We perform translational infection research to improve prevention, diagnosis and treatment of human infectious diseases. Our multidisziplinary research teams integreate clinical and basic researchers. Together, we strive to channel knowledge arising from basic research into clinical practice, and also to translate clinical observations into an improved understanding of disease mechanisms.
At TWINCORE currently around 160 people are working on the question: What happens during an infection and what can we do against it? Physicians, virologists, bacteriologists and immunologists at TWINCORE research in four areas:
Our researchers are investigating in interdisciplinary teams how pathogens and host cells interact with each other and how this interaction can be inhibited. They are working on new vaccine strategies that train the immune system more targeted than previous vaccination practices were able to. And to safely investigate such serious diseases as hepatitis C our scientists develop new preclinical model systems - from new cell culture systems to mice whose immune systems are the most similar to humans.