Establishment of a cohort for deep phenotyping of the immune response to influenza vaccination among elderly individuals recruited from the general population

Manas Akmatov

Key message

We describe the conduct of a study about influenza vaccination among elderly individuals, the collected biosamples, as well as the planned analyses. The study participants were highly motivated leading to a complete data- and biomaterialset.

Translational perspective

The primary aim of the study is to identify biomarkers (molecules in blood) that can predict a poor response to influenza vaccination even before vaccination.  This will help to develop a highly efficacious vaccine.