Publikationen

2011

Berod, L.; Heinemann, C.; Heink, S.; Escher, A.; Stadelmann, C.; Drube, S.; Wetzker, R.; Norgauer, J. & Kamradt, T. (2011), 'PI3K? deficiency delays the onset of experimental autoimmune encephalomyelitis and ameliorates its clinical outcome.', Eur J Immunol 3 2011 Jan 04 [Epub ahead of print] n/a , n/a .
[Kurzfassung]   [BibTeX]  [Endnote] 

Dietze, K.; Zelinskyy, G.; Gibbert, K.; Schimmer, S.; Francois, S.; Myers, L.; Sparwasser, T.; Hasenkrug, K. & Dittmer, U. (2011), 'Transient depletion of regulatory T cells in transgenic mice reactivates virus-specific CD8+ T cells and reduces chronic retroviral set points', Proc Nate Acad Sci Jan 24, 10151481083 [Epub ahead of print] (108(6)) .
[Kurzfassung]   [BibTeX]  [Endnote] 

Vaeth, M.; Gogishvili, T.; Bopp, T.; Klein, M.; Berberich-Siebelt, F.; Gattenloehner, S.; Avots, A.; Sparwasser, T.; Grebe, N.; Schmitt, E.; Hunig, T.; Serfling, E. & Bodor, J. (2011), 'Regulatory T cells facilitate the nuclear accumulation of inducible cAMP early repressor (ICER) and suppress nuclear factor of activated T cell c1 (NFATc1)', Proc Natl Acad Sci U S A 3 [Epub ahead of print] (108(6)) .
[Kurzfassung]   [BibTeX]  [Endnote] 

Pellegrini, M.; Calzascia, T.; Toe, J.; Preston, S.; Lin, A.; Elford, A.; Shahinian, A.; Lang, P.; Lang, K.; Morre, M.; Assouline, B.; Lahl, K.; Sparwasser, T.; Tedder, T.; Paik, J.; DePinho, R.; Basta, S.; Ohashi, P. & Mak, T. (2011), 'IL-7 engages multiple mechanisms to overcome chronic viral infection and limit organ pathology', Cell [Epub ahead of print] (144(4)) .
[Kurzfassung]   [BibTeX]  [Endnote] 

Blankenhaus, B.; Klemm, U.; Eschbach, M. L.; Sparwasser, T.; Huehn, J.; Kühl, A. A.; Loddenkemper, C.; Jacobs, T. & Breloer, M. (2011), 'Strongyloides ratti Infection Induces Expansion of Foxp3+ Regulatory T Cells That Interfere with Immune Response and Parasite Clearance in BALB/c Mice', J Immunol (186(7)) .
[Kurzfassung]   [BibTeX]  [Endnote] 

Lochner, M.; Ohnmacht, C.; Presley, L.; Bruhns, P.; Si-Tahar, M.; Sawa, S. & Eberl, G. (2011), 'Microbiota-induced tertiary lymphoid tissues aggravate inflammatory disease in the absence of RORgt and LTi cells', J Exp Med 208 (208(1)) , 125-134 .
[Kurzfassung]   [BibTeX]  [Endnote] 

Pellegrini, M.; Calzascia, T.; Toe, J.; Preston, S.; Lin, A.; Elford, A.; Shahinian, A.; Lang, P.; Lang, K.; Morre, M.; Assouline, B.; Lahl, K.; Sparwasser, T.; Tedder, T.; Paik, J.; DePinho, R.; Basta, S.; Ohashi, P. & Mak, T. (2011), 'IL-7 engages multiple mechanisms to overcome chronic viral infection and limit organ pathology.', Cell 144 (4) , 601-613 .
[Kurzfassung]   [BibTeX]  [Endnote] 

Stagg, J.; Divisekera, U.; Duret, H.; Sparwasser, T.; Teng, M.; Darcy, P. & Smyth, M. (2011), 'CD73-deficient mice have increased antitumor immunity and are resistant to experimental metastasis.', Cancer Res 71 (8) , 2892-2900 .
[Kurzfassung]   [BibTeX]  [Endnote] 

Hadis, U.; Wahl, B.; Schulz, O.; Hardtke-Wolenski, M.; Schippers, A.; Wagner, N.; Muller, W.; Sparwasser, T.; Forster, R. & Pabst, O. (2011), 'Intestinal tolerance requires gut homing and expansion of FoxP3+ regulatory T cells in the lamina propria.', Immunity 34 (2) , 237-246 .
[Kurzfassung]   [BibTeX]  [Endnote] 

