Publications

Schlevogt B, Kinast V, Reusch J, Kerkhoff A, Praditya D, Todt D, Schmidt HH, Steinmann E, Behrendt P (2019) Chronic Hepatitis E Virus Infection during Lymphoplasmacytic Lymphoma and Ibrutinib Treatment. Pathogens 8(3).

Soon CF, Behrendt P, Todt D, Manns MP, Wedemeyer H, Chen MS, Cornberg M (2019) Defining virus-specific CD8+ TCR repertoires for therapeutic regeneration of T cells against chronic hepatitis E. J Hepatol 71(4): 673-684.

Khera T*, Behrendt P*, Bankwitz D, Brown RJP, Todt D, Doepke M, Khan AG, Schulze K, Law J, Logan M, Hockman D, Wong JAJ-X, Dold L, Gonzalez-Motos V, Spengler U, Viejo-Borbolla A, Ströh L, Krey T, Tarr AW, Steinmann E, Manns MP, Klein F, Guzman CA, Marcotrigiano J, Houghton M, Pietschmann T (2019) Functional and immunogenic characterization of diverse HCV glycoprotein E2 variants. J Hepatol 70(4): 593-602. *shared first

Behrendt P, Bruning J, Todt D, Steinmann E (2019) Influence of Tattoo Ink on Hepatitis C Virus Infectiousness. Open Forum Infect Dis 6(3): ofz047.

Beer A, Holzmann H, Pischke S, Behrendt P, Wrba F, Schlue J, Drebber U, Neudert B, Halilbasic E, Kreipe H, Lohse A, Sterneck M, Wedemeyer H, Manns M, Dienes HP (2019) Chronic Hepatitis E is associated with cholangitis. Liver Int 39(10): 1876-1883.

Todt D, Moeller N, Praditya D, Kinast V, Friesland M, Engelmann M, Verhoye L, Sayed IM, Behrendt P, Thi VLD, Meuleman Philip, Steinmann Eike (2018) The natural compound silvestrol inhibits hepatitis E virus (HEV) replication in vitro and in vivo. Antiviral Res 157: 151-158.

Pfaender S, Helfritz FA, Siddharta A, Todt D, Behrendt P, Heyden J, Riebesehl N, Willmann W, Steinmann J, Münch J, Ciesek S, Steinmann E (2018) Environmental Stability and Infectivity of Hepatitis C Virus (HCV) in Different Human Body Fluids. Front Microbiol 9: 504.

Knegendorf L, Drave SA, Dao Thi VL, Debing Y, Brown RJP, Vondran FWR, Resner K, Friesland M, Khera T, Engelmann M, Bremer B, Wedemeyer H., Behrendt P, Neyts J, Pietschmann T, Todt D, Steinmann E (2018) Hepatitis E virus replication and interferon responses in human placental cells. Hepatol Commun 2(2): 173-187.

Al-Ayoubi J, Behrendt P, Bremer B, Suneetha PV, Gisa A, Rinker F, Manns MP, Cornberg M, Wedemeyer H, Kraft ARM (2018) Hepatitis E virus ORF 1 induces proliferative and functional T-cell responses in patients with ongoing and resolved hepatitis E. Liver Int 38(2): 266-277.

Behrendt P*, Perin P*, Menzel N, Banda D, Pfaender S, Alves MP, Thiel V, Meulemann P, Colpitts CC, Schang LM, Vondran FWR, Anggakusuma, Manns MP, Steinmann E, Pietschmann T (2017) Pentagalloylglucose, a highly bioavailable polyphenolic compound present in Cortex moutan, efficiently blocks hepatitis C virus entry. Antiviral Res 147: 19-28.  *shared first

Behrendt P, Lüth S, Dammermann W, Drave S, Brown RJP, Todt D, Schnoor U, Steinmann E, Wedemeyer H, Pischke S, Iking-Konert C (2017) Exacerbation of hepatitis E virus infection during anti-TNFα treatment. Joint Bone Spine 84(2): 217-219.

Bankwitz D, Doepke M, Hueging K, Weller R, Bruening J, Behrendt P, Lee JY, Vondran FWR, Manns MP, Bartenschlager R, Pietschmann T (2017) Maturation of secreted HCV particles by incorporation of secreted apoE protects from antibodies by enhancing infectivity. J Hepatol 67(3): 480-489.

Todt D, Gisa A, Radonic A, Nitsche A, Behrendt P, Suneetha PV, Pischke S, Bremer B, Brown RJP, Manns MP, Cornberg M, Bock CT, Steinmann E, Wedemeyer H (2016) In vivo evidence for ribavirin-induced mutagenesis of the hepatitis E virus genome. Gut 65(10): 1733-1743.

Todt D., Francois C., Anggakusuma, Behrendt P, Engelmann M, Knegendorf L, Vieyres G, Wedemeyer H, Hartmann R, Pietschmann T, Duverlie G, Steinmann E (2016) Antiviral activity of different interferon (sub-) types against hepatitis E virus replication. Antimicrob Agents Chem 60(4): 2132-2139.

Pischke S, Bara C, Behrendt P, Haverich A, Manns MP, Wedemeyer H (2016) Low Risk of Developing Chronic Hepatitis E in Heart Transplant Recipients: A Prospective 2-Year Follow-Up Study. Intervirology 59(5-6): 254-255.

Gisa A, Suneetha PV, Behrendt P, Pischke S, Bremer B, Falk CS, Manns MP, Cornberg M, Wedemeyer H, Kraft AR (2016) Cross-genotype-specific T-cell responses in acute hepatitis E virus (HEV) infection. J Viral Hepat 23(4): 305-315.

