Diversity Day 2026 at TWINCORE
Diverse Origins – One Goal
Infection research at the interface between clinical practice and basic research
TWINCORE was founded in 2008 by the Helmholtz Centre for Infection Research and the Hannover Medical School. We combine the expertise of medical professionals and scientists from a wide range of disciplines to find answers to the pressing questions in infection research. Our focus: translational research – the bridge between basic science and clinical application.
Lower Saxony International Summer Academy 2026
The LISA Summer School 2026 takes place from 23 August to 11 September 2026. Registration is open until 31 March.
Research
We conduct translational infection research to improve the prevention, diagnosis and treatment of infectious diseases in humans. We focus on three areas that characterize our research work. Find out here how we proceed and what results we achieve.
Labs at TWINCORE
Under the leadership of our best scientists, various labs are working on different projects within our research topics.
2026Liver International : Official Journal of the International Association for the Study of the Liver46 (7) : e70727
Acute HEV Infection Is a Relevant Cause of Decompensation and ACLF in Patients With Liver Cirrhosis
Dinkelborg K, Niehaus C, Bremer B, Wundes C, Tiede A, Petruch N, Deterding K, Kraft A, Hartleben B, Cornberg M, Wedemeyer H, Behrendt P, Maasoumy B
2026Antibiotics (basel, Switzerland)15 (5) : 516
Multicenter Genomic Analysis of Carbapenem-Resistant Pseudomonas aeruginosa in Austrian Community Hospitals Reveals Limited Carbapenemase Prevalence and Absence of Interhospital Clonal Spread
Diab-Elschahawi M, Kirk T, Häussler S, Presterl E, The Psps Working Group
2026Clinical Microbiology and Infection : The Official Publication of the European Society of Clinical Microbiology and Infectious Diseases : S1198-743X(26)00248-X
The role of whole genome sequencing in antimicrobial susceptibility prediction of bacteria: 2025 update from the EUCAST Subcommittee
Samuelsen Ø, López-Causapé C, Aarestrup F, Bortolaia V, Brouwer M, Cantón R, Egli A, Grad Y, Hamprecht A, Haussler S, Holt K, Hopkins K, Howden B, Jeannot K, Kahlmeter G, Köser C, Mathers A, Naas T, Pournaras S, Ruppé E, Schön T, Stoesser N, Turnidge J, Werner G, Wright G, Giske C, Oliver A
Pietschmann Lab
Virology
Principles of HCV assembly and entry and their role in virus persistence
We are investigating how the association of HCV with lipoproteins contributes to the persistence of the virus by influencing entry into liver cells and protecting against antibodies. The aim is to gain new insights for the development of an HCV vaccine.
Behrendt Lab
Virology
Determinants of the Clinical Course of Infection
Human, potentially neutralizing antibodies against HEV have advanced the development of new detection methods for the virus in patient samples. Serological and functional analyses are used to determine markers for the course and treatment of chronic infections.
Galardini Lab
Bacteriology
Pangenome wide prediction of gene function
Thanks to high-throughput sequencing, genome sequences of hundreds of bacterial strains can be analyzed efficiently, revealing differences of up to 60 % in gene content, as in E. coli. With the help of machine learning, we want to better predict the functions of accessory genes and decipher their contribution to survival in specialized niches.
Kalinke Lab
Bartsch Lab
Behrendt Lab
Pietschmann Lab
Immunology
Platform for the rapid development of new pathogen-directed humanized or fully human monoclonal antibody candidates (MEMUMAB)
Monoclonal antibodies are transforming modern medicine. At Helmholtz Infection Medicine at MHH, bringing together TWINCORE and CiiM, advanced technologies and AI drive the development of next-generation human antibodies against major infectious diseases.
Seminar
TWINCORE Seminar
Prof. John Schoggins
Soutwestern Medical Center
University of Texas
"Mechanisms and consequences of antiviral interferon-induced effectors"
Seminar
TWINCORE Seminar
Prof. Dr. med. Axel Hamprecht
Institute of Medical Microbiology and Virology
Carl von Ossietzky Universität Oldenburg
"Carbapenemase-producing Enterobacterales - Molecular Characterization and Diagnostic Tools for the Early Detection of a Silent Epidemic"
Lecture Series - Regulatory Science and Translational Research - Part 1
"Why is knowledge in regulatory science important for translational medicine and basic science?"
Career at TWINCORE
Want to become part of TWINCORE?
Take a look at our job advertisements to see if there is something suitable for you or send us an unsolicited application.
