
Diversity Day 2026 at TWINCORE
Diverse Origins – One Goal

TWINCORE was founded in 2008 by the Helmholtz Centre for Infection Research and the Hannover Medical School. We combine the expertise of medical professionals and scientists from a wide range of disciplines to find answers to the pressing questions in infection research. Our focus: translational research – the bridge between basic science and clinical application.
The LISA Summer School 2026 takes place from 23 August to 11 September 2026. Registration is open until 31 March.
We conduct translational infection research to improve the prevention, diagnosis and treatment of infectious diseases in humans. We focus on three areas that characterize our research work. Find out here how we proceed and what results we achieve.
Under the leadership of our best scientists, various labs are working on different projects within our research topics.
Diab-Elschahawi M, Kirk T, Häussler S, Presterl E, The Psps Working Group
Samuelsen Ø, López-Causapé C, Aarestrup F, Bortolaia V, Brouwer M, Cantón R, Egli A, Grad Y, Hamprecht A, Haussler S, Holt K, Hopkins K, Howden B, Jeannot K, Kahlmeter G, Köser C, Mathers A, Naas T, Pournaras S, Ruppé E, Schön T, Stoesser N, Turnidge J, Werner G, Wright G, Giske C, Oliver A
Ruwisch J, Cazes A, Leiber L, Borie R, Neubert L, Christian L, Thomas de Montpréville V, Szmul A, Moussa F, Verleden S, Gaedcke S, Hegermann J, Fuge J, Ballmaier M, Kamp J, Greer M, Braubach P, Werlein C, Ius F, Graalmann T, Aburahma K, De Sadeleer L, Egashira R, Ackermann M, Yamada D, Hoeper M, Falk C, Gottlieb J, Schiller H, Vanaudenaerde B, Seeliger B, Debray M, Bernaudin J, Knudsen L, Bergot E, Jacob J, Mal H, Jonigk D, Dettmer S, Mordant P, Prasse A, Fadel E, Wuyts W, Crestani B, Kaminski N, Justet A, Schupp J
Together with the Department of Structural Biology at the University of Lübeck, human, strongly neutralizing antibodies against HEV were identified and characterized for the first time. These showed a protective effect in the mouse model and are currently being further developed for clinical application, including mRNA-based application methods.
Using high-performance computers, we analyze NGS data to discover unknown viruses in the human and animal virome that could influence disease risks. We investigate the virome as a factor for infections and diseases such as cancer and immunodeficiencies.
The CoViPa consortium uses computer-assisted high-throughput virus discovery and evolutionary analyses to identify RNA viruses with high spillover risk and potential animal host reservoirs and to investigate new pathogenicity factors.
Population genetic studies show that genetic variability between bacterial strains can influence the evolution of antimicrobial resistance. Using automated laboratory evolution (ALE), we are investigating how genetic backgrounds control AMR evolution.
"Challenge Orphan medicines – learnings from the past"
Prof. John Schoggins
Soutwestern Medical Center
University of Texas
"Mechanisms and consequences of antiviral interferon-induced effectors"
Prof. Dr. med. Axel Hamprecht
Institute of Medical Microbiology and Virology
Carl von Ossietzky Universität Oldenburg
"Carbapenemase-producing Enterobacterales - Molecular Characterization and Diagnostic Tools for the Early Detection of a Silent Epidemic"

