Future Day 2026 at TWINCORE
Eleven pupils gain an insight into infection research
Infection research at the interface between clinical practice and basic research
TWINCORE was founded in 2008 by the Helmholtz Centre for Infection Research and the Hannover Medical School. We combine the expertise of medical professionals and scientists from a wide range of disciplines to find answers to the pressing questions in infection research. Our focus: translational research – the bridge between basic science and clinical application.
Lower Saxony International Summer Academy 2026
The LISA Summer School 2026 takes place from 23 August to 11 September 2026. Registration is open until 31 March.
Research
We conduct translational infection research to improve the prevention, diagnosis and treatment of infectious diseases in humans. We focus on three areas that characterize our research work. Find out here how we proceed and what results we achieve.
Labs at TWINCORE
Under the leadership of our best scientists, various labs are working on different projects within our research topics.
2026Aids (london, England) : 10.1097/QAD.0000000000004529
HIV immunological non-responders show low SKAP1 concentration and DNA hypermethylation in the SKAP1 promotor region: Low Skap1 in HIV Immunological Non-Responders
Vos W, De Ruijten S, Jiang X, van Unen N, van Snippenberg W, Groenendijk A, Blaauw M, Eekeren L, Vadaq N, Maas H, Östman M, Cleophas M, Brinkman K, van Lunzen J, Blok W, Stalenhoef J, Li Y, Netea M, Vandekerckhove L, Dos Santos J, Matzaraki V, Xu C, Ven A
2026Science Immunology11 (118) : eadw7077
Divergent granulopoiesis at extramedullary sites safeguards antibacterial host defense
Silvestre-Roig C, Chevre R, Farjia M, Bender A, Vöcking L, Richter M, Hageb A, Suerdieck V, Arenas Cerro F, Braster Q, Guzman M, Sintes J, Sharma S, Lemnitzer P, Tulotta C, Börgeling Y, Herrero-Cervera A, Flueter H, Reinartz Groba S, Ahern D, Osei-Sarpong C, Zimmer R, Alonso-Gonzalez N, Ortega E, Lienenklaus S, Kalinke U, Ludwig S, Engel D, Rosenbauer F, Monaco C, Dersch P, Kibler A, Cerutti A, Chavakis T, Benedito R, Hidalgo A, Jablonska J, Palomino-Segura M, Soehnlein O
2026Cell Genomics : 101218
Interferon-related inflammaging links epigenetic age acceleration to multimorbidity
Liu Z, Ziogas A, Zhang Y, Gupta M, Föhse K, Taks E, Dulfer E, Sarlea A, Ventriglia L, Geckin B, Ballan M, van Unen N, Helder L, Trittel S, Riese P, Moorlag S, de Bree C, Koeken V, Mourits V, Jaeger M, Pessler F, Guzmán C, Joosten L, Li Y, Xu C, Netea M
Kalinke Lab
Immunology
Regulation of acute hepatitis
The project investigates immune reactions in viral hepatitis, in particular the role of hepatocytes and myeloid cells. The aim is to understand immune processes in the liver and to develop diagnostic approaches for the clinic.
Pessler Lab
Immunology
Cerebrospinal fluid biomarkers for early diagnosis and risk stratification of CNS infections
In collaboration with the Department of Neurology and the Metabolomics Department, the project is investigating metabolic products in cerebrospinal fluid in order to identify biomarkers for CNS infections and cell damage and to distinguish long COVID and viral from autoimmune diseases.
Pietschmann Lab
Virology
Determinants of protective immunity in HCV: A gold standard for vaccine development
We are investigating how antibodies protect against HCV infection, in particular what properties they have during a healing infection. The aim is to identify antibodies that are important for an effective vaccine against HCV.
Behrendt Lab
Virology
Antiviral Strategies Against HEV
Together with the Department of Structural Biology at the University of Lübeck, human, strongly neutralizing antibodies against HEV were identified and characterized for the first time. These showed a protective effect in the mouse model and are currently being further developed for clinical application, including mRNA-based application methods.
Lecture Series - Regulatory Science and Translational Research - Part 5
"Interaction with regulators, e.g. in preparation of a first clinical study"
Seminar
TWINCORE Seminar
Dr. Verena Krähling
Institute of Virology
Medical Faculty
Marburg University
"Development of vaccine candidates against highly pathogenic viruses"
Seminar
TWINCORE Seminar
Prof. Dr. Andrea Maisner
Institute of Virology
Medical Faculty
Marburg University
"Unconventional plasma membrane clusters as assembly platforms for highly pathogenic Nipah virus: An imaging study"
Career at TWINCORE
Want to become part of TWINCORE?
Take a look at our job advertisements to see if there is something suitable for you or send us an unsolicited application.
