • Anggakusuma, Colpitts CC, Schang LM, Rachmawati H, Frentzen A, Pfaender S, Behrendt P, Brown RJ, Bankwitz D, Steinmann J, Ott M, Meuleman P, Rice CM, Ploss A, Pietschmann T, Steinmann E (2014) Turmeric curcumin inhibits entry of all hepatitis C virus genotypes into human liver cells. Gut 63(7): 1137-1149.

    • Arnold P, Himmels P, Weiss S, Decker TM, Markl J, Gatterdam V, Tampe R, Bartholomaeus P, Dietrich U, Durr R (2014) Antigenic and 3D structural characterization of soluble X4 and hybrid X4-R5 HIV-1 Env trimers. Retrovirology 11(n/a): 42.

    • Arnold-Schrauf C, Dudek M, Dielmann A, Pace L, Swallow M, Kruse F, Kuhl AA, Holzmann B, Berod L, Sparwasser T (2014) Dendritic Cells Coordinate Innate Immunity via MyD88 Signaling to Control Listeria monocytogenes Infection. Cell Rep 6(4): 698-708.

    • Bald T, Landsberg J, Lopez-Ramos D, Renn M, Glodde N, Jansen P, Gaffal E, Steitz J, Tolba R, Kalinke U, Limmer A, Jonsson G, Holzel M, Tuting T (2014) Immune-cell poor melanomas benefit from PD-1 blockade after targeted type I IFN activation. Cancer Discov 4(6): 674-687.

    • Bankwitz D, Vieyres G, Hueging K, Bitzegeio J, Doepke M, Chhatwal P, Haid S, Catanese MT, Zeisel MB, Nicosia A, Baumert TF, Kaderali L, Pietschmann T (2014) Role of the hypervariable region 1 (HVR1) for the interplay of hepatitis C virus with entry factors and lipoproteins. J Virol 88(21): 12644-12655.

    • Barbier M, Damron FH, Bielecki P, Suarez-Diez M, Puchalka J, Alberti S, Dos Santos VM, Goldberg JB (2014) From the Environment to the Host: Re-Wiring of the Transcriptome of Pseudomonas aeruginosa from 22 degrees C to 37 degrees C. PLoS One 9(2): e89941.

    • Bartholomaeus P, Semmler LY, Bukur T, Boisguerin V, Romer PS, Tabares P, Chuvpilo S, Tyrsin DY, Matskevich A, Hengel H, Castle J, Hunig T, Kalinke U (2014) Cell Contact-Dependent Priming and Fc Interaction with CD32+ Immune Cells Contribute to the TGN1412-Triggered Cytokine Response. J Immunol 192(5): 2091-2098.

    • Behrendt P, Steinmann E, Manns MP, Wedemeyer H (2014) The impact of hepatitis E in the liver transplant setting. Journal of hepatology 61(6): 1418-1429.

    • Berneman-Zeitouni D, Molakandov K, Elgart M, Mor E, Fornoni A, Dominguez MR, Kerr-Conte J, Ott M, Meivar-Levy I, Ferber S (2014) The temporal and hierarchical control of transcription factors-induced liver to pancreas transdifferentiation. PLoS One 9(2): 387812.

    • Berod L, Friedrich C, Nandan A, Freitag J, Hagemann S, Harmrolfs K, Sandouk A, Hesse C, Castro CN, Bahre H, Tschirner SK, Gorinski N, Gohmert M, Mayer CT, Huehn J, Ponimaskin E, Abraham WR, Muller R, Lochner M, Sparwasser T (2014) De novo fatty acid synthesis controls the fate between regulatory T and T helper 17 cells. Nat Med 20(11): 1327-1333.

    • Berod L, Stuve P, Swallow M, Arnold-Schrauf C, Kruse F, Gentilini MV, Freitag J, Holzmann B, Sparwasser T (2014) MyD88 signalling in myeloid cells is sufficient to prevent chronic mycobacterial infection. Eur J Immunol 44(5): 1399-1409.

    • Berod L, Stuve P, Varela F, Behrends J, Swallow M, Kruse F, Krull F, Ghorbani P, Mayer CT, Holscher C, Sparwasser T (2014) Rapid Rebound of the Treg Compartment in DEREG Mice Limits the Impact of Treg Depletion on Mycobacterial Burden, but Prevents Autoimmunity. PLoS One 9(7): e102804.

    • Bielecki P, Muthukumarasamy U, Eckweiler D, Bielecka A, Pohl S, Schanz A, Niemeyer U, Oumeraci T, von Neuhoff N, Ghigo JM, Haussler S (2014) In vivo mRNA profiling of uropathogenic Escherichia coli from diverse phylogroups reveals common and group-specific gene expression profiles. MBio 5(4): e01075-14.

    • Blanka A, Schulz S, Eckweiler D, Franke R, Bielecka A, Nicolai T, Casilag F, Duvel J, Abraham WR, Kaever V, Haussler S (2014) Identification of the alternative sigma factor SigX regulon and its implications for Pseudomonas aeruginosa pathogenicity. J Bacteriol 196(2): 345-356.

    • Blankenhaus B, Reitz M, Brenz Y, Eschbach ML, Hartmann W, Haben I, Sparwasser T, Huehn J, Kuhl A, Feyerabend TB, Rodewald HR, Breloer M (2014) Foxp3(+) Regulatory T Cells Delay Expulsion of Intestinal Nematodes by Suppression of IL-9-Driven Mast Cell Activation in BALB/c but Not in C57BL/6 Mice. PLoS Pathog 10(2): e1003913.

    • Borg JJ, Serracino-Inglott A, Azzopardi LM, Schneider CK (2014) Comment On: "EU's New Pharmacovigilance Legislation: Considerations for Biosimilars". Drug Saf 37(2): 123-124.

    • Borrero-de Acuna JM, Bielecka A, Haussler S, Schobert M, Jahn M, Wittmann C, Jahn D, Poblete-Castro I (2014) Production of medium chain length polyhydroxyalkanoate in metabolic flux optimized Pseudomonas putida. Microb Cell Fact 13(1): 88.

    • Brouwer S, Pustelny C, Ritter C, Klinkert B, Narberhaus F, Haussler S (2014) The PqsR and RhlR transcriptional regulators determine the level of PQS synthesis in Pseudomonas aeruginosa by producing two different pqsABCDE mRNA isoforms. J Bacteriol 196(23): 4163-4171.

    • Brown RJ, Koutsoudakis G, Urbanowicz RA, Mirza D, Ginkel C, Riebesehl N, Calland N, Albecka A, Price L, Hudson N, Descamps V, Backx M, McClure CP, Duverlie G, Pecheur EI, Dubuisson J, Perez-Del-Pulgar S, Forns X, Steinmann E, Tarr AW, Pietschmann T, Ball JK (2014) Analysis of serine codon conservation reveals diverse phenotypic constraints on Hepatitis C Virus glycoprotein evolution. J Virol 88(1): 667-678.

    • Cabot G, Bruchmann S, Mulet X, Zamorano L, Moya B, Juan C, Haussler S, Oliver A (2014) Pseudomonas aeruginosa Ceftolozane-Tazobactam Resistance Development Requires Multiple Mutations Leading to Overexpression and Structural Modification of AmpC. Antimicrob Agents Chemother 58(6): 3091-3099.

    • Castell S, Akmatov MK, Obi N, Flesh-Janys D, Nieters A, Kemmling Y, Pessler F, Krause G (2014) Test-retest reliability of an infectious disease questionnaire and evaluation of self-assessed vulnerability to infections : Findings of Pretest 2 of the German National Cohort. Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz 57(11): 1300-1307.

    • Chrobak P, Afkhami S, Priceputu E, Poudrier J, Meunier C, Hanna Z, Sparwasser T, Jolicoeur P (2014) HIV Nef Expression Favors the Relative Preservation of CD4+ T Regulatory Cells That Retain Some Important Suppressive Functions. J Immunol 192(4): 1681-1692.

    • Conrad E, Resch TK, Gogesch P, Kalinke U, Bechmann I, Bogdan C, Waibler Z (2014) Protection against RNA-induced liver damage by myeloid cells requires type I interferon and IL-1 receptor antagonist in mice. Hepatology 59(4): 1555-1563.

    • Crouse J, Bedenikovic G, Wiesel M, Ibberson M, Xenarios I, Von Laer D, Kalinke U, Vivier E, Jonjic S, Oxenius A (2014) Type I Interferons Protect T Cells against NK Cell Attack Mediated by the Activating Receptor NCR1. Immunity 40(6): 961-973.

    • Deest M, Westhaus S, Steinmann E, Manns MP, von Hahn T, Ciesek S (2014) Impact of single nucleotide polymorphisms in the essential HCV entry factor CD81 on HCV infectivity and neutralization. Antiviral Res 101(n/a): 37-44.

    • Doerrbecker J, Friesland M, Riebesehl N, Ginkel C, Behrendt P, Brown RJ, Ciesek S, Wedemeyer H, Sarrazin C, Kaderali L, Pietschmann T, Steinmann E (2014) Incorporation of primary patient-derived glycoproteins into authentic infectious hepatitis C virus particles. Hepatology 60(2): 508-520.

    • Doring M, Lessin I, Frenz T, Spanier J, Kessler A, Tegtmeyer P, Dag F, Thiel N, Trilling M, Lienenklaus S, Weiss S, Scheu S, Messerle M, Cicin-Sain L, Hengel H, Kalinke U (2014) M27 expressed by cytomegalovirus counteracts effective type I IFN induction of myeloid cells, but not of plasmacytoid dendritic cells. J Virol 88(23): 13638-13650.

    • Eckweiler D, Bunk B, Sproer C, Overmann J, Haussler S (2014) Complete Genome Sequence of Highly Adherent Pseudomonas aeruginosa Small-Colony Variant SCV20265. Genome Announc 2(1).

    • Ehrlich A, Moreno Castilho T, Goldsmith-Pestana K, Chae WJ, Bothwell AL, Sparwasser T, McMahon-Pratt D (2014) The Immunotherapeutic Role of Regulatory T Cells in Leishmania (Viannia) panamensis Infection. J Immunol 193(6): 2961-2970.

    • Espinoza Mora Mdel R, Steeg C, Tartz S, Heussler V, Sparwasser T, Link A, Fleischer B, Jacobs T (2014) Depletion of Regulatory T Cells Augments a Vaccine-Induced T Effector Cell Response against the Liver-Stage of Malaria but Fails to Increase Memory. PLoS One 9(8): e104627.

    • Fleige H, Ravens S, Moschovakis GL, Bolter J, Willenzon S, Sutter G, Haussler S, Kalinke U, Prinz I, Forster R (2014) IL-17-induced CXCL12 recruits B cells and induces follicle formation in BALT in the absence of differentiated FDCs. J Exp Med 211(4): 643-651.

    • Fleige H, Ravens S, Moschovakis GL, Bolter J, Willenzon S, Sutter G, Haussler S, Kalinke U, Prinz I, Forster R (2014) IL-17-induced CXCL12 recruits B cells and induces follicle formation in BALT in the absence of differentiated FDCs. J Exp Med 211(4): 643-651.

    • Frentzen A, Anggakusuma, Guerlevik E, Hueging K, Knocke S, Ginkel C, Brown RJ, Heim M, Dill MT, Kroger A, Kalinke U, Kaderali L, Kuehnel F, Pietschmann T (2014) Cell entry, efficient RNA replication, and production of infectious hepatitis C virus progeny in mouse liver-derived cells. Hepatology 59(1): 78-88.

    • Frentzen A, Kusuma A, Guerlevik E, Hueging K, Knocke S, Ginkel C, Brown RJ, Heim M, Dill MT, Kroger A, Kalinke U, Kaderali L, Kuehnel F, Pietschmann T (2014) Cell entry, efficient RNA replication, and production of infectious hepatitis C virus progeny in mouse liver-derived cells. Hepatology 59(1): 78-88.

    • Frenz T, Graalmann L, Detje CN, Doring M, Grabski E, Scheu S, Kalinke U (2014) Independent of Plasmacytoid Dendritic Cell (pDC) infection, pDC Triggered by Virus-Infected Cells Mount Enhanced Type I IFN Responses of Different Composition as Opposed to pDC Stimulated with Free Virus. J Immunol 193(5): 2496-2503.

    • Gabaev I, Elbasani E, Ameres S, Steinbruck L, Stanton R, Doring M, Lenac Rovis T, Kalinke U, Jonjic S, Moosmann A, Messerle M (2014) Expression of the Human Cytomegalovirus UL11 Glycoprotein in Viral Infection and Evaluation of its Effect on Virus-Specific CD8 T Cells. J Virol 88(24): 14326-14339.

    • Ganesh V, Baru AM, Hesse C, Friedrich C, Glage S, Gohmert M, Janke C, Sparwasser T (2014) Salmonella Typhimurium Infection Induced CD11b+Gr1+ Cells Ameliorate Allergic Airway Inflammation. Infect Immun 82(3): 1052-1063.

    • Gerold G, Pietschmann T (2014) A circuit of paracrine signals between liver sinusoid endothelial cells and hepatocytes regulates hepatitis C virus replication. Hepatology 59(2): 363-365.

    • Gerold G, Pietschmann T (2014) The HCV Life Cycle: In vitro Tissue Culture Systems and Therapeutic Targets. Dig Dis 32(5): 525-537.

    • Haid S, Grethe C, Dill MT, Heim M, Kaderali L, Pietschmann T (2014) Isolate-dependent use of Claudins for cell entry by hepatitis C virus. Hepatology 59(1): 24-34.

    • Haque A, Best SE, Montes de Oca M, James KR, Ammerdorffer A, Edwards CL, de Labastida Rivera F, Amante FH, Bunn PT, Sheel M, Sebina I, Koyama M, Varelias A, Hertzog PJ, Kalinke U, Gun SY, Renia L, Ruedl C, Macdonald KP, Hill GR, Engwerda CR (2014) Type I IFN signaling in CD8- DCs impairs Th1-dependent malaria immunity. J Clin Invest 124(6): 2483-2496.