Ohnmacht, C.; Marques, R.; Presley, L.; Sawa, S.; Lochner, M. & Eberl, G. (2011), 'Intestinal microbiota, evolution of the immune system and the bad reputation of proinflammatory immunity.', Cell Microbiol 13 (5) , 653-659 .
[BibTeX]  [Endnote] 

Sawa, S.; Lochner, M.; Satoh-Takayama, N.; S, D.; Berard, M.; Kleinschek, M.; Cua, D.; Di Santo, J. & Eberl, G. (2011), 'RORgammat+ innate lymphoid cells regulate intestinal homeostasis by integrating negative signals from the symbiotic microbiota.', Nat Immunol 12 (4) , 320-326 .
[Kurzfassung]   [BibTeX]  [Endnote] 

Blankenhaus, B.; Klemm, U.; Eschbach, M.; Sparwasser, T.; Huehn, J.; Kuhl, A.; Loddenkemper, C.; Jacobs, T. & Breloer, M. (2011), 'Strongyloides ratti infection induces expansion of Foxp3+ regulatory T cells that interfere with immune response and parasite clearance in BALB/c mice.', J Immunol 186 (7) , 4295-4305 .
[Kurzfassung]   [BibTeX]  [Endnote] 

Paust, H.; Ostmann, A.; Erhardt, A.; Turner, J.; Velden, J.; Mittrucker, H.; Sparwasser, T.; Panzer, U. & Tiegs, G. (2011), 'Regulatory T cells control the Th1 immune response in murine crescentic glomerulonephritis.', Kidney Int 80 (2) , 154-164 .
[Kurzfassung]   [BibTeX]  [Endnote] 

Wheeler, K.; Tardif, S.; Rival, C.; Luu, B.; Bui, E.; Del Rio, R.; Teuscher, C.; Sparwasser, T.; Hardy, D. & Tung, K. (2011), 'Regulatory T cells control tolerogenic versus autoimmune response to sperm in vasectomy.', Proc Natl Acad Sci U S A 108 (18) , 7511-7516 .
[Kurzfassung]   [BibTeX]  [Endnote] 

Hackl, D.; Loschko, J.; Sparwasser, T.; Reindl, W. & Krug, A. (2011), 'Activation of dendritic cells via TLR7 reduces Foxp3 expression and suppressive function in induced Tregs.', Eur J Immunol 41 (5) , 1334-1343 .
[Kurzfassung]   [BibTeX]  [Endnote] 

McNally, A.; Hill, G.; Sparwasser, T.; Thomas, R. & Steptoe, R. (2011), 'CD4+CD25+regulatory T cells control CD8+ T-cell effector differentiation by modulating IL-2 homeostasis.', Proc Natl Acad Sci U S A 108 (18) , 7529-7534 .
[Kurzfassung]   [BibTeX]  [Endnote] 

Seung, E.; Cho, J.; Sparwasser, T.; Medoff, B. & Luster, A. (2011), 'Inhibiting CXCR3-dependent CD8+ T cell trafficking enhances tolerance induction in a mouse model of lung rejection.', J Immunol 186 (12) , 6830-6838 .
[Kurzfassung]   [BibTeX]  [Endnote] 

Olivier, A.; Sainz-Perez, A.; Dong, H.; Sparwasser, T.; Majlessi, L. & Leclerc, C. (2011), 'The adjuvant effect of TLR agonists on CD4(+) effector T cells is under the indirect control of regulatory T cells.', Eur J Immunol 41 (8) , 2303-2313 .
[Kurzfassung]   [BibTeX]  [Endnote] 

Weiss, E.; Schmidt, A.; Vobis, D.; Garbi, N.; Lahl, K.; Mayer, C.; Sparwasser, T.; Ludwig, A.; Suri-Payer, E.; Oberle, N. & Krammer, P. (2011), 'Foxp3-mediated suppression of CD95L expression confers resistance to activation-induced cell death in regulatory T cells.', J Immunol 187 (4) , 1684-1691 .
[Kurzfassung]   [BibTeX]  [Endnote] 

Woller, N.; Knocke, S.; Mundt, B.; Gurlevik, E.; Struver, N.; Kloos, A.; Boozari, B.; Schache, P.; Manns, M.; Malek, N.; Sparwasser, T.; Zender, L.; Wirth, T.; Kubicka, S. & Kuhnel, F. (2011), 'Virus-induced tumor inflammation facilitates effective DC cancer immunotherapy in a Treg-dependent manner in mice.', J Clin Invest 121 (7) , 2570-2582 .
[Kurzfassung]   [BibTeX]  [Endnote] 

