Clinical translational research

Clinical background
Infection medicine presents a variety of challenges and medical needs. Infections with multi-resistant bacteria constitute a particularly threat. Furthermore,viral infections can often not be treated effectively. At the same time, the number of patients with increased infection susceptibility is increasing. Such patients include newborns and elderly indivuals, who have an immature or senescent immune system, respectively. Additionally, innovative therapies such as transplantation and treatment with immunosuppressive drugs are used more broadly, which also enhances the proportion of susceptible individuals.
TWINCORE strategy
At TWINCORE we develop research projects on the basis of clinical observations and clinical challenges. We focus on the analysis of infections of the gastrointestinal tract, the liver, the lung, and the central nervous system. We pay particular attention to the analysis of patients with enhanced vulnerability to infectious disease, such as newborns and the elderly. We carry out research in multidisciplinary teams which often include the clinicians treating the patients.