Selected publications
Winstel V, Abt ER, Le TM, Radu CG (2024) Targeting host deoxycytidine kinase mitigates Staphylococcus aureus abscess formation. Elife 12
Schwermann N, Haller R, Koch S, Grassl GA, Winstel V (2023) Pathogen-driven nucleotide overload triggers mitochondria-centered cell death in phagocytes. PLoS Pathog 19(12): e1011892.
Schwermann N, Winstel V (2023) Functional diversity of staphylococcal surface proteins at the host-microbe interface. Front Microbiol 14: 1196957. Review
Tantawy E, Schwermann N, Ostermeier T, Garbe A, Bahre H, Vital M, Winstel V (2022) Staphylococcus aureus Multiplexes Death-Effector Deoxyribonucleosides to Neutralize Phagocytes. Front Immunol 13: 847171.
von Kockritz-Blickwede M, Winstel V (2022) Molecular Prerequisites for Neutrophil Extracellular Trap Formation and Evasion Mechanisms of Staphylococcus aureus. Front Immunol 13: 836278.
Du X, Larsen J, Li M, Walter A, Slavetinsky C, Both A, Sanchez Carballo PM, Stegger M, Lehmann E, Liu Y, Liu J, Slavetinsky J, Duda KA, Krismer B, Heilbronner S, Weidenmaier C, Mayer C, Rohde H, Winstel V, Peschel A (2021) Staphylococcus epidermidis clones express Staphylococcus aureus-type wall teichoic acid to shift from a commensal to pathogen lifestyle. Nat Microbiol 6(6): 757-768.
Fisarova L, Botka T, Du X, Maslanova I, Bardy P, Pantucek R, Benesik M, Roudnicky P, Winstel V, Larsen J, Rosenstein R, Peschel A, Doskar J (2021) Staphylococcus epidermidis Phages Transduce Antimicrobial Resistance Plasmids and Mobilize Chromosomal Islands. mSphere 6(3).
Bunsow D, Tantawy E, Ostermeier T, Bahre H, Garbe A, Larsen J, Winstel V (2021) Methicillin-resistant Staphylococcus pseudintermedius synthesizes deoxyadenosine to cause persistent infection. Virulence 12(1): 989-1002.
Missiakas D, Winstel V (2021) Selective Host Cell Death by Staphylococcus aureus: A Strategy for Bacterial Persistence. Front Immunol 11: 621733.
Winstel V, Schneewind O, Missiakas D (2019) Staphylococcus aureus exploits the host apoptotic pathway to persist during infection. MBio 10(6)
Winstel V, Missiakas D, Schneewind O (2018) Staphylococcus aureus targets the purine salvage pathway to kill phagocytes. Proc Natl Acad Sci U S A 115(26): 6846-6851.
Wanner S, Schade J, Keinhorster D, Weller N, George SE, Kull L, Bauer J, Grau T, Winstel V, Stoy H, Kretschmer D, Kolata J, Wolz C, Broker BM, Weidenmaier C (2017) Wall teichoic acids mediate increased virulence in Staphylococcus aureus. Nat Microbiol 2: 16257.
Winstel V, Kuhner P, Rohde H, Peschel A (2016) Genetic engineering of untransformable coagulase-negative staphylococcal pathogens. Nat Protoc 11(5): 949-959.
Li X, Gerlach D, Du X, Larsen J, Stegger M, Kuhner P, Peschel A, Xia G, Winstel V (2015) An accessory wall teichoic acid glycosyltransferase protects Staphylococcus aureus from the lytic activity of Podoviridae. Sci Rep 5: 17219.
Winstel V, Kuhner P, Salomon F, Larsen J, Skov R, Hoffmann W, Peschel A, Weidenmaier C (2015) Wall Teichoic Acid Glycosylation Governs Staphylococcus aureus Nasal Colonization. MBio 6(4): e00632.
Winstel V, Kuhner P, Krismer B, Peschel A, Rohde H (2015) Transfer of plasmid DNA to clinical coagulase-negative staphylococcal pathogens by using a unique bacteriophage. Appl Environ Microbiol 81(7): 2481-2488.
Winstel V, Sanchez-Carballo P, Holst O, Xia G, Peschel A (2014) Biosynthesis of the unique wall teichoic acid of Staphylococcus aureus lineage ST395. MBio 5(2): e00869.
Winstel V, Liang C, Sanchez-Carballo P, Steglich M, Munar M, Broker BM, Penades JR, Nubel U, Holst O, Dandekar T, Peschel A, Xia G (2013) Wall teichoic acid structure governs horizontal gene transfer between major bacterial pathogens. Nat Commun 4: 2345.
Brown S, Xia G, Luhachack LG, Campbell J, Meredith TC, Chen C, Winstel V, Gekeler C, Irazoqui JE, Peschel A, Walker S (2012) Methicillin resistance in Staphylococcus aureus requires glycosylated wall teichoic acids. Proc Natl Acad Sci U S A 109(46): 18909-18914.