Beyer, M.; Thabet, Y.; Muller, R.; Sadlon, T.; Classen, S.; Lahl, K.; Basu, S.; Zhou, X.; Bailey-Bucktrout, S.; Krebs, W.; Schonfeld, E.; Bottcher, J.; Golovina, T.; Mayer, C.; Hofmann, A.; Sommer, D.; Debey-Pascher, S.; Endl, E.; Limmer, A.; Hippen, K.; Blazar, B.; Balderas, R.; Quast, T.; Waha, A.; Mayer, G.; Famulok, M.; Knolle, P.; Wickenhauser, C.; Kolanus, W.; Schermer, B.; Bluestone, J.; Barry, S.; Sparwasser, T.; Riley, J. & Schultze, J. (2011), 'Repression of the genome organizer SATB1 in regulatory T cells is required for suppressive function and inhibition of effector differentiation.', Nat Immunol 12 (9) , 898-907 .
[Kurzfassung]   [BibTeX]  [Endnote] 

Kastenmuller, W.; Gasteiger, G.; Subramanian, N.; Sparwasser, T.; Busch, D.; Belkaid, Y.; Drexler, I. & Germain, R. (2011), 'Regulatory T Cells Selectively Control CD8+ T Cell Effector Pool Size via IL-2 Restriction.', J Immunol 187 (6) , 3186-3197 .
[Kurzfassung]   [BibTeX]  [Endnote] 

Tacken, P.; Ginter, W.; Berod, L.; Cruz, L.; Joosten, B.; Sparwasser, T.; Figdor, C. & Cambi, A. (2011), 'Targeting DC-SIGN via its neck region leads to prolonged antigen residence in early endosomes, delayed lysosomal degradation, and cross-presentation.', Blood 118 (15) , 4111-4119 .
[BibTeX]  [Endnote] 

Tse, B.; Russell, P.; Lochner, M.; Forster, I. & Power, C. (2011), 'IL-18 Inhibits Growth of Murine Orthotopic Prostate Carcinomas via Both Adaptive and Innate Immune Mechanisms.', PLoS One 6 (9) , e24241 .
[BibTeX]  [Endnote] 

Lochner, M. (2011), 'Tertiary lymphoid tissues in the colon: friend and foe.', Gut Microbes 2 (3) , 193-197 .
[BibTeX]  [Endnote] 

Schwarz, A.; Navid, F.; Sparwasser, T.; Clausen, B. & Schwarz, T. (2011), 'In vivo reprogramming of UV radiation-induced regulatory T-cell migration to inhibit the elicitation of contact hypersensitivity.', J Allergy Clin Immunol 128 (4) , 826-833 .
[BibTeX]  [Endnote] 

Baru, A.; Krishnaswamy, J.; Rathinasamy, A.; Scherr, M.; Eder, M. & Behrens, G. (2011), 'Dendritic cells derived from HOXB4-immortalized hematopoietic bone marrow cells.', Exp Biol Med (Maywood) 236 (11) , 1291-1297 .
[BibTeX]  [Endnote] 

Wilhelm, C.; Hirota, K.; Stieglitz, B.; Van Snick, J.; Tolaini, M.; Lahl, K.; Sparwasser, T.; Helmby, H. & Stockinger, B. (2011), 'An IL-9 fate reporter demonstrates the induction of an innate IL-9 response in lung inflammation.', Nat Immunol 12 (11) , 1071-1077 .
[BibTeX]  [Endnote] 

Baru, A.; Krishnaswamy, J.; Rathinasamy, A.; Scherr, M.; Eder, M. & Behrens, G. (2011), 'Dendritic cells derived from HOXB4-immortalized hematopoietic bone marrow cells', Exp Biol Med ( Maywood ) 236 (4) , 1291-1297 .
[Kurzfassung]   [BibTeX]  [Endnote] 

Lahl, K. & Sparwasser, T. (2011), 'In vivo depletion of Foxp3+ Tregs using the DEREG mouse model', Methods in Molecular Biology (in press) Review n/a , n/a .
[Kurzfassung]   [BibTeX]  [Endnote] 

Hadis, U.; Wahl, B.; Schulz, O.; Schippers, A.; Wagner, N.; Mueller, W.; Sparwasser, T.; Foerster, R. & Pabst, O. (2011), 'Cooperation of lymph nodes and intestinal lamina propria in FoxP3+ regulatory T cell mediated intestinal tolerance', Immunity (in press) n/a , n/a .
[BibTeX]  [Endnote] 

in press

Berod, L.; Puttur, F.; Huehn, J. & Sparwasser, T. (in press), 'Tregs in infection and vaccinology: heroes or traitors?', Microb Biotechnol n/a , n/a .
[Kurzfassung]   [BibTeX]  [Endnote] 

