Mittwoch 19. September 2018

TWINCORE-Seminar

Jun. Prof. Dr. Neva Caliskan

Helmholtz Institute for RNA-based Infection Research Würzburg

Titel: Exploring the hidden code of the genomes during infections

Zeit: 16:00 Uhr s.t.,
Ort: TWINCORE Seminar room 0.02

Ansprechpartner: Prof. Thomas Pietschmann

Research profile

Recoding defines the non-standard decoding of specific mRNAs, which is stimulated by cis- and trans- acting elements. The central focus of our lab is to identify molecular players of translational recoding events in viral pathogens and eukaryotic host cells. We aim to discover novel unconventional translation events in emerging RNA viruses and cellular genes to understand the mechanistic details as well as to characterize the RNA-interactome of pathogens and host cells, which can be of crucial importance in pathogenic processes and cellular responses. To this end, we are using a highly interdisciplinary approach that combines cutting-edge RNA analytics, such as ribosome profiling and deep sequencing, with biochemical and computational tools.