    • Hueging K, Doepke M, Vieyres G, Bankwitz D, Frentzen A, Doerrbecker J, Gumz F, Haid S, Wolk B, Kaderali L, Pietschmann T (2014) Apolipoprotein E co-determines tissue-tropism of hepatitis C virus and it is crucial for viral cell-to-cell transmission by contributing to a post-envelopment step of assembly. J Virol 88(3): 1433-1446.

    • Irving WL, Rupp D, McClure CP, Than LM, Titman A, Ball JK, Steinmann E, Bartenschlager R, Pietschmann T, Brown RJ (2014) Development of a high-throughput pyrosequencing assay for monitoring temporal evolution and resistance associated variant emergence in the Hepatitis C virus protease coding-region. Antiviral Res 110c(n/a): 52-59.

    • Jost NH, Abel S, Hutzler M, Sparwasser T, Zimmermann A, Roers A, Muller W, Klopfleisch R, Hengel H, Westendorf AM, Buer J, Hansen W (2014) Regulatory T cells and T-cell-derived IL-10 interfere with effective anti-cytomegalovirus immune response. Immunol Cell Biol 92(10): 860-871.

    • Kuhn A, Nieters A, Kottgen A, Goek ON, Michels K, Nothlings U, Jacobs G, Meisinger C, Pessler F, Akmatov MF, Kuhnisch J, Moebus S, Glocker E, Naus S, Keimling M, Leitzmann M, Linseisen J, Sarioglu H, von Toerne C, Hauck SM, Wallaschofski H, Wichmann HE, Illig T (2014) Feasibility and quality development of biomaterials in the pretest studies of the German National Cohort. Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz 57(11): 1255-1263.

    • Lange M, Fiedler M, Bankwitz D, Osburn W, Viazov S, Brovko O, Zekri AR, Khudyakov Y, Nassal M, Pumpens P, Pietschmann T, Timm J, Roggendorf M, Walker A (2014) Hepatitis C virus hypervariable region 1 variants presented on hepatitis B virus capsid-like particles induce cross-neutralizing antibodies. PLoS One 9(7): e102235.

    • Lebel ME, Daudelin JF, Chartrand K, Tarrab E, Kalinke U, Savard P, Labrecque N, Leclerc D, Lamarre A (2014) Nanoparticle Adjuvant Sensing by TLR7 Enhances CD8+ T Cell-Mediated Protection from Listeria Monocytogenes Infection. J Immunol 192(3): 1071-1078.

    • Liehl P, Zuzarte-Luis V, Chan J, Zillinger T, Baptista F, Carapau D, Konert M, Hanson KK, Carret C, Lassnig C, Muller M, Kalinke U, Saeed M, Chora AF, Golenbock DT, Strobl B, Prudencio M, Coelho LP, Kappe SH, Superti-Furga G, Pichlmair A, Vigario AM, Rice CM, Fitzgerald KA, Barchet W, Mota MM (2014) Host-cell sensors for Plasmodium activate innate immunity against liver-stage infection. Nat Med 20(1): 47-53.

    • Lindenberg M, Solmaz G, Puttur F, Sparwasser T (2014) Mouse cytomegalovirus infection overrules T regulatory cell suppression on natural killer cells. J Virol 11(n/a): 145.

    • Mall S, Akmatov MK, Schultze A, Ahrens W, Obi N, Pessler F, Krause G (2014) Web-based questionnaires to capture acute infections in long-term cohorts : Findings of a feasibility study. Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz 57(11): 1308-1314.

    • Mayer CT, Ghorbani P, Kuhl AA, Stuve P, Hegemann M, Berod L, Gershwin ME, Sparwasser T (2014) Few Foxp3 regulatory T cells are sufficient to protect adult mice from lethal autoimmunity. Euro J Immunol 44(10): 2990-3002.

    • Mayer CT, Ghorbani P, Nandan A, Dudek M, Arnold-Schrauf C, Hesse C, Berod L, Stuve P, Puttur F, Merad M, Sparwasser T (2014) Selective and efficient generation of functional Batf3-dependent CD103+ dendritic cells from mouse bone marrow. Blood 124(20): 3081-3091.

    • Mayer CT, Lahl K, Milanez-Almeida P, Watts D, Dittmer U, Fyhrquist N, Huehn J, Kopf M, Kretschmer K, Rouse B, Sparwasser T (2014) Advantages of Foxp3(+) regulatory T cell depletion using DEREG mice. Immun Inflamm Dis 2(3): 162-165.

    • Mayer CT, Sparwasser T (2014) Assessing the suppressive activity of foxp3(+) regulatory T cells. Methods Mol Biol 1193(n/a): 85-96.

    • Mayer CT, Tian L, Hesse C, Kuhl AA, Swallow M, Kruse F, Thiele M, Gershwin ME, Liston A, Sparwasser T (2014) Anti-CD4 treatment inhibits autoimmunity in scurfy mice through the attenuation of co-stimulatory signals. J Autoimmun 50(n/a): 23-32.

    • Mehraj J, Akmatov MK, Strompl J, Gatzemeier A, Layer F, Werner G, Pieper DH, Medina E, Witte W, Pessler F, Krause G (2014) Methicillin-Sensitive and Methicillin-Resistant Staphylococcus aureus Nasal Carriage in a Random Sample of Non-Hospitalized Adult Population in Northern Germany. PLoS One 9(9): e107937.

    • Meyer Zu Horste G, Cordes S, Mausberg AK, Zozulya AL, Wessig C, Sparwasser T, Mathys C, Wiendl H, Hartung HP, Kieseier BC (2014) FoxP3+ Regulatory T Cells Determine Disease Severity in Rodent Models of Inflammatory Neuropathies. PLoS One 9(10): e108756.

    • Nair S, Michaelsen-Preusse K, Finsterbusch K, Stegemann-Koniszewski S, Bruder D, Grashoff M, Korte M, Koster M, Kalinke U, Hauser H, Kroger A (2014) Interferon regulatory factor-1 protects from fatal neurotropic infection with vesicular stomatitis virus by specific inhibition of viral replication in neurons. PLoS Pathog 10(3): e1003999.

    • Narayanan G, Cossu G, Galli MC, Flory E, Ovelgonne H, Salmikangas P, Schneider CK, Trouvin JH (2014) Clinical development of gene therapy needs a tailored approach: a regulatory perspective from the European union. Hum Gene Ther Clin Dev 25(1): 1-6.

    • Novoselova N, Beffa CD, Wang J, Li J, Pessler F, Klawonn F (2014) HUM Calculator and HUM package for R: easy-to-use software tools for multicategory receiver operating characteristic analysis. Bioinformatics 30(11): 1635-1636.

    • Pastille E, Bardini K, Fleissner D, Adamczyk A, Frede A, Wadwa M, von Smolinski D, Kasper S, Sparwasser T, Gruber AD, Schuler M, Sackaguchi S, Roers A, Muller W, Hansen W, Buer J, Westendorf AM (2014) Transient ablation of regulatory T cells improves antitumor immunity in colitis-associated colon cancer. Cancer Res 74(16): 4258-4269.

    • Pawar V, Crull K, Komor U, Kasnitz N, Frahm M, Kocijancic D, Westphal K, Leschner S, Wolf K, Loessner H, Rohde M, Haussler S, Weiss S (2014) Murine solid tumours as a novel model to study bacterial biofilm formation in vivo. J Intern Med 276(2): 130-139.

    • Perez F, Hujer AM, Marshall SH, Ray AJ, Rather PN, Suwantarat N, Dumford, D 3rd, O'Shea P, Domitrovic TN, Salata RA, Chavda KD, Chen L, Kreiswirth BN, Vila AJ, Haussler S, Jacobs MR, Bonomo RA (2014) Extensively Drug Resistant (XDR) Pseudomonas aeruginosa Containing blaVIM-2 and Elements of Salmonella Genomic Island 2: A New Genetic Resistance Determinant in Northeast Ohio. Antimicrob Agents Chemother 58(10): 5929-5935.

    • Pessler F, Ogdie AR, Mayer CT, Kretzschmar WW, Dai L, Elsaman AM, Einhorn E, Krenn V, Schumacher HR (2014) Amyloid arthropathy associated with multiple myeloma: polyarthritis without synovial infiltration of CD20+ or CD38+ cells. Amyloid 21(1): 28-34.

    • Pessler F, Ogdie AR, Mayer CT, Kretzschmar WW, Dai L, Elsaman AM, Einhorn E, Krenn V, Schumacher HR (2014) Amyloid arthropathy associated with multiple myeloma: polyarthritis without synovial infiltration of CD20+ or CD38+ cells. Amyloid 21(1): 28-34.

    • Petzold C, Steinbronn N, Gereke M, Strasser RH, Sparwasser T, Bruder D, Geffers R, Schallenberg S, Kretschmer K (2014) Fluorochrome-based definition of naturally occurring Foxp3 regulatory T cells of intra- and extrathymic origin. Euro J Immunol 44(12): 3632-3645.

    • Pietschmann T (2014) In sero veritas: what serum markers teach us about HCV infection of primary human hepatocytes. Gut 63(9): 1375-1377.

    • Pohl S, Klockgether J, Eckweiler D, Khaledi A, Schniederjans M, Chouvarine P, Tummler B, Haussler S (2014) The extensive set of accessory Pseudomonas aeruginosa genomic components. FEMS Microbiol Lett 356(2): 235-241.

    • Rath PM, Schoch B, Adamzik M, Steinmann E, Buer J, Steinmann J (2014) Value of multiplex PCR using cerebrospinal fluid for the diagnosis of ventriculostomy-related meningitis in neurosurgery patients. Infection 42(2): 621-627.

    • Schmidt A, Belaaouaj A, Bissinger R, Koller G, Malleret L, D'Orazio C, Facchinelli M, Schulte-Hubbert B, Molinaro A, Holst O, Hammermann J, Schniederjans M, Meyer KC, Damkiaer S, Piacentini G, Assael B, Bruce K, Haussler S, Lipuma JJ, Seelig J, Worlitzsch D, Doring G (2014) Neutrophil elastase-mediated increase in airway temperature during inflammation. J Cyst Fibros 58(10): 5929-5935.

    • Schultze A, Akmatov MK, Andrzejak M, Karras N, Kemmling Y, Maulhardt A, Wieghold S, Ahrens W, Gunther K, Schlenz H, Krause G, Pessler F (2014) Comparison of stool collection on site versus at home in a population-based study : Feasibility and participants' preference in Pretest 2 of the German National Cohort. Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz 57(11): 1264-1269.

    • Schultze A, Akmatov MK, Castell S, Karch A, Ahrens W, Gunther K, Schlenz H, Flesch-Janys D, Obi N, Pessler F, Krause G (2014) Collection of vaccination data in the German National Cohort : Findings of a feasibility study in three study centers. Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz 57(11): 1292-1299.

    • Schulz S, Haussler S (2014) Chromatin Immunoprecipitation for ChIP-chip and ChIP-seq. Methods Mol Biol 1149:(n/a): 591-605.

    • Schulze B, Piehler D, Eschke M, von Buttlar H, Kohler G, Sparwasser T, Alber G (2014) CD4 FoxP3 regulatory T cells suppress fatal T helper 2 cell immunity during pulmonary fungal infection. European Journal of Immnuology 44(12): 3596-3604.

    • Shankar G, Arkin S, Cocea L, Devanarayan V, Kirshner S, Kromminga A, Quarmby V, Richards S, Schneider CK, Subramanyam M, Swanson S, Verthelyi D, Yim S (2014) Assessment and Reporting of the Clinical Immunogenicity of Therapeutic Proteins and Peptides-Harmonized Terminology and Tactical Recommendations. Aaps J 16(4): 658-673.

    • Sievers C, Akmatov MK, Kreienbrock L, Hille K, Ahrens W, Gunther K, Flesch-Janys D, Obi N, Michels KB, Fricke J, Greiser KH, Kaaks R, Peter HH, Pessler F, Nieters A, Krause G (2014) Evaluation of a questionnaire to assess selected infectious diseases and their risk factors : Findings of a multicenter study. Evaluation of a questionnaire to assess selected infectious diseases and their risk factors : Findings of a multicenter study 57(11): 1283-1291.

    • Spanier J, Lienenklaus S, Paijo J, Kessler A, Borst K, Heindorf S, Baker DP, Kroger A, Weiss S, Detje CN, Staeheli P, Kalinke U (2014) Concomitant TLR/RLH Signaling of Radioresistant and Radiosensitive Cells Is Essential for Protection against Vesicular Stomatitis Virus Infection. J Immunol 193(6): 3045-3054.

    • Svitek N, Gerhauser I, Goncalves C, Grabski E, Doring M, Kalinke U, Anderson DE, Cattaneo R, von Messling V (2014) Morbillivirus Control of the Interferon Response: Relevance of STAT2 and mda5 but not STAT1 for Canine Distemper Virus Virulence in Ferrets. J Virol 88(5): 2941-2950.

    • Vercauteren K, Van Den Eede N, Mesalam AA, Belouzard S, Catanese MT, Bankwitz D, Wong-Staal F, Cortese R, Dubuisson J, Rice CM, Pietschmann T, Leroux-Roels G, Nicosia A, Meuleman P (2014) Successful anti-SR-BI mAb therapy in humanized mice after challenge with HCV variants with in vitro resistance to SR-BI-targeting agents. Hepatology 9(7): e102235.

    • Vidigal PG, Dittmer S, Steinmann E, Buer J, Rath PM, Steinmann J (2014) Adaptation of Stenotrophomonas maltophilia in cystic fibrosis: Molecular diversity, mutation frequency and antibiotic resistance. Int J Med Microbiol 304(5-6): 613-619.

    • Vidigal PG, Musken M, Becker KA, Haussler S, Wingender J, Steinmann E, Kehrmann J, Gulbins E, Buer J, Rath PM, Steinmann J (2014) Effects of Green Tea Compound Epigallocatechin-3-Gallate against Stenotrophomonas maltophilia Infection and Biofilm. PLoS One 9(4): e92876.