Cassani, B.; Villablanca, E.; Quintana, F.; Love, P.; Lacy-Hulbert, A.; Blaner, W.; Sparwasser, T.; Snapper, S.; Weiner, H. & Mora, J. (in press), 'Gut-tropic T Cells that Express Integrin alpha4beta7 and CCR9 are Required for Induction of Oral Immune Tolerance in Mice.', Gastroenterology n/a , n/a .
[BibTeX]  [Endnote] 

Hellingman, A.; van der Vlugt, L.; Lijkwan, M.; Bastiaansen, A.; Sparwasser, T.; Smits, H.; Hamming, J. & Quax, P. (in press), 'A limited role for regulatory T cells in post-ischemic neovascularization.', J Cell Mol Med n/a , n/a .
[Kurzfassung]   [BibTeX]  [Endnote] 

Lo Re, S.; Lecocq, M.; Uwambayinema, F.; Yakoub, Y.; Delos, M.; Demoulin, J.; Lucas, S.; Sparwasser, T.; Renauld, J.; Lison, D. & Huaux, F. (in press), 'PDGF-Producing CD4+ Foxp3+ Regulatory T Lymphocytes Promote Lung Fibrosis.', Am J Respir Crit Care Med n/a , n/a .
[BibTeX]  [Endnote] 

Onder, L.; Scandella, E.; Chai, Q.; Firner, S.; Mayer, C.; Sparwasser, T.; Thiel, V.; Rülicke, T. & Burkhard, L. (in press), 'Assessing stromal cell antigen presentation in a novel podoplanin: Cre-recombinase BAC-transgenic mouse model.', Frontiers in Immunology n/a (n/a) , n/a .
[BibTeX]  [Endnote] 

Panzer, M.; Wirth, S.; Drexler, I.; Sparwasser, T. & Voehringer, D. (in press), 'Rapid in vivo conversion of effector T cells into Th2 cells during helminth infection.', J Immunol n/a , n/a .
[BibTeX]  [Endnote] 

Zhao, E.; Wang, L.; Dai, J.; Kryczek, I.; Wei, S.; Vatan, L.; Altuwaijri, S.; Sparwasser, T.; Wang, G.; Keller, E. & Zou, W. (in press), 'Regulatory T cells in the bone marrow microenvironment in patients with prostate cancer.', OncoImmunology n/a , n/a .
[BibTeX]  [Endnote] 

2010

Anz, D.; Koelzer, V.; Moder, S.; Thaler, R.; Schwerd, T.; Lahl, K.; Sparwasser, T.; Besch, R.; Poeck, H.; Hornung, V.; Hartmann, G.; Rothenfusser, S.; Bourquin, C. & Endres, S. (2010), 'Immunostimulatory RNA blocks suppression by regulatory T cells', J Immunol 184 (184(2)) , 939-946 .
[Kurzfassung]   [BibTeX]  [Endnote] 

Arnold, I.; Lee, J.; Amieva, M.; Roers, A.; Flavell, R.; Sparwasser, T. & Muller, A. (2010), 'Tolerance rather than immunity protects from Helicobacter pylori-induced gastric preneoplasia', Gastroenterology 140 (140(1)) , 199-209 .
[Kurzfassung]   [BibTeX]  [Endnote] 

Baru, A.; Hartl, A.; Lahl, K.; Krishnaswamy, J.; Fehrenbach, H.; Yildirim, A.; Garn, H.; Renz, H.; Behrens, G. & Sparwasser, T. (2010), 'Selective depletion of Foxp3+ regulatory T cells during sensitization phase aggravates experimental allergic airway inflammation', J Immunol 40 (40(8)) , 2259-2266 .
[Kurzfassung]   [BibTeX]  [Endnote] 

Boissonnas, A.; Scholer-Dahirel, A.; Simon-Blancal, V.; Pace, L.; Valet, F.; Kissenpfennig, A.; Sparwasser, T.; Malissen, B.; Fetler, L. & Amigorenga, S. (2010), 'FoxP3+ T cells induce perforin-dependent dendritic cell death in tumor-draining lymph nodes', Immunity 32 (2) , 266-278 .
[Kurzfassung]   [BibTeX]  [Endnote] 

Engel, D.; Koscielny, A.; Wehner, S.; Maurer, J.; Schiwon, M.; Franken, L.; Schumak, B.; Limmer, A.; Sparwasser, T.; Hirner, A.; Knolle, P.; Kalff, J. & Kurts, C. (2010), 'Th1 memory cells disseminate postoperative ileus over the entire intestinal tract', Nat Med 16 (16(12)) , 1407-1713 .
[Kurzfassung]   [BibTeX]  [Endnote] 

