Future Day 2026 at TWINCORE
Eleven pupils gain an insight into infection research
Infection research at the interface between clinical practice and basic research
TWINCORE was founded in 2008 by the Helmholtz Centre for Infection Research and the Hannover Medical School. We combine the expertise of medical professionals and scientists from a wide range of disciplines to find answers to the pressing questions in infection research. Our focus: translational research – the bridge between basic science and clinical application.
Lower Saxony International Summer Academy 2026
The LISA Summer School 2026 takes place from 23 August to 11 September 2026. Registration is open until 31 March.
Research
We conduct translational infection research to improve the prevention, diagnosis and treatment of infectious diseases in humans. We focus on three areas that characterize our research work. Find out here how we proceed and what results we achieve.
Labs at TWINCORE
Under the leadership of our best scientists, various labs are working on different projects within our research topics.
2026Journal of Virology : e0034226
Bile acids accumulate norovirus-like particles and enhance binding to and entry into human enteric epithelial cells
Hahlin E, Danskog K, Nord S, Becker M, Willekens S, Wibom C, Tanner H, Frängsmyr L, Öhlund D, Sandblad L, Lenman A, Arnberg N
2026Aids (london, England) : 10.1097/QAD.0000000000004529
HIV immunological non-responders show low SKAP1 concentration and DNA hypermethylation in the SKAP1 promotor region: Low Skap1 in HIV Immunological Non-Responders
Vos W, De Ruijten S, Jiang X, van Unen N, van Snippenberg W, Groenendijk A, Blaauw M, Eekeren L, Vadaq N, Maas H, Östman M, Cleophas M, Brinkman K, van Lunzen J, Blok W, Stalenhoef J, Li Y, Netea M, Vandekerckhove L, Dos Santos J, Matzaraki V, Xu C, Ven A
2026Science Immunology11 (118) : eadw7077
Divergent granulopoiesis at extramedullary sites safeguards antibacterial host defense
Silvestre-Roig C, Chevre R, Farjia M, Bender A, Vöcking L, Richter M, Hageb A, Suerdieck V, Arenas Cerro F, Braster Q, Guzman M, Sintes J, Sharma S, Lemnitzer P, Tulotta C, Börgeling Y, Herrero-Cervera A, Flueter H, Reinartz Groba S, Ahern D, Osei-Sarpong C, Zimmer R, Alonso-Gonzalez N, Ortega E, Lienenklaus S, Kalinke U, Ludwig S, Engel D, Rosenbauer F, Monaco C, Dersch P, Kibler A, Cerutti A, Chavakis T, Benedito R, Hidalgo A, Jablonska J, Palomino-Segura M, Soehnlein O
Kalinke Lab
Immunology
Cell-selective delivery of active compounds
The project is developing methods to specifically transport antibiotics into cells such as alveolar macrophages, which are important in Mycobacterium tuberculosis infections. The aim is to overcome resistance and reduce side effects.
Pietschmann Lab
Virology
Principles of HCV assembly and entry and their role in virus persistence
We are investigating how the association of HCV with lipoproteins contributes to the persistence of the virus by influencing entry into liver cells and protecting against antibodies. The aim is to gain new insights for the development of an HCV vaccine.
Lauber Lab
Virology
Genetic determinants of severe RSV infection in infants
We are investigating how genetic variants influence the risk of severe RSV infections in infants. Exome sequencing and bioinformatic analyses are used to identify causal variants in immunity genes.
Kalinke Lab
Bartsch Lab
Behrendt Lab
Pietschmann Lab
Immunology
Platform for the rapid development of new pathogen-directed humanized or fully human monoclonal antibody candidates (MEMUMAB)
Monoclonal antibodies are transforming modern medicine. At Helmholtz Infection Medicine at MHH, bringing together TWINCORE and CiiM, advanced technologies and AI drive the development of next-generation human antibodies against major infectious diseases.
Lecture Series - Regulatory Science and Translational Research - Part 5
"Interaction with regulators, e.g. in preparation of a first clinical study"
Seminar
TWINCORE Seminar
Dr. Verena Krähling
Institute of Virology
Medical Faculty
Marburg University
"Development of vaccine candidates against highly pathogenic viruses"
Seminar
TWINCORE Seminar
Prof. Dr. Andrea Maisner
Institute of Virology
Medical Faculty
Marburg University
"Unconventional plasma membrane clusters as assembly platforms for highly pathogenic Nipah virus: An imaging study"
Career at TWINCORE
Want to become part of TWINCORE?
Take a look at our job advertisements to see if there is something suitable for you or send us an unsolicited application.
