Season's Greetings
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Infection research at the interface between clinical practice and basic research
TWINCORE was founded in 2008 by the Helmholtz Centre for Infection Research and the Hannover Medical School. We combine the expertise of medical professionals and scientists from a wide range of disciplines to find answers to the pressing questions in infection research. Our focus: translational research – the bridge between basic science and clinical application.
Research
We conduct translational infection research to improve the prevention, diagnosis and treatment of infectious diseases in humans. We focus on three areas that characterize our research work. Find out here how we proceed and what results we achieve.
Labs at TWINCORE
Under the leadership of our best scientists, various labs are working on different projects within our research topics.
2025Bmc Infectious Diseases : 10.1186/s12879-025-12211-8
Guidelines on reporting and assessing dynamic mathematical models of infectious diseases: a scoping review
Chaturvedi M, Bartz A, Denkinger C, Klett-Tammen C, Kretzschmar M, Kuhlmann A, Lange B, Marx F, Mikolajczyk R, Monsef I, Nguyen H, Suer J, Skoetz N, Jaeger V, Karch A
2025The Journal of Infectious Diseases : jiaf654
Transient interferon-driven NK cell activation in acute hepatitis C
Strunz B, Zhan Q, Khera T, Hengst J, Jankovic M, Deterding K, Niehrs A, Cornberg M, Xu C, Wedemeyer H, Björkström N
2025Plos One20 (12) : e0337890
Dynamic growth risk of incidentally detected gallbladder polyps-A retrospective, single-center analysis
Heinrich S, Ten Thoren P, Behrendt P, Hagenah J, Wedemeyer H, Potthoff A, Maasoumy B
Kalinke Lab
Immunology
Cell-selective delivery of active compounds
The project is developing methods to specifically transport antibiotics into cells such as alveolar macrophages, which are important in Mycobacterium tuberculosis infections. The aim is to overcome resistance and reduce side effects.
Pessler Lab
Immunology
Functional Biomarkers for respiratory infections
This project focuses on lung infections such as influenza, COVID-19, pneumonia and tuberculosis in order to improve diagnostics, patient stratification and therapy. RNA molecules and metabolites are being investigated as biomarkers and complementary therapies.
Pietschmann Lab
Virology
Antiviral agents against HCV, RSV and coronavirus
We develop high-throughput screening assays to identify antiviral molecules against RSV and SARS-CoV-2. We use compound libraries, investigate new mechanisms of action and strive for innovative therapies.
Galardini Lab
Bacteriology
Testing the impact of genetic backgrounds on antimicrobial resistance
Population genetic studies show that genetic variability between bacterial strains can influence the evolution of antimicrobial resistance. Using automated laboratory evolution (ALE), we are investigating how genetic backgrounds control AMR evolution.
There are currently no events.
Career at TWINCORE
Want to become part of TWINCORE?
Take a look at our job advertisements to see if there is something suitable for you or send us an unsolicited application.