Haque, A.; Best, S.; Amante, F.; Mustafah, S.; Desbarrieres, L.; Labastida, F.; Sparwasser, T.; Hill, G. & Engwerda, C. (2010), 'CD4+ natural regulatory T cells prevent experimental cerebral malaria via CTLA-4 when expanded in vivo', PloS Pathogens 6 (6(12)) , e1001221 .
[Kurzfassung]   [BibTeX]  [Endnote] 

Hubert, S.; Rissiek, B.; Klages, K.; Huehn, J.; Sparwasser, T.; Haag, F.; Koch-Nolte, F.; Boyer, O.; Seman, M. & Adriouch, S. (2010), 'Extracellular NAD+ shapes the Foxp3+ regulatory T cell compartment through the ART2/P2X7 pathway.', JEM 207 (207(12)) , 2561-2568 .
[Kurzfassung]   [BibTeX]  [Endnote] 

Klages, K.; Mayer, C.; Lahl, K.; Loddenkemper, C.; Teng, M.; Ngiow, S.; Smyth, M.; Hamann, A.; Huehn, J. & Sparwasser, T. (2010), 'Selective depletion of Foxp3+ regulatory T cells improves effective therapeutic vaccination against established melanoma', Cancer Research 70 (70(20)) , 7788-7799 .
[Kurzfassung]   [BibTeX]  [Endnote] 

Navarro, S.; Cossalter, G.; Chiavaroli, C.; Kanda, A.; Fleury, S.; Lazzari, A.; Cazareth, J.; Sparwasser, T.; Dombrowicz, D.; Glaichenhaus, N. & Julia, V. (2010), 'The oral administration of bacterial extracts prevents asthma via the recruitment of regulatory T cells to the airways', Mucosal Immunol 4 (4(1)) , 53-65 .
[Kurzfassung]   [BibTeX]  [Endnote] 

Pechloff, K.; Holch, J.; Ferch, U.; Schweneker, M.; Kremer, M.; Sparwasser, T.; Quintanilla-Martinez, L.; Gewies, A.; Peschel, C. & Ruland, J. (2010), 'The fusion kinase ITK-SYK mimics a T-cell receptor signal and drives oncogenesis in conditional mouse models of peripheral T-cell lymphoma', J Exp Med 207 (207(5)) , 1031-1044 .
[Kurzfassung]   [BibTeX]  [Endnote] 

Sawa, S.; Cherrier, M.; Lochner, M.; Satoh-Takayama, N.; Fehling, H.; Langa, F.; Santo, J. D. & Eberl, G. (2010), 'Lineage relationship analysis of ROR?t+ innate lymphoid cells', Science 330 (6004) , 665-669 .
[Kurzfassung]   [BibTeX]  [Endnote] 

Schildknecht, A.; Brauer, S.; Brenner, C.; Lahl, K.; Schild, H.; Sparwasser, T.; Probst, H. & van den Broek, M. (2010), 'FoxP3+ regulatory T cells essentially contribute to peripheral CD8+ T cell tolerance induced by steady state dendritic cells', Proc Nate Acad Sci 107 (107(1)) , 199-203 .
[Kurzfassung]   [BibTeX]  [Endnote] 

Suttner, K.; Depner, M.; Klopp, N.; von Mutius, E.; Illig, T.; Sparwasser, T. & Kabesch, M. (2010), 'Genetic variants harbouring the FOXP3 locus increase hay fever risk', J Allergy Clin Immunol 125 (125(6)) , 1395-1399 .
[Kurzfassung]   [BibTeX]  [Endnote] 

Teng, M.; Ngiow, S.; von Scheidt, B.; McLaughlin, N.; Sparwasser, T. & Smyth, M. (2010), 'Conditional regulatory T-cell depletion releases adaptive immunity preventing carcinogenesis and suppressing established tumor growth.', Cancer Research 70 (70(20)) , 7800-7809 .
[Kurzfassung]   [BibTeX]  [Endnote] 

2009

Hamm, S.; Latz, E.; Hangel, D.; Mueller, T.; Yu, P.; Golenbock, D.; Sparwasser, T.; Wagner, H. & Bauer, S. (2009), 'Alternating 2?-O-ribose methylation is a universal approach for generating non-stimulatory siRNA by acting as TLR7 antagonist', Immunobiology 215 (7) , 559-569 .
[Kurzfassung]   [BibTeX]  [Endnote] 