Drave SA, Debing Y, Walter S, Todt D, Engelmann M, Friesland M, Wedemeyer H, Neyts J, Behrendt P, Steinmann E (2016) Extra-hepatic replication and infection of hepatitis E virus in neuronal-derived cells. J Viral Hep 23(7): 512-521.

Behrendt P, Bremer B, Todt D, Brown RJP, Heim A, Manns MP, Steinmann E, Wedemeyer H (2016) Hepatitis E Virus (HEV) ORF2 Antigen Levels Differentiate Between Acute and Chronic HEV Infection. J Infect Dis 214(3): 361-368.

Abd-Elshafy DN, Pietschmann T, Muller-Ladner U, Neumann E, Anggakusuma, M BahgatM, Pessler F, Behrendt P (2015) Cell culture-derived HCV cannot infect synovial fibroblasts. Sci Rep 5 18043.

Pischke S, Schwarze-Zander C, Bremer B, Lehmann P, Wiegand SB, Gisa A, Behrendt P, Strassburg CP, Manns MP, Wedemeyer H, Rockstroh JK (2015) Hepatitis E Virus Seroprevalence Rate in HIV-Infected Patients in Germany: A Comparison of Two Commercial Assays. Intervirology 58(5): 283-287.

Pfaender S, Walter S, Todt D, Behrendt P, Doerrbecker J, Woelk B, Engelmann M, Gravemann U, Seltsam A, Steinmann J, Burbelo PD, Klawonn F, Feige K, Pietschmann T, Cavalleri JM, Steinmann E (2015) Assessment of cross-species transmission of hepatitis C-related non-primate hepacivirus in a population of humans at high risk of exposure. J Gen Virol 96(9): 2636-2642. 

Hedenstierna M, Weiland O, Brass A, Bankwitz D, Behrendt P, Uhnoo I, Aleman S, Cardell K, Fryden A, Norkrans G, Eilard A, Glaumann H, Pietschmann T, Sallberg M, Brenndorfer ED (2015) Long-term follow-up of successful hepatitis C virus therapy: waning immune responses and disappearance of liver disease are consistent with cure. Aliment Pharmacol Ther 41(6): 532-543.

Anggakusuma, Romero-Brey I, Berger C, Colpitts CC, Boldanova T, Engelmann M, Todt D, Perin PM, Behrendt P, Vondran FW, Xu S, Goffinet C, Schang LM, Heim MH, Bartenschlager R, Pietschmann T, Steinmann E (2015) Interferon-inducible cholesterol-25-hydroxylase restricts hepatitis C virus replication via blockage of membranous web formation. Hepatology 62(3): 702-714.

Pischke S, Behrendt P, Manns MP, Wedemeyer H (2014) HEV-associated cryoglobulinaemia and extrahepatic manifestations of hepatitis E. Lancet Infect Dis 14(8): 678-679.

Pischke S, Behrendt P, Bock CT, Jilg W, Manns MP, Wedemeyer H (2014) Hepatitis E in Germany--an under-reported infectious disease. Dtsch Arztebl Int 111(35-36): 577-583.

Doerrbecker J, Friesland M, Riebesehl N, Ginkel C, Behrendt P, Brown RJ, Ciesek S, Wedemeyer H, Sarrazin C, Kaderali L, Pietschmann T, Steinmann E (2014) Incorporation of primary patient-derived glycoproteins into authentic infectious hepatitis C virus particles. Hepatology 60(2): 508-520.

Behrendt P, Steinmann E, Manns MP, Wedemeyer H (2014) The impact of hepatitis E in the liver transplant setting. J Hepatol 61(6): 1418-1429.

Anggakusuma, Colpitts CC, Schang LM, Rachmawati H, Frentzen A, Pfaender S, Behrendt P, Brown RJ, Bankwitz D, Steinmann J, Ott M, Meuleman P, Rice CM, Ploss A, Pietschmann T, Steinmann E (2014) Turmeric curcumin inhibits entry of all hepatitis C virus genotypes into human liver cells. Gut 63(7): 1137-1149.

Doerrbecker J, Behrendt P, Mateu-Gelabert P, Ciesek S, Riebesehl N, Wilhelm C, Steinmann J, Pietschmann T, Steinmann E (2013) Transmission of Hepatitis C virus among people who inject drugs: viral stability and association with drug preparation equipment. J Infect Dis 207(2): 281-287.

Behrendt P, Doerrbecker J, Riebesehl N, Wilhelm C, Ciesek S, Erichsen TJ, Steinmann J, Ott M, Manns MP, Pietschmann T, Steinmann E (2013) Stability and transmission of hepatitis C virus in different anesthetic agents. Am J Infect Control 41(10): 942-943.

Behrendt P, Buchenauer T, Horn R, Brabant G, Jacobs R, Bode F, Stephan M, Nave H (2010) Diet-induced obesity, exogenous leptin-, and MADB106 tumor cell challenge affect tissue leukocyte distribution and serum levels of cytokines in F344 rats. Endocrine 38(1): 104-112.

Buchenauer T, Behrendt P, Bode FJ, Horn R, Brabant G, Stephan M, Nave H (2009) Diet-induced obesity alters behavior as well as serum levels of corticosterone in F344 rats. Physiol Behav 98(5): 563-569.

Nave H, Mueller G, Siegmund B, Jacobs R, Stroh T, Schueler U, Hopfe M, Behrendt P, Buchenauer T, Pabst R, Brabant G (2008) Resistance of Janus kinase-2 dependent leptin signaling in natural killer (NK) cells: a novel mechanism of NK cell dysfunction in diet-induced obesity. Endocrinology 149(7): 3370-3378.