    • Vidigal PG, Musken M, Becker KA, Haussler S, Wingender J, Steinmann E, Kehrmann J, Gulbins E, Buer J, Rath PM, Steinmann J (2014) Effects of Green Tea Compound Epigallocatechin-3-Gallate against Stenotrophomonas maltophilia Infection and Biofilm. PLoS One 9(4): e92876.

    • Vieyres G, Dubuisson J, Pietschmann T (2014) Incorporation of hepatitis C virus e1 and e2 glycoproteins: the keystones on a peculiar virion. Viruses 6(3): 1149-1187.

    • Villalta SA, Rosenthal W, Martinez L, Kaur A, Sparwasser T, Tidball JG, Margeta M, Spencer MJ, Bluestone JA (2014) Regulatory T cells suppress muscle inflammation and injury in muscular dystrophy. Sci Transl Med 6(258): 258ra142.

    • Volz A, Langenmayer M, Jany S, Kalinke U, Sutter G (2014) Rapid expansion of CD8+ T cells in wildtype and type I interferon receptor deficient mice correlates with protection after low-dose emergency immunization with Modified Vaccinia virus Ankara. J Virol 88(18): 10946-10957.

    • Wang Y, Sparwasser T, Figlin R, Kim HL (2014) Foxp3+ T cells inhibit antitumor immune memory modulated by mTOR inhibition. Cancer Res 74(8): 2217-2228.

    • Wang Z, Friedrich C, Hagemann SC, Korte WH, Goharani N, Cording S, Eberl G, Sparwasser T, Lochner M (2014) Regulatory T cells promote a protective Th17-associated immune response to intestinal bacterial infection with C. rodentium. Mucosal Immunol 7(6): 1290-1301.

    • Weber E, Finsterbusch K, Lindquist R, Nair S, Lienenklaus S, Gekara NO, Janik D, Weiss S, Kalinke U, Overby AK, Kroger A (2014) Type I interferon protects mice from fatal neurotropic infection with Langat virus by systemic and local anti-viral response. J Virol 88(21): 12202-12212.

    • Weise M, Kurki P, Wolff-Holz E, Bielsky MC, Schneider CK (2014) Biosimilars: the science of extrapolation. Blood 124(22): 3191-3196.

    • Zheng LS, Hitoshi S, Kaneko N, Takao K, Miyakawa T, Tanaka Y, Xia H, Kalinke U, Kudo K, Kanba S, Ikenaka K, Sawamoto K (2014) Mechanisms for Interferon-alpha-Induced Depression and Neural Stem Cell Dysfunction. Stem cell reports 3(1): 73-84.

    • Zust R, Toh YX, Valdes I, Cerny D, Heinrich J, Hermida L, Marcos E, Guillen G, Kalinke U, Shi PY, Fink K (2014) Type I IFN signals in macrophages and dendritic cells control dengue virus infection: implications for a new mouse model to test dengue vaccines. J Virol 88(13): 7276-7285.

    • van Aerts LA, De Smet K, Reichmann G, Willem van der Laan J, Schneider CK (2014) Biosimilars entering the clinic without animal studies: A paradigm shift in the European Union. mAbs 6(5).

    2013

    • Abel T, El Filali E, Waern J, Schneider IC, Yuan Q, Munch RC, Hick M, Warnecke G, Madrahimov N, Kontermann RE, Schuttrumpf J, Muller UC, Seppen J, Ott M, Buchholz CJ (2013) Specific gene delivery to liver sinusoidal and artery endothelial cells. Blood 122(12): 2030-2038.

    • Ahmad I, Wigren E, Le Guyon S, Vekkeli S, Blanka A, El Mouali Y, Anwar N, Chuah ML, Lunsdorf H, Frank R, Rhen M, Liang ZX, Lindqvist Y, Romling U (2013) The EAL-like protein STM1697 regulates virulence phenotypes, motility and biofilm formation in Salmonella typhimurium. Mol Microbiol 90(6): 1216-1232.

    • Aiuti A, Cossu G, de Felipe P, Galli MC, Narayanan G, Renner M, Stahlbom A, Schneider CK, Voltz-Girolt C (2013) The Committee for Advanced Therapies' (CAT) reflection paper on management of clinical risks deriving from insertional mutagenesis. Hum Gene Ther Clin Dev 24(2): 47-54.

    • Akhmetzyanova I, Zelinskyy G, Schimmer S, Brandau S, Altenhoff P, Sparwasser T, Dittmer U (2013) Tumor-specific CD4(+) T cells develop cytotoxic activity and eliminate virus-induced tumor cells in the absence of regulatory T cells. Cancer Immunol Immunother 62(2): 257-271.

    • Barkholt L, Flory E, Jekerle V, Lucas-Samuel S, Ahnert P, Bisset L, Buscher D, Fibbe W, Foussat A, Kwa M, Lantz O, Maciulaitis R, Palomaki T, Schneider CK, Sensebe L, Tachdjian G, Tarte K, Tosca L, Salmikangas P (2013) Risk of tumorigenicity in mesenchymal stromal cell-based therapies-Bridging scientific observations and regulatory viewpoints. Cytotherapy 15(7): 753-759.

    • Beffa CD, Slansky E, Pommerenke C, Klawonn F, Li J, Dai L, Schumacher Jr HR, Pessler F (2013) The relative composition of the inflammatory infiltrate as an additional tool for synovial tissue classification. PLoS One 8(8): e72494.

    • Behrendt P, Doerrbecker J, Riebesehl N, Wilhelm C, Ciesek S, Erichsen TJ, Steinmann J, Ott M, Manns MP, Pietschmann T, Steinmann E (2013) Stability and transmission of hepatitis C virus in different anesthetic agents. Am J Infect Control 41(10): 942-943.

    • Behrendt P, Doerrbecker J, Riebesehl N, Wilhelm C, Ciesek S, Erichsen TJ, Steinmann J, Ott M, Manns MP, Pietschmann T, Steinmann E (2013) Stability and transmission of hepatitis C virus in different anesthetic agents. Am J Infect Control 41(10): 942-943.

    • Bielecki P, Komor U, Bielecka A, Musken M, Puchalka J, Pletz MW, Ballmann M, Martins Dos Santos VA, Weiss S, Haussler S (2013) Ex vivo transcriptional profiling reveals a common set of genes important for the adaptation of Pseudomonas aeruginosa to chronically infected host sites. Environ Microbiol 15(2): 570-587.

    • Bobadilla Fazzini RA, Skindersoe ME, Bielecki P, Puchalka J, Givskov M, Martins Dos Santos VA (2013) Protoanemonin: a natural quorum sensing inhibitor that selectively activates iron starvation response. Environ Microbiol 15(1): 111-120.

    • Britten CM, Singh-Jasuja H, Flamion B, Hoos A, Huber C, Kallen KJ, Khleif SN, Kreiter S, Nielsen M, Rammensee HG, Sahin U, Hinz T, Kalinke U (2013) The regulatory landscape for actively personalized cancer immunotherapies. Nat Biotechnol 31(10): 880-882.

    • Bruchmann S, Dotsch A, Nouri B, Chaberny IF, Haussler S (2013) Quantitative contribution of target alteration and decreased drug accumulation to Pseudomonas aeruginosa fluoroquinolone resistance. Antimicrob Agents Chemother 57(3): 1361-1368.

    • Bunse CE, Borchers S, Varanasi PR, Tischer S, Figueiredo C, Immenschuh S, Kalinke U, Kohl U, Goudeva L, Maecker-Kolhoff B, Ganser A, Blasczyk R, Weissinger EM, Eiz-Vesper B (2013) Impaired Functionality of Antiviral T Cells in G-CSF Mobilized Stem Cell Donors: Implications for the Selection of CTL Donor. PLoS One 8(12): e77925.

    • Chai Q, Onder L, Scandella E, Gil-Cruz C, Perez-Shibayama C, Cupovic J, Danuser R, Sparwasser T, Luther SA, Thiel V, Rulicke T, Stein JV, Hehlgans T, Ludewig B (2013) Maturation of Lymph Node Fibroblastic Reticular Cells from Myofibroblastic Precursors Is Critical for Antiviral Immunity. Immunity 38(5): 1013-1024.

    • Doerrbecker J, Behrendt P, Mateu-Gelabert P, Ciesek S, Riebesehl N, Wilhelm C, Steinmann J, Pietschmann T, Steinmann E (2013) Transmission of Hepatitis C virus among people who inject drugs: viral stability and association with drug preparation equipment. J Infect Dis 207(2): 281-287.

    • Doerrbecker J., Meuleman P., Kang J., Riebesehl N., Wilhelm C., Friesland M., Pfaender S., Steinmann J., Pietschmann T., Steinmann E. (2013) Thermostability of seven hepatitis C virus genotypes in vitro and in vivo. J Virol Hepat 20(7): 478-485.

    • Eggenschwiler R, Loya K, Wu G, Sharma AD, Sgodda M, Zychlinski D, Herr C, Steinemann D, Teckman J, Bals R, Ott M, Schambach A, Scholer HR, Cantz T (2013) Sustained Knockdown of a Disease-Causing Gene in Patient-Specific Induced Pluripotent Stem Cells Using Lentiviral Vector-Based Gene Therapy. Stem Cells Transl Med 2(9): 641-654. * ebenfalls TWINCORE Beteiligung.

    • Eichler HG, Bloechl-Daum B, Brasseur D, Breckenridge A, Leufkens H, Raine J, Salmonson T, Schneider CK, Rasi G (2013) The risks of risk aversion in drug regulation. Nat Rev Drug Discov 12(12): 907-916.

    • Elsaman AM, Radwan AR, Akmatov MK, Della Beffa C, Walker A, Mayer CT, Dai L, Nativ S, Rygg M, Atsali E, Saijo K, Ogdie AR, Srinivasulu N, Fathi N, Ralph Schumacher H, Pessler F (2013) Amyloid arthropathy associated with multiple myeloma: A systematic analysis of 101 reported cases. Semin Arthritis Rheum 43(3): 405-412.

    • Elsaman AM, Radwan AR, Akmatov MK, Della Beffa C, Walker A, Mayer CT, Dai L, Nativ S, Rygg M, Atsali E, Saijo K, Ogdie AR, Srinivasulu N, Fathi N, Ralph Schumacher H, Pessler F (2013) Amyloid arthropathy associated with multiple myeloma: A systematic analysis of 101 reported cases. Semin Arthritis Rheum 43(3): 405-412.

    • Fernandez MA, Yu U, Zhang G, White R, Sparwasser T, Alexander SI, Jones CA (2013) Treg depletion attenuates the severity of skin disease from ganglionic spread after HSV-2 flank infection. Virology 447(1-2): 9-20.

    • Gentzsch J, Brohm C, Steinmann E, Friesland M, Menzel N, Vieyres G, Perin PM, Frentzen A, Kaderali L, Pietschmann T (2013) Hepatitis C Virus p7 is Critical for Capsid Assembly and Envelopment. PLoS pathogens 9(5): e1003355.

    • Gerold G, Pietschmann T (2013) Hepatitis C virus NS5B polymerase primes innate immune signaling. Hepatology 57(3): 1275-1277.

    • Godeke J, Pustelny C, Haussler S (2013) Recycling of peptidyl-tRNAs by peptidyl-tRNA hydrolase counteracts Azithromycin-mediated effects on Pseudomonas aeruginosa. Antimicrob Agents Chemother 57(4): 1617-1624.

    • Goncalves Vidigal P, Schmidt D, Stehling F, Mellies U, Steinmann E, Buer J, Rath PM, Steinmann J (2013) Development of a quantitative immunofluorescence assay for detection of Stenotrophomonas maltophilia antibodies in patients with cystic fibrosis. J Cyst Fibros 12(6): 651-654.

    • Goulet ML, Olagnier D, Xu Z, Paz S, Belgnaoui SM, Lafferty EI, Janelle V, Arguello M, Paquet M, Ghneim K, Richards S, Smith A, Wilkinson P, Cameron M, Kalinke U, Qureshi S, Lamarre A, Haddad EK, Sekaly RP, Peri S, Balachandran S, Lin R, Hiscott J (2013) Systems Analysis of a RIG-I Agonist Inducing Broad Spectrum Inhibition of Virus Infectivity. PLoS pathogens 9(4): e1003298.

    • Hamming OJ, Terczynska-Dyla E, Vieyres G, Dijkman R, Jorgensen SE, Akhtar H, Siupka P, Pietschmann T, Thiel V, Hartmann R (2013) Interferon lambda 4 signals via the IFNlambda receptor to regulate antiviral activity against HCV and coronaviruses. Embo J 32(23): 3055-3065.

    • Haussler S, Fuqua C (2013) Biofilms 2012: New Discoveries and Significant Wrinkles in a Dynamic Field. J Bacteriol 195(13): 2947-2958.

    • Hesse C, Ginter W, Forg T, Mayer CT, Baru AM, Arnold-Schrauf C, Unger WW, Kalay H, van Kooyk Y, Berod L, Sparwasser T (2013) In vivo targeting of human DC-SIGN drastically enhances CD8 T-cell-mediated protective immunity. Eur J Immunol 43(10): 2543-2553.

    • Hogner K, Wolff T, Pleschka S, Plog S, Gruber AD, Kalinke U, Walmrath HD, Bodner J, Gattenlohner S, Lewe-Schlosser P, Matrosovich M, Seeger W, Lohmeyer J, Herold S (2013) Macrophage-expressed IFN-beta Contributes to Apoptotic Alveolar Epithelial Cell Injury in Severe Influenza Virus Pneumonia. PLoS Pathog 9(2): e1003188.

    • Hogner K, Wolff T, Pleschka S, Plog S, Gruber AD, Kalinke U, Walmrath HD, Bodner J, Gattenlohner S, Lewe-Schlosser P, Matrosovich M, Seeger W, Lohmeyer J, Herold S (2013) Correction: Macrophage-expressed IFN-beta Contributes to Apoptotic Alveolar Epithelial Cell Injury in Severe Influenza Virus Pneumonia. PLoS Pathog 12(6): e1005716.