Kim, J.; Lahl, K.; Hori, S.; Loddenkemper, C.; Chaudhry, A.; Deroos, P.; Rudensky, A. & Sparwasser, T. (2009), 'Cutting Edge: Depletion of Foxp3+ Cells leads to induction of autoimmunity by specific ablation of regulatory T cells in genetically targeted mice', J Immunol 183 (183(12)) , 7631-7634 .
[Kurzfassung]   [BibTeX]  [Endnote] 

Lahl, K.; Mayer, C.; Bopp, T.; Huehn, J.; Loddenkemper, C.; Eberl, G.; Wirnsberger, G.; Dornmair, K.; Geffers, R.; Schmitt, E.; Buer, J. & Sparwasser, T. (2009), 'Nonfunctional regulatory T cells and defective control of Th2 Cytokine production in natural scurfy mutant mice', J Immunol 183 (183(9)) , 5662-5672 .
[Kurzfassung]   [BibTeX]  [Endnote] 

Pellegrini, M.; Calzascia, T.; Elford, A.; Shahinian, A.; Lin, A.; Dissanayake, D.; Dhanji, S.; Nguyen, L.; Gronski, M.; Morre, M.; Assouline, B.; Lahl, K.; Sparwasser, T.; Ohashi, P. & Mak, T. (2009), 'Adjuvant IL-7 antagonizes multiple cellular and molecular inhibitory networks to enhance immunotherapies', Nat Med 15 (15(5)) , 528-536 .
[Kurzfassung]   [BibTeX]  [Endnote] 

Rausch, S.; Huehn, J.; Loddenkemper, C.; Hepworth, M.; Klotz, C.; Sparwasser, T.; Hamann, A.; Lucius, R. & Hartmann, S. (2009), 'Establishment of nematode infection despite increased Th2 responses and immunopathology after selective depletion of Foxp3(+) Cells', Eur J Immunol 39 (39(11)) , 3066-3077 .
[Kurzfassung]   [BibTeX]  [Endnote] 

Siegemund, S.; Hartl, A.; von Buttlar, H.; Dautel, F.; Raue, R.; Freudenberg, M.; Fejer, G.; Buttner, M.; Koehler, G.; Kirschning, C.; Sparwasser, T. & Alber, G. (2009), 'Conventional bone marrow-derived dendritic cells contribute to toll-like receptor-independent production of alpha/beta interferon in response to inactivated parapoxvirus ovis', J Virol 83 (83(18)) , 9411-9422 .
[Kurzfassung]   [BibTeX]  [Endnote] 

Singh, S.; Stephani, J.; Schaefer, M.; Kalay, H.; Garcia-Vallejo, J.; den Haan, J.; Saeland, E.; Sparwasser, T. & van Kooyk, Y. (2009), 'Targeting glycan modified OVA to murine DC-SIGN-transgenic dendritic cells enhances MHC class I and II presentation', Molecular Immunol 47 (47(2-3)) , 164-174 .
[Kurzfassung]   [BibTeX]  [Endnote] 

Steeg, C.; Adler, G.; Sparwasser, T.; Fleischer, B. & Jacobs, T. (2009), 'Limited role of CD4+Foxp3+ regulatory T cells in the control of experimental cerebral malaria', J Immunol 183 (183(11)) , 7014-7022 .
[Kurzfassung]   [BibTeX]  [Endnote] 

von Allmen, C.; Schmitz, N.; Bauer, M.; Hinton, H.; Kurrer, M.; Buser, R.; Gwerder, M.; Muntwiler, S.; Sparwasser, T.; Beerli, R. & Bachmann, M. (2009), 'Secretory phospholipase A2-IID is an effector molecule of CD4+CD25+ regulatory T cells', Proc Nate Acad Sci 106 (106(28)) , 11673-11678 .
[Kurzfassung]   [BibTeX]  [Endnote] 

Zelinskyy, G.; Dietze, K.; Sparwasser, T. & Dittmer, U. (2009), 'Regulatory T cells suppress antiviral immune responses and increase viral loads during acute infection with a lymphotropic retrovirus', PloS Pathogens 5 (5(8)) , e1000406 .
[Kurzfassung]   [BibTeX]  [Endnote] 

Zelinskyy, G.; Dietze, K.; Huesecken, Y.; Schimmer, S.; Nair, S.; Werner, T.; Gibbert, K.; Kershaw, O.; Gruber, A.; Sparwasser, T. & Dittmer, U. (2009), 'The regulatory T cell response during acute retroviral infection is locally defined and controls the magnitude and duration of the virus-specific cytotoxic T cell response', Blood 114 (114(15)) , 3199-3207 .
[Kurzfassung]   [BibTeX]  [Endnote] 

