Research Group Virus Transmission

Research Group Virus Transmission

HCV, a plus strand RNA virus has chronically infected ca. 71 mio individuals and a vaccine is not available. In fact, chronic HCV infection is associated with about 30% of liver cancers worldwide and among the leading indications for orthotopic liver transplantation. Another RNA virus is hepatitis E virus (HEV) which is responsible for epidemics and endemics of acute hepatitis mainly through waterborne, foodborne, and zoonotic transmission routes. The research group “Virus Transmission” of Prof. Eike Steinmann is working on molecular and clinical transmission pathways of hepatitis C virus (HCV) and hepatitis E virus (HEV) causing severe infections in humans. Therefore, new prevention strategies and therapies for these two RNA viruses should be developed. Risks of virus transmission in the environment, especially in the hospital should be identified as well as effective methods for virus inactivation established and validated. Another focus is to investigate the relevance and utility of HCV-related viruses in horses as model for HCV transmission and pathogenesis. The so-called non-primate hepacivirus (NPHV) is the closest relative of HCV described to date und opens new opportunities to study the natural infection of NPHV in its host.

News

17. May 2018

Doctoral awards of the HZI and MHH for Daniel Todt

Daniel Todt, scientist at the Research Group Virus Transmission at the Institute for Experimental Virology, received the Doctoral award of the Hannover Medical School for his research on the hepatitis E virus on May 8, 2018....


09. February 2018

New treatment approach for hepatitis E infections in pregnant women

Hepatitis E virus infections are usually subclinical and are considered as an underrated disease by physicians. The number of infections worldwide is estimated at 20 million infected people per year. In our latitudes, primarily...


09. March 2017

New perspectives for research on hepatitis C virus

The hepatitis C virus (HCV) infects around 160 million people worldwide. Although there are new therapies, HCV infection is still one of the most common causes of liver transplantation as these new drugs are very expensive and...


13. February 2017

WHO handrub formulations are effective against emerging viruses

In the last few years, previously unknown viruses or viruses, which were considered eliminated, have been unveiled: last year, the World Health Organization WHO declared “A Public Health Emergency of International Concern”...


28. November 2016

Hepatitis C and HIV prophylaxis from the microwave – A powerful kitchen tool reduces viral transmission in the drug injection community

Infections with hepatitis C virus (HCV) and human immunodeficiency virus (HIV) among people who inject drugs (PWID) are a global health problem. For example, sharing of drug preparation equipment within this population...