    • Hu M, Wang C, Zhang G, Saito M, Wang Y, Fernandez M, Qian Y, Wang Y, Sawyer A, Hawthorne W, Jones C, Sparwasser T, Bishop A, Sharland A, O'Connell P, Alexander S (2013) Graft Infiltrating Foxp3 Tregs in Spontaneously Tolerant Renal A Allografts Express High Levels of CXCR3 and BLIMP-1. Am J Transplant 13(11): 2819-2830.

    • Joshi R, Feldmann V, Koestner W, Detje C, Gottschalk S, Mayer HA, Sauer MG, Engelmann J (2013) Multifunctional silica nanoparticles for optical and magnetic resonance imaging. Biol Chem 394(1): 125-135.

    • Kanjarawi R, Dy M, Bardel E, Sparwasser T, Dubois B, Mecheri S, Kaiserlian D (2013) Regulatory CD4(+)Foxp3(+) T Cells Control the Severity of Anaphylaxis. PLoS One 8(7): e69183.

    • Kleinschnitz C, Kraft P, Dreykluft A, Hagedorn I, Gobel K, Schuhmann MK, Langhauser F, Helluy X, Schwarz T, Bittner S, Mayer CT, Brede M, Varallyay C, Pham M, Bendszus M, Jakob P, Magnus T, Meuth SG, Iwakura Y, Zernecke A, Sparwasser T, Nieswandt B, Stoll G, Wiendl H (2013) Regulatory T cells are strong promoters of acute ischemic stroke in mice by inducing dysfunction of the cerebral microvasculature. Blood 121(4): 679-691.

    • Klingenberg R, Gerdes N, Badeau RM, Gistera A, Strodthoff D, Ketelhuth DF, Lundberg AM, Rudling M, Nilsson SK, Olivecrona G, Zoller S, Lohmann C, Luscher TF, Jauhiainen M, Sparwasser T, Hansson GK (2013) Depletion of FOXP3+ regulatory T cells promotes hypercholesterolemia and atherosclerosis. J Clin Invest 123(3): 1323-1334.

    • Kuhlhorn F, Rath M, Schmoeckel K, Cziupka K, Nguyen HH, Hildebrandt P, Hunig T, Sparwasser T, Huehn J, Potschke C, Broker BM (2013) Foxp3(+) regulatory T cells are required for recovery from severe sepsis. PLoS One 8(5): e65109.

    • Layland LE, Straubinger K, Ritter M, Loffredo-Verde E, Garn H, Sparwasser T, Prazeres da Costa C (2013) Schistosoma mansoni-Mediated Suppression of Allergic Airway Inflammation Requires Patency and Foxp3(+) Treg Cells. PLoS Negl Trop Dis 7(8): e2379.

    • Lodermeyer V, Suhr K, Schrott N, Kolbe C, Sturzel CM, Krnavek D, Munch J, Dietz C, Waldmann T, Kirchhoff F, Goffinet C (2013) 90K, an interferon-stimulated gene product, reduces the infectivity of HIV-1. Retrovirology 10(1): 111.

    • Martin B, Auffray C, Delpoux A, Pommier A, Durand A, Charvet C, Yakonowsky P, de Boysson H, Bonilla N, Audemard A, Sparwasser T, Salomon BL, Malissen B, Lucas B (2013) Highly self-reactive naive CD4 T cells are prone to differentiate into regulatory T cells. Nat Commun 4(n/a): 2209.

    • Mayer CT, Huntenburg J, Nandan A, Schmitt E, Czeloth N, Sparwasser T (2013) CD4 blockade directly inhibits mouse and human CD4 T cell functions independent of Foxp3 Tregs. J Autoimmun 47(n/a): 73-82.

    • Melchiorri D, Pani L, Gasparini P, Cossu G, Ancans J, Borg JJ, Drai C, Fiedor P, Flory E, Hudson I, Leufkens HG, Muller-Berghaus J, Narayanan G, Neugebauer B, Pokrotnieks J, Robert JL, Salmonson T, Schneider CK (2013) Regulatory evaluation of Glybera in Europe - two committees, one mission. Nat Rev Drug Discov 12(9): 719.

    • Nandakumar R, Finsterbusch K, Lipps C, Neumann B, Grashoff M, Nair S, Hochnadel I, Lienenklaus S, Wappler I, Steinmann E, Hauser H, Pietschmann T, Kroger A (2013) Hepatitis C Virus Replication in Mouse Cells is Restricted by IFN-Dependent and -Independent Mechanisms. Gastroenterology 145(6): 1414-1423e1.

    • Norenberg A, Heinz S, Scheller K, Hewitt NJ, Braspenning J, Ott M (2013) Optimization of upcyte human hepatocytes for the in vitro micronucleus assay. Mutat Res 758(1-2): 69-79 * ebenfalls TWINCORE Beteiligung.

    • Pasquet L, Douet JY, Sparwasser T, Romagnoli P, van Meerwijk JP (2013) Long term prevention of chronic allograft rejection by regulatory T cell immunotherapy involves host Foxp3-expressing T cells. Blood 121(21): 4303-4310.

    • Petzold C, Riewaldt J, Watts D, Sparwasser T, Schallenberg S, Kretschmer K (2013) Foxp3(+) regulatory T cells in mouse models of type 1 diabetes. J Diabetes Res 2013(n/a): 940710.

    • Pfaender S, Heyden J, Friesland M, Ciesek S, Ejaz A, Steinmann J, Malarski A, Stoiber H, Tsiavaliaris G, Bader W, Jahreis G, Pietschmann T, Steinmann E (2013) Inactivation of Hepatitis C Virus Infectivity by Human Breast Milk. J Infect Dis 208(12): 1943-1952.

    • Prete F, Catucci M, Labrada M, Gobessi S, Castiello MC, Bonomi E, Aiuti A, Vermi W, Cancrini C, Metin A, Hambleton S, Bredius R, Notarangelo LD, van der Burg M, Kalinke U, Villa A, Benvenuti F (2013) Wiskott-Aldrich syndrome protein-mediated actin dynamics control type-I interferon production in plasmacytoid dendritic cells. J Exp Med 210(2): 355-374.

    • Preusse M, Tantawy MA, Klawonn F, Schughart K, Pessler F (2013) Infection- and procedure-dependent effects on pulmonary gene expression in the early phase of influenza A virus infection in mice. BMC Microbiol 13(n/a): 293.

    • Pustelny C, Brouwer S, Musken M, Bielecka A, Dotsch A, Nimtz M, Haussler S (2013) The peptide chain release factor methyltransferase PrmC is essential for pathogenicity and environmental adaptation of Pseudomonas aeruginosa PA14. Environ Microbiol 15(2): 597-609.

    • Puttur F, Arnold-Schrauf C, Lahl K, Solmaz G, Lindenberg M, Mayer CT, Gohmert M, Swallow M, van Helt C, Schmitt H, Nitschke L, Lambrecht BN, Lang R, Messerle M, Sparwasser T (2013) Absence of Siglec-H in MCMV Infection Elevates Interferon Alpha Production but Does Not Enhance Viral Clearance. PLoS Pathog 9(9): e1003648.

    • Rittelmeyer I, Rothe M, Brugman MH, Iken M, Schambach A, Manns MP, Baum C, Modlich U, Ott M (2013) Hepatic lentiviral gene transfer is associated with clonal selection, but not with tumor formation in serially transplanted rodents. Hepatology 58(1): 397-408.

    • Rosalia RA, Stepanek I, Pollakova V, Simova J, Bieblova J, Indrova M, Moravcova S, Pribylova H, Bontkes HJ, Bubenik J, Sparwasser T, Reinis M (2013) Administration of anti-CD25 mAb leads to impaired alpha-galactosylceramide-mediated induction of IFN-gamma production in a murine model. Immunobiology 218(6): 851-859.

    • Schemuth H, Dittmer S, Lackner M, Sedlacek L, Hamprecht A, Steinmann E, Buer J, Rath PM, Steinmann J (2013) In vitro activity of colistin as single agent and in combination with antifungals against filamentous fungi occurring in patients with cystic fibrosis. Mycoses 56(3): 297-303.

    • Schmitz I, Schneider C, Frohlich A, Frebel H, Christ D, Leonard WJ, Sparwasser T, Oxenius A, Freigang S, Kopf M (2013) IL-21 Restricts Virus-driven Treg Cell Expansion in Chronic LCMV Infection. PLoS Pathog 9(5): e1003362.

    • Schneider CK (2013) Biosimilars in rheumatology: the wind of change. Ann Rheum Dis 72(3): 315-318.

    • Sgodda M, Mobus S, Hoepfner J, Sharma AD, Schambach A, Greber B, Ott M, Cantz T (2013) Improved Hepatic Differentiation Strategies for Human Induced Pluripotent Stem Cells. Curr Mol Med 13(5): 842-855.

    • Siegfried A, Berchtold S, Manncke B, Deuschle E, Reber J, Ott T, Weber M, Kalinke U, Hofer MJ, Hatesuer B, Schughart K, Gailus-Durner V, Fuchs H, Hrabe de Angelis M, Weber F, Hornef MW, Autenrieth IB, Bohn E (2013) IFIT2 Is an Effector Protein of Type I IFN-Mediated Amplification of Lipopolysaccharide (LPS)-Induced TNF-alpha Secretion and LPS-Induced Endotoxin Shock. J Immunol 191(7): 3913-3921.

    • Steinmann E, Doerrbecker J, Friesland M, Riebesehl N, Ginkel C, Hillung J, Gentzsch J, Lauber C, Brown R, Frentzen A, Pietschmann T (2013) Characterization of hepatitis C virus intra- and inter-genotypic chimeras reveals a role of the glycoproteins in virus envelopment. J Virol 87(24): 13297-13306.

    • Steinmann E, Gravemann U, Friesland M, Doerrbecker J, Muller TH, Pietschmann T, Seltsam A (2013) Two pathogen reduction technologies-methylene blue plus light and shortwave ultraviolet light-effectively inactivate hepatitis C virus in blood products. Transfusion 53(5): 1010-1018.

    • Steinmann E, Pietschmann T (2013) Cell culture systems for hepatitis C virus. Curr Top Microbiol Immunol 369(n/a): 17-48.

    • Steinmann J, Becker B, Bischoff B, Magulski T, Steinmann E (2013) Virucidal activity of Formulation I of the World Health Organization's alcohol-based handrubs: impact of changes in key ingredient levels and test parameters. Antimicrob Resist Infect Control 2(1): 34.

    • Steinmann J, Buer J, Pietschmann T, Steinmann E (2013) Anti-infective properties of Epigallocatechin-3-gallate (EGCG), a component of Green Tea. Br J Pharmacol 168(5): 1059-1073.

    • Tsiftsoglou AS, Ruiz S, Schneider CK (2013) Development and regulation of biosimilars: current status and future challenges. BioDrugs 27(3): 203-211.

    • Vestergaard HT, Apote LD, Schneider CK, Herberts C (2013) The evolution of nonclinical regulatory science: advanced therapy medicinal products as a paradigm. Mol Ther 21(7): 1294-1296.

    • Vieyres G, Brohm C, Friesland M, Gentzsch J, Wolk B, Roingeard P, Steinmann E, Pietschmann T (2013) Subcellular localization and function of an epitope-tagged p7 in hepatitis C virus-producing cells. J Virol 87(3): 1664-1678.

    • Vieyres G, Pietschmann T (2013) Entry and replication of recombinant hepatitis C viruses in cell culture. Methods 59(2): 233-248.

    • Westhaus S, Bankwitz D, Ernst S, Rohrmann K, Wappler I, Agne C, Luchtefeld M, Schieffer B, Sarrazin C, Manns MP, Pietschmann T, Ciesek S, von Hahn T (2013) Characterization of the inhibition of hepatitis C virus entry by in vitro generated and patient derived oxidized low density lipoprotein. Hepatology 57(5): 1716-1724.

    • Worthington JJ, Klementowicz JE, Rahman S, Czajkowska BI, Smedley C, Waldmann H, Sparwasser T, Grencis RK, Travis MA (2013) Loss of the TGFbeta-Activating Integrin alphavbeta8 on Dendritic Cells Protects Mice from Chronic Intestinal Parasitic Infection via Control of Type 2 Immunity. PLoS Pathog 9(10): e1003675.

    • Wuestefeld T, Pesic M, Rudalska R, Dauch D, Longerich T, Kang TW, Yevsa T, Heinzmann F, Hoenicke L, Hohmeyer A, Potapova A, Rittelmeier I, Jarek M, Geffers R, Scharfe M, Klawonn F, Schirmacher P, Malek NP, Ott M, Nordheim A, Vogel A, Manns MP, Zender L (2013) A Direct In Vivo RNAi Screen Identifies MKK4 as a Key Regulator of Liver Regeneration. Cell 153(2): 389-401.

    • Yuan Q, Loya K, Rani B, Mobus S, Balakrishnan A, Lamle J, Cathomen T, Vogel A, Manns MP, Ott M, Cantz T, Sharma AD (2013) MicroRNA-221 overexpression accelerates hepatocyte proliferation during liver regeneration. Hepatology 57(1): 299-310.

    • Zahid MN, Turek M, Xiao F, Thi VL, Guerin M, Fofana I, Bachellier P, Thompson J, Delang L, Neyts J, Bankwitz D, Pietschmann T, Dreux M, Cosset FL, Grunert F, Baumert TF, Zeisel MB (2013) The post-binding activity of scavenger receptor BI mediates initiation of hepatitis C virus infection and viral dissemination. Hepatology 57(2): 492-504.

    2012

    • Abel S, Luckheide N, Westendorf AM, Geffers R, Roers A, Muller W, Sparwasser T, Matuschewski K, Buer J, Hansen W (2012) Strong Impact of CD4+Foxp3+ Regulatory T Cells and Limited Effect of T Cell-Derived IL-10 on Pathogen Clearance during Plasmodium yoelii Infection. J Immunol 188(11): 5467-5477.