2008

Heit, A.; Gebhardt, F.; Lahl, K.; Neuenhahn, M.; Schmitz, F.; Anderl, F.; Wagner, H.; Sparwasser, T.; Busch, D. & Kastenmuller, K. (2008), 'Circumvention of regulatory CD4(+) T cell activity during cross-priming strongly enhances T cell-mediated immunity', Eur J Immunol 38 (38(6)) , 1585-1597 .
[Kurzfassung]   [BibTeX]  [Endnote] 

Osorio, F.; LeibundGut-Landmann, S.; Lochner, M.; Lahl, K.; Sparwasser, T.; Eberl, G.; Reis, E. & Sousa, C. (2008), 'DC activated via dectin-1 convert Treg into IL-17 producers', Eur J Immunol 38 (38(12)) , 3274-3281 .
[Kurzfassung]   [BibTeX]  [Endnote] 

Schaefer, M.; Reiling, N.; Fessler, C.; Stephani, J.; Taniuchi, I.; Hatam, F.; Yildirim, A.; Fehrenbach, H.; Walter, K.; Ruland, J.; Wagner, H.; Ehlers, S. & Sparwasser, T. (2008), 'Decreased pathology and prolonged survival of human DC-SIGN transgenic mice during mycobacterial infection', J Immunol 180 (180(10)) , 6836-6845 .
[Kurzfassung]   [BibTeX]  [Endnote] 

2007

Lahl, K.; Loddenkemper, C.; Drouin, C.; Freyer, J.; Arnason, J.; Eberl, G.; Hamann, A.; Wagner, H.; Huehn, J. & Sparwasser, T. (2007), 'Selective depletion of Foxp3+ regulatory T cells induces a scurfy-like disease', J Exp Med 204 (1) , 57-63 .
[BibTeX]  [Endnote] 

Sparwasser, T. & Eberl, G. (2007), 'BAC to immunology--bacterial artificial chromosome-mediated transgenesis for targeting of immune cells', Immunology 121 (3) , 308-313 .
[Kurzfassung]   [BibTeX]  [Endnote] 

2006

(2006), 'The Bcl10-Malt1 complex segregates Fc epsilon RI-mediated nuclear factor kappa B activation and cytokine production from mast cell degranulation.', (203(2)) .
[Kurzfassung]   [BibTeX]  [Endnote] 

Gross, O.; Gewies, A.; Finger; Schafer, M.; Sparwasser, T.; Peschel, C.; Forster, I. & Ruland, J. (2006), 'Card9 controls a non-TLR signalling pathway for innate anti-fungal immunity', Nature 442 (7103) , 651-656 .
[Kurzfassung]   [BibTeX]  [Endnote] 

Klemm, S.; Gutermuth, J.; Hultner, L.; Sparwasser, T.; Behrendt, H.; Peschel, C.; Mak, T.; Jakob, T. & Ruland, J. (2006), 'The Bcl10-Malt1 complex segregates Fc epsilon RI-mediated nuclear factor kappa B activation and cytokine production from mast cell degranulation', J Exp Med 203 (2) , 337-347 .
[BibTeX]  [Endnote] 

von Meyenn, F.; Schaefer, M.; Weighardt, H.; Bauer, S.; Kirschning, C.; Wagner, H. & Sparwasser, T. (2006), 'Toll-like receptor 9 contributes to recognition of Mycobacterium bovis Bacillus Calmette-Guerin by Flt3-ligand generated dendritic cells', Immunobiology 211 (6-8) , 557-565 .
[Kurzfassung]   [BibTeX]  [Endnote] 

2004

Sparwasser, T.; Gong, S.; Li, J. & Eberl, G. (2004), 'General method for the modification of different BAC types and the rapid generation of BAC transgenic mice', Genesis 38 (1) , 39-50 .
[Kurzfassung]   [BibTeX]  [Endnote] 

2002

Jung, S.; Unutmaz, D.; Wong, P.; Sano, G.; los Santos, K. D.; Sparwasser, T.; Wu, S.; Vuthoori, S.; Ko, K.; Zavala, F.; Pamer, E.; Littman, D. & Lang, R. (2002), 'In vivo depletion of CD11c(+) dendritic cells abrogates priming of CD8(+) T cells by exogenous cell-associated antigens', Immunity 17 (2) , 211-220 .
[Kurzfassung]   [BibTeX]  [Endnote] 

2001

Baribaud, F.; Pohlmann, S.; Sparwasser, T.; Kimata, M.; Choi, Y.; Haggarty, B.; Ahmad, N.; Macfarlan, T.; Edwards, T.; Leslie, G.; Arnason, J.; Reinhart, T.; Kimata, J.; Littman, D.; Hoxie, J. & Doms, R. (2001), 'Functional and antigenic characterization of human, rhesus macaque, pigtailed macaque, and murine DC-SIGN', J Virol 75 (75(21)) , 10281-10289 .
[Kurzfassung]   [BibTeX]  [Endnote] 

