Diversity Day 2026 at TWINCORE
Diverse Origins - One Goal
Infection research at the interface between clinical practice and basic research
TWINCORE was founded in 2008 by the Helmholtz Centre for Infection Research and the Hannover Medical School. We combine the expertise of medical professionals and scientists from a wide range of disciplines to find answers to the pressing questions in infection research. Our focus: translational research – the bridge between basic science and clinical application.
Lower Saxony International Summer Academy 2026
The LISA Summer School 2026 takes place from 23 August to 11 September 2026. Registration is open until 31 March.
Research
We conduct translational infection research to improve the prevention, diagnosis and treatment of infectious diseases in humans. We focus on three areas that characterize our research work. Find out here how we proceed and what results we achieve.
Labs at TWINCORE
Under the leadership of our best scientists, various labs are working on different projects within our research topics.
2026Clinical Microbiology and Infection : The Official Publication of the European Society of Clinical Microbiology and Infectious Diseases : S1198-743X(26)00248-X
The role of whole genome sequencing in antimicrobial susceptibility prediction of bacteria: 2025 update from the EUCAST Subcommittee
Samuelsen Ø, López-Causapé C, Aarestrup F, Bortolaia V, Brouwer M, Cantón R, Egli A, Grad Y, Hamprecht A, Haussler S, Holt K, Hopkins K, Howden B, Jeannot K, Kahlmeter G, Köser C, Mathers A, Naas T, Pournaras S, Ruppé E, Schön T, Stoesser N, Turnidge J, Werner G, Wright G, Giske C, Oliver A
2026Science Advances12 (19) : eaeb5967
The pleuroparenchymal fibroelastosis atlas reveals aberrant cell states and their zonation as an alternate roadmap to lung fibrosis
Ruwisch J, Cazes A, Leiber L, Borie R, Neubert L, Christian L, Thomas de Montpréville V, Szmul A, Moussa F, Verleden S, Gaedcke S, Hegermann J, Fuge J, Ballmaier M, Kamp J, Greer M, Braubach P, Werlein C, Ius F, Graalmann T, Aburahma K, De Sadeleer L, Egashira R, Ackermann M, Yamada D, Hoeper M, Falk C, Gottlieb J, Schiller H, Vanaudenaerde B, Seeliger B, Debray M, Bernaudin J, Knudsen L, Bergot E, Jacob J, Mal H, Jonigk D, Dettmer S, Mordant P, Prasse A, Fadel E, Wuyts W, Crestani B, Kaminski N, Justet A, Schupp J
2026Journal of Virology : e0034226
Bile acids accumulate norovirus-like particles and enhance binding to and entry into human enteric epithelial cells
Hahlin E, Danskog K, Nord S, Becker M, Willekens S, Wibom C, Tanner H, Frängsmyr L, Öhlund D, Sandblad L, Lenman A, Arnberg N
Pessler Lab
Immunology
Cerebrospinal fluid biomarkers for early diagnosis and risk stratification of CNS infections
In collaboration with the Department of Neurology and the Metabolomics Department, the project is investigating metabolic products in cerebrospinal fluid in order to identify biomarkers for CNS infections and cell damage and to distinguish long COVID and viral from autoimmune diseases.
Pietschmann Lab
Virology
Mechanisms of HCV tissue and species tropism: A guide for development of animal models
The project investigates the factors that determine the species barrier mechanism of HCV and make it impossible to study the infection in animal models. The aim is to use genetic screening systems to develop in vivo models for vaccine research.
Pietschmann Lab
Virology
Host and viral factors that govern susceptibility to HCV and RSV
We are investigating why HCV infections sometimes heal spontaneously, but often become chronic, and why RSV infections are severe in some children. We use modern sequencing technologies to analyze the genetic characteristics of hosts and pathogens in order to understand susceptibility.
Behrendt Lab
Virology
Antiviral Strategies Against HEV
Together with the Department of Structural Biology at the University of Lübeck, human, strongly neutralizing antibodies against HEV were identified and characterized for the first time. These showed a protective effect in the mouse model and are currently being further developed for clinical application, including mRNA-based application methods.
Seminar
TWINCORE Seminar
Prof. Dr. Andrea Maisner
Institute of Virology
Medical Faculty
Marburg University
"Unconventional plasma membrane clusters as assembly platforms for highly pathogenic Nipah virus: An imaging study"
Lecture Series - Regulatory Science and Translational Research - Part 6
"Challenge Orphan medicines – learnings from the past"
Seminar
TWINCORE Seminar
Prof. John Schoggins
Soutwestern Medical Center
University of Texas
"Mechanisms and consequences of antiviral interferon-induced effectors"
Career at TWINCORE
Want to become part of TWINCORE?
Take a look at our job advertisements to see if there is something suitable for you or send us an unsolicited application.