    • Auriemma M, Brzoska T, Klenner L, Kupas V, Goerge T, Voskort M, Zhao Z, Sparwasser T, Luger TA, Loser K (2012) alpha-MSH-Stimulated Tolerogenic Dendritic Cells Induce Functional Regulatory T Cells and Ameliorate Ongoing Skin Inflammation. J Invest Dermatol 132(7): 1814-1824.

    • Bache C, Spreitzer I, Becker B, Loeschner B, Rosskopf U, Hanschmann KM, Schwanig M, Schneider CK, Lieb B, Montag T (2012) Bordetella Pertussis Toxin does not induce the release of pro-inflammatory cytokines in human whole blood. Med Microbiol Immunol 201(3): 327-335.

    • Baranek T, Manh TP, Alexandre Y, Maqbool MA, Cabeza JZ, Tomasello E, Crozat K, Bessou G, Zucchini N, Robbins SH, Vivier E, Kalinke U, Ferrier P, Dalod M (2012) Differential responses of immune cells to type I interferon contribute to host resistance to viral infection. Cell Host Microbe 12(4): 571-584.

    • Barbier J, Wegner J, Benson S, Gentzsch J, Pietschmann T, Kirschning A (2012) Total Synthesis of a Noricumazole A Library and Evaluation of HCV Inhibition. Chemistry 18(29): 9083-9090.

    • Baru AM, Ganesh V, Krishnaswamy JK, Hesse C, Untucht C, Glage S, Behrens G, Mayer CT, Puttur F, Sparwasser T (2012) Absence of Foxp3(+) Regulatory T Cells during Allergen Provocation Does Not Exacerbate Murine Allergic Airway Inflammation. PLoS One 7(10): e47102.

    • Baru AM, Untucht C, Ganesh V, Hesse C, Mayer CT, Sparwasser T (2012) Optimal Isolation of Functional Foxp3(+) Induced Regulatory T Cells Using DEREG Mice. PLoS One 7(9): e44760.

    • Berod L, Puttur F, Huehn J, Sparwasser T (2012) Tregs in infection and vaccinology: heroes or traitors?. Microb Biotechnol 5(2): 260-269.

    • Bieback K, Wuchter P, Besser D, Franke W, Becker M, Ott M, Pacher M, Ma N, Stamm C, Kluter H, Muller A, Ho AD (2012) Mesenchymal stromal cells (MSCs): science and f(r)iction. J Mol Med (Berl) 90(7): 773-782.

    • Bielecki P, Lukat P, Husecken K, Dotsch A, Steinmetz H, Hartmann RW, Muller R, Haussler S (2012) Mutation in Elongation Factor G Confers Resistance to the Antibiotic Argyrin in the Opportunistic Pathogen Pseudomonas aeruginosa. Chembiochem 13(16): 2339-2345.

    • Cervantes-Barragan L, Firner S, Bechmann I, Waisman A, Lahl K, Sparwasser T, Thiel V, Ludewig B (2012) Regulatory T cells selectively preserve immune privilege of self-antigens during viral central nervous system infection. J Immunol 188(8): 3678-3685.

    • Chhatwal P, Bankwitz D, Gentzsch J, Frentzen A, Schult P, Lohmann V, Pietschmann T (2012) Bile Acids Specifically Increase Hepatitis C Virus RNA-Replication. PloS One 7(4): e36029.

    • Dotsch A, Eckweiler D, Schniederjans M, Zimmermann A, Jensen V, Scharfe M, Geffers R, Haussler S (2012) The Pseudomonas aeruginosa transcriptome in planktonic cultures and static biofilms using RNA sequencing. PloS One 7(2): e31092.

    • Duvel J, Bertinetti D, Moller S, Schwede F, Morr M, Wissing J, Radamm L, Zimmermann B, Genieser HG, Jansch L, Herberg FW, Haussler S (2012) A chemical proteomics approach to identify c-di-GMP binding proteins in Pseudomonas aeruginosa. J Microbiol Methods 88(2): 229-236.

    • Eberlein J, Davenport B, Nguyen TT, Victorino F, Sparwasser T, Homann D (2012) Multiple layers of CD80/86-dependent costimulatory activity regulate primary, memory, and secondary lymphocytic choriomeningitis virus-specific T cell immunity. J Virol 86(4): 1955-1970.

    • Ejaz A, Steinmann E, Banki Z, Anggakusuma, Khalid S, Lengauer S, Wilhelm C, Zoller H, Schloegl A, Steinmann J, Grabski E, Kleines M, Pietschmann T, Stoiber H (2012) Specific acquisition of functional CD59 but not CD46 or CD55 by hepatitis C virus. PLoS One 7(9): e45770.

    • Ejaz A, Steinmann E, Banki Z, Kusuma A, Khalid S, Lengauer S, Wilhelm C, Zoller H, Schloegl A, Steinmann J, Grabski E, Kleines M, Pietschmann T, Stoiber H (2012) Specific Acquisition of Functional CD59 but Not CD46 or CD55 by Hepatitis C Virus. PLoS One 7(9): e45770.

    • Fofana I, Fafi-Kremer S, Carolla P, Fauvelle C, Zahid MN, Turek M, Heydmann L, Cury K, Hayer J, Combet C, Cosset FL, Pietschmann T, Hiet MS, Bartenschlager R, Habersetzer F, Doffoel M, Keck ZY, Foung SK, Zeisel MB, Stoll-Keller F, Baumert TF (2012) Mutations that Alter Use of Hepatitis C Virus Cell Entry Factors Mediate Escape from Neutralizing Antibodies. Gastroenterology 143(1): 223-233.e9.

    • Frentzen A, Hueging K, Bitzegeio J, Pietschmann T, Steinmann E (2012) Two methods of heterokaryon formation to discover HCV restriction factors. J Vis Exp n/a(65): e4029.

    • Fyhrquist N, Lehtimaki S, Lahl K, Savinko T, Lappetelainen AM, Sparwasser T, Wolff H, Lauerma A, Alenius H (2012) Foxp3+ cells control th2 responses in a murine model of atopic dermatitis. J Invest Dematol 132(6): 1672-1680.

    • Gomez de Aguero M, Vocanson M, Hacini-Rachinel F, Taillardet M, Sparwasser T, Kissenpfennig A, Malissen B, Kaiserlian D, Dubois B (2012) Langerhans cells protect from allergic contact dermatitis in mice by tolerizing CD8+ T cells and activating Foxp3+ regulatory T cells. J Clin Invest 122(5): 1700-1711.

    • Haid S, Novodomska A, Gentzsch J, Grethe C, Geuenich S, Bankwitz D, Chhatwal P, Jannack B, Hennebelle T, Bailleul F, Keppler OT, Ponisch M, Bartenschlager R, Hernandez C, Lemasson M, Rosenberg A, Wong-Staal F, Davioud-Charvet E, Pietschmann T (2012) A Plant-Derived Flavonoid Inhibits Entry of All HCV Genotypes Into Human Hepatocytes. Gastroenterology 143(1): 213-222.e5.

    • Hansen W, Hutzler M, Abel S, Alter C, Stockmann C, Kliche S, Albert J, Sparwasser T, Sakaguchi S, Westendorf AM, Schadendorf D, Buer J, Helfrich I (2012) Neuropilin 1 deficiency on CD4+Foxp3+ regulatory T cells impairs mouse melanoma growth. J Exp Med 209(11): 2001-2016.

    • Hansen W, Hutzler M, Abel S, Stockmann C, Albert J, Sparwasser T, Sakaguchi S, Westendorf A, Schadendorf D, Buer J, Helfrich I (2012) Neuropilin-1 deficiency on CD4+Foxp3+regulatory T cells impaires tumor growth in melanoma. Exp Dermatol 22(3): E38-E38.

    • Hellingman AA, van der Vlugt LE, Lijkwan MA, Bastiaansen AJ, Sparwasser T, Smits HH, Hamming JF, Quax PH (2012) A limited role for regulatory T cells in post-ischemic neovascularization. J Cell Mol Med 16(2): 328-336.

    • Kafert-Kasting S, Schneider A, Attaran M, Priesner C, Barthold M, Perrier AL, Kriegbaum H, Ott M, Meyburg J (2012) Safety assessment of intraportal liver cell application in New Zealand white rabbits under GLP conditions. Arch Toxicol 86(9): 1413-1422.

    • Kalinke U, Prinz M (2012) Endogenous, or therapeutically induced, type I interferon responses differentially modulate Th1/Th17-mediated autoimmunity in the CNS. Immunol Cell Biol 90(5): 505-509.

    • Kernbauer E, Maier V, Stoiber D, Strobl B, Schneckenleithner C, Sexl V, Reichart U, Reizis B, Kalinke U, Jamieson A, Mueller M, Decker T (2012) Conditional Stat1 Ablation Reveals the Importance of Interferon Signaling for Immunity to Listeria monocytogenes Infection. PLoS Pathog 8(6): e1002763.

    • Komor U, Bielecki P, Loessner H, Rohde M, Wolf K, Westphal K, Weiss S, Haussler S (2012) Biofilm formation by Pseudomonas aeruginosa in solid murine tumors - a novel model system. Microbes Infect 14(11): 951-958.

    • Kremer M, Suezer Y, Volz A, Frenz T, Majzoub M, Hanschmann KM, Lehmann MH, Kalinke U, Sutter G (2012) Critical role of perforin-dependent CD8+ T cell immunity for rapid protective vaccination in a murine model for human smallpox. PLoS pathogens 8(3): e1002557.

    • Krishnaswamy JK, Jirmo AC, Baru AM, Ebensen T, Guzman CA, Sparwasser T, Behrens GM (2012) TLR2 Agonist-Allergen Coupling Efficiently Redirects Th2 Cell Responses and Inhibits Allergic Airway Eosinophilia. Am J Respir Cell Mol Biol 47(6): 852-863.

    • Kugler J, Schmelz S, Gentzsch J, Haid S, Pollmann E, van den Heuvel J, Franke R, Pietschmann T, Heinz DW, Collins J (2012) High affinity peptide inhibitors of the hepatitis C virus NS3-4A protease refractory to common resistant mutants. J Biol Chem 287(46): 39224-39232.

    • Lehtimaeki S, Savinko T, Lahl K, Sparwasser T, Wolff H, Lauerma A, Alenius H, Fyhrquist N (2012) The Temporal and Spatial Dynamics of Foxp3+ Treg Cell-Mediated Suppression during Contact Hypersensitivity Responses in a Murine Model. J Invest Dermatol 132(12): 2744-2751.

    • Loebbermann J, Thornton H, Durant L, Sparwasser T, Webster KE, Sprent J, Culley FJ, Johansson C, Openshaw PJ (2012) Regulatory T cells expressing granzyme B play a critical role in controlling lung inflammation during acute viral infection. Mucosal Immunol 5(2): 161-172.

    • Lu C, Kirsch B, Zimmer C, de Jong JC, Henn C, Maurer CK, Musken M, Haussler S, Steinbach A, Hartmann RW (2012) Discovery of antagonists of PqsR, a key player in 2-alkyl-4-quinolone-dependent quorum sensing in Pseudomonas aeruginosa. Chem Biol 19(3): 381-390.

    • Maazi H, Shirinbak S, Willart M, Hammad HM, Cabanski M, Boon L, Ganesh V, Baru AM, Hansen G, Lambrecht BN, Sparwasser T, Nawijn MC, van Oosterhout AJ (2012) Contribution of regulatory T cells to alleviation of experimental allergic asthma after specific immunotherapy. Clin Exp Allergy 42(10): 1519-1528.

    • Maciulaitis R, D'Apote L, Buchanan A, Pioppo L, Schneider CK (2012) Clinical development of advanced therapy medicinal products in europe: evidence that regulators must be proactive. Mol Ther 20(3): 479-482.

    • Malone JG, Jaeger T, Manfredi P, Dotsch A, Blanka A, Bos R, Cornelis GR, Haussler S, Jenal U (2012) The YfiBNR Signal Transduction Mechanism Reveals Novel Targets for the Evolution of Persistent Pseudomonas aeruginosa in Cystic Fibrosis Airways. PLoS Pathog 8(6): e1002760.

    • Mayer CT, Berod L, Sparwasser T (2012) Layers of dendritic cell-mediated T cell tolerance, their regulation and the prevention of autoimmunity. Front Immunol 3(n/a): 183.

    • Mayer CT, Kuhl AA, Loddenkemper C, Sparwasser T (2012) Lack of Foxp3+ macrophages in both untreated and B16 melanoma-bearing mice. Blood 119(5): 1314-1315.

    • Menzel N, Fischl W, Hueging K, Bankwitz D, Frentzen A, Haid S, Gentzsch J, Kaderali L, Bartenschlager R, Pietschmann T (2012) MAP-Kinase Regulated Cytosolic Phospholipase A2 Activity Is Essential for Production of Infectious Hepatitis C Virus Particles. PLoS Pathog 8(7): e1002829.

    • Mizutani T, Neugebauer N, Putz EM, Moritz N, Simma O, Zebedin-Brandl E, Gotthardt D, Warsch W, Eckelhart E, Kantner HP, Kalinke U, Lienenklaus S, Weiss S, Strobl B, Muller M, Sexl V, Stoiber D (2012) Conditional IFNAR1 ablation reveals distinct requirements of Type I IFN signaling for NK cell maturation and tumor surveillance. Oncoimmunology 1(7): 1027-1037.

    • Navid F, Boniotto M, Walker C, Ahrens K, Proksch E, Sparwasser T, Muller W, Schwarz T, Schwarz A (2012) Induction of regulatory T cells by a murine beta-defensin. J Immunol 188(2): 735-743.