2000

Decker, T.; Schneller, F.; Sparwasser, T.; Tretter, T.; Lipford, G.; Wagner, H. & Peschel, C. (2000), 'Immunostimulatory CpG-oligonucleotides cause proliferation, cytokine production, and an immunogenic phenotype in chronic lymphocytic leukemia B cells', Blood 95 (3) , 999-1006 .
[Kurzfassung]   [BibTeX]  [Endnote] 

Lipford, G.; Sparwasser, T.; Zimmermann, S.; Heeg, K. & Wagner, H. (2000), 'CpG-DNA-mediated transient lymphadenopathy is associated with a state of Th1 predisposition to antigen-driven responses', J Immunol 165 (165(3)) , 1228-1235 .
[Kurzfassung]   [BibTeX]  [Endnote] 

Lipford, G. & Sparwasser, T. (2000), 'Hematopoietic remodeling triggered by CpG DNA', Curr Top Microbiol Immunol 247 , 119-129 .
[Kurzfassung]   [BibTeX]  [Endnote] 

Sparwasser, T.; Vabulas, R.; Villmow, B.; Lipford, G. & Wagner, H. (2000), 'Bacterial CpG-DNA activates dendritic cells in vivo: T helper cell-independent cytotoxic T cell responses to soluble proteins', Curr Top Microbiol Immunol 30 (30(12)) , 3591-3597 .
[Kurzfassung]   [BibTeX]  [Endnote] 

Sparwasser, T. & Lipford, G. (2000), 'Consequences of bacterial CpG DNA-driven activation of antigen-presenting cells', Curr Top Microbiol Immunol 247 , 59-75 .
[Kurzfassung]   [BibTeX]  [Endnote] 

1999

Sparwasser, T.; Hultner, L.; Koch, E.; Luz, A.; Lipford, G. & Wagner, H. (1999), 'Immunostimulatory CpG-oligodeoxynucleotides cause extramedullary murine hemopoiesis', J Immunol (162(4)) .
[Kurzfassung]   [BibTeX]  [Endnote] 

1998

Hacker, H.; Mischak, H.; Miethke, T.; Liptay, S.; Schmid, R.; Sparwasser, T.; Heeg, K.; Lipford, G. & Wagner, H. (1998), 'CpG-DNA-specific activation of antigen-presenting cells requires stress kinase activity and is preceded by non-specific endocytosis and endosomal maturation', Embo J 17 (17(21)) , 6230-6240 .
[Kurzfassung]   [BibTeX]  [Endnote] 

Heeg, K.; Sparwasser, T.; Lipford, G.; Hacker, H.; Zimmermann, S. & Wagner, H. (1998), 'Bacterial DNA as an evolutionary conserved ligand signalling danger of infection to immune cells', Eur J Clin Microbiol Infect Dis 17 (17(7)) , 464-469 .
[Kurzfassung]   [BibTeX]  [Endnote] 

Sparwasser, T.; Koch, E.; Vabulas, R.; Heeg, K.; Lipford, G.; Ellwart, J. & Wagner, H. (1998), 'Bacterial DNA and immunostimulatory CpG oligonucleotides trigger maturation and activation of murine dendritic cells', Eur J Immunol 28 (28(6)) , 2045-2054 .
[Kurzfassung]   [BibTeX]  [Endnote] 

1997

Lipford, G.; Sparwasser, T.; Bauer, M.; Zimmermann, S.; Koch, E.; Heeg, K. & Wagner, H. (1997), 'Immunostimulatory DNA: sequence-dependent production of potentially harmful or useful cytokines', Eur J Immunol 27 (27(12)) , 3420-3426 .
[Kurzfassung]   [BibTeX]  [Endnote] 

Sparwasser, T.; Miethke, T.; Lipford, G.; Borschert, K.; Hacker, H.; Heeg, K. & Wagner, H. (1997), 'Bacterial DNA causes septic shock', Nature 386 (6623) , 336-337 .
[Kurzfassung]   [BibTeX]  [Endnote] 

Sparwasser, T.; Miethke, T.; Lipford, G.; Erdmann, A.; Hacker, H.; Heeg, K. & Wagner, H. (1997), 'Macrophages sense pathogens via DNA motifs: induction of tumor necrosis factor-alpha-mediated shock', Eur J Immunol 27 (27(7)) , 1671-1679 .
[Kurzfassung]   [BibTeX]  [Endnote]