    • Ohkura N, Hamaguchi M, Morikawa H, Sugimura K, Tanaka A, Ito Y, Osaki M, Tanaka Y, Yamashita R, Nakano N, Huehn J, Fehling HJ, Sparwasser T, Nakai K, Sakaguchi S (2012) T cell receptor stimulation-induced epigenetic changes and foxp3 expression are independent and complementary events required for treg cell development. Immunity 37(5): 785-799.

    • Pace L, Tempez A, Arnold-Schrauf C, Lemaitre F, Bousso P, Fetler L, Sparwasser T, Amigorena S (2012) Regulatory T cells increase the avidity of primary CD8+ T cell responses and promote memory. Science 338(6106): 532-536.

    • Panzer M, Sitte S, Wirth S, Drexler I, Sparwasser T, Voehringer D (2012) Rapid in vivo conversion of effector T cells into Th2 cells during helminth infection. J Immunol 188(2): 615-623.

    • Puppi J, Strom SC, Hughes RD, Bansal S, Castell JV, Dagher I, Ellis EC, Nowak G, Ericzon BG, Fox IJ, Gomez-Lechon MJ, Guha C, Gupta S, Mitry RR, Ohashi K, Ott M, Reid LM, Roy-Chowdhury J, Sokal E, Weber A, Dhawan A (2012) Improving the techniques for human hepatocyte transplantation: report from a consensus meeting in London. Cell Transplant 21(1): 1-10.

    • Rath PM, Saner F, Paul A, Lehmann N, Steinmann E, Buer J, Steinmann J (2012) Multiplex PCR for rapid and improved diagnosis of bloodstream infections in liver transplant recipients. J Clin Microbiol 50(6): 2069-2071.

    • Reuter D, Sparwasser T, Hunig T, Schneider-Schaulies J (2012) Foxp3+ regulatory T cells control persistence of viral CNS infection. PloS One 7(3): e33989.

    • Rothe M, Rittelmeyer I, Iken M, Rudrich U, Schambach A, Glage S, Manns MP, Baum C, Bock M, Ott M, Modlich U (2012) Epidermal growth factor improves lentivirus vector gene transfer into primary mouse hepatocytes. Gene Ther 19(4): 425-434.

    • Ruhl M, Chhatwal P, Strathmann H, Kuntzen T, Bankwitz D, Skibbe K, Walker A, Heinemann FM, Horn PA, Allen TM, Hoffmann D, Pietschmann T, Timm J (2012) Escape from a dominant HLA-B*15-restricted CD8+ T cell response against hepatitis C virus requires compensatory mutations outside the epitope. J Virol 86(2): 991-1000.

    • Sandmann L, Wilson M, Back D, Wedemeyer H, Manns MP, Steinmann E, Pietschmann T, von Hahn T, Ciesek S (2012) Antiretroviral drugs do not facilitate hepatitis C virus (HCV) infection in vitro. Antiviral Res 96(1): 51-58.

    • Schallenberg S, Petzold C, Tsai PY, Sparwasser T, Kretschmer K (2012) Vagaries of fluorochrome reporter gene expression in foxp3(+) regulatory T cells. PLoS One 7(8): e41971.

    • Schneider CK, Borg JJ, Ehmann F, Ekman N, Heinonen E, Ho K, Hoefnagel MH, van der Plas RM, Ruiz S, van der Stappen AJ, Thorpe R, Tiitso K, Tsiftsoglou AS, Vleminckx C, Waxenecker G, Welin M, Weise M, Trouvin JH (2012) In support of the European Union biosimilar framework. Nat Biotechnol 30(8): 745-748.

    • Schneider CK, Vleminckx C, Gravanis I, Ehmann F, Trouvin JH, Weise M, Thirstrup S (2012) Setting the stage for biosimilar monoclonal antibodies. Nat Biotechnol 30(12): 1179-1185.

    • Schuster M, Glauben R, Plaza-Sirvent C, Schreiber L, Annemann M, Floess S, Kuhl AA, Clayton LK, Sparwasser T, Schulze-Osthoff K, Pfeffer K, Huehn J, Siegmund B, Schmitz I (2012) IkappaB(NS) Protein Mediates Regulatory T Cell Development via Induction of the Foxp3 Transcription Factor. Immunity 37(6): 998-1008.

    • Schwandt T, Schumak B, Gielen GH, Jungerkes F, Schmidbauer P, Klocke K, Staratschek-Jox A, van Rooijen N, Kraal G, Ludwig-Portugall I, Franken L, Wehner S, Kalff JC, Weber O, Kirschning C, Coch C, Kalinke U, Wenzel J, Kurts C, Zawatzky R, Holzmann B, Layland L, Schultze JL, Burgdorf S, den Haan JM, Knolle PA, Limmer A (2012) Expression of type I interferon by splenic macrophages suppresses adaptive immunity during sepsis. Embo J 31(1): 201-213.

    • Schwarz A, Navid F, Sparwasser T, Clausen BE, Schwarz T (2012) 1,25-Dihydroxyvitamin D Exerts Similar Immunosuppressive Effects as UVR but Is Dispensable for Local UVR-Induced Immunosuppression. J Invest Dermatol 132(12): 2762-2769.

    • Selezska K, Kazmierczak M, Musken M, Garbe J, Schobert M, Haussler S, Wiehlmann L, Rohde C, Sikorski J (2012) Pseudomonas aeruginosa population structure revisited under environmental focus: impact of water quality and phage pressure. Environ Microbiol 14(8): 1952-1967.

    • Sharma AD, Rittelmeyer I, Cantz T, Ott M (2012) Regenerative therapies for liver diseases. Stem Cell Biology and Regenerative Medicine 2013(doi: 10.1007/978-1-62703-098-4_10): 203-231.

    • Stegmann KA, Bjorkstrom NK, Ciesek S, Lunemann S, Jaroszewicz J, Wiegand J, Malinski P, Dustin LB, Rice CM, Manns MP, Pietschmann T, Cornberg M, Ljunggren HG, Wedemeyer H (2012) Interferon alpha-stimulated natural killer cells from patients with acute hepatitis C virus (HCV) infection recognize HCV-infected and uninfected hepatoma cells via DNAX accessory molecule-1. J Infect Dis 205(9): 1351-1362.

    • Steinmann J, Paulmann D, Becker B, Bischoff B, Steinmann E (2012) Comparison of virucidal activity of alcohol-based hand sanitizers versus antimicrobial hand soaps in vitro and in vivo. J Hosp Infect 82(4): 277-280.

    • Storz MP, Maurer CK, Zimmer C, Wagner N, Brengel C, de Jong JC, Lucas S, Musken M, Haussler S, Steinbach A, Hartmann RW (2012) Validation of PqsD as an Anti-biofilm Target in Pseudomonas aeruginosa by Development of Small-Molecule Inhibitors. J Am Chem Soc 134(39): 16143-16146.

    • Stross L, Gunther J, Gasteiger G, Asen T, Graf S, Aichler M, Esposito I, Busch DH, Knolle P, Sparwasser T, Protzer U (2012) Foxp3+ regulatory T cells protect the liver from immune damage and compromise virus control during acute, experimental hepatitis B virus infection. Hepatology 56(3): 873-883.

    • Veiga-Parga T, Suryawanshi A, Mulik S, Gimenez F, Sharma S, Sparwasser T, Rouse BT (2012) On the Role of Regulatory T Cells during Viral-Induced Inflammatory Lesions. J Immunol 189(12): 5924-5933.

    • Waern JM, Yuan Q, Rudrich U, Becker PD, Schulze K, Strick-Marchand H, Huntington ND, Zacher BJ, Wursthorn K, Di Santo JP, Guzman CA, Manns MP, Ott M, Bock M (2012) Ectopic expression of murine CD47 minimizes macrophage rejection of human hepatocyte xenografts in immunodeficient mice. Hepatology 56(4): 1479-1788.

    • Wei Q, Minh PN, Dotsch A, Hildebrand F, Panmanee W, Elfarash A, Schulz S, Plaisance S, Charlier D, Hassett D, Haussler S, Cornelis P (2012) Global regulation of gene expression by OxyR in an important human opportunistic pathogen. Nucleic Acids Res 40(10): 4320-4333.

    • Weise M, Bielsky MC, De Smet K, Ehmann F, Ekman N, Giezen TJ, Gravanis I, Heim HK, Heinonen E, Ho K, Moreau A, Narayanan G, Kruse NA, Reichmann G, Thorpe R, van Aerts L, Vleminckx C, Wadhwa M, Schneider CK (2012) Biosimilars: what clinicians should know. Blood 120(26): 5111-5117.

    • Weissmueller S, Semmler LY, Kalinke U, Christians S, Mueller-Berghaus J, Waibler Z (2012) ICOS-LICOS interaction is critically involved in TGN1412-mediated T cell activation. Blood 119(26): 6268-6277.

    • Zaoui C, Overhage J, Lons D, Zimmermann A, Musken M, Bielecki P, Pustelny C, Becker T, Nimtz M, Haussler S (2012) An orphan sensor kinase controls quinolone signal production via MexT in Pseudomonas aeruginosa. Mol Microbiol 83(3): 536-547.

    • Zhao E, Wang L, Dai J, Kryczek I, Wei S, Vatan L, Altuwaijri S, Sparwasser T, Wang G, Keller ET, Zou W (2012) Regulatory T cells in the bone marrow microenvironment in patients with prostate cancer. Oncoimmunology 1(2): 152-161.

    • van der Vlugt LE, Labuda LA, Ozir-Fazalalikhan A, Lievers E, Gloudemans AK, Liu KY, Barr TA, Sparwasser T, Boon L, Ngoa UA, Feugap EN, Adegnika AA, Kremsner PG, Gray D, Yazdanbakhsh M, Smits HH (2012) Schistosomes induce regulatory features in human and mouse CD1d(hi) B cells: inhibition of allergic inflammation by IL-10 and regulatory T cells. PloS One 7(2): e30883.

    • von Hahn T, Schiene-Fischer C, Van ND, Pfander S, Karavul B, Steinmann E, Potthoff A, Strassburg C, Hamdi N, Abdelaziz AI, Sarrazin C, Muller T, Berg T, Trepo E, Wedemeyer H, Manns MP, Pietschmann T, Ciesek S (2012) Hepatocytes that Express Variants of Cyclophilin A are Resistant to HCV Infection and Replication. Gastroenterology 143(2): 439-447e1.

    2011

    • Arico E, Monque DM, D'Agostino G, Moschella F, Venditti M, Kalinke U, Allen DJ, Nash AA, Belardelli F, Ferrantini M (2011) MHV-68 producing mIFNalpha1 is severely attenuated in vivo and effectively protects mice against challenge with wt MHV-68.. Vaccine 29(23): 3935-3944.

    • Baru AM, Krishnaswamy JK, Rathinasamy A, Scherr M, Eder M, Behrens GM (2011) Dendritic cells derived from HOXB4-immortalized hematopoietic bone marrow cells.. Exp Biol Med (Maywood) 236(11): 1291-1297.

    • Beyer M, Thabet Y, Muller RU, Sadlon T, Classen S, Lahl K, Basu S, Zhou X, Bailey-Bucktrout SL, Krebs W, Schonfeld EA, Bottcher J, Golovina T, Mayer CT, Hofmann A, Sommer D, Debey-Pascher S, Endl E, Limmer A, Hippen KL, Blazar BR, Balderas R, Quast T, Waha A, Mayer G, Famulok M, Knolle PA, Wickenhauser C, Kolanus W, Schermer B, Bluestone JA, Barry SC, Sparwasser T, Riley JL, Schultze JL (2011) Repression of the genome organizer SATB1 in regulatory T cells is required for suppressive function and inhibition of effector differentiation.. Nat Immunol 12(9): 898-907.

    • Bielecki P, Puchalka J, Wos-Oxley ML, Loessner H, Glik J, Kawecki M, Nowak M, Tummler B, Weiss S, Dos Santos VA (2011) In-Vivo Expression Profiling of Pseudomonas aeruginosa Infections Reveals Niche-Specific and Strain-Independent Transcriptional Programs. PLos One 6(9): e24235.

    • Blankenhaus B, Klemm U, Eschbach ML, Sparwasser T, Huehn J, Kuhl AA, Loddenkemper C, Jacobs T, Breloer M (2011) Strongyloides ratti infection induces expansion of Foxp3+ regulatory T cells that interfere with immune response and parasite clearance in BALB/c mice.. J Immunol 186(7): 4295-4305.

    • Burgel B, Friesland M, Koch A, Manns MP, Wedemeyer H, Weissenborn K, Schulz-Schaeffer WJ, Pietschmann T, Steinmann E, Ciesek S (2011) Hepatitis C virus enters human peripheral neuroblastoma cells - evidence for extra-hepatic cells sustaining hepatitis C virus penetration. J Viral Hepat 18(8): 562-570.

    • Buttel IC, Chamberlain P, Chowers Y, Ehmann F, Greinacher A, Jefferis R, Kramer D, Kropshofer H, Lloyd P, Lubiniecki A, Krause R, Mire-Sluis A, Platts-Mills T, Ragheb JA, Reipert BM, Schellekens H, Seitz R, Stas P, Subramanyam M, Thorpe R, Trouvin JH, Weise M, Windisch J, Schneider CK (2011) Taking immunogenicity assessment of therapeutic proteins to the next level.. Biologicals 39(2): 100-109.

    • Cassani B, Villablanca EJ, Quintana FJ, Love PE, Lacy-Hulbert A, Blaner WS, Sparwasser T, Snapper SB, Weiner HL, Mora JR (2011) Gut-tropic T Cells that Express Integrin alpha4beta7 and CCR9 are Required for Induction of Oral Immune Tolerance in Mice.. Gastroenterology 141(6): 2109-18.

    • Chopy D, Detje CN, Lafage M, Kalinke U, Lafon M (2011) The type I interferon response bridles rabies virus infection and reduces pathogenicity.. J Neurovirol 17(4): 353-367.

    • Ciesek S, Westhaus S, Wicht M, Wappler I, Henschen S, Sarrazin C, Hamdi N, Abdelaziz AI, Strassburg CP, Wedemeyer H, Manns MP, Pietschmann T, von Hahn T (2011) Impact of intra- and interspecies variation of occludin on its function as coreceptor for authentic hepatitis C virus particles. J Virol 85(15): 7613-7621.

    • Ciesek S, von Hahn T, Colpitts CC, Schang LM, Friesland M, Steinmann J, Manns MP, Ott M, Wedemeyer H, Meuleman P, Pietschmann T, Steinmann E (2011) The green tea polyphenol epigallocatechin-3-gallate (EGCG) inhibits hepatitis C virus (HCV) entry. Hepatology 54(6): 1947-1955.

    • Ciesek S, von Hahn T, Colpitts CC, Schang LM, Friesland M, Steinmann J, Manns MP, Ott M, Wedemeyer H, Meuleman P, Pietschmann T, Steinmann E (2011) The green tea polyphenol epigallocatechin-3-gallate (EGCG) inhibits hepatitis C virus (HCV) entry.. Hepatology 54(6): 1947-1955.

    • Ciesek S, von Hahn T, Manns MP (2011) Second-wave protease inhibitors: choosing an heir. Clin Liver Dis 15(3): 597-609.

    • Dann A, Poeck H, Croxford AL, Gaupp S, Kierdorf K, Knust M, Pfeifer D, Maihoefer C, Endres S, Kalinke U, Meuth SG, Wiendl H, Knobeloch KP, Akira S, Waisman A, Hartmann G, Prinz M (2011) Cytosolic RIG-I-like helicases act as negative regulators of sterile inflammation in the CNS. Nat Neurosci 15(1): 98-106.

    • Diamond MS, Kinder M, Matsushita H, Mashayekhi M, Dunn GP, Archambault JM, Lee H, Arthur CD, White JM, Kalinke U, Murphy KM, Schreiber RD (2011) Type I interferon is selectively required by dendritic cells for immune rejection of tumors.. J Exp Med 208(10): 1989-2003.

    • Doerrbecker J, Friesland M, Ciesek S, Erichsen TJ, Mateu-Gelabert P, Steinmann J, Pietschmann T, Steinmann E (2011) Inactivation and survival of hepatitis C virus on inanimate surfaces. J Infect Dis 204(12): 1830-1838.

    • Dominguez PM, Lopez-Bravo M, Kalinke U, Ardavin C (2011) Statins inhibit iNOSmediated microbicidal potential of activated monocyte-derived dendritic cells by an IFNbeta-dependent mechanism.. Eur J Immunol 41(11): 3330-3339.

    • Eichler HG, Abadie E, Breckenridge A, Flamion B, Gustafsson LL, Leufkens H, Rowland M, Schneider CK, Bloechl-Daum B (2011) Bridging the efficacy-effectiveness gap: a regulator's perspective on addressing variability of drug response.. Nat Rev Drug Discov 10(7): 495-506.

    • Frentzen A, Huging K, Bitzegeio J, Friesland M, Haid S, Gentzsch J, Hoffmann M, Lindemann D, Zimmer G, Zielecki F, Weber F, Steinmann E, Pietschmann T (2011) Completion of hepatitis C virus replication cycle in heterokaryons excludes dominant restrictions in human non-liver and mouse liver cell lines. PLoS Pathog 7(4): e1002029.

    • Grabski E, Waibler Z, Schule S, Kloke BP, Sender LY, Panitz S, Cichutek K, Schweizer M, Kalinke U (2011) Comparative analysis of transduced primary human dendritic cells generated by the use of three different lentiviral vector systems.. Mol Biotechnol 47(3): 262-269.

    • Gratz MS, Suezer Y, Kremer M, Volz A, Majzoub M, Hanschmann KM, Kalinke U, Schwantes A, Sutter G (2011) N1L is an ectromelia virus virulence factor and essential for in vivo spread upon respiratory infection.. J Virol 85(7): 3557-3569.

    • Hackl D, Loschko J, Sparwasser T, Reindl W, Krug AB (2011) Activation of dendritic cells via TLR7 reduces Foxp3 expression and suppressive function in induced Tregs.. Eur J Immunol 41(5): 1334-1343.

    • Hadis U, Wahl B, Schulz O, Hardtke-Wolenski M, Schippers A, Wagner N, Muller W, Sparwasser T, Forster R, Pabst O (2011) Intestinal tolerance requires gut homing and expansion of FoxP3+ regulatory T cells in the lamina propria.. Immunity 34(2): 237-246.

    • Iacob R, Rudrich U, Rothe M, Kirsch S, Maasoumy B, Narain N, Verfaillie CM, Sancho-Bru P, Iken M, Popescu I, Schambach A, Manns MP, Bock M (2011) Induction of a mature hepatocyte phenotype in adult liver derived progenitor cells by ectopic expression of transcription factors.. Stem Cell Res 6(3): 251-261.

    • Kalinke U, Bechmann I, Detje CN (2011) Host strategies against virus entry via the olfactory system.. Virulence 2(4): 367-370.

    • Kang TW, Yevsa T, Woller N, Hoenicke L, Gereke M, Wuestefeld T, Dauch D, Hohmeyer A, Potapova A, Bruder D, Schirmacher P, Longerich T, Kubicka S, Ott M, Iken M, Luedde T, Rudalska R, Vucur M, Weiss S, Heikenwalder M, Khan S, Gil J, Manns MP, Tacke F (2011) Senescence surveillance of premalignant hepatocytes limits liver cancer development.. Nature 479(7374): 547-551.

    • Kastenmuller W, Gasteiger G, Subramanian N, Sparwasser T, Busch DH, Belkaid Y, Drexler I, Germain RN (2011) Regulatory T Cells Selectively Control CD8+ T Cell Effector Pool Size via IL-2 Restriction.. J Immunol 187(6): 3186-3197.

    • Koenig S, Yuan Q, Krause P, Christiansen H, Rave-Fraenk M, Kafert-Kasting S, Kriegbaum H, Schneider A, Ott M, Meyburg J (2011) Regional transient portal ischemia and irradiation as preparative regimen for hepatocyte transplantation.. Cell Transplant 20(2): 303-311.

    • Lo Re S, Lecocq M, Uwambayinema F, Yakoub Y, Delos M, Demoulin JB, Lucas S, Sparwasser T, Renauld JC, Lison D, Huaux F (2011) PDGF-Producing CD4+ Foxp3+ Regulatory T Lymphocytes Promote Lung Fibrosis.. Am J Respir Crit Care Med 184(11): 1270-1281.

    • Lochner M (2011) Tertiary lymphoid tissues in the colon: friend and foe.. Gut Microbes 2(3): 193-197.

    • Lochner M, Berard M, Sawa S, Hauer S, Gaboriau-Routhiau V, Fernandez TD, Snel J, Bousso P, Cerf-Bensussan N, Eberl G (2011) Restricted microbiota and absence of cognate TCR antigen leads to an unbalanced generation of Th17 cells. J Immunol 186(3): 1531-1537.

    • Lupberger J, Zeisel MB, Xiao F, Thumann C, zona L, Davis C, Mee CJ, Turek M, Gorke S, Royer C, Fischer B, Zahid MN, Lavillette D, Fresquet J, Cosset FL, Rothenberg SM, Pietschmann T, Patel AH, Pessaux P, Doffoel M, Raffelsberger W, Poch O, McKeating JA, Brino L, Baumert TF (2011) EGFR and EphA2 are host factors for hepatitis C virus entry and possible targets for antiviral therapy. Nat Med 17(5): 589-595.

    • Mayer CT, Floess S, Baru AM, Lahl K, Huehn J, Sparwasser T (2011) CD8+ Foxp3+ T cells share developmental and phenotypic features with classical CD4+ Foxp3+ regulatory T cells but lack potent suppressive activity. Eur J Immunol 41(3): 716-725.

    • McNally A, Hill GR, Sparwasser T, Thomas R, Steptoe RJ (2011) CD4+CD25+regulatory T cells control CD8+ T-cell effector differentiation by modulating IL-2 homeostasis.. Proc Natl Acad Sci U S A 108(18): 7529-7534.

    • Ohnmacht C, Marques R, Presley L, Sawa S, Lochner M, Eberl G (2011) Intestinal microbiota, evolution of the immune system and the bad reputation of proinflammatory immunity.. Cell Microbiol 13(5): 653-659.

    • Olivier A, Sainz-Perez A, Dong H, Sparwasser T, Majlessi L, Leclerc C (2011) The adjuvant effect of TLR agonists on CD4(+) effector T cells is under the indirect control of regulatory T cells.. Eur J Immunol 41(8): 2303-2313.

    • Onder L, Scandella E, Chai Q, Firner S, Mayer CT, Sparwasser T, Thiel V, Rülicke T, Burkhard L (2011) Assessing stromal cell antigen presentation in a novel podoplanin: Cre-recombinase BAC-transgenic mouse model.. Front Immunol 2(n/a): 50.

    • Paulmann D, Steinmann J, Becker B, Bischoff B, Steinmann E (2011) Virucidal activity of different alcohols against murine norovirus, a surrogate of human norovirus. J Hosp Infect 79(4): 378-379.

    • Reiss M, Buttel IC, Schneider CK (2011) Report from the Committee for Advanced Therapies (CAT). Pitfalls on the way from concept to medical treatment with advanced therapy medicinal products.. Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz 54(7): 822-830.

    • Sancho-Bru P, Roelandt P, Narain N, Pauwelyn K, Notelaers T, Shimizu T, Ott M, Verfaillie C (2011) Directed differentiation of murine-induced pluripotent stem cells to functional hepatocyte-like cells.. J Hepatol 54(1): 98-107.

    • Sawa S, Lochner M, Satoh-Takayama N, Dulauroy S, Berard M, Kleinschek M, Cua D, Di Santo JP, Eberl G (2011) RORgammat+ innate lymphoid cells regulate intestinal homeostasis by integrating negative signals from the symbiotic microbiota.. Nat Immunol 12(4): 320-326.

    • Schmidt J, Musken M, Becker T, Magnowska Z, Bertinetti D, Moller S, Zimmermann B, Herberg FW, Jansch L, Haussler S (2011) The Pseudomonas aeruginosa chemotaxis methyltransferase CheR1 impacts on bacterial surface sampling. PLoS One 6(3): e18184.

    • Schulke S, Burggraf M, Waibler Z, Wangorsch A, Wolfheimer S, Kalinke U, Vieths S, Toda M, Scheurer S (2011) A fusion protein of flagellin and ovalbumin suppresses the T(H)2 response and prevents murine intestinal allergy.. J Allergy Clin Immunol 128(6): 1340-1348 e1312.

    • Schwarz A, Navid F, Sparwasser T, Clausen BE, Schwarz T (2011) In vivo reprogramming of UV radiation-induced regulatory T-cell migration to inhibit the elicitation of contact hypersensitivity.. J Allergy Clin Immunol 128(4): 826-833.

    • Seung E, Cho JL, Sparwasser T, Medoff BD, Luster AD (2011) Inhibiting CXCR3-dependent CD8+ T cell trafficking enhances tolerance induction in a mouse model of lung rejection.. J Immunol 186(12): 6830-6838.

    • Sharma AD, Narain N, Handel EM, Iken M, Singhal N, Cathomen T, Manns MP, Scholer HR, Ott M, Cantz T (2011) MicroRNA-221 regulates FAS-induced fulminant liver failure.. Hepatology 53(5): 1651-1661.

    • Stagg J, Divisekera U, Duret H, Sparwasser T, Teng MW, Darcy PK, Smyth MJ (2011) CD73-deficient mice have increased antitumor immunity and are resistant to experimental metastasis.. Cancer Res 71(8): 2892-2900.

    • Steinmann E, Ciesek S, Friesland M, Erichsen TJ, Pietschmann T (2011) Prolonged Survival of Hepatitis C Virus in the Anesthetic Propofol. Clin Infect Dis 53(9): 963-964.

    • Steinmann J, Kaase M, Gatermann S, Popp W, Steinmann E, Damman M, Paul A, Saner F, Buer J, Path P (2011) Outbreak due to a Klebsiella pneumoniae strain harbouring KPC-2 and VIM-1 in a German university hospital, July 2010 to January 2011. Euro Surveill 16(33): pii: 19944.

    • Straub BK, Rickelt S, Zimbelmann R, Grund C, Kuhn C, Iken M, Ott M, Schirmacher P, Franke WW (2011) E:N-cadherin heterodimers define a novel kind of adherens junction connecting certain endoderm-derived normal and tumor cells. J Cell Biol 195(5): 873-887.

    • Tacken PJ, Ginter W, Berod L, Cruz LJ, Joosten B, Sparwasser T, Figdor CG, Cambi A (2011) Targeting DC-SIGN via its neck region leads to prolonged antigen residence in early endosomes, delayed lysosomal degradation, and cross-presentation. Blood 118(15): 4111-4119.

    • Tse BW, Russell PJ, Lochner M, Forster I, Power CA (2011) IL-18 Inhibits Growth of Murine Orthotopic Prostate Carcinomas via Both Adaptive and Innate Immune Mechanisms.. PLoS One 6(9): e24241.

    • Wei Q, Tarighi S, Dotsch A, Haussler S, Musken M, Wright VJ, Camara M, Williams P, Haenen S, Boerjan B, Bogaerts A, Vierstraete E, Verleyen P, Schoofs L, Willaert R, De Groote VN, Michiels J, Vercammen K, Crabbe A, Cornelis P (2011) Phenotypic and genome-wide analysis of an antibiotic-resistant small colony variant (SCV) of Pseudomonas aeruginosa. PLoS One 6(12): e29276.

    • Weise M, Bielsky MC, De Smet K, Ehmann F, Ekman N, Narayanan G, Heim HK, Heinonen E, Ho K, Thorpe R, Vleminckx C, Wadhwa M, Schneider CK (2011) Biosimilars-why terminology matters.. Nat Biotechnol 29(8): 690-693.

    • Weiss EM, Schmidt A, Vobis D, Garbi N, Lahl K, Mayer CT, Sparwasser T, Ludwig A, Suri-Payer E, Oberle N, Krammer PH (2011) Foxp3-mediated suppression of CD95L expression confers resistance to activation-induced cell death in regulatory T cells.. J Immunol 187(4): 1684-1691.

    • Wheeler K, Tardif S, Rival C, Luu B, Bui E, Del Rio R, Teuscher C, Sparwasser T, Hardy D, Tung KS (2011) Regulatory T cells control tolerogenic versus autoimmune response to sperm in vasectomy.. Proc Natl Acad Sci U S A 108(18): 7511-7516.

    • Wilhelm C, Hirota K, Stieglitz B, Van Snick J, Tolaini M, Lahl K, Sparwasser T, Helmby H, Stockinger B (2011) An IL-9 fate reporter demonstrates the induction of an innate IL-9 response in lung inflammation.. Nat Immunol 12(11): 1071-1077.

    • Williams SK, Fairless R, Weise J, Kalinke U, Schulz-Schaeffer W, Diem R (2011) Neuroprotective effects of the cellular prion protein in autoimmune optic neuritis.. Am J Pathol 178(6): 2823-2831.

    • Woller N, Knocke S, Mundt B, Gurlevik E, Struver N, Kloos A, Boozari B, Schache P, Manns MP, Malek NP, Sparwasser T, Zender L, Wirth TC, Kubicka S, Kuhnel F (2011) Virus-induced tumor inflammation facilitates effective DC cancer immunotherapy in a Treg-dependent manner in mice.. J Clin Invest 121(7): 2570-2582.

    • Wu G, Liu N, Rittelmeyer I, Sharma AD, Sgodda M, Zaehres H, Bleidissel M, Greber B, Gentile L, Han DW, Rudolph C, Steinemann D, Schambach A, Ott M, Scholer HR, Cantz T (2011) Generation of healthy mice from gene-corrected disease-specific induced pluripotent stem cells. PLoS Biol 9(7): e1001099.

    • von Hahn T, Schulze A, Chicano Wust I, Heidrich B, Becker T, Steinmann E, Helfritz FA, Rohrmann K, Urban S, Manns MP, Pietschmann T, Ciesek S (2011) The novel immunosuppressive protein kinase C inhibitor sotrastaurin has no pro-viral effects on the replication cycle of hepatitis B or C virus. PLoS One 6(9): e24142.

    2010

    • Kern M, Popov A, Scholz K, Schumak B, Dandji D, Limmer A, Eggle D, Sacher T, Zawatzky R, Holtappels R, Reddehase MJ, Hartmann G, Debey-Pascher S, Diehl L, Kalinke U, Koszinowski U, Schultze J, Knolle PA (2010) Virally infected mouse liver endothelial cells trigger CD8+ T-cell immunity.. Gastroenterology 138(1): 336-46.

    • Malinarich FH, Grabski E, Worbs T, Chennupati V, Haas JD, Schmitz S, Candia E, Quera R, Malissen B, Forster R, Hermoso M, Prinz I (2010) Constant TCR triggering suggests that the TCR expressed on intestinal intraepithelial gammadelta T cells is functional in vivo. Eur J Immunol 40(12): 3378-88.

    • Steinmann E, Pietschmann T (2010) Hepatitis C virus p7-a viroporin crucial for virus assembly and an emerging target for antiviral therapy. Viruses 2(9): 2078-2095 (Review).

    2008

    • Balke B, Schmoldt S, Haussler S, Suerbaum S, Heesemann J, Hogardt M (2008) A German external quality survey of diagnostic microbiology of respiratory tract infections in patients with cystic fibrosis. J Cyst Fibros 7(1): 7-14.

    • Cantz T, Manns MP, Ott M (2008) Stem cells in liver regeneration and therapy. Cell Tissue Res 331(1): 271-282 Review.

    • Ciesek S, Steinmann E, Manns MP, Wedemeyer H, Pietschmann T (2008) The suppressive effect that myriocin has on hepatitis C virus RNA replication is independent of inhibition of serine palmitoyl transferase. J Infect Dis 198(7): 1091-1093.

    • Dietrich CF, Ignee A, Braden B, Barreiros AP, Ott M, Hocke M (2008) Improved differentiation of pancreatic tumors using contrast-enhanced endoscopic ultrasound. Clin Gastroenterol Hepatol 6(5): 590-597 e1.

    • Haridass D, Narain N, Ott M (2008) Hepatocyte transplantation: waiting for stem cells. Curr Opin Organ Transplant 13(6): 627-632 Review.

    • Haussler S, Becker T (2008) The pseudomonas quinolone signal (PQS) balances life and death in Pseudomonas aeruginosa populations. PLoS Pathog 4(9): e1000166.

    • Jirasko V, Montserret R, Appel N, Janvier A, Eustachi L, Brohm C, Steinmann E, Pietschmann T, Penin F, Bartenschlager R (2008) Structural and functional characterization of nonstructural protein 2 for its role in hepatitis C virus assembly. J Biol Chem 283(42): 28546-28562.

    • Kwon HS, Ott M (2008) The ups and downs of SIRT1. Trends Biochem Sci 33(11): 517-525 Review.

    • Ott M (2008) A symphony of techniques for liver cell therapy, only applicable to rats?. J Hepatol 49(1): 6-8.

    • Pietschmann T, Steinmann E, Ciesek S (2008) Hepatitis C virus cell culture models--new perspectives for research and clinic. Dtsch Med Wochenschr 133(30): 1580-1584.

    • Sharma AD, Cantz T, Vogel A, Schambach A, Haridass D, Iken M, Bleidissel M, Manns MP, Scholer HR, Ott M (2008) Murine embryonic stem cell-derived hepatic progenitor cells engraft in recipient livers with limited capacity of liver tissue formation. Cell Transplant 17(3): 313-323.

    • Steinmann E, Brohm C, Kallis S, Bartenschlager R, Pietschmann T (2008) Efficient trans-encapsidation of hepatitis C virus RNAs into infectious virus-like particles. J Virol 82(14): 7034-7046.

    2007

    • Blakqori G, Delhaye S, Habjan M, Blair CD, Sanchez-Vargas I, Olson KE, Attarzadeh-Yazdi G, Fragkoudis R, Kohl A, Kalinke U, Weiss S, Michiels T, Staeheli P, Weber F (2007) La Crosse bunyavirus nonstructural protein NSs serves to suppress the type I interferon system of mammalian hosts. J Virol 81(10): 4991-4999.

    • Demirel O, Waibler Z, Kalinke U, Grunebach F, Appel S, Brossart P, Hasilik A, Tampe R, Abele R (2007) Identification of a lysosomal peptide transport system induced during dendritic cell development. J Biol Chem 282(52): 37836-37843.

    • Schleicher U, Liese J, Knippertz I, Kurzmann C, Hesse A, Heit A, Fischer JA, Weiss S, Kalinke U, Kunz S, Bogdan C (2007) NK cell activation in visceral leishmaniasis requires TLR9, myeloid DCs, and IL-12, but is independent of plasmacytoid DCs. J Exp Med 204(4): 893-906.

    2006

    • Aichele P, Unsoeld H, Koschella M, Schweier O, Kalinke U, Vucikuja S (2006) CD8 T cells specific for lymphocytic choriomeningitis virus require type I IFN receptor for clonal expansion. J Immunol 176(8): 4525-4529.

    • Buchholz CJ, Bach P, Nikles D, Kalinke U (2006) Prion protein-specific antibodies for therapeutic intervention of transmissible spongiform encephalopathies. Expert Opin Biol Ther 6(3): 293-300.

    • Gerlach N, Schimmer S, Weiss S, Kalinke U, Dittmer U (2006) Effects of type I interferons on Friend retrovirus infection. J Virol 80(7): 3438-3444.

    • Hinz T, Buchholz CJ, van der Stappen T, Cichutek K, Kalinke U (2006) Manufacturing and quality control of cell-based tumor vaccines: a scientific and a regulatory perspective. J Immunother 29(5): 472-476.

    • Kalinke U, Bach P, Konig M, Buchholz CJ (2006) Vaccination against prion diseases. Discov Med 6(31): 29-34.

    • Kamphuis E, Junt T, Waibler Z, Forster R, Kalinke U (2006) Type I interferons directly regulate lymphocyte recirculation and cause transient blood lymphopenia. Blood 108(10): 3253-3261.

    • Klemm S, Gutermuth J, Hultner L, Sparwasser T, Behrendt H, Peschel C, Mak TW, Jakob T, Ruland J (2006) The Bcl10-Malt1 complex segregates Fc epsilon RI-mediated nuclear factor kappa B activation and cytokine production from mast cell degranulation.. J Exp Med 203(2): 337-347.

    • Le Bon A, Durand V, Kamphuis E, Thompson C, Bulfone-Paus S, Rossmann C, Kalinke U, Tough DF (2006) Direct stimulation of T cells by type I IFN enhances the CD8+ T cell response during cross-priming. J Immunol 176(8): 4682-4689.

    • Le Bon A, Thompson C, Kamphuis E, Durand V, Rossmann C, Kalinke U, Tough DF (2006) Cutting edge: enhancement of antibody responses through direct stimulation of B and T cells by type I IFN. J Immunol 176(4): 2074-2078.

    • Ludwig H, Suezer Y, Waibler Z, Kalinke U, Schnierle BS, Sutter G (2006) Double-stranded RNA-binding protein E3 controls translation of viral intermediate RNA, marking an essential step in the life cycle of modified vaccinia virus Ankara. J Gen Virol 87(Pt 5): 1145-1155.

    • Schneider CK, Kalinke U, Lower J (2006) TGN1412--a regulator's perspective. Nat Biotechnol 24(5): 493-496.

    • Schule S, Steidl S, Panitz S, Coulibaly C, Kalinke U, Cichutek K, Schweizer M (2006) Selective gene transfer to T lymphocytes using coreceptor-specific MLV(HIV) pseudotype vectors in a transgenic mouse model. Virology 351(1): 237-247.

    • Staib C, Suezer Y, Kisling S, Kalinke U, Sutter G (2006) Short-term, but not post-exposure, protection against lethal orthopoxvirus challenge after immunization with modified vaccinia virus Ankara. J Gen Virol 87(Pt 10): 2917-2921.

    2005

    • Dominguez D, Tournoy J, Hartmann D, Huth T, Cryns K, Deforce S, Serneels L, Camacho IE, Marjaux E, Craessaerts K, Roebroek AJ, Schwake M, D'Hooge R, Bach P, Kalinke U, Moechars D, Alzheimer C, Reiss K, Saftig P, De Strooper B (2005) Phenotypic and biochemical analyses of BACE1- and BACE2-deficient mice. J Biol Chem 280(35): 30797-30806.

    • Nikles D, Bach P, Boller K, Merten CA, Montrasio F, Heppner FL, Aguzzi A, Cichutek K, Kalinke U, Buchholz CJ (2005) Circumventing tolerance to the prion protein (PrP): vaccination with PrP-displaying retrovirus particles induces humoral immune responses against the native form of cellular PrP. J Virol 79(7): 4033-4042.

    • Strobl B, Bubic I, Bruns U, Steinborn R, Lajko R, Kolbe T, Karaghiosoff M, Kalinke U, Jonjic S, Muller M (2005) Novel functions of tyrosine kinase 2 in the antiviral defense against murine cytomegalovirus. J Immunol 175(6): 4000-4008.

    2004

    • Meier-Noorden M, Flindt S, Kalinke U, Hinz T (2004) A CpG-rich bidirectional promoter induces the T-cell death-associated gene 51 and downregulates an inversely oriented transcript during early T-cell activation. Gene 338(2): 197-207.

    2003

    • Hangartner L, Senn BM, Ledermann B, Kalinke U, Seiler P, Bucher E, Zellweger RM, Fink K, Odermatt B, Burki K, Zinkernagel RM, Hengartner H (2003) Antiviral immune responses in gene-targeted mice expressing the immunoglobulin heavy chain of virus-neutralizing antibodies.. Proc Natl Acad Sci U S A 100(22): 12883-12888.

    • Senn BM, Lopez-Macias C, Kalinke U, Lamarre A, Isibasi A, Zinkernagel RM, Hengartner H (2003) Combinatorial immunoglobulin light chain variability creates sufficient B cell diversity to mount protective antibody responses against pathogen infections.. Eur J Immunol 33(4): 950-961.

    2002

    • Barchet W, Cella M, Odermatt B, Asselin-Paturel C, Colonna M, Kalinke U (2002) Virus-induced interferon alpha production by a dendritic cell subset in the absence of feedback signaling in vivo.. J Exp Med 195(4): 507-516.

    • Scheu S, Alferink J, Potzel T, Barchet W, Kalinke U, Pfeffer K (2002) Targeted disruption of LIGHT causes defects in costimulatory T cell activation and reveals cooperation with lymphotoxin beta in mesenteric lymph node genesis.. J Exp Med 195(12): 1613-1624.

    2001

    • Heppner FL, Arrighi I, Kalinke U, Aguzzi A (2001) Immunity against prions?. Trends Mol Med 7(11): 477-479.

    • Heppner FL, Musahl C, Arrighi I, Klein MA, Rulicke T, Oesch B, Zinkernagel RM, Kalinke U, Aguzzi A (2001) Prevention of scrapie pathogenesis by transgenic expression of anti-prion protein antibodies. Science 294(5540): 178-182.

    • Klein MA, Kaeser PS, Schwarz P, Weyd H, Xenarios I, Zinkernagel RM, Carroll MC, Verbeek JS, Botto M, Walport MJ, Molina H, Kalinke U, Acha-Orbea H, Aguzzi A (2001) Complement facilitates early prion pathogenesis. Nat Med 7(4): 488-492.

    • Zinkernagel RM, LaMarre A, Ciurea A, Hunziker L, Ochsenbein AF, McCoy KD, Fehr T, Bachmann MF, Kalinke U, Hengartner H (2001) Neutralizing antiviral antibody responses. Adv Immunol n/a(79): 1-53.